{"title":"一种用于再生医学的新型可注射组织工程支架","authors":"H. Hosseinkhani, M. Hosseinkhani, H. Kobayashi","doi":"10.1109/MMB.2006.251477","DOIUrl":null,"url":null,"abstract":"The failure of the application of tissue engineering in clinical trials is questionable. Tissue-engineering scaffolds used in tissue regeneration have micron structures that fail to be analogous to native extracellular matrix (ECM) in terms of both chemical composition and physical structure as a suitable surface structure for cell attachment, proliferation, and differentiation. In this study we designed an artificial ECM in order to mimic the nano-structured topography created by ECM components of native tissue. Selective differentiation of cardiomyocytes cells by self assembly of peptide-amphiphile nanofibers was studied for in vivo cardiac infarction therapy","PeriodicalId":170356,"journal":{"name":"2006 International Conference on Microtechnologies in Medicine and Biology","volume":"2013 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2006-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A new injectable tissue engineered scaffold for regenerative medicine\",\"authors\":\"H. Hosseinkhani, M. Hosseinkhani, H. Kobayashi\",\"doi\":\"10.1109/MMB.2006.251477\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The failure of the application of tissue engineering in clinical trials is questionable. Tissue-engineering scaffolds used in tissue regeneration have micron structures that fail to be analogous to native extracellular matrix (ECM) in terms of both chemical composition and physical structure as a suitable surface structure for cell attachment, proliferation, and differentiation. In this study we designed an artificial ECM in order to mimic the nano-structured topography created by ECM components of native tissue. Selective differentiation of cardiomyocytes cells by self assembly of peptide-amphiphile nanofibers was studied for in vivo cardiac infarction therapy\",\"PeriodicalId\":170356,\"journal\":{\"name\":\"2006 International Conference on Microtechnologies in Medicine and Biology\",\"volume\":\"2013 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2006-05-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2006 International Conference on Microtechnologies in Medicine and Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/MMB.2006.251477\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2006 International Conference on Microtechnologies in Medicine and Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MMB.2006.251477","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A new injectable tissue engineered scaffold for regenerative medicine
The failure of the application of tissue engineering in clinical trials is questionable. Tissue-engineering scaffolds used in tissue regeneration have micron structures that fail to be analogous to native extracellular matrix (ECM) in terms of both chemical composition and physical structure as a suitable surface structure for cell attachment, proliferation, and differentiation. In this study we designed an artificial ECM in order to mimic the nano-structured topography created by ECM components of native tissue. Selective differentiation of cardiomyocytes cells by self assembly of peptide-amphiphile nanofibers was studied for in vivo cardiac infarction therapy
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
