Pakistan Journal of Ophthalmology最新文献_第4页

Comparison of α-Smooth Muscle Actin (α-SMA) and Collagen Type III Expression after Conjunctival Excision Between Platelet-Rich Fibrin (PRF) Membrane and Conjunctival Autograft Treatment: An Animal Model Experimental Study on Oryctolagus cuniculus 富血小板纤维蛋白（PRF）膜和结膜自体移植治疗结膜切除术后α-平滑肌肌动蛋白（α-SMA）和胶原Ⅲ型表达的比较：一项针对兔的动物模型实验研究

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1760

Indri Wahyuni, Reni Prastyani, Agung Bhakti Wiratama, Ismi Zuhria, T. V. Widiyatno

{"title":"Comparison of α-Smooth Muscle Actin (α-SMA) and Collagen Type III Expression after Conjunctival Excision Between Platelet-Rich Fibrin (PRF) Membrane and Conjunctival Autograft Treatment: An Animal Model Experimental Study on Oryctolagus cuniculus","authors":"Indri Wahyuni, Reni Prastyani, Agung Bhakti Wiratama, Ismi Zuhria, T. V. Widiyatno","doi":"10.36351/pjo.v40i2.1760","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1760","url":null,"abstract":"Purpose: To evaluate the impact of Platelet-Rich Fibrin (PRF) membrane and conjunctival autografts on α-Smooth Muscle Actin (α-SMA) and type III collagen expression following conjunctival excision in Oryctolagus cuniculus.\u0000Study Design: Experimental study with a randomized post-test only design.\u0000Place and Duration of Study: Airlangga University, Surabaya in November 2022.\u0000Methods: Twenty rabbit eyes were categorized into two groups: those sutured with PRF membrane and those sutured with conjunctival autografts after temporal conjunctival excision. The study assessed α-SMA and type III collagen expression through the Immunoreactive Score (IRS) method.Data analysis is conducted using appropriate statistical methods, such as the t-test or Mann-Whitney U test, to compare the expression of α-SMA and collagen type III between the two groups.\u0000Results: The data for each sample represented the average IRS value observed at 200x magnification. In the conjunctival autograft group, the mean IRS of α-SMA expression was 5.52 ± 0.84,","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"61 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140761571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing the Technique of Eye Drop Administration through Evaluation and Education: A Quality Improvement Initiative 通过评估和教育提高滴眼液使用技术：质量改进计划

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1734

Marwa Saif, Fatima Shabbeer, Hareem Ilyas, Safa Saif, Usman Imtiaz

{"title":"Enhancing the Technique of Eye Drop Administration through Evaluation and Education: A Quality Improvement Initiative","authors":"Marwa Saif, Fatima Shabbeer, Hareem Ilyas, Safa Saif, Usman Imtiaz","doi":"10.36351/pjo.v40i2.1734","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1734","url":null,"abstract":"Purpose: To evaluate the eye-drop administration technique and see the effect of education in improving the eye drop delivery method.\u0000Study Design: Interventional case series.\u0000Place and Duration of Study: Central Park Teaching Hospital Lahore from May-2022 to September-2022\u0000Methods: This study includes 341 patients who had been self-administering eye drops as a treatment for glaucomaor any other disorder. The patients were asked to instill the drop by using a 5ml Systane bottle, as they should do at home. Two observers assessed the technique. Patients were educated about the techniques and they were re-assessed in the form of a post-test. They were evaluated by the same observers again. Data was analyzed suing Fisher’s Exact test.\u0000Results: A significant improvement was observed in several parameters, including the mean time (in seconds) taken to instill the first drop, the number of drops squeezed, the number of drops reaching the conjunctival sac at the first attempt, hand washing, shaking the bottle before instillation, tilting the head backwards during drop instillation, and the occurrence of drops falling on the cheek (p ≤ 0.05). Conversely, statistically insignificant improvements were noted in parameters such as touching the tip of the dropper and closing the eye for a minute.\u0000Conclusion: The findings underscore the importance of enhancing patient education regarding the correct technique for drop instillation.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"193 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140777789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual Loss Due to Optic Nerve Injury with Blunt Trauma: A Case Series 钝性外伤导致视神经损伤引起的视力丧失：病例系列

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1748

Afzal Bodla, Maria Afzal Bodla, Nalain syedah

引用次数: 0

Supratarsal Injection of Bevacizumab in the Treatment of Vernal Kerato Conjunctivitis 跗骨上注射贝伐珠单抗治疗疱疹性角膜炎

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1767

Z. Kamil, Fatima Ahmed, Saliha Naz, Muhammad Tanweer Hassan Khan

{"title":"Supratarsal Injection of Bevacizumab in the Treatment of Vernal Kerato Conjunctivitis","authors":"Z. Kamil, Fatima Ahmed, Saliha Naz, Muhammad Tanweer Hassan Khan","doi":"10.36351/pjo.v40i2.1767","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1767","url":null,"abstract":"Purpose: To evaluate the effectiveness of supratarsal injection of Bevacizumab in the treatment of Vernal Kerato-conjunctivitis (VKC).\u0000Study Design: Quasi experimental study.\u0000Place and Duration of Study: LRBT Karachi from September 2022 to September 2023.\u0000Methods: This study included 110 eyes of 60 patients with VKC and divided into two groups by convenient sampling. In one group (n=30) 0.1ml of Bevacizumab 2.5%was injected in supratarsal space with 27-gauge needle under topical anaesthesia. Other group (n=30) received conventional treatment. The sign and symptoms were checked at one week and at one month in all patients. The qualitative variables were presented as frequency and percentage while quantitative variables were shown as mean ± standard deviation. Chi square test was applied for comparison.\u0000Results: Mean age of the patients was 12.4 +1.9 years. There were 46 (76.0%) males. Itching and photophobia was not seen in 50% of the patients treated with Bevacizumab while this percentage was 13.3% and 10% respectively in case of conventional treatment. Similarly, redness, discharge and limbal papillae were not seen in 70%, 73.3% and 83.3% respectively after Bevacizumab application. While it was 16.6%, 30% and 10% respectively after conventional treatment. Significant improvement in itching, photophobia, redness, discharge and limbal papilla was observed in the group of patients who received supratarsal Bevacizumab injection as compared to those who received conventional treatment (p<0.05).\u0000Conclusion: Bevacizumab is a safe and effective treatment in patients of VKC refractory to conventional treatment.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"740 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140782506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual and Surgical Outcomes in Late Presentation of Retinal Detachment 视网膜脱离晚期患者的视力和手术效果

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1665

Bibi Rafeen Talpur, F. Wali, Shahzad Memon, Waqas Ali Suriho, Maryam Younus

{"title":"Visual and Surgical Outcomes in Late Presentation of Retinal Detachment","authors":"Bibi Rafeen Talpur, F. Wali, Shahzad Memon, Waqas Ali Suriho, Maryam Younus","doi":"10.36351/pjo.v40i2.1665","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1665","url":null,"abstract":"Purpose: To evaluate the frequency of treatment success in terms of visual and surgical outcomes in patients with late presentation of retinal detachment.\u0000Study Design: Quasi experimental.\u0000Place and Duration of Study: Sindh institute of Ophthalmology and visual Sciences from June 2022 to January 2023.\u0000Methods: A total of 50 eyes of 50 patients with delayed presentation of retinal detachment who underwent Pars Plana Vitrectomy (PPV) were included and followed up for 6 months. Preand post-surgery Best Corrected Visual Acuity (BCVA) and anatomical attachment of retina were comprehensively analyzed. Factors affecting an atomical success were also studied.\u0000Results: Mean age of patients was 47±18 years. Twenty seven patients were (54%) were more than 45 years of age and 32(64%) were males. Thirty eight (76%) patients achieved successful anatomical attachment of retina at 6th month follow-up. Post-operative BCVA also showed improvement in vision.Risk factors identified for poor anatomical and visual outcome following PPV for retinal detachment are; PVR advance stage, longer duration of visual symptoms and poor-presenting BCVA. Age, sex, laterality, Pre-operative BCVA, lens status, diagnosis, and type of surgery showed insignificant associations (P >0.05).\u0000Conclusion: Anatomical failure and poor functional outcomes appear to be mostly caused by PVR. PVR, longer duration of visual symptoms and poor-presenting VA are risk factors for poor anatomical and visual outcome following PPV surgery for RD. Late presentations to clinics can decrease with mass awareness. The frequency of proliferative vitreoretinopathy would decline, and visual results would be improved.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"126 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140767762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Choroidal Osteoma with Choroidal Neo Vascular Membrane 脉络膜骨瘤伴脉络膜新血管膜

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1769

Sivaranjani, Lita Pragnya, Manavi D Sindal, Roopa Saishekar

引用次数: 0

Comparison of Nd: YAG Laser Iridotomy Alone Versus Sequential Argon-Nd: YAG Laser Iridotomy in Patients with Primary Angle Closure Spectrum 原发性角膜闭合症患者单纯掺钕钇钕石榴石激光虹膜切开术与掺钕钇钕石榴石激光虹膜切开术的比较

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1765

Paras Khan, Rizwan Khan, Attia Ahmad, Farah Huma, Fatima Zafar

{"title":"Comparison of Nd: YAG Laser Iridotomy Alone Versus Sequential Argon-Nd: YAG Laser Iridotomy in Patients with Primary Angle Closure Spectrum","authors":"Paras Khan, Rizwan Khan, Attia Ahmad, Farah Huma, Fatima Zafar","doi":"10.36351/pjo.v40i2.1765","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1765","url":null,"abstract":"Purpose: To compare the mean Nd: YAG energy used and mean decrease in IOP 3-hours post-laser, in Nd: YAG Laser iridotomyalone versus sequential Argon-Nd:YAGiridotomy in patients with primary angle closure spectrum.\u0000Study Design: Quasi experimental Study.\u0000Place and Duration of Study: Department of Ophthalmology, Allied Hospital, Faisalabad from March 2022 to August 2022.\u0000Methods: After taking approval from Ethical review board, 70 patients with angle closure spectrumwere included in the study. Out of 70, 25 patients were primary angle closure suspect (PACS), 28 had primary angle closure (PAC) and 17 patients had primary angle closure glaucoma (PACG). We sorted patients into Group A (those who underwent sequential Argon-Nd: YAG Laser peripheral iridotomy) and Group B (those who underwent Nd: YAG laser alone). Mean Nd: YAG energy used was noted in each group and compared using SPSS version 25.0. Mean decrease in IOP 3-hours post-laser was also noted and compared.\u0000Results: Mean decrease in IOP 3 hours post-laser was 5.46 ± 3.70 mmHg for sequential Argon-Nd: YAG LPI versus 3.46 ± 2.38 mmHg for Nd: YAG LPI alone (p-value = 0.009). Mean Nd: YAG energy used in sequential Argon-Nd: YAG LPI group was significantly lesser when compared to Nd: YAG LPI alone group (32.70 ± 38.87 versus 139.37 ± 62.32 mJ) which was found to be statistically significant (p = 0.0001).\u0000Conclusion: Sequential Argon-Nd-YAG laser iridotomy uses significantly less Nd:YAG energy than conventional Nd:YAG only method with better IOP control.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"19 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140790535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Vitamin D3 Supplementation in the Treatment of Dry Eye Syndrome 补充维生素 D3 在治疗干眼症中的作用

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1766

Bushra Kanwal, A. Kiran, Muhammad Junaid Iqbal, Iqra Khalil, Aghna Maryam

{"title":"Role of Vitamin D3 Supplementation in the Treatment of Dry Eye Syndrome","authors":"Bushra Kanwal, A. Kiran, Muhammad Junaid Iqbal, Iqra Khalil, Aghna Maryam","doi":"10.36351/pjo.v40i2.1766","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1766","url":null,"abstract":"Purpose: The aim of this study was to evaluate the role of vitamin D3 supplementation in treating non-Sjogren dry eye (NSDE) patients compared to the conventional treatment with artificial tears.\u0000Study Design: Non-randomized controlled Trial.\u0000Place and duration of study: Rural Health Centre (RHC) Buchaal Kalan from September 2021 to July 2022\u0000Methods: This study allocated 108 patients with NSDE and hypovitaminosis D via two-arm parallel assignment. The sample was divided into two groups by non-probability purposive sampling. Group 1 received conventional treatment as artificial tears 4 times/day and group 2 was given oral vitamin D3 supplementation of 6000 IU daily along with artificial tears for a period of 90 days. The impact of oral vitamin D3 supplementation on NSDE was assessed by comparing means of ocular parameters of both groups over time. Tear break-up time (TBUT) in seconds and Schirmer’s test (ST) score in millimeters were primary outcome measures. The ocular surface disease index (OSDI) score and numerical pain rating scale (NPRS) were secondary outcome measures.\u0000Results: The mean age of patients in group 1 and group 2 was 34.98±8.64 and 34.87±8.79 respectively. Similarly, the mean serum 25 (OH) D level was 15.03±3.27 in group 1 and 14.93±3.26 in group 2. Results showed that OSDI and NPRS scores were decreased in both groups, however, TBUT and ST scores were improved in group 2.\u0000Conclusion: Oral vitamin D3 supplementation may serve as a new treatment option for NSDE patients having hypovitaminosis D.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140760037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revolutionizing Ophthalmology: The Empowering Role of Artificial Intelligence 变革眼科：人工智能的强大作用

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1807

Zahid Kamal Siddiqui, Muhammad Moin, Hafiza Sadia Imtiaz

引用次数: 0

Effects of 0.01% Atropine Eye Drops on Controlling Myopia Progression in School Age Children in Ophthalmology Department of a Tertiary Care Hospital 0.01% 阿托品滴眼液对控制一家三甲医院眼科学龄儿童近视发展的影响

Pakistan Journal of Ophthalmology Pub Date : 2023-12-04 DOI: 10.36351/pjo.v40i1.1531

R. Chaudhry, Tariq Aziz, N. Q. Khan, Mahwash Khan, Mehboob Dad

{"title":"Effects of 0.01% Atropine Eye Drops on Controlling Myopia Progression in School Age Children in Ophthalmology Department of a Tertiary Care Hospital","authors":"R. Chaudhry, Tariq Aziz, N. Q. Khan, Mahwash Khan, Mehboob Dad","doi":"10.36351/pjo.v40i1.1531","DOIUrl":"https://doi.org/10.36351/pjo.v40i1.1531","url":null,"abstract":"Purpose: To determine the effects of 0.01% atropine eye drops in controlling myopia progression in school age children presenting to Ophthalmology Department of a Tertiary Care Hospital.\u0000Study Design: Quasi experimental study.\u0000Place & Duration of Study: Department of ophthalmology Jinnah postgraduate Medical Center, JPMC Karachi and Advance Eye Clinic Karachi, Pakistan from July 2018 to July 2020.\u0000Methods: One hundred myopic patients (myopia of 0.5D to 13.0D) with age range of 6 – 14 years were recruited. Patients with astigmatism <-2.0D, other ocular or medical disease and history of laser or ocular surgery were excluded. Atropine group was instructed to instill Atropine 0.01% once at night time. Control group did not receive any treatment. Refraction was performed at all examinations with and without Cycloplegia along with fundoscopy and axial length measurements. The follow up frequency was at 3 monthly intervals. Data was analyzed using SPSS 22. To compare quantitative data between groups, t-test was used while for qualitative data Chi-square test was used.\u0000Results: Mean age was 9.21 ± 2.45 years. Out of 100, 57 were males. There was no statistical difference between atropine group vs control group in terms of baseline SER (spherical equivalent refraction), (p = 0.407) and baseline axial length (p = 0.892). Mean difference in SER from baseline to after completion of study two groups was statistically significant (p < 0.001). Mean difference in AL from baseline to end of study between two groups was also statistically significant (p < 0.001).\u0000Conclusion: Low concentration atropine 0.01% can be helpful in halting myopia progression.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"19 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138601723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0