Pakistan Journal of Ophthalmology最新文献_第3页

Comparison between Two Doses of Suprachoroidal Triamcinolone Acetonide among Cases of Resistant Diabetic Macular Edema 耐药性糖尿病黄斑水肿病例中两种剂量的脉络膜上曲安奈德的比较

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1756

Muhammad Zunair Aziz, Umar Kazi, Ali Zia, Nasir Memon, Abdul Qadeem

{"title":"Comparison between Two Doses of Suprachoroidal Triamcinolone Acetonide among Cases of Resistant Diabetic Macular Edema","authors":"Muhammad Zunair Aziz, Umar Kazi, Ali Zia, Nasir Memon, Abdul Qadeem","doi":"10.36351/pjo.v40i2.1756","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1756","url":null,"abstract":"Purpose: To compare the effectiveness and safety of two doses of supra-choroidal Triamcinolone Acetonide (TA)in patients of resistant diabetic macular edema.\u0000Study Design: Quasi experimental study.\u0000Place and Duration of Study: Al-Ibrahim Eye Hospital, Karachi, from April 2023 to September 2023.\u0000Methods: Thirty-two cases of resistant diabetic macular edema were selected using a convenient sampling technique and divided into two groups. Group A received a single suprachoroidal injection of TA at a concentration of 2 mg/0.1 ml, while Group B received the same drug via the same route at a concentration of 4 mg/0.1 ml. All cases were monitored for any serious adverse effects the following day. Follow-up checkups were conducted for all cases at 1, 3, and 6 months.\u0000Results: Mean age of patients for group A and B was 56.24±1.2and 56.33±2.6years respectively. Both the groups were equivalent in all ophthalmological measurements best corrected visual acuity, central macular thickness and intraocular pressure (BCVA, CMT, IOP) at baseline checkups. At 6thmonth follow up, both groups showed improved BCVA and decreased CMT compared to baseline, but group B had a significant increase in IOP (p = 0.001). Additionally, cataract progression was slower in group A.\u0000Conclusion: Both doses of suprachoroidal TA are equally effective in cases of resistant diabetic macular edema in terms of improved BCVA and reduced CMT. However, the lower dose (2mg/0.1 ml) showed advantages in terms of fewer complications, specifically less likelihood of raised intraocular pressure and cataract formation.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"116 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140772113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late-Onset Capsular Block Syndrome: A One Year Follow-up Case Report 晚发囊膜阻滞综合征：一年随访病例报告

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1676

Ludovico Iannetti1, David Shaholli, Mauro Salducci

引用次数: 0

Comparison of Fluorometholone 0.1% and Cyclosporine 0.05% in the Treatment of Vernal Keratoconjunctivitis 氟米龙 0.1%与环孢素 0.05%治疗疱性角结膜炎的比较

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1691

Ahmed Usman Khalid, Umaira Liaqat

{"title":"Comparison of Fluorometholone 0.1% and Cyclosporine 0.05% in the Treatment of Vernal Keratoconjunctivitis","authors":"Ahmed Usman Khalid, Umaira Liaqat","doi":"10.36351/pjo.v40i2.1691","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1691","url":null,"abstract":"Purpose: To compare the effectiveness of Fluorometholone 0.1% and Cyclosporine 0.05% in the treatment of vernal keratoconjunctivitis.\u0000Study Design: Quasi experimental study.\u0000Place and Duration of Study: Hayatabad Medical Complex, Peshawar from December 2020 to June 2021.\u0000Methods: This study includes 104 patients divided into 2 groups. Patients in Group A were given topical Fluorometholone 0.1% while group B were given topical Cyclosporine 0.05%. Signs and symptoms were graded from scale 0-10 at the start of treatment and then at day 7,14 and 30. Drug was considered effective if the final score was equal to or less than 3 at day 30.\u0000Results: Mean age of the patients was 9.96±2.722 years in group A and 10.02±2.790years in group B. Mean baseline score was 6.90±0.721 in group A and 5.87±0.768in group B. In group A, 45 (86.5%) patients showed effectiveness while in group B, 36 (69.2%) patients showed effective results. Fluorometholone gave superior results as compared to Cyclosporine in patients with severe disease i.e., baseline score ≥ 6.Systemic allergic associations were noted in44.2% patients in group A and 36.5% patients in group B.\u0000Conclusion: These findings suggest that Fluorometholone may be a preferable treatment option for vernal keratoconjunctivitis, particularly in cases of more severe disease. However, considerations regarding systemic allergic associations should also be taken into account when making treatment decisions.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"897 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140781994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atropine 0.01% Eye Drops for Myopia Control in a tertiary care center of Pakistan: An interventional case series 巴基斯坦一家三级医疗中心使用 0.01% 阿托品滴眼液控制近视：介入性病例系列

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1662

Tiabbah Saleem, S. Bokhari

{"title":"Atropine 0.01% Eye Drops for Myopia Control in a tertiary care center of Pakistan: An interventional case series","authors":"Tiabbah Saleem, S. Bokhari","doi":"10.36351/pjo.v40i2.1662","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1662","url":null,"abstract":"Purpose: To evaluate the real time results of once-dailyAtropine 0.01% eye drops in controlling myopia.\u0000Study Design: Interventional case series.\u0000Place and Duration of Study: The Eye Centre, South City Hospital, Karachi from September 2020 to August 2021.\u0000Methods: One hundred(both) eyes of 50 children were included in the study using non-probability consecutive sampling technique. Baseline spherical equivalent refraction(SER) was recorded at the initiation of treatment.The endpoint was measuring the rate of progression in SER at one year after treatment. Responders weredefined as the ones with either no progression of myopia or worsening of myopia of ≤ -0.50 SER and non-responders were defined as ones with a progression rate of myopia of greater than0.50 SER.\u0000Results: The baseline means SER for 100 eyes was 3.25±1.37 D. On follow-up after 12 months of treatment with Atropine 0.01% eye drops, the mean SER was -3.74 ± 1.34 D. The rate of SER progression was significantly lower at one year follow-up (p-value<0.001). The percentage of responders was84%.\u0000Conclusion: Significant reduction in myopia progression occurred after treatment with Atropine 0.01% eye drops in a greater percentage of children. This has led us to be confident in providing Atropine 0.01% eye drops along with simple spectacles as an effective treatment strategy to control myopia progression.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"37 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140759248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Familial Exudative Vitreoretinopathy: A Case Report 家族性渗出性玻璃体视网膜病变：病例报告

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1527

M. Tayyab, Kashif Iqbal, Awaid Abid

引用次数: 0

Correlation of Dysfunctional Lens Index with Lens Opacification System III in Age Related Cataract 老年性白内障患者晶状体功能障碍指数与晶状体不透明系统 III 的相关性

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1745

Zoomar Muzammil, Sharif Hashmani, Nauman Hashmani, Javaria Saleem, Aiman Monis

{"title":"Correlation of Dysfunctional Lens Index with Lens Opacification System III in Age Related Cataract","authors":"Zoomar Muzammil, Sharif Hashmani, Nauman Hashmani, Javaria Saleem, Aiman Monis","doi":"10.36351/pjo.v40i2.1745","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1745","url":null,"abstract":"Purpose: Age-Related changes in crystalline lens opacity and lens density contribute to formation of higher order aberrations resulting in reduced quality of vision. Precise quantification of cataract is important for predicting phacodynamics and educating patient. The iTrace(a ray-tracing aberrometer) provides Dysfunctional Lens Index (DLI). This study from Pakistan investigates the relationship between LOCS III and DLI in senile cataract.\u0000Study Design: Correlational study.\u0000Place and Duration of Study: Hashmanis Hospital, Karachi from March 2021 to May 2021.\u0000Methods: This study included 44 patients with age-related cataract. Demographic characteristics and complete ophthalmic examination of eyes including Best Corrected Visual Acuity (BCVA) and slit lamp biomicroscopy were performed. Age related cataracts were graded using the Standard technique of LOCS III. I-Trace was utilized for wave front analysis to calculate DLI.\u0000Results: BCVA and LOCS III nuclear opalescence score had strongest positive linear correlation (r=0.433, P<0.01). DLI displayed a strong significant negative correlation to LOCS III Cortical Cataract (C) and LOCS III Posterior Sub-Capsular Cataract (P) score (r=-0.415 and r=-0.694; respectively).\u0000Conclusion: BCVA had insignificant and small to no correlation to LOCS III C score and P score. Whereas, DLI showed the strongest significant correlation to LOCS III C score and P score. Patient's optical quality determined by visual symptoms are more closely associated to DLI parameter as compared to LOCS III classification. DLI can provide a better objective way to elevate age related cataract, monitor the progression and determine phacodynamics.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"43 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140797375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Awareness and Knowledge About RefractiveSurgery Among Medical Students in Baghdad 巴格达医学生对屈光手术的认识和了解

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1726

S. Rattan, Ruba Muayad Ridha, Batool Qahtan Majeed, Zahraa Zaki Hussien, Nabaa Ali Abduallah

{"title":"Awareness and Knowledge About RefractiveSurgery Among Medical Students in Baghdad","authors":"S. Rattan, Ruba Muayad Ridha, Batool Qahtan Majeed, Zahraa Zaki Hussien, Nabaa Ali Abduallah","doi":"10.36351/pjo.v40i2.1726","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1726","url":null,"abstract":"Purpose: Refractive error represents a common eye disorder that can significantly impact an individual's visual function and overall well-being. There are several methods of correcting refractive errors and objective of this study was to assess the awareness of refractive surgery and the preferred methods of refractive error correction among medical students in Baghdad.\u0000Study Design: Cross sectional survey.\u0000Place and Duration of Study: University of Baghdad Al-Kindy College of Medicinefrom November 2022 to March 2023.\u0000Methods: Medical students from six Baghdad medical colleges with total sample size of 350 were included. Students who had undergone refractive surgeries and fifth and sixth year medical students were also excluded. Level of knowledge was categorized as; <50% (0-5) poor knowledge, 50-70% (6-8) moderate knowledge and >70% (9-12) good knowledge.\u0000Results: Among the students with refractive errors, 82% had knowledge about their refractive error. Forty percent had myopia, 12% had astigmatism, 15 % had myopia and astigmatism, 10% had hyperopia, 5% had hyperopia and astigmatism. Among them 57.8% were not willing to undergo refractive surgery due to fear of complications. Forty eight percent had poor knowledge,43.1% had moderate and only 8.26% had a good knowledge of refractive surgeries. The majority preferred eyeglasses (82.6%) followed by both eyeglasses and contact lenses.\u0000Conclusion: Students had good awareness about refractive surgery but their familiarity and knowledge about it remained poor because of complications. An overwhelming majority of students still preferred spectacles as the method for vision correction.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"17 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140762262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immediate Effect of Intravitreal Bevacizumab Injection on Intraocular Pressure 玻璃体内注射贝伐单抗对眼压的即时影响

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1710

Kanwal Zareen, Abbasi, Ameera Jameel, Wajeeha Rasool, Bilal Humayun Mirza, Misbah Munshi

{"title":"Immediate Effect of Intravitreal Bevacizumab Injection on Intraocular Pressure","authors":"Kanwal Zareen, Abbasi, Ameera Jameel, Wajeeha Rasool, Bilal Humayun Mirza, Misbah Munshi","doi":"10.36351/pjo.v40i2.1710","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1710","url":null,"abstract":"Purpose: Raised intra ocular pressure following intravitreal Bevacizumabis a potential side effect which can be clinically significant. The aim of the study was to evaluate short term changes in intraocular pressure after intravitreal Bevacizumab injection.\u0000Study Design: Quasi experimental study.\u0000Place and Duration of Study: Benazir Bhutto Hospital, Rawalpindi from January 2021 to July 2021.\u0000Methods: This study includes 88 eyes of 88 patients who received intravitreal Bevacizumab injection. Both females and males between the ages of 10 and 80 years, with any indication for intravitreal Bevacizumab, were included. Intraocular pressure (IOP) was measured before injection, immediately after injection at 0 minutes, at 30 minutes and at 60 minutes. Paired t test was used to compare post injection changes in IOP from baseline.\u0000Results: All except one eye recoded increase in IOP immediately after injection. It returned to normal range in35 (39.8%) eyes at 30 minutes and at 60 minutes 78 (88.6%) eyes had normal IOP. Highest mean IOP was recorded immediately after injection which was 30.89+5.648and that reduced to 23.08+4.516 at 30 minutes and 18.14+2.623 at 60 minutes. Paired t test showed that the changes were significantly higher from baseline 13.30+2.78 at these intervals after injection.\u0000Conclusion: An increase in intraocular pressure after intravitreal Bevacizumab injection is a frequent occurrence; however, for the majority of patients, it is transient and returns to normal levels within one hour.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"185 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140788571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Intracameral Tissue Plasminogen (r-tPA) Activator in Resolution of Fibrinous Reaction in Refractory Toxic Anterior Segment Syndrome (TASS) 巩膜内组织浆蛋白酶（r-tPA）激活剂对缓解难治性中毒性前房综合征（TASS）纤维蛋白反应的效果

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1772

Bilal Khan, Adnan Ahmad, Javed Rasul

{"title":"Effectiveness of Intracameral Tissue Plasminogen (r-tPA) Activator in Resolution of Fibrinous Reaction in Refractory Toxic Anterior Segment Syndrome (TASS)","authors":"Bilal Khan, Adnan Ahmad, Javed Rasul","doi":"10.36351/pjo.v40i2.1772","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1772","url":null,"abstract":"Purpose: To evaluate the effectiveness of tissue plasminogen activator (r-tPA) in resistant toxic anterior segment syndrome (TASS) after Phacoemulsification.\u0000Study Design: Quasi experimental.\u0000Place and Duration of Study: Khyber Teaching Hospital, Peshawar from August 2021 to August 2023.\u0000Methods: Forty-six patients (46 eyes) with an anterior chamber fibrin reaction after cataract surgery were treated with intra-cameral injection of t-PA (30µg/0.1cc) following failure to respond to conventional treatment with intensive topical and subconjunctival steroids. Outcome measures were best corrected visual acuity (BCVA), clearance/recurrence of the fibrin reaction and complications.\u0000Results: Intra-cameral t-PA was injected2 to 6 weeks post Phacoemulsification in TASS cases. Mean post-operative injection time was 18.5± 10.2 days. After 1st day post injection, we observed total abolition of fibrinous exudate in 36(78.2%) cases and subtotal resolution in 10 (21.7%) cases. After 6 weeks the TASS was completely settled in 43(93.4%)cases. Mean BCVA improved from 0.59 ± 0.40 log MAR pre-injection to 0.38 ± 0.40 log MAR at 6th week post-injection (p=0.07). There was no statistically significant difference in BCVA and rate of fibrinolysis between the two groups after post r-tPA injections. Intra-cameral r-tPA was not associated with adverse effects like raised IOP or endophthalmitis.\u0000Conclusion: Intra-cameral t-PA injection (30µg/0.1cc)appears to be a safe and effective treatment option for resolving anterior chamber fibrin reaction refractory to conventional steroid therapy following cataract surgery.","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140763929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strabismus Measurements Using the Alternating and Simultaneous Prism Cover Tests 使用交替和同时棱镜遮盖试验进行斜视测量

Pakistan Journal of Ophthalmology Pub Date : 2024-04-01 DOI: 10.36351/pjo.v40i2.1763

Shua Azam

{"title":"Strabismus Measurements Using the Alternating and Simultaneous Prism Cover Tests","authors":"Shua Azam","doi":"10.36351/pjo.v40i2.1763","DOIUrl":"https://doi.org/10.36351/pjo.v40i2.1763","url":null,"abstract":"Purpose: Tocomparetheangleofdeviationbyperformingsimultaneousprismcover test (SPCT) and alternate prism cover test (APCT) at near (33cm) and far (6m).\u0000Study Design: Cross-sectional observational.\u0000Place and Duration of Study: Al-Ibrahim Eye Hospital, Karachi from July 2021 to December 2021.\u0000Methods: This study enrolled 32 participants diagnosed with constant esotropia, aged between 5 and 25 years, comprising 14 males and 18 females. Comprehensive ocular examinations for strabismus were performed, including simultaneous prism cover tests at both distance and near fixation, conducted with and without corrective glasses. Subsequently, an alternate prism cover test was administered at each fixation point, again both with and without glasses. Binocular single vision was evaluated using the Worth Four Dot test and the 10Δ test. Statistical analysis was conducted using SPSS version 20.0.\u0000Results: At distance fixation, the mean deviation angle measured by the simultaneous and alternate prism cover tests exhibited a significant difference of 9.78Δ (p=<.001). Similarly, at near fixation, the mean deviation angle between the simultaneous and alternate prism cover tests showed a significant difference of 10Δ (p=<.001).\u0000Conclusion: This study demonstrates a notable and statistically significant variance in the measured angle of deviation when employing different testing methodologies (SPCT and APCT).","PeriodicalId":169886,"journal":{"name":"Pakistan Journal of Ophthalmology","volume":"138 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140784567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0