Journal of Saudi Chemical Society最新文献

{"title":"Fabrication of Bi2O3/In2O3 p-n heterojunction with enhanced photocatalytic activity by efficient interfacial charge transfer","authors":"Qin Qin ,&nbsp;Tian Xiao ,&nbsp;Xiaodong Zhu","doi":"10.1016/j.jscs.2024.101919","DOIUrl":"10.1016/j.jscs.2024.101919","url":null,"abstract":"<div><p>Facilitating the separation of photogenerated charges is a crucial process in photocatalytic degradation of pollutants. In this study, Bi₂O₃/In₂O₃ composites were prepared using a co-precipitation method and subsequently calcined at 400 ℃ for 1 h. The Mott-Schottky curves confirmed a p(Bi₂O₃)-n(In₂O₃) heterojunction was yielded. Due to the significant difference in Fermi levels between Bi₂O₃ and In₂O₃, an internal electric field was established at the interface, with field lines directed from In₂O₃ to Bi₂O₃. Under illumination, the excited electrons accumulated in the conduction band (CB) of In₂O₃, while holes gathered in the valence band (VB) of Bi₂O₃, promoting charge separation and enhancing quantum efficiency. The composite material exhibited the highest photocatalytic activity when the atomic percentage of Bi to In was 1:1, with the first-order reaction rate constant of BI-1 increasing to 0.0149 min⁻¹, which is 4.3 and 4.4 multiples higher than that of pure In₂O₃ and pure Bi₂O₃. Recycling experiments demonstrated that the photocatalytic composite possesses good reusability and structural stability.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 5","pages":"Article 101919"},"PeriodicalIF":5.8,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1319610324001145/pdfft?md5=a6812a6dfdc54735aba5a0cc6589a639&pid=1-s2.0-S1319610324001145-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141953817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Removal of fluoride ions from wastewater via simple low-temperature thermal decomposition-modified phosphogypsum","authors":"Yonglin Wu ,&nbsp;Jianjun Chen ,&nbsp;Hongpan Liu ,&nbsp;Yonglan Zong ,&nbsp;Jilai Zhang ,&nbsp;Tianguo Li ,&nbsp;Youbo Su ,&nbsp;Ming Jiang","doi":"10.1016/j.jscs.2024.101921","DOIUrl":"10.1016/j.jscs.2024.101921","url":null,"abstract":"<div><p>Modified phosphogypsum (PG) was prepared via low-temperature thermal decomposition to remove fluoride ions from wastewater. This study discussed the effect of heat treatment (pyrolysis temperature and time) and operating conditions (initial fluoride ions concentration, dosage, solution temperature, and initial pH) on fluoride ions removal efficiency. The results showed that PG was most successful in removing fluoride at 140 ℃ for 5 h. At an initial fluoride ions concentration of 100 mg/L, a dosage of 10 g/L, a solution temperature of 20 ℃, and strongly acidic (pH=2) and neutral (pH=7) environments, the fluoride removal efficiency of the PG reached 93.9 % and 66.7 %, respectively. In addition, when the initial fluoride ion concentration was reduced (25 mg/L), the heat-treated modified PG exhibited inadequate fluoride removal (&lt;40 %). Increasing the solution temperature and initial pH was not conducive to fluoride ions removal. SEM-EDS, TG-DTG, FTIR, XRD and XPS analyses showed that thermal decomposition at a low temperature transformed the calcium sulfate dihydrate (CaSO₄·2H₂O) in the PG into calcium sulfate hemihydrate (CaSO₄·0.5H₂O) with higher solubility, increasing the Ca²⁺ ions concentration in the solution and further removing the F^- ions via chemical precipitation. Quantitative X-ray diffraction (QXRD) analysis revealed that the concentration of CaSO₄·0.5H₂O in PG is highest when subjected to optimal heat treatment conditions (140 ℃ for 5 h). Therefore, simple low-temperature thermal decomposition treatment (140 ℃) reduced PG energy consumption and effectively removed fluoride ions from wastewater, achieving the purpose of “ waste-treating-waste”.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 5","pages":"Article 101921"},"PeriodicalIF":5.8,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1319610324001169/pdfft?md5=075b3af24a9fc9a800f923498b0d5699&pid=1-s2.0-S1319610324001169-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141953818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silica supported Schiff-based palladium nanocatalyst for n-alkylation at room temperature","authors":"Shaheen M. Sarkar ,&nbsp;Md. Lutfor Rahman ,&nbsp;Kamrul Hasan ,&nbsp;Md. Maksudur Rahman Khan ,&nbsp;Mohammed Salim Akhter ,&nbsp;Emmet J. O’Reilly","doi":"10.1016/j.jscs.2024.101916","DOIUrl":"10.1016/j.jscs.2024.101916","url":null,"abstract":"<div><p>This works documents a new silica gel-supported nanocatalyst (<strong>Si@NSBPdNPs 3</strong>) with low Pd loadings for <em>n</em>-alkylation reactions at room temperature. Post synthesis characterisation using SEM-EDX and ICP techniques provided a quantitative assessment of palladium species. Additionally, TEM analysis unveiled an average palladium nanoparticle size of 5.87 ± 0.2 nm. In-depth X-ray Photoelectron Spectroscopy (XPS) analysis revealed its predominant composition as Pd(0) complexed to a Schiff base ligand on low cost silica matrix. The nanocatalyst exhibited high efficacy in the catalysis of <em>n</em>-alkylation (Michael addition) reactions with various <em>α,β</em>-unsaturated Michael acceptors, yielding the corresponding <em>n</em>-alkyl products at room temperature with exceptional yields. Notably, the catalyst exhibited good stability and could be easily separated from the reaction mixture. Moreover, the catalyst displayed recyclability potential, maintaining its original catalytic efficacy for up to seven cycles without any discernible loss.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 5","pages":"Article 101916"},"PeriodicalIF":5.8,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S131961032400111X/pdfft?md5=bd5cdf51d84e0ffe78eb01061f61f36f&pid=1-s2.0-S131961032400111X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141993449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modification of nickel foam with nickel phosphate catalyst layer via anodizing for boosting the electrocatalytic urea oxidation and hydrogen evolution reactions","authors":"Mohamed A. Ghanem,&nbsp;Abdullah M. Al-Mayouf,&nbsp;Mohamed O. Abdulkader,&nbsp;Khalaf A. Alfudhayli","doi":"10.1016/j.jscs.2024.101913","DOIUrl":"10.1016/j.jscs.2024.101913","url":null,"abstract":"<div><p>Urea oxidation reaction (UOR) and hydrogen evolution reaction (HER) are the key processes for implementing urinated water electrolysis and hydrogen green production, respectively. This contribution investigates the modification of commercial nickel foam (NF) with a nickel phosphate (NiPO/NF) heterostructure layer via anodizing in phosphate solution at various potentials (5, 10 and 15 V) as a simple and efficient route to boost the urea-assisted water electrolysis and hydrogen production in alkaline medium. The morphology and composition physicochemical characterisation of the phosphate layer exhibit aggregates of crystalline nanoparticles with interstitial mesoporous and macroporous networks with a mole composition ratio of 9.42: 1.0: 8.14 for Ni: P: O respectively. The electrochemical measurements revealed the NiPO/NF anodized at 10 V exhibits a superior electroactive surface area of 255 cm², a substantially higher urea oxidation current compared to pristine NF, achieving 20 and 500 mA/cm² at 1.35 and 1.6 V vs. RHE respectively and retained 100 % of activity during the urea electrolysis for more than 3 h. The electrochemical impedance analysis confirmed the alkaline urea oxidation reaction proceeded via indirect (EC) and direct mechanism and the CO₂ intermediates adsorption–desorption became the predominant reaction at more positive potential. The NiPO/NF anode employed in an H-shape can deliver up to ±400 mA/cm² for UOR/HER at a bias potential of 1.85 V and 8-fold (2.0 mmol/min) much higher hydrogen production rate compared to the pristine NF anode (0.25 mmol/min). Combining commercial nickel foam modification via anodizing and alkaline urea electrolysis at ambient conditions offers a unique and innovative solution for both large-scale hydrogen green production as well as remedy of the urinated wastewater for a more sustainable future.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 5","pages":"Article 101913"},"PeriodicalIF":5.8,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S131961032400108X/pdfft?md5=1bd07d969e0bdd8d9088be4f4a1c555e&pid=1-s2.0-S131961032400108X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141881312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infra-red assistance for durable multi-functional silk by in-situ clustering of nanopalladium: Antimicrobial, UV protection and self-cleaning","authors":"Omar M. Alatawi","doi":"10.1016/j.jscs.2024.101914","DOIUrl":"10.1016/j.jscs.2024.101914","url":null,"abstract":"<div><p>Herein, durable multi-functional silk is successfully prepared via in-situ clustering of nanopalladium, under the assistance of infrared irradiation. Whereas, the produced fabric acquired superior antimicrobial, UV-resistance and self-cleaning potentialities. Different instrumental analyses were performed, to reveal that; size average of nanopalladium was ranged in 8.6–21.4 nm. Additionally, increment in the nanopalladium concentration reflected in observable improvement of the mechanical properties, color strength and thermal stability. Yellowish degree was significantly increased from 22.36 for silk finished with 100 ppm of nanopalladium (silk-Pd-1) to 42.52 for silk finished with 300 ppm of nanopalladium (silk-Pd-3). Functional treatment of silk with higher concentrated nanopalladium exhibited the highest microbicide action even after 5 washing cycles, the microbial reduction percentage was evaluated to be 67 %, 65 % &amp; 70 % against <em>“St. Aureus</em>, <em>E. Coli</em> and <em>C. Albicans”</em>, respectively. Ultraviolet protective factor (UPF) was superiorly evaluated for silk-Pd-3 to be 98.1 and 40.4 before and after 5 washing cycles. The aid of nanopalladium for acquiring the prepared silk the self-cleaning property as add-function was approved via kinetic study to show that the prepared fabrics exhibited good self-cleaning character by successive in-clustering of nanopalladium, while, t_1/2 for dirt removal was 190.9 min.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 5","pages":"Article 101914"},"PeriodicalIF":5.8,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1319610324001091/pdfft?md5=16cdc139a2a24a9982b971b4b8b1dd00&pid=1-s2.0-S1319610324001091-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141941957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Furo[3,2-b]pyridine: Chemical synthesis, transformations and biological applications","authors":"Sumayya Akram ,&nbsp;Sana Aslam ,&nbsp;Nasir Rasool ,&nbsp;Matloob Ahmad ,&nbsp;Sami A. Al-Hussain ,&nbsp;Magdi E.A. Zaki","doi":"10.1016/j.jscs.2024.101906","DOIUrl":"10.1016/j.jscs.2024.101906","url":null,"abstract":"<div><p>The combination of heterocycles renders a new possibility to synthesize multicyclic compounds having improved biological activities. Furo[3,2-<em>b</em>]pyridine is a fused heterocyclic ring system comprising a furan ring attached at the third and second positions of pyridine. These heterocyclic compounds can be easily synthesized from versatile starting materials including pyridine, furan, benzofuran, and benzopyridine <em>via</em> cycloaddition, cycloisomerization, multicomponent, cross-coupling, and Dakin-type reactions by utilizing microwave, copper, and palladium based catalysts. Among the chemical transformations of furo[3,2-<em>b</em>]pyridine derivatives, the review covered acetylation, addition, condensation, chlorination, Suzuki coupling, Vilsmeier-Haack reaction, and nucleophilic substitution reactions. Furo[3,2-<em>b</em>]pyridine has attracted remarkable attention from researchers due to its wide range of pharmacological and biological applications as antibiotic, antiviral, antifungal, anticancer, inhibitors of nicotinic acetylcholine receptors, CLKs, e1F4A, DYRKIA, <em>α</em>-glucosidase and <em>β</em>-glucosidase. The purpose of the review is to discuss the chemistry of the title reported during 2019–2024.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 5","pages":"Article 101906"},"PeriodicalIF":5.8,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1319610324001017/pdfft?md5=abd270b9f981be9d06a54b65ff4320e3&pid=1-s2.0-S1319610324001017-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141844985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isatin-based ibuprofen and mefenamic acid Schiff base derivatives as dual inhibitors against urease and α–glucosidase: In vitro, in silico and cytotoxicity studies","authors":"Saima Daud ,&nbsp;Obaid‐ur‐Rahman Abid ,&nbsp;Malik Saadullah ,&nbsp;M. Fakhar-e-Alam ,&nbsp;Simone Carradori ,&nbsp;Asma Sardar ,&nbsp;Basit Niaz ,&nbsp;M. Atif ,&nbsp;Susi Zara ,&nbsp;Muhammad Rashad","doi":"10.1016/j.jscs.2024.101905","DOIUrl":"10.1016/j.jscs.2024.101905","url":null,"abstract":"<div><p>α-Glucosidase and urease inhibitors have emerged as crucial for developing therapeutic drugs targeting diabetes and gastrointestinal disorders. This study reports on new series of ibuprofen and mefenamic acid Schiff base derivatives incorporating isatin as dual inhibitors of α-glucosidase and urease enzymes. These synthesized derivatives (7a-r) were structurally characterized by ¹H NMR, ¹³C NMR and HRMS (EI). Biological evaluation (IC₅₀) identified several derivatives <em>i.e.,</em> <strong>7a</strong> (urease = 17.37 ± 1.37 µM, α-glucosidase = 44.1 ± 1.15 µM), <strong>7j</strong>, (urease = 16.61 ± 1.37 µM, α-glucosidase = 81.2 ± 1.33 µM), <strong>7o</strong>, (urease = 18.63 ± 1.27 µM, α-glucosidase = 70.3 ± 1.14 µM), <strong>7r</strong> (urease = 11.36 ± 1.32 µM, α-glucosidase = 39.3 ± 1.17 µM), as dual inhibitors of urease (thiourea 21.37 ± 1.76 µM) and α–glucosidase (acarbose 375.82 ± 1.76 µM) enzymes. These bioactive derivatives were explored for cell viability studies against mononuclear cells revealing a good cytocompatibility. <em>In silico</em> molecular docking studies were also conducted to predict the binding mode of new derivatives with target enzymes that were found consistent with the results of <em>in vitro</em> research.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 5","pages":"Article 101905"},"PeriodicalIF":5.8,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1319610324001005/pdfft?md5=952b67fae9df2f4ffe01394e8a08bf6d&pid=1-s2.0-S1319610324001005-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141702089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical performance of cauliflower like binder-free magnesium-sulphide-electrodes for supercapacitor application","authors":"Sadaf Atta ,&nbsp;A. Rasheed ,&nbsp;A. Farid ,&nbsp;Misbah Yousaf ,&nbsp;A. Raza ,&nbsp;I.A. Khan ,&nbsp;Mohamed A. Ghanem ,&nbsp;Frank Marken","doi":"10.1016/j.jscs.2024.101904","DOIUrl":"10.1016/j.jscs.2024.101904","url":null,"abstract":"<div><p>Herein, magnesium sulphide (MgS) electrode material (EM) is deposited on nickel-foam (NF) placed at 16 and 17 cm away from the raw material by simple powder vapour transport method. The increasing source to substrate distance (SSD) not only changed the structural parameters but also changed the nanofibers to cauliflowers like surface morphology. The cauliflowers like MgS/NF EM exhibited high specific capacitance (6339 F/g) as compared to the specific capacitance (1677 F/g) of nanofibers like MgS/NF EM. The cauliflowers like EM is showed high energy density of 220–99 Wh/kg, power density of 250–2500 W/kg, equivalent series resistance of 0.95 O and capacitance-stability of 93 % even for 10,000 cycles. The increasing SSD is fruitful for the increment in diffusion rate as confirmed by shifting of electrochemical impedance spectrum to y-axis, Dunn’s model and power law simulations. The diffusive contribution is 88/82 % at 5 mV/s which become 63/50 % at 100 mV/s for the cauliflower/nanofibers like EM. Moreover, the cauliflowers like EM have both battery and capacitive nature as 0.5 &lt; b &lt; 1 predicted by power law simulations. Additionally, the configured asymmetric supercapacitive (ASC) device is presented the specific capacitance of 834 F/g, energy density of 354–247 Wh/kg and power density of 2625–26250 W/kg. The ASC device could maintain the Coulombic-efficiency of 99 % and capacitance stability of 93 % even for 10,000 cycles. The excellent pseudocapacitive behaviour of MgS/NF EM enables them to use in the lithium ion battery and supercapacitor devices.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 5","pages":"Article 101904"},"PeriodicalIF":5.8,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1319610324000991/pdfft?md5=e084a1bfd44c1df6e507c252452be879&pid=1-s2.0-S1319610324000991-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, characterization, and molecular docking studies of novel hippuric acid anhydrides as potential antiurolithic, analgesic and free radical scavenging agents","authors":"Zahid Munawar ,&nbsp;Kashif ur Rehman Khan ,&nbsp;Humaira Nadeem ,&nbsp;Saeed Ahmad ,&nbsp;M Yasmin Begum ,&nbsp;Ayesha Siddiqua ,&nbsp;Huma Rao ,&nbsp;Muhammad Tariq Khan","doi":"10.1016/j.jscs.2024.101902","DOIUrl":"10.1016/j.jscs.2024.101902","url":null,"abstract":"<div><p>Hippuric acid is a biotransformation product in humans which is excreted through urine. Dietary intake of phenolic compounds increases its concentration in urine. Hippuric acid is experimentally proved to be a regulator of calcium oxalate super saturation in human urine and has a solvent effect on oxalate salts. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used analgesics employed in associated renal colic of urolithiasis. The objective of the present study was to chemically link hippuric acid through anhydride linkage to various NSAIDs to synthesize potential mutual prodrugs for urolithiasis and associated renal colic. Hippuric acid was linked to eleven NSAIDs through anhydride linkage by first synthesizing hippuryl chloride using oxalyl chloride as chlorinating agent, followed by its reaction with sodium salts of NSAIDs. Structures of obtained compounds were elucidated using UV spectrophotometry, FTIR spectrometry, 1H NMR and C-13 NMR spectrometry. Synthesized compounds were evaluated for <em>in vitro</em> antioxidant, <em>in vivo</em> acute toxicity, <em>in vivo</em> antiurolithic, <em>in vivo</em> analgesic and <em>in vitro</em> hydrolysis studies. Molecular docking analysis on TNF-α and COX-2 was carried out to determine target protein binding. Synthesized compounds showed stability at acidic pH which indicate potential gastro protective effect of synthesized conjugates. Compounds P9 an P6 showed maximum <em>in vivo</em> antiurolithic activity while P9 and P8 showed maximum <em>in vitro</em> antioxidant activity. All the conjugates except P2 showed significant analgesic activity which show that conjugation of hippuric acid to NSAIDs did not result in loss of analgesic potential. Docking studies showed better affinity with TNF-α as compared to COX-2.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 5","pages":"Article 101902"},"PeriodicalIF":5.8,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1319610324000978/pdfft?md5=2502a67c42378a90f69d9bfeec915db3&pid=1-s2.0-S1319610324000978-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141704968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Greenly engineered bimetallic Ag-ZnO nanohybrids for synergistic antibacterial enhancement","authors":"Hayfa Habes Almutairi","doi":"10.1016/j.jscs.2024.101899","DOIUrl":"https://doi.org/10.1016/j.jscs.2024.101899","url":null,"abstract":"<div><p>The escalating issue of infectious agents developing resistance to traditional antibiotics has spurred ongoing research into effective and broad-spectrum antimicrobial solutions. This study focuses on the fabrication of silver-zinc oxide Nanohybrids (A-ZnO-NHs) with varying silver content (1 %, 3 %, 5 %) using a simplified modified sol–gel method, further enhanced by a green synthesis approach utilizing orange peel extract for the generation of silver nanoparticles. The physicochemical characteristics of the A-ZnO-NCs were thoroughly examined. X-ray diffraction analysis verified the presence of Ag nanoparticles within the zinc oxide and scanning electron microscopy revealed the nanoscale silver particles uniformly distributed on the spherical zinc oxide nanoparticles. Transmission electron microscopy indicated that the Ag-ZnO-NCHs ranged in size from 10 to 20 nm. X-ray photoelectron spectroscopy analysis confirmed the formation of strong chemical bonds between the silver and zinc oxide surfaces in the nanohybrids. This study explored into the structural, morphological, and antimicrobial characteristics of the A-ZnO-NHs at different compositions. The bactericidal efficiency of the A-ZnO-NHs was assessed against both gram-positive and gram-negative bacterial strains. The impact of the A-ZnO-NHs on the cellular structure and chemical composition of Staphylococcus aureus (<em>S. aureus</em>) and Escherichia coli (<em>E. coli</em>) was also explored. The findings revealed that the A-ZnO-NHs with 3 % silver content demonstrated higher antimicrobial activity against <em>E. coli</em> and <em>S. aureus</em> compared to other compositions and pure zinc oxide nanoparticles. The antimicrobial activity decreases when the concentration of silver increases because the silver particles agglomerate together, reducing their surface area and lessening their effectiveness as antibacterial agents, despite their potential for various applications.</p></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 4","pages":"Article 101899"},"PeriodicalIF":5.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1319610324000942/pdfft?md5=67dba82fc90267dc28ee98d2c69879b7&pid=1-s2.0-S1319610324000942-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}