Journal of Pharmacy and Nutrition Sciences最新文献_第8页

GCTOF-MS and HPLC Identification of Phenolic Compounds with Different Fractional Extracts of Lepironia articulata 气相色谱-质谱-高效液相色谱法鉴定白头翁不同部位提取物中酚类化合物的含量

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.01.1

R. Othman, R. Ramya, N. Hassan, Suhair Kammona

{"title":"GCTOF-MS and HPLC Identification of Phenolic Compounds with Different Fractional Extracts of Lepironia articulata","authors":"R. Othman, R. Ramya, N. Hassan, Suhair Kammona","doi":"10.29169/1927-5951.2020.10.01.1","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.01.1","url":null,"abstract":"Cyperaceae species have an intrinsic value as a source of active elements with biological activity from the \u0000family of monocotyledonous known as sedges. Sedges grow in all types of soils associated with wetlands or poor soils. The aim of this present study is to evaluate the content of phenolic compounds by qualitative and quantitive analysis on Lepironia articulata. Dried leaves of L. articulata were successfully extracted by using water extraction then separated with different solvent polarities; petroleum ether, ethyl acetate and butanol fractions before being analysed using GCTOF-MS, microplate reader and HPLC. The result from the GCTOF-MS analysis of fractional extracts showed that 48 compounds were found in petroleum ether, ethyl acetate and butanol extracts. From those extracts, only six phenolic compounds were identified in ethyl acetate and butanol extracts which were 2-Methoxy-4-vinylphenol, Phenol, 2,4- \u0000bis(1,1-dimethylethyl)-, 4-Hydroxybenzaldehyde, Catechol, Phenol, 2-methoxy- and Vanillin. The total phenolic content \u0000was found to be 984.63 ± 5.96 μg GAE/g DW in L. articulata. Quantitative analysis of individual phenolic acid by HPLC \u0000showed the predominant amount of Vanillic acid (0.48 ± 0.00 μg/g DW) in ethyl acetate while 4-Hydroxybenzoic acid and \u0000Caffeic acid, both of which were 0.12 ± 0.00 μg/g DW in butanol extracts. In the present study, the plant extracts \u0000demonstrated the highest phenolic compound detected in ethyl acetate and butanol.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"13 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89260135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Review of Medicinal uses, Phytochemistry and Biological Activities of Antidesma laciniatum and A. membranaceum - 乳突抗丝马和膜草的药用、植物化学和生物活性研究进展

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.05.11

A. Maroyi

{"title":"Review of Medicinal uses, Phytochemistry and Biological Activities of Antidesma laciniatum and A. membranaceum -","authors":"A. Maroyi","doi":"10.29169/1927-5951.2020.10.05.11","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.05.11","url":null,"abstract":"Antidesma laciniatum and A. membranaceum are small trees used as traditional medicines in tropical Africa. This extensive literature review synthesizes the information currently available on the medicinal uses, phytochemistry and biological activities of A. laciniatum and A. membranaceum. The university library and electronic search engines such as Google Scholar, Scopus, Web of Science, ScienceDirect, and PubMed were searched for pertinent information on the medicinal uses, phytochemistry, and biological activities of A. laciniatum and A. membranaceum. Traditionally, the species have been used as aphrodisiac, and traditional medicine for cough, kwashiorkor, mouth ulcers, pneumonia, prevent miscarriage, snakebites, stomachache and wounds. Various phytochemicals such as essential oils, isoflavonoid glycosides, phytosterols, benzopyranones, lignin glucosides, megastigmane, phenolics, steroids, squalene, terpenoids, triterpenoids, and tetrahydroisoquinoline alkaloids have been isolated from A. laciniatum and A. membranaceum. In vitro studies have confirmed the biological activities of A. laciniatum and A. membranaceum which, include antimicrobial, antioxidant, antiplasmodial, antitrypanosomal, leishmanicidal, molluscicidal and cytotoxicity activities. More pharmacological studies including phytochemical, toxicological, in vitro and in vivo experiments are needed to provide evidence for the clinical effectiveness of remedies prepared from the species.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"22 1","pages":"257-263"},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81653435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Synthesis and Review of Medicinal Uses, Phytochemistry and Pharmacological Properties of Cissampelos mucronata A. Rich. (Menispermaceae) 山参的合成、药用、植物化学及药理研究进展。(防己科)

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.05.6

Alfred Maroyi

{"title":"A Synthesis and Review of Medicinal Uses, Phytochemistry and Pharmacological Properties of Cissampelos mucronata A. Rich. (Menispermaceae)","authors":"Alfred Maroyi","doi":"10.29169/1927-5951.2020.10.05.6","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.05.6","url":null,"abstract":"Cissampelos mucronata A. Rich. is a perennial climber widely used as traditional medicine in tropical Africa. This study is aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of C. mucronata. Documented information on medicinal uses, phytochemical and pharmacological properties of C. mucronata was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the University library. The articles published between 1962 and 2020 were used in this study. This study revealed that leaves, rhizome, roots and stems, and whole plant parts of C. mucronata are mainly used as traditional medicines for sexually transmitted infections, fever, swellings, headache, respiratory problems, snakebite, malaria, pregnancy problems and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, anthraquinones, flavonoids, glycerine, glycosides, phenolics, reducing sugars, resin, saponins, steroids, tannins and triterpenes. Pharmacological research revealed that C. mucronata extracts and alkaloids isolated from the species have antibacterial, anti-mycobacterial, antifungal, antiplasmodial, antitrypanosomal, anti-ulcer, anti-androgenic, anti-steroidogenic, enzyme tyrosine kinase p56 inhibitory, hypoglycemic, larvicidal, molluscicidal, sedative, tocolytic, uterine relaxant and cytotoxicity activities. There is need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since C. mucronata contains potentially toxic compounds","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81718577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Review of Medicinal Uses, Phytochemistry and Biological Activities of Bolusanthus speciosus (Bolus) Harms (Fabaceae) 花椒科花椒药用、植物化学及生物活性研究进展

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.05.9

Alfred Maroyi

{"title":"A Review of Medicinal Uses, Phytochemistry and Biological Activities of Bolusanthus speciosus (Bolus) Harms (Fabaceae)","authors":"Alfred Maroyi","doi":"10.29169/1927-5951.2020.10.05.9","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.05.9","url":null,"abstract":"Bolusanthus speciosus (Bolus) Harms is a deciduous and ornamental tree with its different parts used traditionally to treat various diseases. The main aim of this review is to provide an overview and critical analysis of the medicinal uses, phytochemistry, and biological activities of B. speciosus. The information presented in this study was gathered using various databases such as PubMed, Taylor and Francis imprints, Springer, NCBI, Google scholar and Science direct, and review of books, journal articles and other scientific publications kept in the university library. The articles published between 1933 and 2020 were used in this study. The bark, leaf and stem infusion of B. speciosus are mainly used for cleansing blood and as an emetic, and a traditional medicine for abdominal pains, kidney problems, sexually transmitted infections and stomach problems. Phytochemical compounds identified from the leaves, root bark, root wood, seeds and stem bark of B. speciosus include alkaloids, essential oils, flavonoids, phenolics, saponins and tannins. The biological activities exhibited by B. speciosus and the phytochemical compounds isolated from the species include anti-arthritic, antibacterial, antigonococcal, antimycobacterial, antifungal, anti-HIV, anti-inflammatory and antioxidant activities. Future research should focus on toxicological screening, in vivo studies and clinical trials involving the crude extracts and phytochemical compounds isolated from the species.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"102 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73100310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of Salicylic Acid on Carotenoids and Chlorophyll Content in Mas Cotek (Ficus deltoidea Jack var. trengganuensis) Leaves and its Retinol Activity Equivalents (RAE) 水杨酸对郑加榕叶片类胡萝卜素和叶绿素含量及其视黄醇活性当量的影响

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.01.5

A. Ismail, N. Shahidan, N. Mat, Rashid M. Othman

{"title":"Effect of Salicylic Acid on Carotenoids and Chlorophyll Content in Mas Cotek (Ficus deltoidea Jack var. trengganuensis) Leaves and its Retinol Activity Equivalents (RAE)","authors":"A. Ismail, N. Shahidan, N. Mat, Rashid M. Othman","doi":"10.29169/1927-5951.2020.10.01.5","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.01.5","url":null,"abstract":"This study was conducted to determine the effect of different concentrations of salicylic acid (SA) (control, 0.01, 0.10, 1.00 mM) on carotenoids and chlorophyll content and its retinol activity equivalents (RAE) value in Ficus deltoidea Jack var. trengganuensis leaves. In this study, 12 seedlings of Ficus deltoidea Jack var. trengganuensis were sprayed with different concentrations of SA. Carotenoid content was determined using High-Performance Liquid Chromatography (HPLC) and chlorophyll content was determined using chlorophyll meter. Retinol activity equivalents were calculated using RAE formulation. From the results obtained, two types of carotenoids, lutein and β-carotene, were detected in HPLC. The highest lutein and β-carotene content present in Ficus deltoidea Jack var. trengganuensis leaves extract was found in 0.10 mM SA treatment (93.50 ± 0.71 μg/g DW) for lutein and (282.00 ± 46.67 μg/g DW) for βcarotene, while the lowest lutein compound was found in 1.00 mM SA treatment (30.25 ± 1.77 μg/g DW) while the least β-carotenoid content was found in (1.00 mM SA) treatment (63.00 ± 0.71 μg/g DW). The same goes for retinol activity equivalents, the highest retinol activity equivalents was recorded in 0.10 mM SA treatment while lowest in 1.00 mM SA treatment. For chlorophyll content, the highest reading was showed in 0.10 mM SA treatment (73.50 ± 0.71 μg/g DW) while the lowest reading was in 1.00mM SA treatment (42.10 ± 1.41 μg/g DW). From this study, it can be concluded that salicylic acid at a certain concentration could increase or improve the carotenoid or chlorophyll content. Thus, it could be an alternative source of carotenoid and chlorophyll for the food and pharmaceutical industry in the future.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"12 1","pages":"25-33"},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87984441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Centrapalus pauciflorus: Review of its Medicinal uses, Phytochemistry and Pharmacological Properties - 少花参:药用、植物化学及药理研究进展

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.05.15

Alfred Maroyi

{"title":"Centrapalus pauciflorus: Review of its Medicinal uses, Phytochemistry and Pharmacological Properties -","authors":"Alfred Maroyi","doi":"10.29169/1927-5951.2020.10.05.15","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.05.15","url":null,"abstract":"Centrapalus pauciflorus is a herbaceous plant that is used as a traditional medicine and a source of epoxidised oil. This study is aimed at providing a critical review of the pharmacological properties, phytochemistry and medicinal uses of C. pauciflorus. Documented information on the pharmacological properties, phytochemistry and medicinal uses of C. pauciflorus was collected from several online sources, which included Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, these, books, dissertations, book chapters and journal articles. This study showed that the leaves and epoxidised oil of C. pauciflorus are used as traditional medicines for external injury, wounds, diabetes, chest pains, eye infections, stomach problems and skin infections. Phytochemical compounds identified from the species include coumarins, essential oils, fatty acids, flavonol glycosides, phenolic acids, sterols, sesquiterpene lactones, triterpenoids, alkaloids, cardiac glycosides, carotenoids, flavonoids, polyuronoids, saponins, steroids, tannins and terpenoids. Pharmacological research revealed that C. pauciflorus extracts and compounds isolated from the species have analgesic, anti-dermatitis, antimicrobial, antiulcerogenic, hypoglycemic, insecticide, larvicidal and sedative activities. Centrapalus pauciflorus should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84308084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Evaluation of Medicinal uses, Phytochemistry and Biological Activities of Adenia gummifera (Harv.) Harms - 甘树腺(Adenia gummifera)药用价值、植物化学及生物活性评价伤害,

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.05.14

Alfred Maroyi

{"title":"Evaluation of Medicinal uses, Phytochemistry and Biological Activities of Adenia gummifera (Harv.) Harms -","authors":"Alfred Maroyi","doi":"10.29169/1927-5951.2020.10.05.14","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.05.14","url":null,"abstract":"Adenia gummifera (Harv.) Harms is a climber or liane widely used as traditional medicine throughout its distributional range in tropical Africa. Adenia gummifera occurs naturally in the Democratic Republic of Congo (DRC), Eswatini, Ethiopia, Kenya, Malawi, Mozambique, Seychelles, Somalia, South Africa, Tanzania, Uganda, Zambia and Zimbabwe. This study is aimed at providing a critical review of the medicinal uses, phytochemistry and biological activities of A. gummifera. Documented information on the medicinal uses, phytochemistry and biological activities of A. gummifera was collected from several online sources, which included Scopus, Google Scholar, PubMed and Science Direct. Additional information was gathered from pre-electronic sources such as book chapters, books, journal articles and scientific publications sourced from the university library. This study showed that the species is widely used as an emetic and a protective charm, and, as traditional medicine for infertility, sexually transmitted infections, gastro-intestinal infections, leprosy, respiratory infections, malaria and menstrual problems. Phytochemical compounds identified from the species include polyacetylenic diepoxide, alkaloids, flavonoids, flavonol, modeccin, proanthocyanidins, tetraphyllin, phenolics, polyphenol and tannins. Pharmacological research revealed that A. gummifera extracts and compounds isolated from the species have antibacterial, antifungal, acetylcholinesterase inhibitory (AChEI), anaesthetic, antioxidant, antiplasmodial and cytotoxicity activities. Future research on A. gummifera should focus on detailed phytochemical evaluations including toxicological, in vivo and clinical studies to corroborate the traditional medical applications of the species.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78689884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Baccharoides lasiopus: Review of its Medicinal uses, Phytochemistry and Pharmacological Properties - 棘棘草:药用、植物化学和药理性质综述

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.05.5

Alfred Maroyi

{"title":"Baccharoides lasiopus: Review of its Medicinal uses, Phytochemistry and Pharmacological Properties -","authors":"Alfred Maroyi","doi":"10.29169/1927-5951.2020.10.05.5","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.05.5","url":null,"abstract":"Baccharoides lasiopus is a woody shrub widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of the pharmacological properties, phytochemistry, and medicinal uses of B. lasiopus. Documented information on the pharmacological properties, phytochemistry, and medicinal uses of B. lasiopus was collected from several online sources, which included Scopus, Google Scholar, PubMed and Science, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. The articles published between 1971 and 2020 were used in this study. This study showed that the leaves, roots, stems, whole plant parts, root and stem bark of B. lasiopus are widely used as galactagogue, purgative and anthelmintic, and traditional medicine for headache, liver diseases, skin diseases, respiratory infections, malaria, augment labour, convulsions, epilepsy, fainting, female reproductive problems, and gastro-intestinal problems. Phytochemical compounds identified from the species include elemanolide type sesquiterpene lactones, alkaloids, anthraquinones, cardiac glycosides, coumarins, flavonoids, phenolics, reducing sugars, saponins, steroids, tannins, terpenoids, and xanthines. Pharmacological research revealed that B. lasiopus extracts and compounds isolated from the species have anthelmintic, antibacterial, antifungal, antiviral, antihyperglycemic, antiplasmodial, antimalarial, antiprotozoal, haematological, hepatoprotective, hepatotoxicity, larvicidal, and cytotoxicity activities. Future research on B. lasiopus should focus on the possible biochemical mechanisms of action of both the crude extracts and identified phytochemical compounds including toxicological, in vivo, and clinical studies to corroborate the traditional medical applications of the species.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79587893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Evaluation of Chemical Properties, Biological Activities and Ethnomedicinal uses of Cladostemon kirkii - 藿香的化学性质、生物活性及民族药用价值评价

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.05.3

Alfred Maroyi

{"title":"Evaluation of Chemical Properties, Biological Activities and Ethnomedicinal uses of Cladostemon kirkii -","authors":"Alfred Maroyi","doi":"10.29169/1927-5951.2020.10.05.3","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.05.3","url":null,"abstract":"Cladostemon kirkii (Oliv.) Pax & Gilg is a shrub or a small tree widely used as traditional medicine in tropical Africa. This study is aimed at evaluating the chemical properties, biological activities and ethnomedicinal uses of C. kirkii. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The articles published between 1960 and 2019 were used in this study. This study revealed that the bark, leaf, root and stem infusion and/or decoction of C. kirkii are mainly used as traditional medicines for boils, colds, gastro-intestinal problems, hypertension, ophthalmia, rheumatism, sexual dysfunction, abdominal pains, sexually transmitted infections, sores and wounds. Phytochemical compounds identified from the species include mearnsitrin, myricitrin, kaempferol-5-rhamnoside, kaempferin, kaempferol 3-gluco-7-rhamnoside, quercetin 3,7-dirhamnoside, quercetin 3-gluco-7-rhamnoside, choline, 3-hydroxyprolinebetaine and tetramethylammonium. Cladostemon kirkii should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72883226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of Carotenoids Content and Composition of Saffron from Different Localities 不同产地藏红花类胡萝卜素含量及成分的研究

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-01-05 DOI: 10.29169/1927-5951.2020.10.01.6

R. Othman, F. Hatta, N. Hassan, Suhair Kammona

{"title":"Characterization of Carotenoids Content and Composition of Saffron from Different Localities","authors":"R. Othman, F. Hatta, N. Hassan, Suhair Kammona","doi":"10.29169/1927-5951.2020.10.01.6","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.01.6","url":null,"abstract":"The most essential carotenoids for humans are found in plants that are normally yellow, orange, and red \u0000coloured pigments. They are typically and mostly lipophilic in nature, but some unique plant species may yield watersoluble carotenoids. Saffron or Crocus sativus contains hydrophilic carotenoids named crocin. Thus, this paper will \u0000describe the extraction and characterization of hydrophilic and lipophilic carotenoids (colour properties) obtained from \u0000saffrons of different geographical origins. They are specifically the Iranian, Turkish, and Kashmiri saffron respectively. Maceration techniques have been employed to extract the targeted compounds, whereas the characterization of the compounds has been analysed using HPLC. The extraction and characterization of carotenoids in saffron from different geographical origins found that the amount of crocin content was substantially higher in Iranian saffron, which was 11414.67 ± 516.34 μg/g DW followed by Turkish and Kashmiri saffron. Lipohilic carotenoids (i.e. crocetin, β-carotene, and zeaxanthin) were detectable in Iranian and Turkish saffron but absent in Kashmiri saffron. Similarly, the highest amount of crocetin content was found in Iranian saffron at 1054.73 ± 50.31 μg/g DW, while the highest amount of β-carotene and zeaxanthin was found in Turkish saffron at 512.92 ± 79.98 μg/g DW and 252.04 ± 60.34 μg/g DW, respectively. There was a marked difference in carotenoid composition sourced from different localities. Various environmental factors like climatic conditions, agricultural practices, stigma separation, and storing and drying processes may play an important role to explain such difference","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"11 1","pages":"34-40"},"PeriodicalIF":0.0,"publicationDate":"2020-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80148263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3