Journal of Pharmacy and Nutrition Sciences最新文献_第6页

Current Trends in the Treatment of Human Epidermal Growth Factor Receptor-2 Negative Breast Cancer 人表皮生长因子受体-2阴性乳腺癌的治疗现状

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-07-25 DOI: 10.29169/1927-5951.2020.10.04.5

P. Sivanandy

{"title":"Current Trends in the Treatment of Human Epidermal Growth Factor Receptor-2 Negative Breast Cancer","authors":"P. Sivanandy","doi":"10.29169/1927-5951.2020.10.04.5","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.04.5","url":null,"abstract":"Breast cancer affect almost 1 in 8 women and it is highest in developed and developing countries. There are many drugs exist for the treatment of breast cancer, but still the incidence of mortality and morbidity are high among all cancer types in most countries. Even though the conventional therapies play a major role in the management of breast cancer, its complications are obvious and unavoidable. The newer targeted drug therapy came in place to reduce complications in some extent, but not fully. Hence, a review was aimed to analyse the efficacy and safety of newer anticancer drugs that approved for the treatment of breast cancer by US-FDA from 2017 to 2019. The Olaparib, Talazoparib, and Ribociclib are the newly approved drugs for the treatment of breast cancer during this review period. Among these new drugs, Olaparib and Talazoparib alone or in combination with other anticancer drugs considered as safe and efficacious. Patients with Olaparib or Talazoparib as monotherapy have median progression-free survival of 2.8 to 8.6 months longer and has 42-46% lower risk of death (P<0.001). A combination of conventional therapies and nonpharmacological approach are warranted for the best benefit of cancer patients and to improve their quality of life.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82829833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Parenteral Nutrition-Associated Factors on the Growth of Premature Infants 肠外营养相关因素对早产儿生长发育的影响

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-07-25 DOI: 10.29169/1927-5951.2020.10.04.2

K. Tongiew

引用次数: 0

In Vitro Dissolution Interference Study in Presence of Paracetamol Tablets with Freshly Prepared Mango Juices on Simulated Gastrointestinal Digestion 新鲜芒果汁对扑热息痛片体外模拟胃肠消化溶出干扰研究

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-07-25 DOI: 10.29169/1927-5951.2020.10.04.4

Md. Didaruzzaman Sohel

引用次数: 0

A Review of Medicinal Uses, Phytochemistry and Biological Activities of Markhamia tomentosa 毛毛Markhamia tomentosa的药用、植物化学和生物活性研究进展

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-07-25 DOI: 10.29169/1927-5951.2020.10.04.3

A. Maroyi

引用次数: 1

Detecting Biogenic Amines in Food and Drug Plants with HPLC: Medical and Nutritional Implications 高效液相色谱法检测食品和药用植物中的生物胺:医学和营养意义

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-05-12 DOI: 10.29169/1927-5951.2020.10.03.2

A. Oleskin

引用次数: 7

Impact of Dietary Patterns and Nutritional Status on the Academic Performance of Omani School Students 膳食模式和营养状况对阿曼学生学业成绩的影响

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-05-12 DOI: 10.29169/1927-5951.2020.10.03.1

Amanat Ali

引用次数: 2

Estimation of Efficiency of Use of Dairy Products Enriched with Enter Sorbent Dietary Fibers on Immunophysiological Indicators of the Rat Organism 富含膳食纤维的乳制品对大鼠机体免疫生理指标的影响

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-05-12 DOI: 10.29169/1927-5951.2020.10.03.3

N. Ablaikhanova

引用次数: 0

Parkia biglobosa (Mimosaceae): Botany, Uses, Phytochemical Properties and Pharmacological Potential 含羞草科:植物学、用途、植物化学性质和药理潜力

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-05-12 DOI: 10.29169/1927-5951.2020.10.03.4

Collen Musara

引用次数: 10

Issues of Type 2 Diabetes Disease Effective Treatment in Kazakhstan 2型糖尿病在哈萨克斯坦的有效治疗问题

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-05-12 DOI: 10.29169/1927-5951.2020.10.03.5

N. Ablaikhanova

{"title":"Issues of Type 2 Diabetes Disease Effective Treatment in Kazakhstan","authors":"N. Ablaikhanova","doi":"10.29169/1927-5951.2020.10.03.5","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.03.5","url":null,"abstract":"In his address to the people, the First President of our country, emphasized the need to introduce innovative methods of treating socially significant diseases. Among these diseases, diabetes holds a special position. More than 14,000 new cases of diabetes mellitus are officially detected annually in Kazakhstan. The real picture of the disease is difficult to compare with these data. This review discusses the prevalence of type 2 diabetes among the population of the Republic of Kazakhstan, and the causing factors such as age, race, genetic predisposition (OR = 3), obesity, glucose level and total cholesterol etc. It was found that the main complications and concomitant diseases of diabetes in residents of different regions are polyneuropathy 22.4%, diabetic retinopathy 14%, diabetic foot syndrome 13.6%, arterial hypertension 13.6% and coronary heart disease (CHD) 14.4%. Only 1.8% of the population is diagnosed with type 2 diabetes, latent manifestations of type 2 diabetes mellitus, one in four people in Kazakhstan can be sick, 38% of adults aged 20-79 suffer from prediabetes, and 8.2% with diabetes. It is believed that by 2030 in Kazakhstan, there may be about a million patients with diabetes. Diabetes mellitus, in accordance with the Code of the Republic of Kazakhstan “On the health of the people and the health care system” belongs to the category of socially significant diseases. Therefore, the study of type 2 diabetes is one of the urgent problems of the public health in Kazakhstan.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"266 1","pages":"116-122"},"PeriodicalIF":0.0,"publicationDate":"2020-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86344980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Prevalence of Iron Deficiency Anemia among Adolescent Girls in the City of Saravan - 萨拉万市少女缺铁性贫血的患病率

Journal of Pharmacy and Nutrition Sciences Pub Date : 2020-04-05 DOI: 10.29169/1927-5951.2020.10.02.4

Sabet Ghadam, M. Fararouei, M. Shahraki, Z. Sohrabi

{"title":"Prevalence of Iron Deficiency Anemia among Adolescent Girls in the City of Saravan -","authors":"Sabet Ghadam, M. Fararouei, M. Shahraki, Z. Sohrabi","doi":"10.29169/1927-5951.2020.10.02.4","DOIUrl":"https://doi.org/10.29169/1927-5951.2020.10.02.4","url":null,"abstract":"Background and Objective: Iron deficiency anemia (IDA) is the most common type of micronutrient deficiency in the world. Numerous reports indicated that adolescence is a period which has an increased risk of development of IDA. Given the importance of IDA and lack of studies in Saravan, a city of Iran, this study was performed to assess the prevalence of IDA among adolescent girls.Methods: In this cross-sectional study, 460 high-school girls were randomly selected. Demographic data was collected using a questionnaire. Knowledge, attitude and practice of participants with regard to iron deficiency anemia was measured at the beginning of the interview. Accordingly, five cc of blood sample was drawn from each student to determine the prevalence of anemia, which was defined by a hemoglobin level lower than 12 mg / dL. The level of ferritin was analyzed to confirm the IDA for students diagnosed with anemia. Ferritin level lower than 12 ?g / dl was considered as IDA. Data was analyzed using SPSS software version 22.Results: Prevalence of anemia and IDA was 24% (n = 111) and 12.6% (n = 58), respectively. Results showed that 37 % of students had good knowledge, 45. 5 % good attitude, and 6.7 % had good practice. Also, there was no significant association between IDA and socio-economic status including parental education, job, and household income (P>0.05).Conclusion: The findings of this study showed that the prevalence of IDA was moderate in Saravan city. Given the importance of IDA and its complications, further studies are needed, especially in high risk populations for IDA such as children.","PeriodicalId":16959,"journal":{"name":"Journal of Pharmacy and Nutrition Sciences","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83130399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1