Journal of Orthopaedic Science最新文献

{"title":"Biomechanical study of internal fixation methods for undisplaced femoral neck fractures with osteoporosis based on the Pauwels angle: Fixed angle device versus three cannulated screws.","authors":"Sakura Kuniyoshi, Satoshi Nakasone, Mika Takaesu, Takahiro Igei, Fumiyuki Washizaki, Kotaro Nishida","doi":"10.1016/j.jos.2025.04.001","DOIUrl":"https://doi.org/10.1016/j.jos.2025.04.001","url":null,"abstract":"<p><strong>Background: </strong>This study compared the biomechanical properties of three cannulated screws (3-CSs) and a fixed angle device (FAD) for treating undisplaced femoral neck fracture (FNF) Pauwels types I and III, using finite element analysis (FEA) models created with nonlinear material properties; accurately reflecting the bone quality of osteoporotic patients.</p><p><strong>Materials and methods: </strong>FEA involved three patients with a history of undisplaced FNF. Mesh generation was performed using the preoperative CT data. Two internal fixation models:3-CSs and FAD were created for Pauwels type I and III models with a fracture angle of 30° and 70°, respectively. Compression force and relative displacement of the fracture site, and von Mises stress (VMS) of the implants were evaluated. Data analysis involved paired t-test at p < 0.05 statistical level of significance.</p><p><strong>Results: </strong>No significant difference was seen in the compression force between the two implants for Pauwels 30° and 70°models. There was no significant difference in the relative displacement and VMS between the two implants for Pauwels 30° model. However, both relative displacement and VMS were significantly higher in 3-CSs than in FAD for Pauwels 70° model.</p><p><strong>Conclusion: </strong>Results indicate the need for FAD when treating Pawels Type III FNF with osteoporosis, since FAD fixation exhibited superior mechanical stability compared to 3-CSs. However, for the Pauwels Type I FNF, both fixation methods provided comparable stability. When considering the implant's simple and minimally invasive features, the clinical use of 3-CSs may be applicable. These findings highlight the importance of evaluating the Pauwels angle when determining the optimal fixation method for undisplaced FNF.</p>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of varus deformity on rotational geometry of the distal femur in osteoarthritic knees.","authors":"Jong-Hyub Song, Sung-Sahn Lee, Dae-Hee Lee","doi":"10.1016/j.jos.2025.04.005","DOIUrl":"https://doi.org/10.1016/j.jos.2025.04.005","url":null,"abstract":"<p><strong>Background: </strong>Accurate rotational positioning of the femoral component is one of the most important factors for successful total knee arthroplasty (TKA). The effect of varus deformity severity on distal femoral condylar geometry in the axial plane remains unclear. The purpose was to investigate the relationship between varus deformity severity and change in distal femoral posterior condyle phenotype.</p><p><strong>Methods: </strong>A total 400 patients who underwent TKA for medial osteoarthritis were enrolled between August 2015 and May 2021. Preoperative computed tomography (CT) scan was used. The angle formed by surgical and clinical transepicondylar axes (TEA) and posterior condylar line (PCL) were measured: posterior condylar angle (PCA) and condylar twist angle. The anteromedial condyle, anterolateral condyle, posteromedial condyle (PMC) posterolateral condyle lengths were also measured on CT. The distal femur geometry parameters were compared between severe (hip-knee-ankle [HKA] angle ≥10°) and mild (HKA varus <10°) varus groups.</p><p><strong>Results: </strong>The PCA angle was 0.79° smaller in the severe varus group (n = 228) than in the mild varus group (n = 172). The PMC distance was 0.86 mm lower in the severe varus group. Multiple linear regression identified the HKA angle, medial proximal tibia angle (MPTA), and PMC dimensions as predictors of the PCA. ROC analysis showed that the optimum cutoff value for a PCA <3° was an HKA angle of 8.9° (P = 0.010) and an MPTA of 85.5° (P < 0.001).</p><p><strong>Conclusion: </strong>The PCA and PMC were smaller in severe varus than in mild varus osteoarthritic knees.</p><p><strong>Study design: </strong>Case series; Level of Evidence IV.</p>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy and safety of long-term treatment, discontinuation, and extended dosing intervals of denosumab treatment for solid cancer bone metastasis: A retrospective study.","authors":"Atsushi Mihara, Ryuta Iwanaga, Keiichi Muramatsu, Koichiro Ihara, Takashi Sakai","doi":"10.1016/j.jos.2025.04.012","DOIUrl":"https://doi.org/10.1016/j.jos.2025.04.012","url":null,"abstract":"<p><strong>Background: </strong>Metastatic bone tumors in solid cancer often induce excessive local bone resorption leading to skeletal related events (SRE) which may impact patients' quality of life and survival of the primary cancer. Denosumab, a bone resorption inhibitor, is commonly used to prevent SRE in patients with solid cancer bone metastasis. However, as cancer treatment advances, patients with long-term treatment, discontinuation, and extended dosing intervals of denosumab are seen in real-world clinical practice, and questions arise regarding the efficacy and safety of such cases.</p><p><strong>Methods: </strong>We retrospective evaluated a total of 298 patients with bone metastasis of solid cancer who received denosumab treatment between 2012 and 2022. We evaluated the rates of SRE and adverse events from the medical records. To evaluate the impact of extended dosing intervals, patients were divided to short and long interval groups consisting of patients with mean dosing interval of shorter and longer than six weeks, respectively.</p><p><strong>Results: </strong>Patients with lung and other cancers, patients with prior SRE, and patients with lung metastasis showed higher risks of SRE. Osteonecrosis of the jaw (ONJ) was seen in 11.1 % of the cases and the highest incidence rate of ONJ was seen in the third year of treatment. Atypical femoral fracture was seen in one case with a dosing period of 217 weeks. Discontinuation of denosumab led to an increase of SRE, 25 weeks after the final administration. Extended dosing intervals of denosumab did not increase the SRE risk, however, did not reduce the risk of adverse events either.</p><p><strong>Conclusion: </strong>Severe adverse events should be noted in long-term treatment cases. Denosumab holiday is suggested to be limited to less than six months to mitigate SRE risk. Extending dosing intervals beyond the standard regimen did not increase the risk of SRE nor decrease the risk of adverse events.</p>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between the medial cuneiform bone morphology and the severity of hallux valgus","authors":"Futoshi Morio,&nbsp;Shota Morimoto,&nbsp;Tomoya Iseki,&nbsp;Toshiya Tachibana","doi":"10.1016/j.jos.2024.06.009","DOIUrl":"10.1016/j.jos.2024.06.009","url":null,"abstract":"<div><h3>Background</h3><div><span>It has been reported on the relationship between the medial cuneiform bone morphology, especially in terms of obliquity, and the severity of </span>hallux valgus<span> (HV), however, no consensus has been obtained. On the other hand, there are no reports on the relationship between the difference in height between the medial and intermediate cuneiforms and the severity of hallux valgus. The purpose of this study was to clarify the relationship between the medial cuneiform bone morphology and the severity of HV.</span></div></div><div><h3>Methods</h3><div>The authors retrospectively analyzed 200 feet of 116 patients who had a weightbearing anteroposterior foot radiograph taken between April 2017 and July 2022 and diagnosed with HV. Measurements included the hallux valgus angle (HVA), the intermetatarsal angle (IMA), the distal medial cuneiform angle (DMCA) and the cuneiform first-second length (C1-2D). HV groups were classified into one of three groups: mild (15 ≦ HVA&lt;30°, 9 &lt; IMA&lt;13°), moderate (30 ≦ HVA&lt;40°, 13 ≦ IMA≦20°) and severe groups (HVA≧40°, IMA&gt;20°), and the relationship to DMCA or the difference in height between the medial and intermediate cuneiforms was analyzed.</div></div><div><h3>Results</h3><div>A total of 163 feet of 93 patients were included in this study. There were significant correlations between the HVA and the DMCA (<em>r</em> = 0.47, <em>p</em> &lt; <em>0</em>.001) or the C1-2D (<em>r</em> = 0.64, <em>p</em> &lt; <em>0</em>.001). There was no significant difference in DMCA between the mild and moderate groups (<em>p</em> = <em>0</em>.14). On the other hand, significant differences in C1-2D were observed between the three groups (mild-moderate; <em>p</em> &lt; <em>0</em>.001, moderate-severe; <em>p</em> = <em>0</em>.03, mild-severe; <em>p</em> &lt; <em>0</em>.001). IMA was also positively correlated with the DMCA (<em>r</em> = 0.30, <em>p</em> &lt; <em>0</em>.001) or the C1-2D (<em>r</em> = 0.47, <em>p</em> &lt; <em>0</em>.001). However, the DMCA (<em>p</em> = <em>0</em>.07) and the C1-2D (<em>p</em> = <em>0</em>.39) did not differ significantly from IMA between the moderate and severe groups.</div></div><div><h3>Conclusions</h3><div>The difference in height between the medial and intermediate cuneiforms, referred to as C1-2D, is closely associated with the HVA. The C1-2D may influence the progression of HV and be a novel radiographic parameter that indicates severity of HV.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"30 3","pages":"Pages 456-461"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141468961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Capsular and fascial closure with barbed sutures reduces blood loss compared to traditional interrupted sutures in total hip arthroplasty","authors":"Masaya Ueno ,&nbsp;Shunsuke Kawano ,&nbsp;Masanori Fujii ,&nbsp;Satoshi Takashima ,&nbsp;Sakumo Kii ,&nbsp;Masaaki Mawatari","doi":"10.1016/j.jos.2024.07.007","DOIUrl":"10.1016/j.jos.2024.07.007","url":null,"abstract":"<div><h3>Background</h3><div>STRATAFIX, a recently introduced barbed suture device, incorporates self-anchoring, knotless sutures with higher tensile strength and enhanced tissue-holding capacity compared to traditional braided absorbable sutures. This study aimed to compare the efficacy of barbed sutures and interrupted sutures in capsular and fascial closure during total hip arthroplasty.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed the records of patients who underwent total hip arthroplasty between April 2017 and March 2021. Overall, 547 patients were evaluated, comprising 77 men and 470 women (mean age: 64.5 years). Among them, 330 patients were in the interrupted suture (control) group, while 217 were in the barbed suture (BS) group. Data on surgical time, perioperative hemoglobin, length of hospital stay, complications such as transfusions and delayed wound healing, and dislocation rates were collected during the latest outpatient follow-up and compared between the two groups.</div></div><div><h3>Results</h3><div>No differences were observed in intraoperative blood loss between the groups. However, the BS group exhibited significantly longer operative time, as well as significantly lower postoperative blood loss, total blood loss, and postoperative hemoglobin drop compared to the control group. Dislocation was reported in two cases within the control group, whereas no instances were recorded in the BS group.</div></div><div><h3>Conclusion</h3><div>The use of barbed sutures demonstrated effectiveness in reducing perioperative blood loss for capsular and fascial closure during total hip arthroplasty.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"30 3","pages":"Pages 472-477"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra- and interrater measurement reliability of lateral ankle ligament attachment locations using three-dimensional magnetic resonance imaging","authors":"Yuriko Yoshimoto ,&nbsp;Satoshi Yamaguchi ,&nbsp;Seiji Kimura ,&nbsp;Kaoru Kitsukawa ,&nbsp;Koji Matsumoto ,&nbsp;Yuki Shiko ,&nbsp;Manato Horii ,&nbsp;Shotaro Watanabe ,&nbsp;Takahisa Sasho ,&nbsp;Seiji Ohtori","doi":"10.1016/j.jos.2024.08.002","DOIUrl":"10.1016/j.jos.2024.08.002","url":null,"abstract":"<div><h3>Background</h3><div>We aimed to evaluate the intra- and interrater measurement reliability of the lateral ankle ligament attachment locations using three-dimensional magnetic resonance imaging.</div></div><div><h3>Methods</h3><div>We analysed 54 participants with a mean age of 43 years who underwent three-dimensional ankle magnetic resonance imaging and had normal lateral ligaments. Bony landmarks of the distal fibula, talus, and calcaneus were identified in the reconstructed images. The centers of the anterior talofibular ligament and calcaneofibular ligament attachments were also identified. The distances between the landmarks and attachments were measured. Two raters performed the measurements twice, and intra- and interrater intraclass correlation coefficients were calculated.</div></div><div><h3>Results</h3><div>The intrarater intraclass correlation coefficient values were between 0.71 and 0.96 for the anterior talofibular ligament attachment measurements and between 0.77 and 0.95 for the calcaneofibular ligament attachments. The interrater intraclass correlation coefficient was higher than 0.7, except for the distance between the anterior talofibular ligament superior bundle and fibular obscure tubercle. The fibular attachment of a single-bundle anterior talofibular ligament was located 13.3 mm from the inferior tip and 43% along the anterior edge of the distal fibula. The superior and inferior bundles of the double-bundle ligament were located at 43% and 23%, respectively. The calcaneofibular ligament fibular attachment was 5.5 mm from the inferior tip, at 16% along the anterior edge of the distal fibula.</div></div><div><h3>Conclusion</h3><div>The measurements of anterior talofibular ligament and calcaneofibular ligament attachment locations identified on three-dimensional magnetic resonance imaging were sufficiently reliable. This measurement method provides in vivo anatomical data on the lateral ankle ligament anatomy.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"30 3","pages":"Pages 492-498"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of early cervical functional exercise in patients after anterior cervical discectomy and fusion: A randomized controlled trial","authors":"Zhao-Rui Wang ,&nbsp;Meng Zhang ,&nbsp;Bang Wang ,&nbsp;Xing-Bin Li ,&nbsp;Ai-Bing Huang","doi":"10.1016/j.jos.2024.08.004","DOIUrl":"10.1016/j.jos.2024.08.004","url":null,"abstract":"<div><h3>Objective</h3><div>To observe the effect of early cervical functional exercise (CFE) on clinical outcomes and safety of patients after anterior cervical discectomy and fusion (ACDF).</div></div><div><h3>Methods</h3><div>Sixty patients who underwent ACDF from September 2019 to September 2020 were analyzed and randomly divided into two groups: the CFE group (27 cases) and the usual care (UC) group (33 cases). Then, all patients in the two groups received routine postoperative guidance care at the same time. Besides, the patients of the CFE group underwent a cervical functional exercise program after on the third day after ACDF. The evaluation was conducted preoperatively and at 1 week, 1 month and 6 months after surgery. The Visual Analogue Scale (VAS), Neck Disability Index (NDI) and Japanese Orthopaedic Association scores (JOA) were used to assess clinical outcomes and the safety was confirmed with routine postoperative radiological visits to ensure intervertebral stability.</div></div><div><h3>Results</h3><div>The CFE group reported lower neck pain scores on VAS at 1 month after surgery (P = 0.02) and higher postoperative scores by JOA at 1 month and 6 months, neck disability on NDI at 1 week, 1 month and 6 months after surgery (P &lt; 0.05) compared to the UC group. For postoperative dysfunction, the CFE group had more significant changes than the UC group at 1 month and 6 months after surgery (P &lt; 0.05). There was no statistical difference in cervical curves, fusion rate and fusion status between the two groups, and no revision surgery was recorded although a patient has one screw partially back out in UC group.</div></div><div><h3>Conclusion</h3><div>Our study suggested that the cervical functional exercise could decrease cervical pain and improve postoperative function in patients after ACDF. It was a safe and effective treatment for postoperative rehabilitation. The use of a postoperative collar, especially for one or two-level ACDF may not be needed.</div></div><div><h3>Protocol identifying number</h3><div>This trial was registered in the Chinese Clinical Trial Registry (registration number: ChiCTR1900025569) on 01/09/2019.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"30 3","pages":"Pages 415-422"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteoporosis should be evaluated by bone mineral density at the combination of the lumbar spine and ipsilateral femoral neck in female patients with knee osteoarthritis scheduled for knee arthroplasty: A retrospective observational study","authors":"Mitsuhiko Kubo ,&nbsp;Yuki Nosaka ,&nbsp;Takahide Hasegawa ,&nbsp;Kosuke Kumagai ,&nbsp;Yasutaka Amano ,&nbsp;Eiji Isoya ,&nbsp;Shinji Imai","doi":"10.1016/j.jos.2024.07.005","DOIUrl":"10.1016/j.jos.2024.07.005","url":null,"abstract":"<div><h3>Background</h3><div>Knee arthroplasty is a well-established surgery with good clinical outcomes. However, periprosthetic fractures and aseptic loosening negatively impact clinical outcomes, and osteoporosis is one of the causes of such complication. Osteoporosis is usually evaluated by bone mineral density of the lumbar spine and hip using dual-energy X-ray absorptiometry (DXA). However, the prevalence of this disease in patients with knee osteoarthritis scheduled for knee arthroplasty may be underestimated due to differences in the measurement sites. This study aimed to determine the appropriate measurement site for DXA that would not miss osteoporosis in female patients with knee osteoarthritis undergoing knee arthroplasty.</div></div><div><h3>Methods</h3><div>We measured bone mineral density preoperatively in the consecutive 50 female patients with knee osteoarthritis scheduled for knee arthroplasty by dual-energy X-ray absorptiometry at five sites: the lumbar spine, bilateral-total hip, and femoral neck. We then compared the prevalence of osteoporosis among the four combinations of the lumbar spine and single hip site (ipsilateral or contralateral total hip or femoral neck).</div></div><div><h3>Results</h3><div>Osteoporosis prevalence in the combination of the lumbar spine and ipsilateral or contralateral total hip was 32%, and that in the combination of the lumbar spine and contralateral femoral neck was 44%. Notably, the disease's prevalence in the combination of the lumbar spine and ipsilateral femoral neck was 50%, which was significantly higher than that in the other combinations.</div></div><div><h3>Conclusion</h3><div>Osteoporosis should be evaluated by bone mineral density in the combination of the lumbar spine and ipsilateral femoral neck in female patients with knee osteoarthritis scheduled for knee arthroplasty.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"30 3","pages":"Pages 513-517"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141788432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of surgical treatment on patient reported outcome in patients with spinal metastases from prostate cancer","authors":"Ryosuke Hirota ,&nbsp;Tsutomu Oshigiri ,&nbsp;Noriyuki Iesato ,&nbsp;Makoto Emori ,&nbsp;Atsushi Teramoto ,&nbsp;Yuki Shiratani ,&nbsp;Akinobu Suzuki ,&nbsp;Hidetomi Terai ,&nbsp;Takaki Shimizu ,&nbsp;Kenichiro Kakutani ,&nbsp;Yutaro Kanda ,&nbsp;Hiroyuki Tominaga ,&nbsp;Ichiro Kawamura ,&nbsp;Masayuki Ishihara ,&nbsp;Masaaki Paku ,&nbsp;Yohei Takahashi ,&nbsp;Toru Funayama ,&nbsp;Kousei Miura ,&nbsp;Eiki Shirasawa ,&nbsp;Hirokazu Inoue ,&nbsp;Takeo Furuya","doi":"10.1016/j.jos.2024.07.012","DOIUrl":"10.1016/j.jos.2024.07.012","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to elucidate postoperative outcomes in patients with spinal metastases of prostate cancer, with a focus on patient-oriented assessments.</div></div><div><h3>Methods</h3><div>This was a prospective multicenter registry study involving 35 centers. A total of 413 patients enrolled in the Japanese Association for Spine Surgery and Oncology Multicenter Prospective Study of Surgery for Metastatic Spinal Tumors were evaluated for inclusion. The eligible patients were followed for at least 1 year after surgery. The Frankel Classification, Eastern Cooperative Oncology Group Performance Status, visual analog scale for pain, face scale, Barthel Index, vitality index, indications for oral pain medication, and the EQ-5D-5L questionnaire were used for evaluating functional status, activities of daily living, and patient motivation.</div></div><div><h3>Results</h3><div>Of the 413 eligible patients, 41 with primary prostate cancer were included in the study. The patient-oriented assessments indicated that the patients experienced postoperative improvements in quality of life and motivation in most items, with the improvements extending for up to 6 months. More than half of the patients with Frankel classifications B or C showed improved neurological function at 1 month after surgery, and most patients presented maintained or improved their classification at 6 months.</div></div><div><h3>Conclusion</h3><div>Surgical intervention for spinal metastases of prostate cancer significantly improved neurological function, quality of life, and motivation of the patients. Consequently, our results support the validity of surgical intervention for improving the neurological function and overall well-being of patients with spinal metastases of prostate cancer.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"30 3","pages":"Pages 423-432"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher association of articular surface destruction with rheumatoid forefoot deformity arising from dislocation of the metatarsophalangeal joints in the lateral column","authors":"Yuki Suzuki ,&nbsp;Tomohiro Onodera ,&nbsp;Koji Iwasaki ,&nbsp;Masatake Matsuoka ,&nbsp;Masanari Hamasaki ,&nbsp;Eiji Kondo ,&nbsp;Norimasa Iwasaki","doi":"10.1016/j.jos.2024.07.010","DOIUrl":"10.1016/j.jos.2024.07.010","url":null,"abstract":"<div><h3>Background</h3><div>To evaluate the relationship between the pattern and severity of metatarsophalangeal (MTP) joint dislocation in the lesser toes and severity of joint destruction in rheumatoid forefoot deformities.</div></div><div><h3>Methods</h3><div>Participants comprised of 13 patients (16 feet) who underwent resection arthroplasty of the metatarsal head of the lesser toes for rheumatoid arthritis of the MTP joints. Correlations between preoperative radiographic findings and histological grades second to fifth metatarsal heads taken intraoperatively were analyzed.</div></div><div><h3>Results</h3><div>In 62 metatarsal heads, complete dislocation of the MTP joint in the lesser toes significantly resulted in severe joint destruction compared to mild or moderate dislocation (P &lt; 0.05). The proportion of severe cartilage damage in MTP joints with complete dislocation was 100 % in the 5th MTP joint, 83.3 % in the 4th MTP joint, and 58.3 % in the 2nd and 3rd MTP joints. Moreover, complete dislocation of the MTP joints in the lateral column showed the most severe joint destruction compared to that in the medial column (P = 0.03).</div></div><div><h3>Conclusion</h3><div>Complete dislocation of the MTP joint in the lateral column is related to joint destruction in rheumatoid forefoot deformities.</div></div>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":"30 3","pages":"Pages 542-547"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141988210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}