Journal of Raman Spectroscopy最新文献

{"title":"Phonon and Relaxation Dynamics in the Relaxor Ferroelectrics PbMg1/3Nb2/3O3 Using Raman Light Scattering.","authors":"S. G. Lushnikov,&nbsp;N. K. Derets,&nbsp;A. I. Fedoseev,&nbsp;R. S. Katiyar,&nbsp;J.-H. Ko","doi":"10.1002/jrs.70101","DOIUrl":"10.1002/jrs.70101","url":null,"abstract":"<div>\u0000 \u0000 <p>This paper presents the results of a study on the vibrational spectrum of the PbMg_1/3Nb_2/3O₃ (PMN) crystal using Raman light scattering across the temperature range of 100 to 1150 K. At <i>T</i> &gt; 1050 K, polarized weak modes are observed in the Raman spectra of PMN. These weak modes can be associated with local distortions of the perovskite structure. When cooling PMN, in the vicinity of <i>T</i>₁ ≈ 1050 K, the intensity of the observed modes in the Raman spectrum increases abruptly by more than an order of magnitude. The appearance of polar nanoregions (PNRs) around <i>T</i>_d ≈ 640 K is manifested only in the behavior of the intensities of Raman modes. The change of regimes in the evolution of PNRs from dynamic to static (<i>T*</i> ≈ 400 K) is accompanied by anomalies in the temperature dependences of the frequencies of low-lying optical phonons. The temperature behavior of the high-frequency mode is governed by anharmonicity, with deviations observed around <i>T*</i> ≈ 400 K. The temperature dependence of the deviations correlates well with a critical behavior of the strictly elastic neutron scattering. Frequency dispersion in the temperature behavior of low-lying phonons in the PMN has been discovered. The anisotropy of quasi-elastic light scattering (QELS) is shown. The temperature dependences of the integrated intensity and width of the vertical–vertical and vertical–horizontal polarization components of QELS differ, but have anomalies near the Burns temperature, <i>T*</i>, and at the “freezing” of PNRs (<i>T</i>_<i>vf</i> ≈ 250 K), thus revealing the entire sequence of PMN phase transformations. The obtained results are discussed in the context of modern concepts of the physics of relaxor ferroelectrics.</p>\u0000 </div>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":"643-658"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eco-Friendly Microwave Synthesis of Blue-Graphene Quantum Dots From Bougainvillea glabra and Raman Spectral Analysis","authors":"Muhammad Panachikkool,&nbsp;G. Tejaswini,&nbsp;E. Anjana Sudheer,&nbsp;D. Murali,&nbsp;Ramalinga Viswanathan Mangalaraja,&nbsp;T. Pandiyarajan","doi":"10.1002/jrs.70098","DOIUrl":"10.1002/jrs.70098","url":null,"abstract":"<div>\u0000 \u0000 <p>The production of graphene quantum dots (GQDs) with a narrow size distribution is a popular topic in current research. In this work, we developed a single-step synthesis of GQDs from the bio precursor of <i>Bougainvillea glabra</i> flower extract using a power-controlled microwave synthesiser. The Raman studies show that the GQDs are functionalised with oxygen and hydrogen, and a detailed study of the 2<i>D</i> band reveals a bilayer structure. To understand the origin of unknown peaks, the Raman spectrum for the bilayer GQDs is simulated by performing density functional theory (DFT) calculations. All the observed off-resonant peaks in the 200- to 3000-cm⁻¹ range from the theory are compared with the experimental peaks and show good agreement. The evolved peaks in the synthesised GQDs are explained in detail by DFT analysis of the vibrational modes. Additionally, the structural conformation is characterised by X-ray diffraction and high-resolution transmission electron microscopy; the absorption characteristics are examined by UV–visible spectroscopy; the emission characteristics are studied by steady-state and time-resolved photoluminescence spectroscopy; and FTIR identifies functional groups. All studies confirm that the synthesised GQDs have a bilayer structure with a narrow size distribution of 4–5 nm. The emission characteristics show that the synthesised GQDs exhibit excitation-dependent fluorescence emission.</p>\u0000 </div>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":"692-704"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Raman Signature of the Wings of the Globe Skimmer Dragonfly: Pantala flavescens","authors":"Rachel Desulme,&nbsp;Eva Gates,&nbsp;Myah Massiah,&nbsp;Malek Stafford,&nbsp;Lou Bellinghausen,&nbsp;Lillian Blanchard,&nbsp;Henry Adamson,&nbsp;Evajoice Otoo,&nbsp;Thomas D. Dovie,&nbsp;Abdul A. R. M. Rashid,&nbsp;Ebenezer Boakye,&nbsp;Calvin A. Asiedu,&nbsp;Princess W. Coffie,&nbsp;Hilda Armonle,&nbsp;Abigail Mensah,&nbsp;Kofi W. Adu,&nbsp;Jessica L. Ware,&nbsp;Lara D. LaDage,&nbsp;Rofela Combey,&nbsp;Ekaterina S. Kiseeva","doi":"10.1002/jrs.70089","DOIUrl":"10.1002/jrs.70089","url":null,"abstract":"<p>Dragonfly wings are membranous and known for their exceptional robustness, primarily due to the unique nanostructure architecture and the chemical composition of the lipids on the wing's surface. Surface properties such as antimicrobial, antiviral, and anti-wetting characteristics are the result of the chemical and physical makeup of the wing's surface. In this study, we present, for the first time, a report on the chemical components of the wing veins and the interveinal cells in the globe skimmer dragonfly (Libellulidae: <i>Pantala flavescens</i>, Fabricus, 1798) from three ecological zones in Ghana. Each component of the wing exhibits a distinct Raman fingerprint; the veins show a characteristic carbon G- and D-bands near 1590 and 1430 cm⁻¹, respectively, while the interveinal cells reveal the presence of both aliphatic carbon chains and aromatic carbon rings, with characteristic peaks around 3000 cm⁻¹ and below 1800 cm⁻¹. The presence of lightweight disordered carbon derivative in the veins and the chemical components of the interveinal cells likely contribute to the extreme strength, robustness, and durability of the wings. Furthermore, despite vast environmental differences among the three ecozones, a comparison of the Raman spectra of <i>P. flavescens</i> wings from each ecozone reveals similar chemical fingerprints, suggesting a common baseline chemical composition for the species' wings. This uniformity may be due to their highly migratory nature with a panmictic distribution across the globe.</p>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":"578-588"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/jrs.70089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantum Confinement and Anisotropic Electron–Phonon Coupling in Monolayer Phosphorene via Resonant Raman Spectroscopy","authors":"Zakariya Arbaoui,&nbsp;Mourad Boutahir,&nbsp;Brahim Fakrach,&nbsp;Hassane Chadli,&nbsp;Abdelhai Rahmani,&nbsp;Abdelali Rahmani","doi":"10.1002/jrs.70090","DOIUrl":"10.1002/jrs.70090","url":null,"abstract":"<div>\u0000 \u0000 <p>We present a first-principles investigation of the resonant Raman spectra of black phosphorene (BP)—hereafter referred to as BP—using density functional theory (DFT) as implemented in the <span>QERaman</span> package. Our calculations reveal a direct bandgap of \u0000<span></span><math>\u0000 <mn>0</mn>\u0000 <mo>.</mo>\u0000 <mn>84</mn>\u0000 <mspace></mspace>\u0000 <mtext>eV</mtext></math> in BP, consistent with previous studies. The joint density of states (JDOS) and optical absorption spectra exhibit a broad feature spanning 3–\u0000<span></span><math>\u0000 <mn>7</mn>\u0000 <mspace></mspace>\u0000 <mtext>eV</mtext></math>, suggesting strong resonant Raman enhancement in this energy range. Polarized Raman spectroscopy in both parallel (VV) and cross (VH) configurations identifies the characteristic vibrational modes of BP, which we assign to the B\u0000<span></span><math>\u0000 <msubsup>\u0000 <mrow></mrow>\u0000 <mrow>\u0000 <mtext>g</mtext>\u0000 </mrow>\u0000 <mrow>\u0000 <mn>1</mn>\u0000 </mrow>\u0000 </msubsup></math>, A\u0000<span></span><math>\u0000 <msubsup>\u0000 <mrow></mrow>\u0000 <mrow>\u0000 <mtext>g</mtext>\u0000 </mrow>\u0000 <mrow>\u0000 <mn>1</mn>\u0000 </mrow>\u0000 </msubsup></math>, A\u0000<span></span><math>\u0000 <msubsup>\u0000 <mrow></mrow>\u0000 <mrow>\u0000 <mtext>g</mtext>\u0000 </mrow>\u0000 <mrow>\u0000 <mn>2</mn>\u0000 </mrow>\u0000 </msubsup></math>, and B\u0000<span></span><math>\u0000 <msubsup>\u0000 <mrow></mrow>\u0000 <mrow>\u0000 <mtext>g</mtext>\u0000 </mrow>\u0000 <mrow>\u0000 <mn>2</mn>\u0000 </mrow>\u0000 </msubsup></math> phonon modes of the \u0000<span></span><math>\u0000 <msub>\u0000 <mrow>\u0000 <mi>D</mi>\u0000 </mrow>\u0000 <mrow>\u0000 <mn>2</mn>\u0000 <mtext>h</mtext>\u0000 </mrow>\u0000 </msub></math> point group. These findings provide critical insights into the electron–phonon coupling and optical response of BP, reinforcing its potential for optoelectronic applications.</p>\u0000 </div>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":"735-744"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of Convenient Ionic-Wind Generator for Noninvasive Enhanced Raman Spectroscopy Measurement","authors":"Pu Feng,&nbsp;Zhichen Ji,&nbsp;Qingyou Liang,&nbsp;Xiangjun Gong,&nbsp;Guangzhao Zhang","doi":"10.1002/jrs.70083","DOIUrl":"10.1002/jrs.70083","url":null,"abstract":"<div>\u0000 \u0000 <p>Raman spectroscopy suffers from inherently weak signals and persistent fluorescence interference when analyzing natural materials. To overcome these limitations, this study introduces a convenient ionic wind generator (IWG) for enhanced and fluorescence-suppressed Raman spectroscopy. The handheld system employs a tunable ionic wind source featuring a 50 nm-radius tungsten needle electrode and a 40-mesh stainless-steel mesh electrode separated by a fixed but adjustable distance. This configuration enables noncontact, substrate-free enhancement of Raman signals for both fluorescent and nonfluorescent samples. For nonfluorescent analytes (e.g., CTAB and Na₂CO₃), IWG increases the intensity of characteristic Raman peaks by 20%–40%. For fluorescent samples such as graphitic carbon nitride (g-CN), combining photobleaching (PB) with ionic wind (IW) reduces fluorescence interference by 55% and improves the signal-to-noise ratio (SNR) of key Raman peaks by 4–10 times compared to a PB-only configuration. Demonstrating compatibility with commercial Raman systems, IWG provides a noninvasive platform for enhanced material analysis, as validated using textiles, amber, and brick samples.</p>\u0000 </div>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":"705-715"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confocal Raman Microscopy of Homoepitaxial Isotopically Enriched 13C Chemical Vapour Deposited Diamond Films","authors":"M. Yu. Popov,&nbsp;A. P. Bolshakov,&nbsp;V. G. Ralchenko,&nbsp;A. A. Khomich,&nbsp;V. I. Konov,&nbsp;S. Ya. Kilin","doi":"10.1002/jrs.70095","DOIUrl":"10.1002/jrs.70095","url":null,"abstract":"<div>\u0000 \u0000 <p>Isotopically modified single-crystal diamond films are of increasing interest to researchers in view of their potential applications in photonics and spintronics, including those based on the interaction between the nitrogen-vacancy color centre and the nuclear spin of the ¹³C isotope. Confocal Raman spectroscopy is a powerful tool for profiling ¹³C/¹²C bilayer structures, especially since the two isotopes have identical optical properties but very different Raman peak positions. We performed confocal Raman mapping of a series of epitaxial, isotopically enriched ¹³C diamond layers (with a thickness ranging from 2 to 558 μm), which were grown by microwave plasma CVD on single-crystal diamond substrates with a natural isotopic composition. We also quantified the confocality parameter of the optical scheme used. Experimentally, it has been shown that confocality increases from 2 μm (for opaque objects) to approximately 30 μm along the observation axis (the <i>Z</i>-axis, which is perpendicular to the sample surface) along the path of the exciting laser beam. Nevertheless, the position of the film/substrate interface can be defined with an accuracy of a few micrometres. Finally, we demonstrate the use of the same confocal system for depth profiling of silicon-vacancy (SiV) color center, another important photon source, in the photoluminescence spectrum of ¹³C diamond, and we found an accumulation of the SiV at the film/substrate interface.</p>\u0000 </div>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":"674-682"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temperature-Dependent Investigation of the S-Branch Raman Linewidth in CO2 via Time-Resolved Rotational CARS","authors":"Henry Misoi,&nbsp;Joy Muriithi,&nbsp;Jonas I. Hölzer,&nbsp;Nancy W. Karuri,&nbsp;Thomas Seeger","doi":"10.1002/jrs.70096","DOIUrl":"10.1002/jrs.70096","url":null,"abstract":"<p>The temperature-dependent coherence decay behavior of pure CO₂ and the self-broadened rotational Raman linewidths were investigated between 295 and 1900 K using a picosecond time-domain pure rotational coherent anti-Stokes Raman scattering (RCARS) approach. To balance rapid collisional dephasing and temporal resolution, the cell pressure was reduced from 1000 to 750 mbar below 1200 K, which was successfully accounted for during the computation of the Raman linewidth. The decay behavior provides insight into the collision dynamics of the CO₂ molecules in the gas phase, which is important for gas dynamics modeling. Furthermore, the spectral signatures of the collisional dynamics, reflected in the S-branch Raman linewidth, constitute an important aspect of accurate spectral modeling for gas-phase diagnostic applications using the RCARS technique. The RCARS spectra for different probe delays exhibit temperature-dependent changes in the spectral envelope that are distinct from other small molecules. A region of lower Raman linewidths observed around <i>J\"</i> = 76 and <i>J\"</i> = 42 and higher Raman linewidths at <i>J\"</i> = 60 and <i>J\"</i> = 90 indicate slower decays and faster decays compared with the expected monotonic trend, respectively. This hints at the existence of multiple decay and energy transfer channels specific to CO₂. These may be an indication of coherence transfer in equilibrium CO₂, which was recently found in optically centrifuged CO₂. These specific collisional dynamics result in a nonmonotonic trend of the S-branch Raman linewidth with rotational quantum number, which is not accounted for in previously available linewidth data. Therefore, the application of the presented Raman linewidths is expected to greatly enhance spectral modeling and RCARS gas-phase diagnostics.</p>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":"725-734"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/jrs.70096","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Featured Cover","authors":"Rachel Desulme,&nbsp;Eva Gates,&nbsp;Myah Massiah,&nbsp;Malek Stafford,&nbsp;Lou Bellinghausen,&nbsp;Lillian Blanchard,&nbsp;Henry Adamson,&nbsp;Evajoice Otoo,&nbsp;Thomas D. Dovie,&nbsp;Abdul A. R. M. Rashid,&nbsp;Ebenezer Boakye,&nbsp;Calvin A. Asiedu,&nbsp;Princess W. Coffie,&nbsp;Hilda Armonle,&nbsp;Abigail Mensah,&nbsp;Kofi W. Adu,&nbsp;Jessica L. Ware,&nbsp;Lara D. LaDage,&nbsp;Rofela Combey,&nbsp;Ekaterina S. Kiseeva","doi":"10.1002/jrs.70139","DOIUrl":"10.1002/jrs.70139","url":null,"abstract":"<p>The cover image is based on the article <i>Raman Signature of the Wings of the Globe Skimmer Dragonfly: Pantala flavescens</i> by Rachel Desulme et al., https://doi.org/10.1002/jrs.70089.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/jrs.70139","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Multi-Scale Residual Network Based on Kolmogorov–Arnold Networks Combined With Raman Spectroscopy for Rapid Diagnosis of Membranous Glomerulonephritis","authors":"Chenjie Chang,&nbsp;Zhenzhen Wei,&nbsp;Chen Chen,&nbsp;Shengquan Liu,&nbsp;Jin Gu,&nbsp;Cheng Chen","doi":"10.1002/jrs.70085","DOIUrl":"10.1002/jrs.70085","url":null,"abstract":"<div>\u0000 \u0000 <p>Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults and a frequent contributor to end-stage renal disease (ESRD). In recent years, the prevalence of MN has shown an upward trend, with a notably increasing incidence in younger populations. Currently, methods such as renal biopsy and renal function tests are used to diagnose MN. Conventional diagnostic methods carry risks of infection and other complications, in addition to being costly and requiring advanced technical expertise. As a result, the early detection of MN necessitates the development of a diagnostic method that is quick, inexpensive, and noninvasive. This paper proposes a multi-scale residual network (MSRKan) based on Kolmogorov–Arnold networks (KANs) for processing Raman spectroscopic data obtained from the serum of MN patients. The model captures both large-scale global information and fine-grained local details of spectral data, minimizing information loss and enhancing performance. Compared with traditional models, MSRKan achieves the highest accuracy (98.18%), with precision, recall, and F1-score of 100%, 96.67%, and 98.31%, respectively. Additionally, this study verifies for the first time the effectiveness of KAN in spectral data processing. These results demonstrate that the combination of the MSRKan algorithm and Raman spectroscopy enables rapid diagnosis of MN, which holds significant clinical value for patients and enhances the accuracy of computer-aided medical diagnosis. The source code for the MSRKan model is publicly available on GitHub at: https://github.com/cj764/msrkan.</p>\u0000 </div>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":"601-613"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147667983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urine SERS Analysis of Sanda Athletes Before and After Competition","authors":"Mei Liu,&nbsp;Jiayu Li,&nbsp;Yanzhao Chen,&nbsp;Xinyi Fan,&nbsp;Xuefeng Xi,&nbsp;Gaixia Hou,&nbsp;Renming Liu,&nbsp;Hao Hong","doi":"10.1002/jrs.70100","DOIUrl":"10.1002/jrs.70100","url":null,"abstract":"<div>\u0000 \u0000 <p>Surface-enhanced Raman spectroscopy (SERS) technology can be utilized for the trace detection of fingerprint information in biological fluids at the molecular level, which enables an early prediction of the metabolic status and health conditions of living organisms. Therefore, this technology holds significant implications for human health and disease monitoring. Herein, the capability of using SERS technology for label-free and noninvasive detection of the metabolic components in the urine of Sanda athletes before and after competitions is presented. By leveraging the colloidal gold (core)-silver shell nanoparticles as SERS substrate, we performed urine SERS measurements of 14 Sanda athletes before and after competitions. Additionally, the methods of principal components analysis (PCA) combined with independent sample <i>t</i>-test were employed to analyze the athletes' urine SERS spectra. The analysis reveals significant increases in the levels of uric acid, urea, phenylalanine, and tryptophan in the urine of Sanda athletes before and after competitions. This study highlights the potential of SERS spectroscopy for label-free, noninvasive, and rapid molecular-level urine analysis in athletes during their competitions. These findings may provide valuable guidance and serve as a useful reference for athletes regarding the monitoring of physical damage and the supplementation of nutrition during both training and competitions.</p>\u0000 </div>","PeriodicalId":16926,"journal":{"name":"Journal of Raman Spectroscopy","volume":"57 4","pages":"716-724"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}