Journal of Radiation Research and Applied Sciences最新文献

{"title":"Evaluation of proton therapy dose in breast cancer with boron agent based on GATE Monte Carlo code","authors":"Fereshteh Mollaee Bijarpasi,&nbsp;Alireza Sadremomtaz","doi":"10.1016/j.jrras.2025.101311","DOIUrl":"10.1016/j.jrras.2025.101311","url":null,"abstract":"<div><h3>Purpose</h3><div>Proton Boron Capture Therapy (PBCT) has been introduced as a proposed method of increasing the proton therapy dose. The interaction mechanism of this reaction is p + ¹¹B → 3α<strong>.</strong> This research was carried out to evaluat<strong>e</strong> the dose of proton beams with boron agents.</div></div><div><h3>Methods</h3><div>All the simulations were done with Monte Carlo GATE code. First, the proton beam and the breast phantom were simulated, and then different boron concentrations were created in the tumor area. Finally, using the dose actor, the amount of the deposited dose, the deposited energy, and the dose of secondary alpha particles in the tumor area were calculated.</div></div><div><h3>Results</h3><div>The simulation results show that at a concentration of 65 ppm of 11B, the dose changes are less than 1% compared to the tumor area without boron, and the depth of the Bragg peak remains unchanged. By increasing the concentration of boron in the tumor area, the deposited dose and the depth of the Bragg peak decrease. In pure ¹¹B, the deposited dose is reduced to half of the original amount.</div></div><div><h3>Conclusion</h3><div>By placing different concentrations of boron agents, the physical aspects and simulation results did not show that boron is effective in increasing the dose in proton therapy. Therefore, ¹¹B cannot be used as a dose-enhancing agent in proton therapy.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101311"},"PeriodicalIF":1.7,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing flow and heat transfer in industrial processes: The potential of trihybrid nanofluid and thermal-radiation using Hamilton-Crosser and Xue models","authors":"Ahmed M. Galal ,&nbsp;Abdelkader Mabrouk ,&nbsp;Hawzhen Fateh M. Ameen ,&nbsp;Munawar Abbas ,&nbsp;Dennis Ling Chuan Ching ,&nbsp;Mohammad Saqlain Sajjad ,&nbsp;Abdullah A. Faqihi ,&nbsp;Lioua Kolsi ,&nbsp;Abid Ali Memon ,&nbsp;Ilyas Khan","doi":"10.1016/j.jrras.2025.101322","DOIUrl":"10.1016/j.jrras.2025.101322","url":null,"abstract":"<div><div>The present study uses the Hamilton-Crosser thermal conductivity and Xue models to study the impacts of thermal radiation on thermal boundary layer convective flow of propylene glycol-based trihybrid nanofluid across a spinning disk with thermal slip and velocity slip conditions. This recommended model evaluates the performance of two popular trihybrid nanofluid models, the Xue model and Hamilton-Crosser model. In chemical reactors, thermal power plants, and advanced cooling systems, this model allows for the accurate prediction and improvement of thermal conductivity and energy efficiency. Especially in high-temperature settings, companies can improve heat dissipation, lower energy consumption, and increase process stability by utilizing the outstanding thermal capabilities of trihybrid nanofluids. When effective heat management is essential, such as in microelectronics cooling, automotive thermal management, and renewable energy systems, this method is especially helpful. By comparing the Xue and Hamilton-Crosser models, it is possible to optimize the flow parameters and nanoparticle composition, which improves thermal systems' stability and energy efficiency. The transformation of significant similarity is used to build ordinary differential equations for the nonlinear dimensionless system. This problem can be resolved mathematically using the Bvp4c approach. The outcomes demonstrate that although the thermal profile improves as the Brinkman's number increases, the rate of heat transmission decreases.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101322"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Assessment of undergraduates nursing students’ knowledge toward MRI safety: Cross-sectional study” [Journal of Radiation Research and Applied Sciences Volume 17, Issue 1, March 2024, 100801]","authors":"Ali Alyami ,&nbsp;Naif Majrashi ,&nbsp;Lama Hazazi ,&nbsp;Abeer Abdu Ruqayi ,&nbsp;Basmah Yahya Amri ,&nbsp;Waheed Abdulmajed ,&nbsp;Hamoud M. Masmali ,&nbsp;Turkey Refaee ,&nbsp;Wael Ageeli ,&nbsp;Bandar Alwadani ,&nbsp;Yahia Madkhali ,&nbsp;Abdullah A. Althobity ,&nbsp;Abdullah Ali Madkhali ,&nbsp;Ali Al-Radaideh","doi":"10.1016/j.jrras.2025.101323","DOIUrl":"10.1016/j.jrras.2025.101323","url":null,"abstract":"","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101323"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling to radiotherapy, environmental and engineering data: Using a new approach to generating family of distributions","authors":"Ahmed W. Shawki ,&nbsp;Mohamed Kayid ,&nbsp;Oluwafemi Samson Balogun ,&nbsp;Tamer S. Helal","doi":"10.1016/j.jrras.2025.101317","DOIUrl":"10.1016/j.jrras.2025.101317","url":null,"abstract":"<div><div>In this paper, we discuss a new approach to statistical distributions that has been suggested and is termed the alpha power transformation Burr X family of distributions. The newly offered class of distributions is the mixing between the alpha power transformation and the Burr X class of distributions. This new class helps evaluate data from the real world because it is analytically possible and can be utilized. Many asymmetrical submodels were included in the newly proposed class of distributions. We offer four new submodels that belong to a new class of distributions. These submodels are referred to as the alpha power transformation Burr X exponential distribution, the alpha power transformation Burr X Rayleigh distribution, alpha power transformation Burr X Lindley distribution, and the alpha power transformation Burr X Weibull distribution. The expansion of the alpha power transformation Burr X-G density function was computed to obtain additional statistical characteristics of the newly suggested family of distributions. Several statistical attributes of the alpha power transformation Burr X-G class were obtained. These characteristics include a quantile function, ordinary moments, conditional moments, and moment-generating functions. Estimation of parameters is performed using the maximum likelihood estimation approach. An investigation of the simulation was conducted to evaluate the performance of the maximum likelihood estimation approach. Four data sets taken from the actual world related to radiotherapy, environmental, and engineering sciences were used to demonstrate the significance and application of the suggested family</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101317"},"PeriodicalIF":1.7,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduction of effective dose in vascular interventions to enhance radiation safety","authors":"Imen Hammami ,&nbsp;Ghada A. Khouqeer ,&nbsp;Mohammed Sallah ,&nbsp;Faouzi Hosni ,&nbsp;Salam Labidi","doi":"10.1016/j.jrras.2025.101312","DOIUrl":"10.1016/j.jrras.2025.101312","url":null,"abstract":"<div><h3>Background</h3><div>Recent advancements in imaging devices have improved X-ray efficiency but also raised concerns about radiation exposure risks. To ensure safety, it is important to adopt dose reduction protocols, regular equipment maintenance, and the ALARA principle, alongside continuous staff education to minimize radiation-related health risks while optimizing procedure benefits.</div></div><div><h3>Objective</h3><div>This study aims to assess the impact of a series of proposed dose reduction processes on reducing the absorbed X-ray dose for patients undergoing interventional procedures.</div></div><div><h3>Materials and method</h3><div>A cohort of 64 medium-sized adult patients underwent numerous X-ray interventions including Transluminal Angioplasty, Biliary Drainage, Chemoembolization, Phlebography, and Fistulography. These interventional procedures were accomplished by using the fluoroscopic X-ray device (AXIOM Artis-Zee, Siemens) in the vascular room of Charles Nicolle Hospital in Tunisia. The dose reduction process applied different CARE techniques along with recommendations from the literature. Doses obtained after the reduction processes were assessed against those from daily practice. Statistical analyses were conducted using the H-<em>test</em>, implemented via R software, to assess the data. Physicians evaluated the image quality during the execution of the X-ray interventions.</div></div><div><h3>Results</h3><div>The reduction in terms of effective dose for diagnostic vascular interventions was 18% for fistulography and 25% for phlebography. For the therapeutic procedures, dose reductions were 19% for Transluminal Angioplasty, 27% for Chemoembolization, and 28% for Biliary Drainage. The statistical analysis of the three recorded indicators (Dose Area Product, exposure time, and effective dose) revealed significant differences (<em>p-</em>value &lt;0.05) before and after the dose reduction process. The image quality was maintained acceptable to perform interventional procedures (p &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>The obtained results highlight how the dose reduction processes yielded considerable reductions across all studied X-ray vascular interventions while producing high-quality images that fulfilled diagnostic and therapeutic requirements.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101312"},"PeriodicalIF":1.7,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermally radiative MHD Jeffery-Hamel flow in a convergent-divergent conduit: A hybrid nanofluid fluid model under nanoparticles shape factor impact","authors":"Daoudi Safa ,&nbsp;Sari mohamed Rafik ,&nbsp;Farhan lafta Rashid ,&nbsp;Dhahri Hacen ,&nbsp;Mhimid Abdallah ,&nbsp;Kezzar Mohamed ,&nbsp;Ilyas Khan ,&nbsp;Muhammad sabaoon Khan ,&nbsp;Badria almaz ali Yousif","doi":"10.1016/j.jrras.2025.101314","DOIUrl":"10.1016/j.jrras.2025.101314","url":null,"abstract":"<div><div>The purpose of this research is to analyze the heat transfer and the magnetohydrodynamic flow properties of synthesize J-H hybrid nanofluids with emphasis on the impacts of thermal radiation and hydro-magnetic field and heat generation from source/sink. Besides, the research also looks at the effects of the shape factor with the nanoparticle: Sphere-NP, Column-NP, and Lamina-NP, and the effects of the basic fluid blends, like ethylene glycol and water variant 30%:70%. In this situation two nanoparticles are considered (i.e. <span><math><mrow><mi>Z</mi><mi>r</mi><msub><mi>O</mi><mn>2</mn></msub></mrow></math></span> and <span><math><mrow><mi>M</mi><mi>o</mi><msub><mi>S</mi><mn>2</mn></msub></mrow></math></span>). We derive nonlinear ODEs from the governing nonlinear PDEs utilizing the similarity transformations. The model's performance is assessed through both numerical and analytical solutions, the analytical solution has been constructed using the Duan–Rach Approach (DRA) and numerical using the Fourth order Runge-Kutta Method (RK4) illustrating the influence of key factors on velocity and temperature profiles, as well as skin friction and Nusselt numbers. The present results show that thermal radiation and heat generation parameters have a beneficial impact on heat transference across the convergent and divergent channels; thus, it is vital to consider radiation and heat generation effects while modeling hybrid nanofluids thermally. External magnetic field influence also affects the flow behaviour; with changes in magnetic field strength influencing the velocity and thermal field of the nanofluids. In fact, the magnetic field has a stabilizing effect where the reversal flow is entirely excluded. In addition, it has been revealed that different base fluids exhibit different thermal and flow behaviors when mixed with hybrid nanoparticles which supports the use of the right base fluids in certain applications.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101314"},"PeriodicalIF":1.7,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance of thermal radiation in stability analysis and triple solutions for magnetized micropolar Buongiorno's nanofluid model","authors":"Khuram Rafique ,&nbsp;Shamaila Kanwal ,&nbsp;Shafiullah Niazai ,&nbsp;Ali Ahmed Alqahtani ,&nbsp;Ilyas Khan","doi":"10.1016/j.jrras.2025.101316","DOIUrl":"10.1016/j.jrras.2025.101316","url":null,"abstract":"<div><div>The aim of this research is to investigate the impact of thermal radiations on micropolar nanoliquid flow over a stretching/shrinking surface. Further, heat generation or absorption along with Soret effects incorporated in energy and mass equations. Additionally thermal, velocity and concentration slips are considered along with porous surface. By applying similarity transformations, the nonlinear PDEs are transformed into the set of ODEs. These equations are then solved numerically by employing bvp4c technique in MATLAB. Due to the presence of more than one solution, the stability analysis is performed. Therefore, it is found that first solution is stable (physically realizable in practice) while the others are unstable. It is seen that three different results are achieved depending on the critical value, which show that all solutions are connected at these critical values and the boundary layer divides behind these critical values, representing that the solution is not stable. Furthermore, the velocity of the liquid diminishes with the increment in magnetic parameter. Further temperature distribution enhances with the increment in Brownian factor while diminishes against radiations effect. Moreover, Soret effect enhances concentration profile. Further this study helps in engineering applications including spinning process, polymer industry etc.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101316"},"PeriodicalIF":1.7,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dosimetric comparison of the noncoplanar volumetric modulated arc therapy with flattening filter free beams and flattened beams for the whole brain radiotherapy with hippocampus avoidance","authors":"Xiao-long Cheng,&nbsp;Ji-ping Liu,&nbsp;Bin-bing Wang,&nbsp;Long Sun","doi":"10.1016/j.jrras.2025.101320","DOIUrl":"10.1016/j.jrras.2025.101320","url":null,"abstract":"<div><h3>Objective</h3><div>A comparative analysis is conducted to examine dosimetric discrepancies between flattening filter-free (FFF) and flattened (FF) beam noncoplanar volumetric modulated arc therapy (NCVMAT) plans for whole brain radiotherapy (WBRT) with hippocampus avoidance.</div></div><div><h3>Methods</h3><div>Fifteen patients who underwent WBRT with hippocampus avoidance were randomly selected. Individual treatment plans were created on the Infinity accelerator for FF-NCVMAT and FFF-NCVMAT, both with a prescribed dose of 30Gy/10F and identical plan parameters using the Monaco treatment planning system (TPS). The plans were designed to meet the dosimetric requirements specified in RTOG 0933. Both groups achieved a planning target volume (PTV) coverage rate of 95% for the prescribed dose. The dosimetric parameters, including machine units (MU), delivery time (DT), plan modulation factor (MF), and gamma pass rate(GPR) were compared between the two plans.</div></div><div><h3>Results</h3><div>There were no significant differences in minimum dose (Dmin) and homogeneity index (HI) of the PTV between the FFF-NCVMAT group and the FF-NCVMAT group (P = 0.828, 0.453). However, utilization of the FFF mode effectively reduced maximum dose (Dmax) of the PTV and improved conformity index (CI), with statistical significance observed (P = 0.010, 0.006). The MF and GPR between both plans were similar (P = 0.599,0.130). Within the FFF-NCVMAT group, Dmax, D100%, and mean dose (Dmean) of the hippocampus were significantly smaller compared to those in the FF-NCVMAT group, demonstrating statistically significant differences(P &lt; 0.001, P &lt; 0.001, P &lt; 0.001). In the FFF-NCVMAT group, the Dmax of the left and right optic nerves and optic chiasm were all smaller than those in the FF-NCVMAT group, and the differences were statistically significant (P = 0.027, 0.033, 0.043). The doses of other organs at risk (OARs) such as lens and eyes were all controlled within the clinically safe dose range, and there was no statistically significant difference between the two plans (P = 0.912, 0.179; P = 0.850, 0.855). The MU of the FFF-NCVMAT group was higher than that of the FF-NCVMAT group, but the DT was shorter than that of the FF-VMAT group, and the differences were statistically significant (P &lt; 0.001, P &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The FF-NCVMAT and FFF-NCVMAT plans both meet the clinical requirements of RTOG 0933, and their complexity is comparable. However, the FFF-NCVMAT plan offers an advantage in terms of hippocampus and lens protection. Despite having a higher MU, the FFF mode has a shorter DT, resulting in improved treatment efficiency. Therefore, it is recommended to consider using the FFF-NCVMAT plan for HA-WBRT.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101320"},"PeriodicalIF":1.7,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consequences of thermal radiation and entropy generation in magnetohydrodynamic Darcy-Forchheimer flow of nanomaterials","authors":"Muhammad Yasir ,&nbsp;M. Nadeem Khan ,&nbsp;Taoufik Saidani ,&nbsp;Ali Alzahrani","doi":"10.1016/j.jrras.2025.101308","DOIUrl":"10.1016/j.jrras.2025.101308","url":null,"abstract":"<div><div>Recently nanomaterials much attention has been paid to nanoparticles and their manufacturing processes. Researchers attracted towards exploring the nanoliquid transport and thermal transport analyses subject to some physical phenomenon by using different condition. Also keeping in mind, the enhanced efficiency of thermal transport related device in nanofluid. Here we discussed the entropy generation and partial slip in mixed convective flow of nanomaterial bounded by a stretching boundary are addressed. First order chemical reaction and radiation are taken. Porous medium and permeable sheet are considered. Nonlinear formulation is solved by homotopy analysis technique (HAM). Solutions are analyzed for velocity, concentration, thermal field, entropy rate, heat transport rate, Bejan number and mass transfer rate. Higher magnetic fields have opposite effect on temperature and velocity. An enhancement in temperature and entropy generation rate are seen through radiation parameter. Concentration has opposite trend for both Brownian and thermophoresis parameters. Entropy rate has increasing effect for magnetic parameter. Main results are synthesized in the conclusions.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101308"},"PeriodicalIF":1.7,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive analysis of vocal cord fixation: Clinical profiles, CT imaging, and laryngeal electromyography outcomes","authors":"Xiaorong Su ,&nbsp;Liqing Yao ,&nbsp;Peiyu Shao","doi":"10.1016/j.jrras.2025.101313","DOIUrl":"10.1016/j.jrras.2025.101313","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the diagnostic efficacy of a comprehensive multimodal approach, integrating clinical profiles, high-resolution CT imaging, and laryngeal electromyography (LEMG), for vocal fold immobilization. It sought to enhance diagnostic precision, differentiate between neurogenic and mechanical etiologies, and improve treatment outcomes while assessing the cost-effectiveness of this strategy.</div></div><div><h3>Materials and methods</h3><div>A prospective cohort of 59 patients diagnosed with vocal fold immobilization underwent comprehensive evaluation using clinical assessment, CT imaging, and LEMG over two years. High-resolution CT imaging identified structural abnormalities, while LEMG assessed neuromuscular integrity. The data were analyzed to determine diagnostic accuracy, sensitivity, and specificity of individual and combined modalities. Cost-effectiveness was evaluated using incremental cost-effectiveness ratios (ICERs), and outcomes were tracked over a 12-month follow-up period.</div></div><div><h3>Results</h3><div>The multimodal approach achieved a diagnostic accuracy of 94.6%, significantly outperforming standalone modalities (p &lt; 0.001). CT imaging identified structural anomalies in 76.3% of cases, while LEMG detected neurogenic dysfunction in 82.5% of patients. Combined modalities showed high sensitivity (93.7%) and specificity (95.2%). Tailored interventions, including surgery (42.4%), voice therapy (37.3%), and medical management (20.3%), led to a 42.3-point improvement in Voice Handicap Index scores, compared to 28.7 points for limited diagnostic approaches (p &lt; 0.001). The comprehensive strategy reduced recovery times by 40% and demonstrated cost-effectiveness with an ICER of $8400 per quality-adjusted life year.</div></div><div><h3>Conclusion</h3><div>Integrating clinical assessment, CT imaging, and LEMG provides superior diagnostic accuracy and treatment outcomes for vocal fold immobilization. This evidence-based, cost-effective strategy establishes a new standard for managing complex laryngeal conditions and underscores the importance of multidisciplinary care.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 1","pages":"Article 101313"},"PeriodicalIF":1.7,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}