Abdullah Alhushaybari , Umar Farooq , Muhammad Imran , Shan Ali Khan , Walid Aich , Wajdi Rajhi , Dennis Ling Chuan Ching , Ilyas Khan
{"title":"Thermal radiation effect on SiO2–MoS2/Water hybrid nanofluids with Darcy–Forchheimer flow with Cattaneo–Christov heat flux over a permeable surface","authors":"Abdullah Alhushaybari , Umar Farooq , Muhammad Imran , Shan Ali Khan , Walid Aich , Wajdi Rajhi , Dennis Ling Chuan Ching , Ilyas Khan","doi":"10.1016/j.jrras.2025.101914","DOIUrl":"10.1016/j.jrras.2025.101914","url":null,"abstract":"<div><div>This research offersa computational and numerical analysis of SiO<sub>2</sub>/water nanofluid and SiO<sub>2</sub>–MoS<sub>2</sub>/water hybrid nanofluid under Darcy–Forchheimer flow conditions across a permeable surface. The model incorporates the consequences of the Cattaneo–Christovthermal radiation, heat flux model, viscous dissipation, and variable solid volume fractions of nanoparticles to evaluate the behavior of the fluids. The controlling nonlinear partial differential equations are converted into a system of ordinary differential equations and numerically resolved utilizing MATLAB's BVP4C solver in conjunction with the shooting method. bResultsreveal that hybrid nanofluids, particularly the SiO<sub>2</sub>–MoS<sub>2</sub>/water composition, significantly outperform mono-nanofluids in terms of thermal conductivity, heat transfer efficiency, and friction reduction. SiO<sub>2</sub>/water nanofluid is commonly used in electronic cooling, solar collectors, automotive radiators, biomedical devices, and heat exchangers due to its good thermal performance, chemical stability, and low cost making it ideal for safe, non-toxic heat transfer applications. In contrast, the SiO<sub>2</sub>–MoS<sub>2</sub>/water hybrid nanofluid offers superior thermal and tribological properties, making it highly suitable for advanced heat exchangers, solar thermal systems, cutting and grinding operations, geothermal energy systems, and aerospace cooling technologies. The synergistic enhancement provided by MoS<sub>2</sub> greatly improves both heat transfer and lubrication, positioning this hybrid nanofluid as a promising candidate for next-generation thermal management solutions.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101914"},"PeriodicalIF":2.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144932374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LingChuan Liu, Zhengcheng Dong, Jian Ke Xia, Qi Xu, Wang Ting Chen
{"title":"Application of virtual touch tissue imaging quantification (VTIQ) for diagnosing vascular penile erectile dysfunction","authors":"LingChuan Liu, Zhengcheng Dong, Jian Ke Xia, Qi Xu, Wang Ting Chen","doi":"10.1016/j.jrras.2025.101926","DOIUrl":"10.1016/j.jrras.2025.101926","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the value of virtual touch tissue imaging quantification (VTIQ) in the diagnosis of vascular penile erectile dysfunction.</div></div><div><h3>Methods</h3><div>Sixty male examinees from January 2024 to March 2025 were selected as the study subjects. After erection was induced by oral sildenafil combined with visual and auditory stimulation, the subjects were divided into normal group, arterial ED group, venous ED group and mixed ED group using color Doppler ultrasound (CDUS) diagnosis as the gold standard, and the cavernosal shear wave velocity (SWV) of each group was measured using VTIQ technique to compare the differences between groups and analyze the feasibility of VTIQ in the diagnosis of vascular penile erectile dysfunction.</div></div><div><h3>Results</h3><div>The measurement of different positions of corpus cavernosum affected the shear wave velocity (P < 0.05). There was a significant difference in shear wave velocity between the corpus cavernosum with normal erectile function and the corpus cavernosum with erectile dysfunction. Shear wave velocity in the corpus cavernosum was correlated with the location measured, the presence of vascular penile erectile dysfunction, and the peak velocity of the corpus cavernosum artery (all P < 0.05). The diagnostic efficacy of cavernosal shear wave velocity for vascular penile erectile dysfunction (arterial ED, venous ED, and mixed ED) was 0.93 (95 % CI: 0.87–0.98), the optimal cutoff value of cavernosal shear wave velocity was 2.85 m/s, the sensitivity was 88.9 % (88.9 % of ED patients could be correctly identified), and the specificity was 86.7 % (86.7 % of normal subjects could be correctly excluded).</div></div><div><h3>Conclusion</h3><div>Virtual touch tissue imaging quantification technique(VTIQ) can quantitatively evaluate the hardness of corpus cavernosum and provide reliable imaging evidence for the diagnosis and treatment of vascular ED, which has high clinical value.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101926"},"PeriodicalIF":2.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144932335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mouloud Aoudia , Munawar Abbas , Faiza Benabdallah , Ibtehal Alazman , Nouf Abdulrahman Alqahtani , Ilyas Khan , Abdullah A. Faqihi , Saba Liaqat
{"title":"Radiation effects on gyrotactic microbes in tetra hybrid nanofluid: Enhancing mass and heat transfer processes in microfluidic and bio-convective systems","authors":"Mouloud Aoudia , Munawar Abbas , Faiza Benabdallah , Ibtehal Alazman , Nouf Abdulrahman Alqahtani , Ilyas Khan , Abdullah A. Faqihi , Saba Liaqat","doi":"10.1016/j.jrras.2025.101921","DOIUrl":"10.1016/j.jrras.2025.101921","url":null,"abstract":"<div><div>The goal of this study is to look at how Stephan blowing and radiation influences the Marangoni convective flow of a tetra hybrid nanofluid across a heated disk containing gyrotactic microorganisms. The model can be used to increase the effectiveness of biosensing and optimize heat management in microfluidic devices. It also helps pharmaceutical and biological procedures by improving nutrition transport and microbial control in lab-on-a-chip systems. The proposed method has significant applications in sophisticated heat management systems and biomedical engineering. Through the examination of thermophoretic particle deposition impacted by radiative heat transmission and Stephan blowing in tetra hybrid nanofluid containing gyrotactic microbes, this study provides information for improving the efficiency of mass and heat transmission in microscale cooling technologies, including electronic cooling and microfluidic devices. Furthermore, in applications where regulated particle mobility and deposition are critical for performance optimization, such as bioreactors, targeted drug delivery, and microbial fuel cells, understanding microbe behaviour might be beneficial. The transformation strategy was used to generate a highly nonlinear system of ordinary differential equations (ODEs). Given the system of transformed equations' highly nonlinear nature, a numerical solution was presented and assessed using the shooting method (bvp4c). The results reveal that as the Stephan blowing parameter increases, the velocity and thermal profiles rise, while the solutal profile falls.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101921"},"PeriodicalIF":2.5,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144932865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed A. Abdelkawy , Atef F. Hashem , Mahmoud El-Morshedy , Hend S. Shahen
{"title":"On fitting disability in Saudi Arabia and radiation data: Using the alpha power transformed Rayleigh inverted Weibull distribution","authors":"Mohamed A. Abdelkawy , Atef F. Hashem , Mahmoud El-Morshedy , Hend S. Shahen","doi":"10.1016/j.jrras.2025.101881","DOIUrl":"10.1016/j.jrras.2025.101881","url":null,"abstract":"<div><div>This study presents an in-depth analysis of the distribution of disability in Saudi Arabia according to age groups, as documented in the latest KSA Census of 2022. “4.2%” of the population of the Kingdom experiences difficulties or disabilities. The prevalence of disabilities increases significantly with age, where the percentage of people with disabilities is very low in the younger age groups and increases dramatically among the older individuals. These findings provide valuable information for policy makers in developing targeted intervention programs for people with disabilities based on age groups. Traditional probability distributions may, on occasion, fail to take into account this complexity, which can lead to inaccurate conclusions being drawn instead. So, in this article, we introduce a new three-parameter model called the alpha-power transformed Rayleigh inverted Weibull distribution (APTRIWD) to solve this issue. The probability density curves of APTRIWD provide evidence that it can be used in the analysis of disability data in Saudi Arabia and radiation data, demonstrating its practical applicability. Due to the fact that the hazard rate function (HRF) for APTRIWD can exhibit J-shaped, growing, and declining patterns, researchers have a great deal of flexibility when it comes to constructing statistical models for research on disability concerns. Some important statistical properties of the new suggested model are discussed. The maximum likelihood estimation method is utilized to determine the parameters of the machine learning model. For the purpose of determining the efficiency of maximum likelihood estimators, a Monte Carlo simulation analysis is performed. The proposed distribution was evaluated using three datasets related to disability concerns in Saudi Arabia and radiation data. The APTRIWD exhibited superior goodness of fit compared to several models. The APTRIWD is recommended for data modeling in fields such as disability challenges due to its exceptional fit capabilities and radiation data.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101881"},"PeriodicalIF":2.5,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144932376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Munawar Abbas , Shaaban M. Shaaban , Samira Elaissi , Ilyas Khan , Rzgar Farooq Rashid , Abdullah A. Faqihi , Haitham M. Hadidi , Humaira Kanwal
{"title":"Scrutinization of radiation flow of trihybrid nanofluid with Cattaneo–Christov flux model and oxytactic and gyrotactic microbes: A biofuel applications","authors":"Munawar Abbas , Shaaban M. Shaaban , Samira Elaissi , Ilyas Khan , Rzgar Farooq Rashid , Abdullah A. Faqihi , Haitham M. Hadidi , Humaira Kanwal","doi":"10.1016/j.jrras.2025.101920","DOIUrl":"10.1016/j.jrras.2025.101920","url":null,"abstract":"<div><div>The Cattaneo-Christov flux model is used to investigate the effects of a heat source and thermal radiation on the Darcy-Forchheimer flow of an MHD trihybrid nanofluid containing motile gyrotactic and oxytactic microorganisms across three distinct geometries. The suggested model offers useful insights into improving heat and mass transfer processes in bio-convective systems, particularly for biofuel generation. The Cattaneo-Christov flow model, combined with oxytactic and gyrotactic microorganisms in a trihybrid nanofluid, can optimize heat management, improve microorganism dispersal, and increase response efficiency in bioreactors. This framework is applicable to enhanced biofuel processing, microbial cultivation, and thermal management systems, resulting in increased energy efficiency and sustainable fuel generation. The equations are resolved in MATLAB using the Bvp4c tool. The outcomes show that the flow to the cone has the highest mass and heat transmission. Furthermore, higher temperature and concentration relaxation parameter estimates in the Cattaneo-Christov theory increase the mass and heat transfer rates.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101920"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Ehab , Lina Sayed El-Ahll , Heba A. Saudi , Elsayed Salama
{"title":"Design and characterization of BaO-enriched borophosphate glasses for advanced gamma and neutron radiation shielding applications","authors":"Mohamed Ehab , Lina Sayed El-Ahll , Heba A. Saudi , Elsayed Salama","doi":"10.1016/j.jrras.2025.101899","DOIUrl":"10.1016/j.jrras.2025.101899","url":null,"abstract":"<div><div>Magnesium borophosphate glass composites with compositions <em>x</em>BaO–30MgO–10P<sub>2</sub>O<sub>5</sub>–(50–<em>x</em>)B<sub>2</sub>O<sub>3</sub>–10Na<sub>2</sub>O (<em>x</em> = 0, 1, 3, 10, 15, 20, 35 mol%) were synthesized via the melt-quenching method and evaluated for gamma and neutron radiation shielding. X-ray diffraction confirmed their amorphous nature, while density increased from 2.797 g cm<sup>−3</sup> (<em>x</em> = 0) to 3.938 g cm<sup>−3</sup> (<em>x</em> = 35) with BaO addition, accompanied by a reduction in molar volume. Gamma-ray attenuation studies over 0.015–15 MeV revealed that increasing BaO content enhanced the mass attenuation coefficient (μ<sub>m</sub>) and effective atomic number (Z<sub>e</sub>ff), with the 35 mol% BaO sample achieving the highest Z<sub>e</sub>ff (15.34) and lowest half-value layer (HVL) at all energies. At 0.662 MeV, μ<sub>m</sub> reached 0.0769 cm<sup>2</sup> g<sup>−1</sup> for <em>x</em> = 35, comparable to or exceeding values for barite concrete and similar glass systems. Exposure build-up factor (EBF) values decreased consistently with BaO enrichment, indicating improved photon shielding. For neutron interactions, the slow neutron cross-section (Σ<sub>s</sub>) decreased from 0.0646 cm<sup>−1</sup> (<em>x</em> = 0) to 0.0248 cm<sup>−1</sup> (<em>x</em> = 20) due to reduced boron content, while the fast neutron removal cross-section (Σᵣ) varied slightly from 0.1144 cm<sup>−1</sup> to 0.1012 cm<sup>−1</sup>. The trade-off in slow neutron attenuation is offset by the significant improvement in gamma-ray and fast neutron shielding. These results indicate that BaO-doped magnesium borophosphate glasses combine high gamma attenuation efficiency, structural compactness, and stable fast neutron performance, making them promising candidates for advanced medical, nuclear, and industrial radiation shielding applications.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101899"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hui Su , Hao Wang , Shuai Su , Yuan Liu , Zhitao Fan
{"title":"A predictive nursing model using CT perfusion imaging improves outcomes in acute cerebral hemorrhage","authors":"Hui Su , Hao Wang , Shuai Su , Yuan Liu , Zhitao Fan","doi":"10.1016/j.jrras.2025.101906","DOIUrl":"10.1016/j.jrras.2025.101906","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the impact of a predictive nursing model (CTP-PNM) based on CT perfusion imaging parameters compared to routine nursing (RN). Specifically, we assessed prognosis, neurological recovery, biochemical markers, symptom relief, quality of life, and complications in patients with acute cerebral hemorrhage (ACH).</div></div><div><h3>Methods</h3><div>A retrospective cohort study included 225 ACH patients (RN group: n = 121; CTP-PNM group: n = 104) treated between May 2021 and May 2023. The RN group received standard care. The CTP-PNM group received RN plus targeted interventions, such as intensified intracranial pressure (ICP) monitoring and anti-inflammatory measures, guided by individual CTP-defined risks. Baseline characteristics, biochemical markers, symptoms, neurological, cognitive, emotional, functional, and quality-of-life scales, overall treatment effectiveness, and complications were compared.</div></div><div><h3>Results</h3><div>Groups were comparable at baseline. After nursing, the CTP-PNM group demonstrated significant improvements across neurological function (e.g., NIHSS score), inflammatory markers, emotional state, and quality of life (all P < 0.05). CTP-PNM had higher total efficacy (P < 0.001) and significantly lower total complication rates (P = 0.016), particularly infections, deep vein thrombosis (DVT), pressure sores, and Gastrointestinal (GI) hemorrhage.</div></div><div><h3>Conclusion</h3><div>The CT perfusion parameter-based predictive nursing model represents a significant advance over routine care for ACH patients. It not only enhances neurological recovery, reduces inflammatory markers, alleviates symptoms, improves emotional state and quality of life but also increases overall treatment effectiveness and decreases complications. This approach has the potential to set a new standard for managing ACH patients.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101906"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144932375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mossad A. Salama , Korany A. Korany , Mohammed Ezzeldien
{"title":"Marble and granite as natural radiation sources: Risk assessment and their impact on health and the environment","authors":"Mossad A. Salama , Korany A. Korany , Mohammed Ezzeldien","doi":"10.1016/j.jrras.2025.101901","DOIUrl":"10.1016/j.jrras.2025.101901","url":null,"abstract":"<div><div>Driven by growing public health concerns and limited regional data, this study investigates natural radioactivity and associated radiological hazards in marble and granite widely used in Al-Jouf, Saudi Arabia. Twenty-eight marble and thirty granite samples were systematically collected and analyzed via gamma-ray spectrometry using a high-purity germanium (HPGe) detector. The mean activity concentrations (±SD) for marble were 14.82 ± 10.63 Bq/kg (<sup>226</sup>Ra), 16.54 ± 8.53 Bq/kg (<sup>232</sup>Th), and 78.61 ± 41.64 Bq/kg (<sup>40</sup>K). For granite, the values were 28.58 ± 19.89 Bq/kg, 37.04 ± 27.35 Bq/kg, and 960.48 ± 494.08 Bq/kg, respectively. Key hazard indices showed mean values for marble of radium equivalent activity (Ra<sub>eq</sub>) 38 ± 19.36 Bq/kg, external hazard index (H<sub>ex</sub>) 0.10 ± 0.05, internal hazard index (H<sub>in</sub>) 0.15 ± 0.07, and representative gamma index (I<sub>γ</sub>) 0.27 ± 0.13. For granite, the mean values were Ra<sub>eq</sub> 151.14 ± 92.75 Bq/kg, H<sub>ex</sub> 0.41 ± 0.25, H<sub>in</sub> 0.48 ± 0.3, and I<sub>γ</sub> 1.16 ± 0.7. The mean annual indoor effective dose equivalent (AEDE) was 0.087 ± 0.042 mSv/y for marble and 0.363 ± 0.219 mSv/y for granite—both below the public exposure limit of 1 mSv/y—although some granite samples exceeded the recommended gamma index threshold due to elevated potassium content. Most marble samples were deemed radiologically safe for construction, while certain granite varieties may require additional processing or regulatory oversight.</div><div>This work provides the first comprehensive radiological baseline for building stones in Al-Jouf, supporting material safety regulations and public health protection.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101901"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"α-MSH attenuates bleomycin-induced pulmonary fibrosis via NF-κB and inflammation suppression","authors":"Rui Xiao , Wei-Min Zhang , Hui-Ru Mai , Jin-Tian Zhou , Chun-Guang Xu","doi":"10.1016/j.jrras.2025.101917","DOIUrl":"10.1016/j.jrras.2025.101917","url":null,"abstract":"<div><h3>Objective</h3><div>Pulmonary fibrosis is a lung disease with high mortality and a lack of safe and effective treatments. α-MSH, a neuroimmunomodulatory peptide, has reported antifibrotic effects. This study aimed to study the mechanism by which α-MSH improves pulmonary fibrosis.</div></div><div><h3>Methods</h3><div>Macrophage and mouse pulmonary fibrosis models were established via bleomycin or LPS induction. In these models, inflammatory factor expression was detected via ELISA and qRT‒PCR, apoptosis levels were measured via flow cytometry, <em>α-SMA</em> and Collagen I expression were assessed via immunohistochemistry, and <em>NF-κB</em> activity was analyzed via Western blotting.</div></div><div><h3>Results</h3><div>LPS and bleomycin synergistically promoted macrophage secretion of <em>TNF-α</em>, <em>IL-1β</em>, <em>IFN-γ</em>, and <em>IL-10</em>, upregulated <em>CD14</em> expression, and increased cell apoptosis, whereas α-MSH treatment (100 nmol/L for 24 h) significantly inhibited these effects. In the mouse pulmonary fibrosis model (bleomycin or/and LPS treatment), <em>TNF-α</em>, <em>IL-1β</em>, <em>IFN-γ</em>, and <em>ELA2</em> levels were elevated in bronchoalveolar lavage fluid (BALF) and serum, while <em>TNF-α</em>, <em>IL-1β</em>, <em>IFN-γ</em>, <em>IL-10</em>, <em>α-SMA</em>, Collagen I, and <em>NF-κB</em> activity were upregulated in lung tissues. α-MSH treatment (50 μg/kg for 3 weeks) suppressed inflammatory factor secretion, reduced fibrosis-related factor expression, and decreased <em>NF-κB</em> activity.</div></div><div><h3>Conclusion</h3><div>α-MSH inhibits <em>NF-κB</em> activation and inflammation, thereby exerting antifibrotic effects. These findings support α-MSH as a promising therapeutic candidate for pulmonary fibrosis.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101917"},"PeriodicalIF":2.5,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144919909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M.A.M. Uosif , A.M.A. Mostafa , Reda Elsaman , Hani Negm , A. Atta , Nomery Hadia , E.F. El Agammy , Ahmed A. Abdelrhman , Yasser A. Sayed , Ahmed I. El-Desoky , Elsayed Abdelbaky
{"title":"Evaluation of radioactivity in the newly reclaimed soils and its association with soil properties","authors":"M.A.M. Uosif , A.M.A. Mostafa , Reda Elsaman , Hani Negm , A. Atta , Nomery Hadia , E.F. El Agammy , Ahmed A. Abdelrhman , Yasser A. Sayed , Ahmed I. El-Desoky , Elsayed Abdelbaky","doi":"10.1016/j.jrras.2025.101885","DOIUrl":"10.1016/j.jrras.2025.101885","url":null,"abstract":"<div><div>The newly reclaimed soil has poor agricultural fertility in addition to being contaminated by excessive use of fertilizer, improper irrigation practices, and poor irrigation water quality. The radioactivity of farming soil and the radiological health risks to farm people in Qena Governorate, Egypt, were evaluated using natural radionuclide measurements (<sup>226</sup>Ra, <sup>232</sup>Th and <sup>40</sup>K) from surface and subsurface soil samples collected in 15 locations. Both bivariate and multivariate statistics to investigate associations between radioactivity concentration and soil physicochemical properties. The findings indicate that the mean value for <sup>226</sup>Ra, <sup>232</sup>Th, and <sup>40</sup>K range from 5 ± 0.20 to 14 ± 0.7, 3 ± 0.20 to 14 ± 0.70, and 11 ± 0.50 to 72 ± 3.60 Bq Kg<sup>−1</sup>, respectively. These results were compared to data reported from other countries and the global average. The concentrations of <sup>226</sup>Ra, <sup>232</sup>Th, and <sup>40</sup>K were found to be lower than the global average. Additionally, all samples underwent analysis for radium equivalent, absorbed gamma dose rate, annual effective dose, internal hazard index, external hazard index, gamma radiation hazard index, and excess lifetime cancer risk. The results of PCA analysis indicate that soil management practices and soil reclamation activities have an impact on the radioactivity level and distribution. Furthermore, physical, and chemical characteristics of the soil, especially texture, pH, and calcium carbonate, were revealed to be the primary determinants of radioactive concentrations in the soil, according to PCA and Pearson correlation analysis. The data will establish the initial concentration of naturally occurring radionuclides in the research area, providing valuable information for monitoring and evaluating potential environmental contamination within this locality.</div></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"18 4","pages":"Article 101885"},"PeriodicalIF":2.5,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}