Journal of Plastic Surgery and Hand Surgery最新文献

{"title":"Clinical efficacy of titanium elastic nail fixation for the treatment of pediatric limb fractures and its impact on postoperative bone mineral density and bone metabolism levels.","authors":"Zhanhui Zhou, Donger Hai, Xiaoliang Chen, Peng Liu","doi":"10.2340/jphs.v61.46896","DOIUrl":"https://doi.org/10.2340/jphs.v61.46896","url":null,"abstract":"<p><strong>Objective: </strong>This study was designed to examine the clinical efficacy of titanium elastic nail (TEN) fixation in treating pediatric long bone fractures of the limbs and its impact on bone mineral density (BMD) and bone metabolism.</p><p><strong>Methods: </strong>Sixty children with long bone fractures of the limbs were divided into the control group (underwent open reduction and internal fixation with a plate) and the observation group (received TEN fixation) (n = 30 each group). Surgical indicators (operative time, intraoperative blood loss, fracture healing time, and hospital stay), fracture healing excellence rate, complication incidence, and overall clinical effectiveness were compared. BMD, serum basic fibroblast growth factor (bFGF), total type I collagen N-terminal propeptide (TPINP) levels, the Hospital for Special Surgery (HSS) knee function score, Harris hip function score, and Mayo Elbow Performance Score (MEPS) were assessed.</p><p><strong>Results: </strong>The observation group exhibited superior surgical indicators, higher fracture healing excellence rate, overall clinical effectiveness, and lower complication incidence than controls (all p < 0.05). At 3 months postoperatively, BMD and bFGF had increased, and TPINP had decreased compared to preoperative values in both cohorts, with the observation group showing higher/lower measures (all p < 0.05). At 6 months postoperatively, the observation group achieved higher HSS, Harris, and MEPS scores compared with the control group (all p < 0.05).</p><p><strong>Conclusion: </strong>TEN fixation accelerates fracture healing, reduces complications, improves BMD and bone metabolism, and restores joint function in children with long bone fractures of the limbs.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"257-262"},"PeriodicalIF":1.4,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified non-transarticular K-wire external fixation versus traditional transarticular pinning for bony mallet finger: a prospective comparative cohort study.","authors":"Weigang Zhu, Jiashi Song, Haibo Zhou, Huaguo Tang, Jingjing Bao, Yuanjie Gu","doi":"10.2340/jphs.v61.46985","DOIUrl":"https://doi.org/10.2340/jphs.v61.46985","url":null,"abstract":"<p><strong>Background: </strong>Traditional transarticular distal interphalangeal joint (DIPJ) pinning for bony mallet fingers risks stiffness and iatrogenic cartilage injury. This study compared a modified non-transarticular K-wire external fixator with traditional transarticular pinning for surgically treated bony mallet finger.</p><p><strong>Methods: </strong>This single-center prospective nonrandomized comparative cohort study included 120 adults with acute bony mallet finger. Sixty patients underwent traditional transarticular DIPJ pinning, and 60 underwent modified non-transarticular K-wire external fixation. The primary outcome was overall postoperative complications, including pin tract infection, joint stiffness, loss of reduction, nail deformity, or radiographic degenerative change assessed at 1 year. Secondary outcomes included operative time, hardware removal time, bone union time, DIPJ motion, Crawford grade, pain, QuickDASH score, and return-to-work time. Logistic regression was used to identify predictors of overall complications.</p><p><strong>Results: </strong>Baseline demographic and injury characteristics were comparable between groups. Overall complications were significantly less frequent after modified fixation than after traditional fixation (15.0% vs 48.3%, p < 0.001). The modified technique markedly reduced joint stiffness and nail deformity. It was also associated with shorter operative time, earlier hardware removal, faster bone union, lower extension lag, greater maximum DIPJ flexion, better Crawford grade distribution, lower pain and QuickDASH scores, and earlier return to work. In multivariable analysis, traditional fixation remained independently associated with higher complication risk.</p><p><strong>Conclusion: </strong>Modified non-transarticular K-wire external fixation was associated with fewer complications and better early functional recovery than traditional transarticular DIPJ pinning. This joint-sparing, low-cost technique may be a useful surgical option for selected patients with bony mallet finger.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"263-269"},"PeriodicalIF":1.4,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between functional prognosis in patients with infection after upper limb trauma: a predictive model based on HbA1c stratification and the mediating role of delayed rehabilitation.","authors":"Sheng Chen, YiFei Zhu, MinTao Tian, HongLei Hu, Lu Xu, BiYun Li","doi":"10.2340/jphs.v61.46666","DOIUrl":"https://doi.org/10.2340/jphs.v61.46666","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between preoperative glycated hemoglobin (HbA1c) and upper limb function (Disabilities of the Arm, Shoulder and Hand [DASH] score) at 6 months post-surgery in patients with fracture-related infection (FRI) after upper limb trauma, and to test the mediating role of rehabilitation initiation time.</p><p><strong>Methods: </strong>This retrospective cohort study included 100 patients with FRIs after upper limb trauma surgery (September 2020 to August 2025). Demographic characteristics, fracture features, HbA1c levels, time to initiate rehabilitation, and debridement frequency of patients were collected. With the DASH score at 6 months after surgery as the outcome variable, multiple linear regression was used to analyze the association between HbA1c and functional prognosis, and the Bootstrap method was used to test the mediating effect of rehabilitation initiation time.</p><p><strong>Results: </strong>HbA1c was significantly positively correlated with the DASH score (β = 6.90, 95% CI 3.91-9.89, p < 0.001). Recovery initiation time played a partial mediating role between the HbA1c and the DASH scores, with a mediating ratio of 27% (indirect effect 2.04, 95% CI 0.63-3.59, p = 0.004). There was no significant interaction between HbA1c and recovery initiation time or debridement frequency (p > 0.05). Thresholding effect analysis did not find a definite breakpoint (log-likelihood ratio test p = 0.220), and HbA1c was linearly related to the DASH score.</p><p><strong>Conclusion: </strong>Preoperative HbA1c is independently associated with 6-month upper limb function in patients with post-traumatic infection, with rehabilitation initiation time playing a partial mediating role. Clinicians should prioritize glycemic control and initiate rehabilitation as early as safely possible.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"249-256"},"PeriodicalIF":1.4,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-specific implants are accurate and cost-effective for blow-out fracture reconstruction: a retrospective case-control study.","authors":"Eeva Kormi, Ville Männistö, Pilvi Mäntynen, Niilo Lusila, Juho Suojanen","doi":"10.2340/jphs.v61.46676","DOIUrl":"https://doi.org/10.2340/jphs.v61.46676","url":null,"abstract":"<p><strong>Background: </strong>The volume of the bony orbit increases in facial trauma with a blow-out fracture and may lead to enophthalmos and double vision. The orbit's volume can be restored surgically. The authors aimed to determine the most accurate and cost-effective method for reconstructing blow-out fractures: virtual surgical planning (VSP) combined with patient-specific implants (PSI) or standard titanium stock implants.</p><p><strong>Materials and methods: </strong>The authors conducted a retrospective study of patients who sustained a blow-out fracture requiring surgical reconstruction. Patients were categorized into two groups: the PSI group (n = 13) and the standard titanium stock implant group (n = 36). The primary aim was to analyze the total cost in each group, with a secondary aim to ensure volumetric restoration was achieved. Postoperative volume, operation time, need for reoperation, surgical and inpatient costs, and cost-effectiveness were calculated. The data were analyzed with Shapiro-Wilk, Mann-Whitney U test, and Fisher's exact test, using a significance level of 0.05.</p><p><strong>Results: </strong>The operation time was significantly shorter in the PSI group than in the stock implant group, with an average of 89.77 and 122.69 min, respectively (p = 0.008), resulting in lower total costs in the PSI group. The PSI group had better postoperative volumetric restoration than the stock implant group compared to the contralateral side (p = 0.01). Four out of 36 patients (11%) needed reoperation in the stock implant group.</p><p><strong>Conclusions: </strong>Preliminary results suggest that PSI requires a shorter operation time and is therefore cost-effective without compromising surgical outcomes.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"243-248"},"PeriodicalIF":1.4,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suturing and knot-tying techniques in microsurgery: anastomosis time, learning curve and scanning electron microscopic assessment.","authors":"Çağhan Benli, Mustafa Akyürek","doi":"10.2340/jphs.v61.46794","DOIUrl":"https://doi.org/10.2340/jphs.v61.46794","url":null,"abstract":"<p><strong>Background: </strong>Various suturing and knotting techniques exist to enhance microsurgical efficiency, yet a comprehensive comparison is lacking. This study evaluates two suturing (interrupted vs. open-loop) and two knot-tying (conventional vs. airborne) techniques to determine how anastomosis time is apportioned between them.</p><p><strong>Methods: </strong>Seventy-two femoral artery anastomoses were performed on 36 female Wistar-albino rats by nine microsurgeons, stratified into three groups (<1, 1-4, >4 years experience). The four combinations were interrupted or open-loop suture with conventional or airborne knot (IS-CK, IS-AK, OLS-CK, OLS-AK). Each surgeon performed all four before and after a standardised practice session, making technique and practice within-subject factors and experience a between-subject factor, analysed by split-plot repeated-measures ANOVA. Twelve anastomoses from the most experienced group were examined by scanning electron microscopy (SEM), blind to technique and operator.</p><p><strong>Results: </strong>The knot-tying method, rather than the suturing technique, was the principal factor associated with anastomosis time. Conventional knotting was approximately 11 min faster than airborne knotting (666 s; p < 0.001), whereas the two suturing techniques differed by 18.6 s within conventional knotting (p = 0.46) and 82.3 s within airborne knotting (p = 0.005) - approximately 1% and 4% of total time. Experience dominated (51.2 vs. 13.3 min; 3.85-fold; p < 0.001). All techniques improved after practice, and the improvement depended on the technique (F(3,18) = 8.30, p = 0.001): approximately 15% for the airborne-knot techniques vs. 5-10% for the conventional-knot techniques. SEM showed a dissociation: suture spacing was determined by the suturing technique (open-loop superior, p = 0.001) and knot quality by the knot-tying technique (airborne superior, p < 0.001); neither affected suture-tissue interaction (p = 0.77).</p><p><strong>Conclusion: </strong>In elective, uncomplicated anastomoses the knot-tying technique, rather than the suturing technique, was most strongly associated with anastomosis time, while surgical experience outweighed both. The airborne knot costs approximately 11 min but yields better knot quality and improves most with practice; the open-loop suture gives more regular suture spacing at negligible time cost. Technique selection is therefore a trade-off between ischaemia time and technical refinement, informed primarily by the operator's experience. Grant sponsor: Çanakkale Onsekiz Mart University Scientific Research Projects Coordination Unit. Grant number: TTU-2024-4668.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"229-236"},"PeriodicalIF":1.4,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of patient and surgical factors on prognosis in repeated flexor tenorrhaphy.","authors":"Jong Ju Park, Si Young Roh, Sung Hoon Koh, Dong Chul Lee, Jin Soo Kim, Kyung Jin Lee","doi":"10.2340/jphs.v61.46464","DOIUrl":"https://doi.org/10.2340/jphs.v61.46464","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate factors influencing outcome in patients who experienced re-rupture after flexor tenorrhaphy.</p><p><strong>Background: </strong>Flexor tendon re-rupture following tenorrhaphy remains a significant complication that can adversely affect functional outcomes and require repeated surgical intervention. This study aimed to investigate factors influencing prognosis in patients who experienced re-rupture after flexor tenorrhaphy.</p><p><strong>Materials and methods: </strong>We retrospectively analyzed patients who underwent flexor tendon tenorrhaphy on little fingers between January 2011 and September 2024 and subsequently experienced re-rupture -followed by a primary repair. We analyzed factors such as re-rupture timing, rupture to surgery interval, patient demographics, medical history, and participation in rehabilitation therapy using a simple linear regression model. Patients with underlying diseases, concurrent fractures, thumb or extensor tendon ruptures, or follow-up periods less than 6 months were excluded. The Adjusted Strickland and Whitaker methods were used for evaluation.</p><p><strong>Results: </strong>A total of 17 patients out of 313 who underwent flexor tendon repair experienced re-rupture and met the inclusion criteria. Age and re-rupture period significantly affected prognosis. Older patients showed poorer final range of motion outcomes. In contrast, the initiation date, frequency, and duration of rehabilitation therapy did not demonstrate statistically significant correlations with prognosis.</p><p><strong>Conclusions: </strong>Older age and delayed re-rupture were associated with poorer postoperative finger range of motion following repeated flexor tenorrhaphy. Therefore, patients should be advised to avoid excessive hand use until adequate tendon healing is achieved, and thorough postoperative education may be particularly important in elderly patients.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"237-242"},"PeriodicalIF":1.4,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of a defect-adapted strategy for free fibular great toe flaps in finger reconstruction: a retrospective series of 35 cases.","authors":"Yangyang Liu, Huajian Zhou, Haoran Jiang, Jun Zhu, Renjie Li, Mingyu Jia","doi":"10.2340/jphs.v61.46668","DOIUrl":"https://doi.org/10.2340/jphs.v61.46668","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the clinical outcomes of a personalized surgical strategy for small-to-medium finger defects, utilizing either free dorsal toe or plantar proper digital artery flaps.</p><p><strong>Methods: </strong>We retrospectively analyzed 35 patients with finger defects (March 2021-January 2025). Patients were assigned by defect characteristics to Group A (pulp defects, n = 21; plantar proper digital artery flap) or Group B (dorsal/lateral defects, n = 14; modified dorsal toe artery flap preserving the plantar proper neurovascular bundle). We evaluated operative time, flap survival, Disabilities of the Arm, Shoulder and Hand (DASH), Michigan Hand Outcomes Questionnaire (MHQ), static two-point discrimination (s2PD), and American Orthopaedic Foot & Ankle Society (AOFAS) scores.</p><p><strong>Results: </strong>All 35 flaps survived. Group B had a significantly shorter mean operative time than Group A (124.00 ± 6.42 vs. 146.57 ± 9.61 minutes, p < 0.001). At final follow-up (6-13 months), Group B exhibited slightly better hand function (DASH: 5.89 ± 0.52 vs. 7.17 ± 1.00, p < 0.001; MHQ: 86.89 ± 2.82 vs. 83.61 ± 4.39, p = 0.018). Conversely, Group A achieved superior sensory recovery (s2PD: 7.48 ± 0.93 vs. 8.71 ± 0.83 mm, p < 0.001). Group B showed superior donor-site preservation without painful calluses (AOFAS: 96.08 ± 1.44 vs. 84.31 ± 2.19, p < 0.001).</p><p><strong>Conclusions: </strong>A tailored approach to donor vessel selection reliably guides personalized finger reconstruction. The plantar proper system optimizes pulp reconstruction for superior sensory recovery, whereas the modified dorsal system suits dorsal/lateral defects by minimizing operative time and maximizing donor-site protection.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"224-228"},"PeriodicalIF":1.4,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148829587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with anxiety and depression following acute hand trauma: a prospective study of 134 patients.","authors":"Ozer Ozmut, Arslan Guvendik, Abdullah Bugra Kaya, Burak Yasar, Hasan Murat Ergani, Ramazan Erkin Unlu","doi":"10.2340/jphs.v61.46667","DOIUrl":"https://doi.org/10.2340/jphs.v61.46667","url":null,"abstract":"<p><strong>Introduction: </strong>Acute hand trauma is frequently accompanied by psychological distress; however, the demographic and injury-related factors associated with this response remain poorly understood. This study aimed to identify factors associated with early psychological distress in patients with acute hand trauma.</p><p><strong>Methods: </strong>We prospectively evaluated 134 adult patients presenting with acute hand trauma. Patients completed the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI), and psychiatric symptoms were additionally assessed by a psychiatrist using the Brief Psychiatric Rating Scale (BPRS). Demographic characteristics, psychiatric history, pain scores, injury characteristics, and structural injuries were recorded. Multivariable linear regression analysis was performed to identify independent factors associated with psychological distress.</p><p><strong>Results: </strong>Anxiety symptoms were the most common psychological manifestation, affecting 44% of patients. Previous psychiatric history, nerve injury, and work-related injury were independently associated with higher psychological distress scores. Younger age and female sex showed associations in univariable analyses but were not independent predictors after multivariable adjustment.</p><p><strong>Conclusion: </strong>Early psychological distress following acute hand trauma appears to be influenced primarily by patient-related factors and nerve injury rather than anatomical injury level alone. Early psychological screening should be considered, particularly for patients with a previous psychiatric history or concomitant nerve injury.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"218-223"},"PeriodicalIF":1.4,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148813446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LMWH prophylaxis after digital replantation and early vascular compromise.","authors":"Xiaoyu Li, Ting Liu, Feng Gu, En Wu, Yun Cao, Jishuang Guan, Jiaxing Fan, Qiang Wang, Yonghui Liang","doi":"10.2340/jphs.v61.46664","DOIUrl":"https://doi.org/10.2340/jphs.v61.46664","url":null,"abstract":"<p><strong>Background: </strong>Early vascular compromise remains a major cause of failure after digital replantation, and the optimal low-molecular-weight heparin (LMWH) regimen remains unclear. This study compared intensified versus standard LMWH prophylaxis for preventing early vascular compromise after digital replantation.</p><p><strong>Materials and methods: </strong>In this single-center retrospective cohort study, consecutive adult patients undergoing digital replantation (2023-2025) were included. All procedures were performed by one microsurgeon. Postoperative LMWH was administered subcutaneously for 7 days as either 5000 international units once daily (QD) or twice daily (BID), according to a preexisting department protocol. The primary endpoint was a composite of early vascular compromise, including vascular crisis, re-exploration, therapeutic bloodletting/leech therapy, or digit failure.</p><p><strong>Results: </strong>Sixty-nine patients (85 digits) were included (QD: 39 patients; BID: 30 patients). The primary endpoint occurred in 12/39 patients in the QD group versus 1/30 in the BID group. All vascular crises were venous. Digit failure occurred in 5 QD patients, and none in the BID group. No bleeding or transfusion events were observed.</p><p><strong>Conclusions: </strong>Twice-daily LMWH prophylaxis was associated with fewer early vascular compromise events after digital replantation compared with once-daily dosing. These findings are hypothesis-generating and require prospective validation.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"212-217"},"PeriodicalIF":1.4,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cleft types, lower-lip pits, and lip pit surgeries in individuals with Van der Woude syndrome in Finland.","authors":"Emma Juuri, Charlotta Gustafsson-Silén, Arja Heliövaara","doi":"10.2340/jphs.v61.46485","DOIUrl":"10.2340/jphs.v61.46485","url":null,"abstract":"<p><strong>Background: </strong>Van der Woude syndrome (VWS) may display varied clinical features. We aimed to determine cleft types, lower lip pits, and lip pit surgeries in a large VWS cohort in Finland.</p><p><strong>Materials and methods: </strong>This is a single-center retrospective, observational patient record study performed at national centralized cleft center that evaluated 151 individuals with VWS born between 1946 and 2019. Information regarding sex, cleft type, lip pit presence, and the number of lip pit surgeries were gathered from patient records.</p><p><strong>Results: </strong>Sixty per cent of the individuals with VWS were female and 40% were male (p < 0.01). The majority (105/151; 70%) of the individuals with VWS presented with clefts in the palate region (p < 0.01). Cleft lip (CL) occurred in 7.3% and cleft lip and palate (CLP) in 21.5% and no cleft in 2.6% of individuals with VWS. Information on lip pits was available for 127/151 patients. Lip pits were present in 93% of patients. Lip pits were surgically removed more frequently in unilateral cleft lip and palate (UCLP) (84.6%) and bilateral cleft lip and palate (BCLP) (66.7%) compared with cleft palate (CP) (8.8%) (p < 0.001). Recurrent surgery for lip pits occurred more often in BCLP (46.4%) than in UCLP (6.7%) and CP (1.3%).</p><p><strong>Conclusions: </strong>In Finland, cleft palate is the predominant cleft type in VWS. Cleft type distribution in VWS reflects the frequencies of non-syndromic clefts in Finland, deviating from trends observed in other countries. Lip pits are more commonly removed in UCLP or BCLP than in CP only. Furthermore, recurrent surgeries for lip pits occur more frequently in individuals with BCLP.</p>","PeriodicalId":16847,"journal":{"name":"Journal of Plastic Surgery and Hand Surgery","volume":"61 ","pages":"207-211"},"PeriodicalIF":1.4,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148706863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}