Journal of Nutrition and Food Sciences最新文献

{"title":"Targeting Cannabinoid Receptors and Fatty Acid Amide Hydrolase: An Innovative Food-Grade Delivery System of Zingiber officinale and Acmella oleracea Extracts as Natural Adjuvant in Pain Management","authors":"G. Petrangolini, F. Donzelli, Davide Berl, P. Allegrini, A. Rossignoli, M. Stucchi, A. Riva","doi":"10.35248/2155-9600.20.10.766","DOIUrl":"https://doi.org/10.35248/2155-9600.20.10.766","url":null,"abstract":"Background: Anti-inflammatory and analgesic properties are displayed by several natural products, in particular Acmella oleracea and Zingiber officinale. Literature data suggests that both botanical extracts can be useful as inflammation/pain modulators, so technological efforts have been made to associate them together in a unique delivery new food-grade formulation, Mitidol, with the purpose of improving their beneficial effects. Objective: The aim of the present work was to assess if Mitidol and its active ingredients are able to modulate the endocannabinoid 2 receptor system, one of the major systems responsible for positive effects of Cannabis treatment. Cannabinoid 2 receptor represents an attractive pharmacological target in obtaining an anti-inflammatory/analgesic effect with low central nervous system side-effects. Methods: The new food-grade Phytosome, together with all the botanical ingredients and active compounds, were tested in a cell-based assay in human recombinant Cannabinoid 2 Receptor cells, in order to evaluate a possible agonist effect on those receptors, and in a Fatty Acid Amide Hydrolase Inhibition Activity assay, to evaluate potential inhibition of that hydrolase, which is responsible for degradation of the endogenous cannabinoid anandamide. Results: Zingiber officinale showed potent activity in Fatty Acid Amide Hydrolase Inhibition Activity assay, being about six fold more effective than the flavonoid Kaempferol. Acmella oleracea proved to be highly active in Fatty Acid Amide Hydrolase inhibition and Cannabinoid 2 activation. Conclusion: Our data suggest a strong rationale for the use of Mitidol as a natural adjuvant in pain management.","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"26 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83275071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diet Oriented Safety of Pakistani Biryani with reference to Glycemic Response in Healthy Human Subjects","authors":"Asif Ahmed, S. Ahmed, S. Sadiq, L. Farooq, H. Arif, Sumreen Mujahid","doi":"10.35248/2155-9600.20.10.768","DOIUrl":"https://doi.org/10.35248/2155-9600.20.10.768","url":null,"abstract":"Introduction: Traditional Pakistani Biryani is popular food particularly among Asian population. The objective of this study was to evaluate glycemic response of compound test food in conjunction with Food Oriented Diet Safety in healthy human subjects. Material and methods: This Quasi-Interventional Study was conducted in research unit of Baqai medical university. This study was conducted in period of two days and twenty healthy volunteers were enrolled. On day 1; fasting blood sugars were checked. Subsequently on day 2 participants were instructed to report with 12 hr. fasting, Later Compound test food was offered according to Health Body Mass Index (BMI) and Calories Calculator. Sequential plasma glycemic response was recorded on 0, 30, 60, 90 and 120 minutes. Results: Day 1, Glycemic response of study subjects showed mean glycemic value of 104 mg/dl. Day 2, glycemic response of 0, 30, 60, 90 and 120 minutes showed of 118,130, 121,109, 106 mg/dl respectively. This study highlights desirable incremental and decremented glycemic response after 30 & 120 mins respectively. Conclusion: This study concludes; that consumption of tested compound food according to BMI expected to have physiological mean peak glycemic response. Therefore this study identifies that consumption of beef biryani is safe; as study population never showed abnormal mean glycemic peak.","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"14 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90561117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Chronic Supplementation with Nitrate-Rich Beetroot Juice on Cardiovascular Responses in Healthy Adults","authors":"Stanaway, Rutherfurd-Markwick, Patrice A. Reid, Wong, Jones, Ali","doi":"10.3390/proceedings2019037027","DOIUrl":"https://doi.org/10.3390/proceedings2019037027","url":null,"abstract":"Acute and short-term supplementation with nitrate-rich (NO3−) beetroot juice has been shownto improve cardiovascular health and function in healthy adults [...]","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"7 1","pages":"27"},"PeriodicalIF":0.0,"publicationDate":"2019-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78992057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beneficial Effects Of Thymoquinone On Metabolic Function And Fatty Liver In A Murine Model Of Obesity","authors":"M. Licari, Marco Raffaele, Z. Rosman, J. Schragenheim, L. Bellner, L. Vanella, R. Rezzani, L. Rodella, F. Bonomini, E. Hochhauser, M. Arad, N. Abraham","doi":"10.35248/2155-9600.19.9.751","DOIUrl":"https://doi.org/10.35248/2155-9600.19.9.751","url":null,"abstract":"Aim: Nigella sativa seeds contain a high amount of Thymoquinone (TQ), an antioxidant. We therefore hypothesized that Nigella sativa oil would, through the antioxidant properties of TQ ameliorate obesity-induced hyperglycemia and decrease blood pressure and OX-LDL in obese mice. Methods: Commencing at eight weeks of age, C57B16 male mice were fed a high fat diet (HF) for 20 weeks. Mice were divided into three groups of five animals each as follows: group 1) Lean, group 2) HF diet, group 3) HF diet treated for the last 8 weeks with 3%TQ. Inflammatory biomarkers, antioxidant biomarkers, mitochondrial biogenesis and tissue fat accumulation and hepatic steatosis were determined. Results: 3% TQ treatment resulted in an increase of oxygen consumption decreased fasting glucose and blood pressure (P<0.05) as compared in obese mice. TQ treatment increased both the quantity of hepatic HO-1, and HO activity in response to 3% TQ. Additionally, mitochondrial Mfn2, PGC1α, insulin receptor phosphorylation in response to TQ while decreased LDL and OX-LDL (P<0.05) and haptic lipid accumulation. Conclusion: Fundamentally, TQ intervention attenuated the obesity-mediated decrease of oxygen consumption, fasting glucose, improved mitochondrial biogenesis through an increase and in levels of HO-1 that is associated with ablated HF-induced LDL. Our findings indicate a potential clinical role for TQ in the prevention of obesity-related steatosis in metabolic disease.","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"178 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79960042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunoassay Platform for Casein Antigens in Hydrolyzed Casein-Based Infant Formula","authors":"Chris Butler, M. Miklus, C. Barber, S. Tennyson, P. Prieto","doi":"10.4172/2155-9600.1000753","DOIUrl":"https://doi.org/10.4172/2155-9600.1000753","url":null,"abstract":"Hypoallergenic formulas are the sole source of nutrition for infants that are either allergic to milk proteins or at risk of developing allergies. Strategies to provide nutritional sustenance, while preventing allergic reactions, include designing formulas based on extensively hydrolyzed casein which is presumably devoid of antigenic epitopes. Assays devoted to the assessment of antigenic protein motifs are crucial to verify the absence of relevant antigens in formulas and the raw materials used in their preparation. Evaluation of commercial immunoassay kits intended for the detection of milk proteins in foods led to the conclusion that a specific assay for extensively hydrolyzed casein-based formulas was necessary to improve allergen recoveries and assay consistency. The purpose of this investigation was to develop a reproducible path, from the generation of antibodies to the pre-validation of immunoassays optimized for the analysis of hydrolyzed casein-based infant formula. We prepared purified antisera from sheep immunized with bovine acid-precipitated casein to establish a platform consisting of a slot blot immunoassay and an enzyme-linked immunosorbent assay. Results indicate that sheep can reliably produce antibodies against epitopes in the casein fraction of bovine milk, thus providing a quantitative reagent that binds to immobilized casein in different formats. The limits of detection and quantitation for standard solutions for the enzyme-linked immunoassay were 0.8 and 2.5 ppm, respectively. The limit of detection in the extensively hydrolyzed casein-based formula was 0.5 ppm and the limit of quantitation 1.4 ppm. This account describes two reproducible immunoassays that are accessible to any laboratory or manufacturing setting and do not require proprietary ingredients or undisclosed extraction solutions. While these tests were developed to quantitate casein in hypoallergenic formula matrices, an application of the slot blot immunoassay to assess residual casein on manufacturing surfaces is also described in the present account.","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"56 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90897893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthropometric Assessment of Adolescent Nutritional Status in Two Drought-Prone Areas of Ethiopia","authors":"S. Beyene, M. Willis, M. Mamo, B. Legesse, Teshome Regassa, T. Tadesse, Y. Wolde-hawariat","doi":"10.4172/2155-9600.1000755","DOIUrl":"https://doi.org/10.4172/2155-9600.1000755","url":null,"abstract":"Objective: The aim of this study was to assess the prevalence of undernutrition and associated factors among adolescents in two food insecure zones in Ethiopia. Methods: Data were collected through a survey of 350 rural households from five districts using a multistage sampling design. Demographic, socioeconomic, and anthropometric measurements were collected from 1437 individuals. The nutritional status of a subset of this sample, adolescents aged 10 to 19 years, was analyzed using the World Health Organization (WHO) AnthroPlus software. Height-for-age Z-score (HAZ), and BMI-for-age Z-score (BAZ) were calculated to determine nutritional status. Results: The prevalence of stunting (HAZ less than -2 standard deviations (SDs)) and thinness (BAZ < -2 SDs) were 18.4% and 15.0% respectively. Although these values are high by international standards, adolescents from the study population have relatively low rates of undernutrition compared to younger children from the same communities. Overall, undernutrition among adolescents was negatively associated with household access to irrigation and livestock holdings, but not with household size, farmland size or agroecology. Conclusion: Expanding access to nutrition-sensitive small-scale irrigation, and enhancing asset-building interventions, may contribute to the reduction of adolescent undernutrition in regions susceptible to climate change.","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"20 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83288379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of Escherichia coli, Salmonella spp. and Staphylococcus aureus in Ready-to-Eat Food in Al-Ahsa Province, Saudi Arabia","authors":"Al-Humam Na","doi":"10.35248/2155-9600.19.9.754","DOIUrl":"https://doi.org/10.35248/2155-9600.19.9.754","url":null,"abstract":"The study aimed to identify and characterize foodborne- Staphylococcus aureus, Escherichia coli and Salmonella spp. in Al-Ahsa Province, Kingdom of Saudi Arabia (KSA), as potential reservoir of human infection and transmitters of antimicrobial resistance. A total of 90 sandwich samples (consist of minced meat and vegetables) were aseptically collected from fast-food cafeterias. Conventional bacteriological techniques were used to isolate Staph aureus, E. coli and Salmonella spp. For E. coli isolates, molecular analysis was made. Staph aureus was confirmed from 11.11% of specimens of which 30% were MRSA. MRSA were resistant to erythromycin, nitrofurantoin and Trimethoprim/ Sulfamethoxazole. Non-MRSA were resistant to ciprofloxacin and all Staph aureus isolates were sensitive to vancomycin which may be a choice for treatment. At a rate of 5.56%, E. coli was confirmed by conventional techniques and VITEK 2 system; E. coli strain O157: H7 was not identified from the isolates. Molecular analysis indicated that 4 strains belonged to Shiga toxigenic E. coli (STEC) family and one strain was Shigella flexneri. Antimicrobial susceptibility analysis of isolates showed two strains (40%) were extended-spectrum β-lactamases (ESBL) positive that were demonstrated to be susceptible to imipenem but resistant to ciprofloxacin. On the other hand, three strains (60%) were identified as ESBL negative which were susceptible to all tested antibiotics. Salmonella spp. were not isolated from any food specimen in the present study. From ready-to-eat food in Al-Ahsa Province, KSA, Staph aureus MRSA and Non-MRSA were susceptible to vancomycin. Using molecular methods, E. coli and Shig. flexneri were confirmed from food with ESBL positive susceptible to imipenem but resistant to ciprofloxacin.","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"63 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80127516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short and Long Term Benefits from Consuming Nutrient-Dense Foods","authors":"S. Bell, Peter M Castleman, Charles Marsl","doi":"10.4172/2155-9600.1000752","DOIUrl":"https://doi.org/10.4172/2155-9600.1000752","url":null,"abstract":"It is critical for companies that sell products affecting health and wellbeing to regularly ask their customers how effective their offerings are. In 2017, Nutrient (hereafter referred to as The Company), which manufactures healthy, nutrient-dense foods, conducted such an audit, in which it asked its customers how its products affected health and wellbeing. After a couple of months using The Company’s foods, the customers reported having more energy, losing weight, feeling fuller, being more focused and alert and less moody, and having improved health. The purpose of this current study was to confirm these findings in two cohorts: (1) Year-long customers: a sub-set of the 2017 data set who have been consuming the nutrient-dense foods for at least one year; and (2) Six-month customers: customers who placed at least one food order over a six-month span. The same ten questions were asked of each group and probed areas of wellbeing (e.g., energy, mood, focus) and health (e.g., stronger body, improved health). The responses were: Yes, No, or Not Applicable. Results for each question were presented as: % Yeses (number of Yeses/ sum of the total number of Yeses + number of Nos x 100). Those responding to the audit were shipped enough of The Company’s foods to average one serving daily in each of the six months of the audit. All percentage Yeses exceeded 80%, except for the Improved mood (73%) in the Year-Long customer group. The percentage of Yes responses were similar between the Year-long customers and Six-month customers. The percentage of Yeses differed by no more than 6 percentage points between the two groups, except for Improved mood (73% Yeses for the Year-long customers and 85% for the Six-month customers; 12-point difference). The questions that had the highest percentage of Yeses (>90%) in both the Year-long and New customer groups were Fullness and satisfaction and Improved health. In summary, the present findings support The Company’s 2017 audit, showing that consuming nutrient-dense foods leads to better health and wellbeing beyond nourishment after a couple of months of use and that the benefits extend beyond one year. Each answer to the audit questions exceeded 80% Yeses except one. The best responses in both groups related to feeling full and satisfied and having improved health. These findings support the notion that eating one of The Company’s nutrient-dense food daily makes one feel better and improves health.","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"57 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84866262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in post-operative bowel function and ileus between right and left-sided radical colorectal resections","authors":"Ben Liu, K. Thane, E. Jones","doi":"10.4172/2155-9600-C9-078","DOIUrl":"https://doi.org/10.4172/2155-9600-C9-078","url":null,"abstract":"","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73841318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of nutritional intervention with vitamin K2 bone turnover markers in healthy indian premenopausal women (25-45 yrs; inclusive): Study design and nutritional bone health biomarkers strategy","authors":"pPankaj Vermap","doi":"10.4172/2155-9600-C6-067","DOIUrl":"https://doi.org/10.4172/2155-9600-C6-067","url":null,"abstract":"","PeriodicalId":16764,"journal":{"name":"Journal of Nutrition and Food Sciences","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81670283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}