Journal of Pediatric Urology最新文献

{"title":"Commentary to \"Early revision patterns and conduit type as predictors of continent catheterizable channel durability in children: A two-center time-to-event analysis\".","authors":"John S Wiener","doi":"10.1016/j.jpurol.2026.106298","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106298","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106298"},"PeriodicalIF":2.2,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary to \"Post-surgical assessment of lower urinary tract dysfunction in ureterocele patients\".","authors":"Hasan Serkan Dogan","doi":"10.1016/j.jpurol.2026.106300","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106300","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106300"},"PeriodicalIF":2.2,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor re: \"Comparative evaluation of sulbutiamine and imipramine in the treatment of primary nocturnal enuresis: A randomized controlled clinical study\".","authors":"Meilin Liu, Zhanli Liu","doi":"10.1016/j.jpurol.2026.106296","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106296","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106296"},"PeriodicalIF":2.2,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149228131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor re: \"Early trajectories and re-evaluation windows after cessation of home-based transcutaneous tibial nerve stimulation in children with overactive bladder: A prospective cohort study\".","authors":"Lexin Chen","doi":"10.1016/j.jpurol.2026.106294","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106294","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106294"},"PeriodicalIF":2.2,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of renal functional reserve in primary vesicoureteric reflux: A cross-sectional study.","authors":"Sukumar Ettiappan, Bobbity Deepthi, Madhusudhanan Ponnusamy, Bikash Kumar Naredi, Sudarsan Krishnasamy, Sriram Krishnamurthy","doi":"10.1016/j.jpurol.2026.106293","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106293","url":null,"abstract":"<p><strong>Background: </strong>The role of renal functional reserve (RFR) in children with vesicoureteric reflux (VUR) is understudied. The objective of this study was to determine RFR [assessed by Diethylenetriaminepentaacetic acid (DTPA) scan] in patients aged 2-18 years with primary VUR.</p><p><strong>Methods: </strong>This cross-sectional study evaluated RFR in 50 children with primary VUR. Baseline and stimulated (after 1 g/kg protein meal) GFR were measured using technetium-99m (Tc-99m) DTPA plasma clearance (Russell's two-sample method). RFR was calculated as the proportional GFR increase, with >10% defined as positive RFR and compared across grades of VUR and scars. RFR was also assessed by timed urinary creatinine clearance.</p><p><strong>Results: </strong>The median age at RFR estimation was 4.3 [IQR:2.9, 8.1] years, while median age-at-diagnosis was 7 [2, 24] months. The median duration of illness was 3.6 [2.3, 6.2] years. Initial presentations included urinary tract infections (UTI) in 31 (62%) children and antenatal hydronephrosis in 18 (36%), with 90% (n = 45) having a history of prior pyelonephritis. Patients were categorized by VUR severity: unilateral low-grade (n = 7; 14%), unilateral high-grade (n = 14; 28%), bilateral high-grade (n = 26; 52%), and bilateral low-grade (n = 3; 6%). The median DTPA RFR was 13.67 [5.84, 28.27]%, with 60% (n = 30) demonstrating a positive RFR. RFR compared among children with low-grade vs high-grade VUR, demonstrated no statistically significant difference (p = 0.28). DTPA-RFR correlated weakly with timed creatinine clearance RFR (r = 0.20), which consistently overestimated RFR. The median-annual-decline rate was higher in group with absent RFR (-4.2 vs improvement of 18.25 mL/min/1.73 m²/year), with a median difference of 22.45 mL/min/1.73 m²/year (bootstrap 95% CI 4.58, 60.74), p = 0.011.</p><p><strong>Conclusions: </strong>In conclusion, preserved RFR was noted in nearly two-thirds of children with VUR, with no significant difference with disease severity. The study demonstrates that RFR can be measured using different methodologies in children with VUR and provides valuable feasibility data.</p>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106293"},"PeriodicalIF":2.2,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Commentary on \"Conservative versus endoscopic initial management of pediatric ureterocele: A systematic review and meta-analysis\".","authors":"Gaayana Raju, Luisa Cunha, Zaneta Frimpong, David Olaewe, McKenna Beck, Oluwafemi Ojo, Andrew Marks, Leon Smith-Harrison, Sebastian Tobia-Gonzalez","doi":"10.1016/j.jpurol.2026.106287","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106287","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106287"},"PeriodicalIF":2.2,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor re: \"Effects of virtual reality and auditory water stimuli on early postoperative voiding after pediatric circumcision: A randomized controlled trial\".","authors":"Mecit Celik","doi":"10.1016/j.jpurol.2026.106290","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106290","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106290"},"PeriodicalIF":2.2,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced-order, computational fluid dynamics-informed pressure-flow simulation of endoscopic injection therapy in pediatric vesicoureteral reflux: An in-silico evaluation of technique-dependent outcomes.","authors":"Jin Kyu Kim, Joshua Roth, Benjamin Whittam, Nikhil Batra, Michael Chua, Rosalia Misseri","doi":"10.1016/j.jpurol.2026.106282","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106282","url":null,"abstract":"<p><strong>Introduction: </strong>Endoscopic bulking therapy is widely used to treat vesicoureteral reflux (VUR), yet technique selection remains largely empiric and outcomes vary by reflux grade and bladder dynamics. We developed a hypothesis-generating, reduced-order, computational fluid dynamics (CFD)-informed pressure-flow simulation intended to explore hydrodynamic mechanisms and injection-strategy tradeoffs.</p><p><strong>Methods: </strong>The model represents the bladder, ureterovesical junction, ureter, and renal pelvis as coupled pressure-flow elements. VUR grade templates modify competence, reverse resistance, dilation, tortuosity, compliance, and peristalsis; bladder-bowel dysfunction (BBD) is represented only as stylized pressure/outlet phenotypes. Injection modifies reverse and antegrade resistance through technique- and volume-dependent transformations. Reflux fraction (RF) was reflux volume divided by reflux plus antegrade volume; the obstruction index (OI) was a modeling safety ceiling, not a clinically validated threshold.</p><p><strong>Results: </strong>In the balanced 75-stratum simulation, the base-case OI ceiling selected Double HIT in 65 strata, Double HIT + STING in 9 strata, and HIT in 1 stratum. These are model outputs reflecting encoded multi-site geometry and volume-splitting assumptions. In the grade-V reference sweep, STING did not reach modeled RF resolution and exceeded the OI ceiling across tested volumes. Bilateral simulations showed small contralateral effects under the current shared-bladder coupling assumptions rather than strong clinical coupling. OI-threshold, mound-sigmoid, and tornado sensitivity analyses were added or specified to evaluate robustness of the model outputs.</p><p><strong>Conclusions: </strong>This CFD-informed model offers a transparent, hypothesis-generating framework for comparing hydrodynamic consequences of endoscopic injection strategies. It does not establish clinical superiority, predict individual outcomes, or define validated treatment thresholds; external validation is required before clinical decision use.</p>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106282"},"PeriodicalIF":2.2,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor re: \"Comparative evaluation of sulbutiamine and imipramine in the treatment of primary nocturnal enuresis: A randomized controlled clinical study\".","authors":"Fen Pan, Jinyan Guo, Chuanli Chen","doi":"10.1016/j.jpurol.2026.106291","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106291","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106291"},"PeriodicalIF":2.2,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary to \"Conservative versus endoscopic initial management of pediatric ureterocele: A systematic review and meta-analysis\".","authors":"Chris Staniorski, Hans G Pohl","doi":"10.1016/j.jpurol.2026.106286","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106286","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106286"},"PeriodicalIF":2.2,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}