Journal of Pharmaceutical Policy and Practice最新文献

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The cost associated with the development of the antimicrobial stewardship program in the adult general medicine setting in Qatar. 卡塔尔成人全科医疗机构制定抗菌药物管理计划的相关成本。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-03-27 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2326382
Dina Abushanab, Wafa Al-Marridi, Moza Al Hail, Palli Valappila Abdul Rouf, Wessam ElKassem, Binny Thomas, Hussam Alsoub, Zanfina Ademi, Yolande Hanssens, Rasha El Enany, Daoud Al-Badriyeh
{"title":"The cost associated with the development of the antimicrobial stewardship program in the adult general medicine setting in Qatar.","authors":"Dina Abushanab, Wafa Al-Marridi, Moza Al Hail, Palli Valappila Abdul Rouf, Wessam ElKassem, Binny Thomas, Hussam Alsoub, Zanfina Ademi, Yolande Hanssens, Rasha El Enany, Daoud Al-Badriyeh","doi":"10.1080/20523211.2024.2326382","DOIUrl":"10.1080/20523211.2024.2326382","url":null,"abstract":"<p><strong>Objective: </strong>To estimate the economic impact of the developed antimicrobial stewardship program (ASP) versus the preliminary ASP use, in the adults' general medicine settings in Qatar.</p><p><strong>Methods: </strong>Patient records were retrospectively reviewed during two periods: preliminary ASP was defined as the 12 months following ASP implementation (i.e. May 2015-April 2016), and developed ASP was defined as the last 12 months of a 5-year ASP implementation in Hamad Medical Corporation (HMC) (i.e. February 2019-January 2020). The economic impact was the overall cost savings in resource use, including operational costs, plus the cost avoidance associated with ASP.</p><p><strong>Results: </strong>A total of 500 patients were included in the study. The operational costs decreased with the developed ASP. Whereas antimicrobial consumption and resource utilisation, and their associated costs, appear to have declined with the developed ASP, with a cost saving of QAR458 (US$125) per 100-patient beds, the avoided cost was negative, by QAR4,807 (US$1,317) per 100-patient beds, adding to a total QAR4,224 (US$1,160) increase in the 100-patient beds cost after ASP development.</p><p><strong>Conclusions: </strong>Despite that the developed ASP attained a total cost saving QAR458 (US$125) per 100-patient beds, the avoided cost was QAR-4,807 (US$-1,317) per 100-patient beds, which exceeded the cost savings achieved.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10977017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140318530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacist management of atrial fibrillation in UK primary care: a cross-sectional study. 英国基层医疗机构药剂师对心房颤动的管理:一项横断面研究。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-03-20 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2321592
Shahd Al-Arkee, Julie Mason, M Sayeed Haque, Abdullah Alshehri, Zahraa Jalal
{"title":"Pharmacist management of atrial fibrillation in UK primary care: a cross-sectional study.","authors":"Shahd Al-Arkee, Julie Mason, M Sayeed Haque, Abdullah Alshehri, Zahraa Jalal","doi":"10.1080/20523211.2024.2321592","DOIUrl":"10.1080/20523211.2024.2321592","url":null,"abstract":"<p><strong>Background: </strong>Atrial Fibrillation (AF) increases the risk of stroke by a factor of five, leading a significant cost burdens on healthcare system. Pharmacists, especially those based in a primary care environment are well placed to support patients in this therapeutic area.</p><p><strong>Objectives: </strong>To assess primary care pharmacists' actual knowledge on the management of AF symptoms and anticoagulation. Furthermore, to investigate the resources used by pharmacists.</p><p><strong>Methods: </strong>A cross-sectional study using survey was conducted, targeting UK-based registered pharmacists employed within primary care settings. Quantitative data were analysed utilising descriptive univariate and bivariate statistics.</p><p><strong>Results: </strong>349 pharmacists completed the adapted 19-questions of the pharmacists' knowledge. Out of a maximum of 19 points, the mean score was 14.34 ± 2.2 (75 ± 11.6%). The questionnaire revealed several significant gaps in pharmacists' knowledge. Most of the surveyed pharmacists (62.8%) reported that they used sources of information to support their consultations. Half reported that they used the National Institute for Health and Care Excellence (NICE) guidance (52.4%) and the British National Formulary (BNF) (50.7%).</p><p><strong>Conclusions: </strong>Primary care pharmacists are knowledgeable about AF and its management; however, some gaps exist which may require addressing. Although pharmacists use a variety of information resources, it is the traditional resources that remain the most frequently used.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10956929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140184739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Odds and associated factors for thrombosis development among Lebanese COVID-19 patients: a case-control retrospective study. 黎巴嫩 COVID-19 患者血栓形成的几率和相关因素:一项病例对照回顾性研究。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-03-14 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2319743
Mahmoud Youness, Sara Mansour, Fouad Sakr, Samer Olabi, Sarah Atwi, Iman Younes Martinez, Sami El Khatib, Souheil Hallit, Pascale Salameh, Diana Malaeb, Hassan Hosseini
{"title":"Odds and associated factors for thrombosis development among Lebanese COVID-19 patients: a case-control retrospective study.","authors":"Mahmoud Youness, Sara Mansour, Fouad Sakr, Samer Olabi, Sarah Atwi, Iman Younes Martinez, Sami El Khatib, Souheil Hallit, Pascale Salameh, Diana Malaeb, Hassan Hosseini","doi":"10.1080/20523211.2024.2319743","DOIUrl":"https://doi.org/10.1080/20523211.2024.2319743","url":null,"abstract":"<p><strong>Background: </strong>Thromboembolism is reported to be up to 27% in COVID-19 patients due to SARS-CoV-2 infection. Dysregulated systemic inflammation and various patient traits play a vital role in thrombosis progression.</p><p><strong>Purpose: </strong>To assess odds and associated factors for thrombosis development among Lebanese COVID-19 patients.</p><p><strong>Methods: </strong>This was a case-control retrospective study conducted in January-May 2021. Patients infected with COVID-19 and developed thrombosis were classified as cases and patients who were thrombosis-free identified as control. A questionnaire assessed socio-demographics, clinical parameters, and WHO COVID-19 disease severity.</p><p><strong>Results: </strong>Among 267 patients, 26 (9.7%) developed thrombosis and the majority of thrombosis 34.6% was myocardial infarction, and the least (3.8%) was for catheter-related thrombosis. Results showed that the risk of thrombosis development is higher in patients with previous thromboembolic event (OR = 9.160) and previous intake of anti-hypertensive medications at home (OR = 3.116). However, females (OR = 0.330; CI: 0.118-0.925), intake of anticoagulants during hospital admission (OR = 0.126; CI: 0.053-0.300) and non-severe COVID-19 were at lower thrombosis risk (OR = 0.273). Patients who developed thromboembolic events had longer hospital stay (OR = 0.077).</p><p><strong>Conclusion: </strong>Patients with COVID-19 and thromboembolism were at higher risk of mortality as compared to patients with COVID-19 but without thromboembolism. The use of anticoagulants significantly reduced the risk for thromboembolism.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10950289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140175160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value of pharmacy services for common illness symptoms covered by universal coverage at drugstore compared to outpatient services at a hospital in Thailand. 泰国全民医保药店针对常见疾病症状提供的药学服务价值与医院门诊服务的比较。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-03-14 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2321585
Parun Rutjanathamrong, Tuangrat Phodha, Thanawat Wongphan, Sirikorn Sujinnaprum, Noppakun Thammatacharee
{"title":"Value of pharmacy services for common illness symptoms covered by universal coverage at drugstore compared to outpatient services at a hospital in Thailand.","authors":"Parun Rutjanathamrong, Tuangrat Phodha, Thanawat Wongphan, Sirikorn Sujinnaprum, Noppakun Thammatacharee","doi":"10.1080/20523211.2024.2321585","DOIUrl":"https://doi.org/10.1080/20523211.2024.2321585","url":null,"abstract":"<p><strong>Background: </strong>Drug stores is an option that people can receive health care services for their common illnesses. This is the first study aims to estimate cost savings for 16 common illness symptoms to the Thailand's health system.</p><p><strong>Method: </strong>This study gathered retrospective secondary data from several studies and surveyed the median cost of medicines. Cost savings of care provided by pharmacists at drug stores in comparison to out-patient department (OPD) services at hospitals were quantified using cost of illness approach.</p><p><strong>Results: </strong>The average number of hospital visits for treatment for 16 common illness symptoms was 2,356 visits per month. The estimation of the cost savings per visit from three perspectives, including government, patient, and societal, at tertiary care hospitals were 12.7-19.4, 12.7-25.6, and 18.9-25.6 USD, and at secondary care hospitals were 6.0-12.7, 6.0-18.9, and 12.2-18.9 USD. Every $1 reimbursed at drug stores will save additional costs in Thailand's health system, ranging from $0.04 to $0.24 and $0.02 to $0.16 at tertiary care hospitals and secondary hospitals, respectively.</p><p><strong>Conclusion: </strong>Pharmacy services for 16 common illness symptoms can clearly save costs.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10950287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140175161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of pharmacist-supported transition of care services in the Middle East and North Africa: a systematic review and meta-analysis. 药剂师支持的护理过渡服务在中东和北非的影响:系统回顾和荟萃分析。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-03-11 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2323099
Eman N Alhmoud, Safa Farooq Fouad Alrawi, Rasha El-Enany, Mohamed Izham Mohamed Ibrahim, Muhammad Abdul Hadi
{"title":"Impact of pharmacist-supported transition of care services in the Middle East and North Africa: a systematic review and meta-analysis.","authors":"Eman N Alhmoud, Safa Farooq Fouad Alrawi, Rasha El-Enany, Mohamed Izham Mohamed Ibrahim, Muhammad Abdul Hadi","doi":"10.1080/20523211.2024.2323099","DOIUrl":"10.1080/20523211.2024.2323099","url":null,"abstract":"<p><strong>Background: </strong>Transition of care (TOC) is associated with an increased risk of medication-related problems. Despite recent advancements in pharmacy practice and research in the Middle East and North Africa (MENA), the characteristics and impact of regional pharmacy-supported TOC interventions remain unclear.This systematic review and meta-analysis aimed to describe pharmacist-supported TOC interventions in the MENA region and evaluate their effectiveness.</p><p><strong>Methods: </strong>PubMed, CINAHL, EMBASE, Web of Science, World Health Organization's International Clinical Trials Registry Platform (ICTRP) were searched from their inception to March 9, 2023, for experimental studies published in English, comparing pharmacist-supported TOC interventions with usual care for adults (age ≥18 years) discharged from the hospital. The risk of bias was evaluated using Cochrane's risk-of-bias tool for randomised trials (ROB2) and the risk of bias in non-randomised studies of interventions (ROBINS-I) tool for randomised and non-randomised studies respectively. Narrative syntheses and meta-analysis methods were employed depending on the outcomes evaluated.</p><p><strong>Results: </strong>Twelve studies (n = 2377 subjects), 10 randomised controlled trials and 2 quasi-experimental studies, were included. Most studies had high or serious risk of bias. The included studies were quite heterogeneous in terms of nature and the delivery of intervention, and assessment of outcome measures. Compared to the usual care group, pharmacist-led TOC interventions contributed to a significant reduction in preventable drug-related (N = 2) and cardiac-related healthcare utilisation (N = 1), a significant reduction in preventable adverse drug events (ADEs) (Odds ratio (OR) 0.34, 95% CI: 0.13-0.94) and an improvement in medication adherence. However, all-cause hospitalisation and medication discrepancies were not significantly reduced.</p><p><strong>Conclusion: </strong>Pharmacy-supported TOC interventions may improve patient outcomes in the MENA region. However, considering the limited quality of evidence and the variability in intervention delivery, future well-designed clinical trials are needed.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10930094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140110488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the role of intern pharmacists in pharmaceutical care in hospitals in Uganda. 评估实习药剂师在乌干达医院药品护理中的作用。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-03-11 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2320282
Agaba Robert, Ndinawe Johnmark, Kabera Makuza Radiana, Kiiza Haulat, Segawa Ivan, Kalidi Rajab, Keren Ebong
{"title":"Evaluating the role of intern pharmacists in pharmaceutical care in hospitals in Uganda.","authors":"Agaba Robert, Ndinawe Johnmark, Kabera Makuza Radiana, Kiiza Haulat, Segawa Ivan, Kalidi Rajab, Keren Ebong","doi":"10.1080/20523211.2024.2320282","DOIUrl":"10.1080/20523211.2024.2320282","url":null,"abstract":"<p><strong>Background: </strong>In Uganda, there is limited adoption of pharmaceutical care in hospitals due to pharmacist shortages and limited collaboration among healthcare professionals. Intern pharmacists are deployed annually to assist in patient care to address pharmacist shortages.</p><p><strong>Objectives: </strong>Evaluate intern pharmacist's extent of involvement in pharmaceutical care activities, assess facilitators and barriers, and explore healthcare professionals' perceptions, attitudes, and opinions on implementation of pharmaceutical care.</p><p><strong>Methods: </strong>A mixed-method concurrent study was carried out for four months. We conducted an online survey among 107 intern pharmacists from 26 hospitals, including National Referral, Regional Referral, Private Not-For-Profit, and General hospitals; predictors of extent of involvement were identified using linear regression models, using STATA 14. 24 key informants (nurses, prescribers, pharmacists) from five hospitals were interviewed; themes were developed using a deductive thematic analysis approach.</p><p><strong>Results: </strong>Intern pharmacists had a median (Interquartile range[IQR]) age of 25 years (25-27) and 74.7% were male. About half (54.1%) of key informants were female and had a median (IQR) of 10 years (4.0-15.5) of professional experience. Interns focused on patient counseling, lacked documentation, and showed positive attitudes, and knowledge. Key informants supported implementation, but prescribers expressed dissatisfaction with interns' performance.</p><p><strong>Conclusion: </strong>Enhancing pharmacy internship and training through developing policies and guidelines on pharmaceutical care practice, improving working conditions, and mentorship can address gaps impeding pharmaceutical care implementation by intern pharmacists.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10930095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140110487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Professional stigma towards clients with methamphetamine use disorder - a qualitative study. 对甲基苯丙胺使用障碍患者的职业羞辱--一项定性研究。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-03-06 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2306869
Ali Makki, Carolyn Day, Betty B Chaar
{"title":"Professional stigma towards clients with methamphetamine use disorder - a qualitative study.","authors":"Ali Makki, Carolyn Day, Betty B Chaar","doi":"10.1080/20523211.2024.2306869","DOIUrl":"10.1080/20523211.2024.2306869","url":null,"abstract":"<p><strong>Background: </strong>Methamphetamine use disorder (MUD) is associated with poor health outcomes. Pharmacists play a role in delivery of substance use treatment, with several studies having examined their attitudes to people with opioid use disorder, but little is known about their attitude towards people with MUD. This study aimed to explore pharmacists' perspectives on the provision of services to clients with MUD.</p><p><strong>Methods: </strong>A convenience sampling strategy was used to recruit community pharmacists across Sydney, Australia. Semi structured interviews examined views and ideas of pharmacists surrounding the treatment and management of MUD, followed by coding of transcribed interview data by all members of the research team.</p><p><strong>Results: </strong>Nineteen pharmacists completed the interviews. The main theme identified was stigma held by healthcare professionals. The almost unanimous perception amongst pharmacists was fear and apprehension towards people with MUD, including underlying assumptions of criminality, misinformation regarding people with MUD, and lack of education and knowledge surrounding MUD.</p><p><strong>Conclusion: </strong>A substantial amount of stigma towards people with MUD was found in this study. Negative attitudes by healthcare professionals can perpetuate healthcare disparities and impede the accessibility of future treatment programs for people with MUD. Appropriate educational interventions on MUD for pharmacists are needed.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140059668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Promoting local production and active pharmaceutical ingredient (API) industry in low and middle income countries (LMICs): impact on medicines access and policy. 促进中低收入国家(LMICs)的本地生产和活性药物成分(API)产业:对药品获取和政策的影响。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-03-04 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2323683
Muhammad Akhtar Abbas Khan, Asim Rauf
{"title":"Promoting local production and active pharmaceutical ingredient (API) industry in low and middle income countries (LMICs): impact on medicines access and policy.","authors":"Muhammad Akhtar Abbas Khan, Asim Rauf","doi":"10.1080/20523211.2024.2323683","DOIUrl":"10.1080/20523211.2024.2323683","url":null,"abstract":"<p><p>The success of universal coverage depends on ensuring that patients have access to medicine. Encouraging local production of medicines in developing countries can provide better access to medicines. In addition to determining the quality of pharmaceutical goods, Active Pharmaceutical Ingredients (APIs) also determine their cost. According to market forecasts, the active pharmaceutical ingredients market is expected to increase from USD 193.15 billion in 2023 to USD 285.29 billion by 2028. Pakistan largely depends on India and China for its Active Pharmaceutical Ingredient requirements. It was feared that a shortage of medicines would result from Pakistan's government suspending all trade with India on August 9, 2019. To improve health security in Pakistan, the Government of Pakistan has introduced an API promotion Policy in 2022. Financial and non-financial incentives have helped many countries develop their API industries like China, India, and Bangladesh. The current domestic API market of Pakistan is around 150 million $. After the introduction of the policy, the existing units are increasing their capacity while eight new API units are in the process of establishment. Through local production of APIs and intermediates, Pakistan can improve its health security by learning from the experiences of neighbouring countries, especially China.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10913693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140039613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medicare Part B and Part D drug eligibility for center for Medicare and Medicaid Services price negotiation under the Inflation Reduction Act: estimates using 2016-2019 data. 根据《通货膨胀削减法》,医疗保险 B 部分和 D 部分药物有资格参加医疗保险和医疗补助服务中心的价格谈判:使用 2016-2019 年数据进行的估算。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-02-29 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2312374
Omar Qureshi, Reshma Ramachandran, Joseph S Ross
{"title":"Medicare Part B and Part D drug eligibility for center for Medicare and Medicaid Services price negotiation under the Inflation Reduction Act: estimates using 2016-2019 data.","authors":"Omar Qureshi, Reshma Ramachandran, Joseph S Ross","doi":"10.1080/20523211.2024.2312374","DOIUrl":"10.1080/20523211.2024.2312374","url":null,"abstract":"<p><strong>Background: </strong>To reduce Medicare prescription drug expenditures, the 2022 Inflation Reduction Act (IRA) allows the Centers for Medicare & Medicaid Services (CMS) to directly negotiate with drug manufacturers on Medicare prices of high-expenditure drugs (≥$200m annual spending) which meet certain eligibility criteria. However, it is unclear what proportion of high-expenditure drugs covered by Medicare, and attributable annual drug spending, would typically be eligible for CMS negotiations in a given year.</p><p><strong>Methods: </strong>We used historical Medicare drug spending data to determine how many high-expenditure drugs, and attributable drug spending, would have been eligible for CMS negotiations had the IRA been in effect from 2016-2019, while also determining which of the IRA's eligibility criteria is most restrictive.</p><p><strong>Results: </strong>From 2016-2019, approximately one third (33.3% for Part B, 32.4% for Part D) of high-expenditure Medicare drugs would have been eligible for negotiation, with ineligible drugs accounting for 75.2% and 63.8% of spending on high-expenditure drugs in Medicare Part B and D, respectively. Most ineligible high-expenditure drugs were ineligible because they launched too recently. From 2016-2019, between 59 and 74 high-expenditure drugs were eligible per year, indicating that in some years there may not be enough eligible drugs for CMS to negotiate on the maximum number of drugs allowable by law.</p><p><strong>Conclusions: </strong>The IRA's current eligibility criteria may restrict CMS from being able to negotiate drug prices on approximately two-thirds of the high-expenditure drugs covered by Medicare and may not allow CMS to negotiate on the maximum number of drugs allowable by law. Congress could consider relaxing eligibility requirements for price negotiation, such as those pertaining to launch date recency, to ensure there are a sufficient number of high-expenditure drugs eligible for negotiation or make certain ineligible drugs contributing to significant annual Medicare spending eligible for negotiation on a case-by-case basis.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating drug use patterns among paediatric outpatients in Burundi. 评估布隆迪儿科门诊患者的用药模式。
IF 4.2
Journal of Pharmaceutical Policy and Practice Pub Date : 2024-02-29 eCollection Date: 2024-01-01 DOI: 10.1080/20523211.2024.2312369
Audace Manirakiza, David Gitonga Nyamu, Shital Mahindra Maru, Thomas Bizimana, Manassé Nimpagaritse
{"title":"Evaluating drug use patterns among paediatric outpatients in Burundi.","authors":"Audace Manirakiza, David Gitonga Nyamu, Shital Mahindra Maru, Thomas Bizimana, Manassé Nimpagaritse","doi":"10.1080/20523211.2024.2312369","DOIUrl":"10.1080/20523211.2024.2312369","url":null,"abstract":"<p><strong>Background: </strong>Rational prescribing is key to optimising therapeutic outcomes and avoiding risks associated with irrational use of medicines. Using WHO drug use indicators, this study evaluated drug use patterns among paediatric outpatient encounters at Primary Healthcare Centers (PHCs) in Bujumbura Mairie, Republic of Burundi.</p><p><strong>Methods: </strong>Descriptive cross-sectional research assessed paediatric medicine use in 20 PHCs. From 8 February to 7 April 2023, 800 randomly selected paediatric encounters' 2022-year data were retrospectively collected. Data for specific facility indicators were prospectively collected. SPSS 23 was used to analyse data.</p><p><strong>Results: </strong>800 outpatient child encounters were analysed, 48.4% female and 51.6% male. The mean number of medicines per encounter was 2.4(±0.99). The injection rate was 9.9%. Overall, 78.8% of generics and 85.2% of essential medicines were prescribed. Results show drug prescribing differences between private and government PHCs (<i>p </i>< 0.001). All PHCs studied had no standard treatment guidelines (STGs), while 50% had an essential medicine list (EML) and 85% of key medicines were available.</p><p><strong>Conclusion: </strong>Poor prescribing practices were found indicating the need for interventions to promote good drug use practices. A large study at a national scale is required to provide a more comprehensive understanding of the overall drug use practices.</p>","PeriodicalId":16740,"journal":{"name":"Journal of Pharmaceutical Policy and Practice","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140039685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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