Journal of periodontology最新文献

{"title":"Effect of an intensive antiplaque regimen on microbiome outcomes after nonsurgical periodontal therapy","authors":"Lu Li, Yoshiko Hayashi-Okada, Karen L. Falkner, Yasumitsu Shimizu, Joseph J. Zambon, Keith L. Kirkwood, Robert E. Schifferle, Robert J. Genco, Patricia I. Diaz","doi":"10.1002/JPER.24-0141","DOIUrl":"10.1002/JPER.24-0141","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>It has been well documented that periodontal treatment decreases the levels of certain disease-associated species in subgingival plaque. Few studies, however, investigate to which extent periodontal therapy restores a health-like subgingival community. Here, we conducted a secondary analysis to evaluate microbiome outcomes of nonsurgical periodontal therapy alone or followed by an intensive antiplaque regimen, analyzing microbiome trajectories at the community level with respect to health.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Eighty-six subjects with periodontitis stages II/III were evaluated at baseline and 6 months after receiving scaling and root planing alone (SRP, <i>n</i> = 41) or followed by an antiplaque regimen consisting of use of 0.12% chlorhexidine for 3 months and interdental cleaners for 6 months (SRP + P + S, <i>n</i> = 45). Thirty periodontally healthy subjects served as reference. The subgingival microbiome was characterized by 16S rRNA gene sequencing, and longitudinal within-subject changes were quantified with respect to a healthy plane (HPL) modeled from the reference group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Evaluation of individual microbiome trajectories showed that only the SRP + P + S group had a statistically significant reduction in distance to the HPL. However, responses were variable in both groups, with only a fraction of individuals changing in the direction of health. Random forest analysis revealed baseline microbiome composition as a greater predictor of microbiome response than type of treatment rendered.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>An adjunct antiplaque regimen resulted in a greater approximation of the microbiome to the healthy state. However, responses varied greatly among subjects highlighting the need for robust and personalized approaches to restore eubiosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Plain Language Summary</h3>\u0000 \u0000 <p>This study looked at how different treatments for gum disease change the bacteria in the gums of people with moderate to severe gum problems. Eighty-six people received standard gum treatments, and some also used a mouthwash and special tools to clean between their teeth at home. After 6 months, more people in the group that added the extra cleaning steps had healthier bacteria in their gums than people who received the standard treatment. However, not everyone responded the same way. The study found that the types of bacteria someone had at the start were better at predicting how well the treatment would work, more","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":"96 3","pages":"241-254"},"PeriodicalIF":4.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency, cost, and time to re-treatment after active periodontal therapy.","authors":"Shahad Alhazmi, Sawsan Abu-Reyal, Yi-Chen Chiang, Muhammad H A Saleh, Hom-Lay Wang","doi":"10.1002/JPER.24-0474","DOIUrl":"https://doi.org/10.1002/JPER.24-0474","url":null,"abstract":"<p><strong>Background: </strong>Supportive periodontal therapy (SPT) reduces the probability of infection reoccurrence further disease progression. Despite that, several patient/tooth related variables have been linked to tooth loss during SPT. This longitudinal study examines the correlation between periodontal staging, grading, initial therapy, and frequency, cost, and time-to-re-treatment following active periodontal therapy (APT).</p><p><strong>Methods: </strong>Patients who received scaling and root planing (SRP) or surgery (SUR) were included. Demographics, annual SPT visits, and medical history were collected. Radiographic bone loss (RBL), probing depths (PD), and clinical attachment loss were collected at six sites/tooth. A simple binary logistic regression model assessed the probability of re-treatment. Multiple models were constructed while adjusting for confounding factors: sex, age, number of SPT visits, and baseline data.</p><p><strong>Results: </strong>Three hundred patients underwent SRP, and 142 underwent SUR as their APT. 191 patients (63.7%) required a second intervention over 24 ± 8.2-year follow-up. The second intervention type was correlated with the first (p = 0.035). The likelihood of a second intervention was higher in SUR patients (p < 0.001). Significant differences in time to first intervention based on stage (p = 0.019) and compliance (p < 0.001). Similar patterns were observed for time-to-recurrence based on stage (p = 0.03) and compliance (p = 0.017) but not grade (p = 0.144). Mean teeth \"free of intervention time\" was 16.3 years before the first additional therapy. However, SSD was found between stages (p = 0.028) and grades (p = 0.043) for SUR interventions, but not for SRP.</p><p><strong>Conclusion: </strong>In this long-term study, higher stage patients and those who had surgical treatments received more frequent retreatments. The first intervention affected the likelihood and type of the second intervention. 12.4% of patients were responsible for 64% of the entire retreatment spending.</p><p><strong>Plain language summary: </strong>Patients with more severe periodontitis who initially underwent surgery needed more frequent therapy. Patients who had surgery as their intervention during active periodontal therapy were more prone to have surgery as their additional therapy during follow-up.</p>","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presence of nonimpacted third molars affect the response of neighboring teeth to nonsurgical periodontal therapy.","authors":"Rui Gao, Li-Juan Sun, Xi-Yu Zhang, Hong-Lei Qu, Yi Tian, Xiao-Tao He, Xuan Li, Bei-Min Tian, Fa-Ming Chen, Rui-Xin Wu","doi":"10.1002/JPER.24-0674","DOIUrl":"https://doi.org/10.1002/JPER.24-0674","url":null,"abstract":"<p><strong>Background: </strong>This study focused on whether the effectiveness of nonsurgical periodontal therapy (NSPT) on second molars (M2s) varies with the status of adjacent nonimpacted third molars (N-M3s).</p><p><strong>Methods: </strong>In this retrospective cohort study, 776 regions from 268 patients were evaluated. Based on the adjacent N-M3 status, quadrants with M2s were categorized into three groups: N-M3 group (present N-M3), A-M3 group (absent M3), and R-M3 group (removed N-M3). The probing depth reduction (ΔPD) and the percentage of reversed deep pockets (PD5+ [probing depth ≥5 mm] turned to PD5-) after NSPT were analyzed among the three groups. The Wilcoxon nonparametric test was employed to compare the N-M3 group with the A-M3 group, with a mixed-effect model utilized to adjust for confounding factors. Further, the R-M3 group and the matched N-M3 group were compared using the Wilcoxon nonparametric test.</p><p><strong>Results: </strong>After isolating confounding factors (M2 baseline gingival recession, tooth mobility, sex, and follow-up interval), the ΔPD of M2s was significantly lower in the N-M3 group (0.93 ± 1.25 mm) compared with the A-M3 group (1.09 ± 1.30 mm, p < 0.001). Moreover, the percentage of reversed deep pockets in the N-M3 group (35.56%) was lower than in the A-M3 group (42.98%, p<0.001). Similarly, compared with the N-M3 group, M2s in the R-M3 group manifested better outcomes in terms of periodontal indices.</p><p><strong>Conclusion: </strong>Retained N-M3s may hamper the outcome of NSPT on adjacent M2s. Additionally, the removal of N-M3 is associated with an enhanced response of M2s to NSPT.</p><p><strong>Plain language summary: </strong>The second molar is crucial for chewing, but it is often lost due to periodontitis. Periodontal treatment for the second molar is not always effective, and many factors contribute to this. One factor that has gained attention is the impact of a nonimpacted third molar on the periodontal health of the adjacent second molar. In this study, we examined how the presence of a nonimpacted third molar affects the outcome of nonsurgical periodontal therapy for the second molar. We analyzed 776 second molars from 268 patients. The results showed that when the nonimpacted third molar was absent or removed during periodontal therapy, the second molar's condition improved more than when the nonimpacted third molar was present. The data indicated that even with nonsurgical periodontal treatment, the periodontitis of the second molar could not be effectively controlled if an adjacent nonimpacted third molar was present. Therefore, the negative impact of the nonimpacted third molar should be considered to prevent the loss of the second molar.</p>","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual dimorphism in periodontal inflammation: A cross‐sectional study","authors":"Roberto Farina, Anna Simonelli, Cristiano Tomasi, Effie Ioannidou, Leonardo Trombelli","doi":"10.1002/jper.24-0466","DOIUrl":"https://doi.org/10.1002/jper.24-0466","url":null,"abstract":"BackgroundThe purpose of the present study was to evaluate the role of sexual dimorphism (SD) in the clinical manifestation of plaque‐induced periodontal inflammation by analyzing the association between patient‐related factors and the full‐mouth prevalence of bleeding on probing (BOP%) within 2 cohorts of male and female individuals.MethodsData on BOP (dichotomously recorded as present/absent after the assessment of probing depth [PD]) were retrospectively obtained from the files of adult patients undergoing a first periodontal visit at a University center. Two multiple regression models (1 for males, 1 for females) were built with BOP% as the dependent variable and patient‐related factors (i.e., age; smoking status; daily cigarette consumption; history of diabetes diagnosis; number of teeth present; proportion of sites with PD ≥ 5 mm around teeth) as independent variables.ResultsIn males (&lt;jats:italic&gt;n&lt;/jats:italic&gt; = 212), BOP% was 5.9% lower in smokers compared to non‐smokers (&lt;jats:italic&gt;p &lt;/jats:italic&gt;= 0.021). In females (&lt;jats:italic&gt;n&lt;/jats:italic&gt; = 389), BOP% increased by 1.6% for each 10‐year increase in age (&lt;jats:italic&gt;p &lt;/jats:italic&gt;= 0.046). The proportion of sites with PD ≥ 5 mm showed a strongly significant, positive association with BOP% irrespective of biological sex (&lt;jats:italic&gt;p &lt;/jats:italic&gt;&lt; 0.001).ConclusionSD manifested as a sex‐dependent diversity in the association between patient‐related factors and periodontal inflammation expressed as BOP%. While smoking determined a lower BOP% only in males, aging was associated with increased BOP% only in females.Plain Language SummaryGingival bleeding upon mechanical stimulation of the bottom of the gingival sulcus/pocket with a periodontal probe (bleeding on probing [BOP]) is suggestive of the presence of an inflammatory infiltrate induced by dental plaque within the gingival tissue. The prevalence of BOP within the dentition (BOP%) has a diagnostic relevance, being one of the main parameters to discriminate between periodontal health and disease. Also, BOP% informs the probability for a patient to either develop destructive form of periodontal disease (i.e., periodontitis) or manifest periodontitis progression. Based on the documented influence of biological sex on the incidence, traits, and/or progression rate of several diseases, which goes under the name of sexual dimorphism (SD), the effect of SD was investigated in relation to the factors that were previously associated with BOP% in a cohort of patients with heterogeneous periodontal conditions undergoing their first periodontal visit. Interestingly, SD manifested as a sex‐dependent diversity in the association between patient‐related factors and periodontal inflammation expressed by BOP%. While smoking determined a lower BOP% only in males, aging was associated with increased BOP% only in females. The present findings may find potential applications in personalized periodontal medicine and inspire future studie","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":"28 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143125242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silk‐fibroin chitosan film for palatal wounds: Material development, in vitro study, and pilot clinical trial","authors":"Ingrid Fernandes Mathias‐Santamaria, Manuela Maria Viana Miguel, Ana Carolina Ferreira Bonafé, Camila Nunes Lemos, Lucas de Paula Ramos, Luciane Dias de Oliveira, Renato Correia Vianna Casarin, Renata Fonseca Vianna Lopez, Mauro Pedrine Santamaria","doi":"10.1002/jper.24-0441","DOIUrl":"https://doi.org/10.1002/jper.24-0441","url":null,"abstract":"BackgroundIn the present study, we aim to assess a novel silk‐fibroin (SF) chitosan (CH) film to treat oral mucosa wounds.MethodsThe SF/CH films, sterilized with 130 Gy in a gamma cell, were subjected to tests for thickness, water vapor permeability, tensile strength, elongation, and swelling as well as scanning electron microscopy. Additionally, in vitro cytotoxicity and genotoxicity were evaluated using human epidermal keratinocytes, human foreskin fibroblasts, and human gingival fibroblasts. A pilot clinical trial was conducted with 10 patients who underwent a free gingival graft procedure for socket preservation. The palatal wound healing was evaluated through clinical, patient‐centered, immunological, and histological assessments.ResultsThe SF/CH film exhibited a thickness of 187.5 ± 8.0 µm and water vapor permeability of 15.87 ± 7.52 g mm m&lt;jats:sup&gt;2&lt;/jats:sup&gt; day&lt;jats:sup&gt;−1&lt;/jats:sup&gt; kPa&lt;jats:sup&gt;−1&lt;/jats:sup&gt;, and microscopy revealed a uniformly rough surface. A flexible scaffold was observed (Young's modulus = 1.74 ± 0.90 MPa) with 1% of water absorption within 2 h. The in vitro analysis showed increased cell viability and low genotoxicity for epithelial and fibroblast cells. For the clinical assessments, wound closure was 28.06 ± 4.3mm&lt;jats:sup&gt;2&lt;/jats:sup&gt; and 0.95 ± 1.9mm&lt;jats:sup&gt;2&lt;/jats:sup&gt; after 7 and 14 days, respectively. The immunological assay exhibited a decrease in tissue inhibitor of metalloproteinase‐1 (TIMP‐1) (&lt;jats:italic&gt;p&lt;/jats:italic&gt; = 0.02) and an increase in macrophage inflammatory protein‐1 alpha (MIP‐1α) (&lt;jats:italic&gt;p&lt;/jats:italic&gt; = 0.008) from Day 3 to Day 7. Histology showed the absence of residual biomaterial after 12 months. Complete epithelialization was reached on Day 21, and no tissue thickness loss was observed after 90 days. Patients reported low discomfort and minimal analgesic intake.ConclusionWithin the present study's limits, SF/CH film may be useful to help in the healing of wounds on the palatal mucosa. Further clinical investigations are required.Plain language summaryThis study aimed to evaluate a novel silk fibroin and chitosan film for treating palatal mucosa wounds. The films were sterilized, tested for physical properties, such as thickness, tensile strength, elongation, water vapor permeability, and swelling, and subjected to scanning electron microscopy. In vitro tests using human oral and skin cells assessed the film's toxicity. Ten patients undergoing graft‐harvesting procedures received the film, and their healing was monitored clinically, immunologically, and histologically. The film demonstrated appropriate physical properties, and laboratory results indicated high cell viability and low toxicity. Clinically, the wounds demonstrated considerable closure by Day 7 and almost full closure by Day 14. Immunological assessments indicated elevation in some healing markers, and histology revealed no residual biomaterial at 12 months post treatment. Complete epithelialization occurred b","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":"12 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143125061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Memoriam: William Becker, DDS","authors":"","doi":"10.1002/JPER.24-0648","DOIUrl":"10.1002/JPER.24-0648","url":null,"abstract":"","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":"96 2","pages":"117-118"},"PeriodicalIF":4.2,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143125229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global burden and trends of severe periodontitis among women of childbearing age, 1990-2021.","authors":"Xingzhu Dai, Yifan Tao, Jing Zhou, Yu Zhou, Shuyi Liang, Xiao Ma","doi":"10.1002/JPER.24-0615","DOIUrl":"https://doi.org/10.1002/JPER.24-0615","url":null,"abstract":"<p><strong>Background: </strong>The global burden and trend of severe periodontitis, as well as its association with sociodemographic development, among women of childbearing age (WCBA) have been unclear so far. This study aims to assess the epidemiological pattern of severe periodontitis in WCBA from 1990 to 2021 and provide projections through 2040.</p><p><strong>Methods: </strong>Data on the incidence, prevalence, and disability-adjusted life years (DALYs) of severe periodontitis among WCBA from 1990 to 2021 were retrieved from the Global Burden of Disease (GBD) study 2021. The Bayesian age-period-cohort model was run to project the age-standardized incidence rate (ASIR) through 2040.</p><p><strong>Results: </strong>In 2021, an estimated 26,315,786 incident cases, 257,234,399 prevalent cases, and 1,680,425 DALYs were reported globally. From 1990 to 2021, a consistent annual increase in the age-standardized rate of severe periodontitis was observed, and the ASIR is projected to continue to rise until 2040. Additionally, the burden of severe periodontitis demonstrated a downward trend with increasing sociodemographic development. In 2021, age-specific rates of severe periodontitis increased with age, with the most significant changes occurring in younger age groups.</p><p><strong>Conclusion: </strong>The rising global burden of severe periodontitis, along with regional and age variations, highlights the urgent need for innovative prevention and healthcare strategies to reduce this burden among WCBA globally.</p><p><strong>Plain language summary: </strong>Women of childbearing age (WCBA) represent nearly a quarter of the global population, yet there is a significant gap in consistent global and regional surveillance data on severe periodontitis in this group. Our study revealed that severe periodontitis among WCBA poses a substantial public health challenge worldwide. From 1990 to 2021, the age-standardized rate of severe periodontitis increased globally, with the most significant rise observed in regions with middle socioeconomic development. This condition disproportionately affects women in their prime years, with the fastest growth seen among younger WCBA. It is essential that healthcare providers recognize the gender disparities and societal factors related to socioeconomic development that contribute to the risk of severe periodontitis in this population. To address this issue effectively, it is crucial to develop region- and age-specific prevention strategies, as well as targeted healthcare interventions.</p>","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hotspots and global trends in research of host immune response in periodontitis: A bibliometric analysis.","authors":"Aldrin André Huamán-Mendoza, Fabiola Lucía Pantigozo-Morán, José Carlos da Silva, Casimira Valeria Chuquimez-Ventura, Marinella Holzhausen","doi":"10.1002/JPER.24-0473","DOIUrl":"https://doi.org/10.1002/JPER.24-0473","url":null,"abstract":"<p><strong>Background: </strong>The host immune response plays a major role in the pathogenesis of periodontitis. A bibliometric study can be crucial to understanding the different processes involved in this area; however, to our knowledge, it has not been published until now. Therefore, a bibliometric analysis was conducted to assess research hotspots and global trends in scientific articles about the immune response in periodontitis published between 1952 and 2023.</p><p><strong>Methods: </strong>The search strategy was defined using keywords and Boolean operators. The Web of Science Core Collection database was used. In addition, the bibliometric analysis was performed using four tools: Python 3.12, VOSviewer 1.6.19, R-Bibliometrix, and CiteSpace.</p><p><strong>Results: </strong>A total of 7696 articles were included, comprising 6691 regular articles and 1005 review articles. Data analysis revealed an increasing trend in the number of publications over the years in this field, with the most cited article written by Preshaw et al. (2012). Leading countries in article production include the United States, China, Japan, and Brazil. Regarding institutions, the University of Helsinki had the highest number of publications (N = 339), with one of its researchers being the author with the most publications (Dr. Sorsa, N = 143, H-index = 52). Concerning journals, the Journal of Periodontology was the most influential journal. Finally, recent trending topics in research were related to the influence of inflammation on dysbiosis, immune biomarkers, immunomodulation, and the impact of aging on immunocompetence.</p><p><strong>Conclusion: </strong>This bibliometric study demonstrated a growing interest and the emergence of new trends in research on host immune response in periodontitis.</p>","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of initial bone morphology on alveolar bone remodeling following molar extraction: A retrospective study.","authors":"Ren-Jie Lin, Anna Dai, Jia-Ping Huang, Meng Wang, Wen-Tao He, Pei-Hui Ding","doi":"10.1002/JPER.24-0342","DOIUrl":"https://doi.org/10.1002/JPER.24-0342","url":null,"abstract":"<p><strong>Background: </strong>The clinical evidence about alveolar ridge changes following molar extraction and how the alveolar bone morphology influences the ridge dimensional changes remains limited.</p><p><strong>Methods: </strong>A total of 192 patients with 199 molar extractions were included in this retrospective study. Cone-beam computed tomography (CBCT) images of patients were obtained 0-3 months pre extraction and 6-12 months post extraction. Outcome variables included the change rate in ridge height and width. The effect of morphology on the outcomes was explored by single-factor analysis, correlation analysis, and a multiple linear regression model.</p><p><strong>Results: </strong>Significant resorption of alveolar bone occurred vertically and horizontally after molar extraction. Jaw, furcation involvement, number of roots, number of bone wall defects, extraction reasons, overall relative bone loss (RBL), bone height of the furcation region, thickness of the lingual/palatal wall, and height difference between buccal and lingual/palatal walls (|HB-HL|) were significantly correlated with the change in the height of the central alveolar bone (HC). The number of bone wall defects, overall RBL, and |HB-HL| were significantly correlated with horizontal width change. HC resorption was higher in sockets with |HB-HL| > 2.5 mm and overall RBL > 50%.</p><p><strong>Conclusions: </strong>The alveolar bone presented significant resorption after extraction. Anatomical characteristics affected the dimensions of the alveolar bone after molar extraction. When the initial overall RBL was severe or |HB-HL| was larger, the loss of alveolar bone dimensions was even more.</p><p><strong>Plain language summary: </strong>In recent years, it has been demonstrated that the local anatomical morphology of extraction sites may influence the process of alveolar bone remodeling. However, most studies have focused on the anterior teeth, with fewer investigations addressing molar extraction sites. Therefore, we aimed to describe ridge changes following molar extraction and investigate how alveolar bone morphology influences ridge dimensional changes. In this retrospective study, we included a total of 199 alveolar sockets from 192 patients with molar extractions and obtained the corresponding cone-beam computed tomography (CBCT) images 0-3 months pre extraction and 6-12 months post extraction. The results showed significant resorption of the alveolar bone following molar extraction. We found that anatomical characteristics significantly affect the dimensions of the alveolar bone after molar extraction. Specifically, the loss of alveolar bone dimensions was greater when the initial overall relative bone loss (RBL) was severe or when the difference between buccal and lingual/palatal walls was greater.</p>","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in health care expenditure due to the comorbidity status of periodontal disease and diabetes mellitus","authors":"Anna Kinugawa, Kenji Takeuchi, Yudai Tamada, Taro Kusama, Misuzu Sato, Megumi Maeda, Fumiko Murata, Ken Osaka, Haruhisa Fukuda","doi":"10.1002/jper.24-0496","DOIUrl":"https://doi.org/10.1002/jper.24-0496","url":null,"abstract":"BackgroundTo investigate the differences in health care expenditure (HCE) due to the comorbidity status of periodontal disease (PD) and diabetes mellitus (DM).MethodsThis cohort study used health care claims and oral health screening data to identify participants with PD or DM and followed them for 1 year to assess their HCE. PD and DM were determined based on PD screening and medical claims data, respectively. The study participants were divided into four groups: participants without PD and DM (PD−/DM−), participants with PD and without DM (PD+/DM−), participants without PD and with DM (PD−/DM+), and participants with PD and DM (PD+/DM+). Covariates included age, sex, smoking status, and Charlson Comorbidity Index (CCI) score. A generalized linear model (GLM) with a gamma distribution and log link function was used to examine the association between comorbidity and annual HCE, and a two‐part model was used to assess the differences in annual HCE.ResultsIn total, 790 participants (mean age: 63.1, 30.3% male) were included. Compared with the PD−/DM− group, the relative cost ratio (RCR) for the PD+/DM+, PD−/DM+, PD+/DM− groups were 1.31 (95% confidence interval [CI]: 1.06–1.62), 1.27 (95% CI: 0.99–1.64), 1.01 (95% CI: 0.89–1.14) times higher, respectively. The adjusted mean annual HCE for the PD+/DM+, PD−/DM+, PD+/DM− groups were ¥59,328 (95% CI: 14,171–104,484), ¥50,228 (95% CI: −15,801–116,256), ¥‐2,162 (95% CI: −24,598–20,274) higher than the PD−/DM− group, respectively.ConclusionThis study provides a significant contribution of PD to the increase in HCE, particularly in individuals with DM.Plain Language SummaryThe association between periodontal disease (PD) and diabetes mellitus (DM) has commonly been described in previous literature, but the health expenditure incurred when PD and DM coexist is not clear. This study investigates the differences in health care expenditure (HCE) due to the comorbidity status of PD and DM. HCE is calculated from medical, dental, and pharmacy‐dispensing expenditures from the claims data. PD was defined by periodontal pocket scores, and DM was determined based on medical records. Study participants were divided into four groups based on whether they had PD, DM, both, or neither. The results showed that people with both PD and DM had higher HCE compared with those without PD and DM. These findings may suggest the importance of cooperation between medical and dental professionals in the treatment of DM in terms of HCE.","PeriodicalId":16716,"journal":{"name":"Journal of periodontology","volume":"20 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142988542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}