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Study of Optimal Administration Method of Tazobactam / Piperacillin Using Monte Carllo Simulation 蒙特卡罗模拟研究他唑巴坦/哌拉西林最优给药方法
Yamaguchi Medical Journal Pub Date : 2017-05-01 DOI: 10.2342/ymj.66.105
Yoshitaka Kawaguchi
{"title":"Study of Optimal Administration Method of Tazobactam / Piperacillin Using Monte Carllo Simulation","authors":"Yoshitaka Kawaguchi","doi":"10.2342/ymj.66.105","DOIUrl":"https://doi.org/10.2342/ymj.66.105","url":null,"abstract":"Monte Carlo simulation method was used to examine optimal administration method of Tazobactam / Piperacillin （ TAZ/PIPC ） against Pseudomonas aeruginosa （ P. aeruginosa ）． The dose to obtain≥50% Time above MIC （ %T>MIC ） by renal functions and target attainment rates （ TA% ） ≥80% ware calculated for 12 administration methods. Pharmacokinetic parameters were established according to population pharmacokinetic analyses in Japanese patients with pneumonia, whereas MIC was determined using the MIC 90 from the antibiogram of P. aeruginosa isolated at the Yamaguchi Hospital in a 5‑year period starting in 2011. Our recommended criteria for optimum administration was TA with 50%T ＞ MIC, and prioritizing facility for the patient （ low‑dose, lower frequencies and shorter infusion time ）． The suggest a recommendation of for patients with creatinine CLcr for patients with CLcr mL/min, CLcr infusion in CLcr≥80mL/min there was variation in MIC 90 levels between periods ： some cases have much higher MIC 90 value, in which case the optimal dosage could not be recommended within the indicated","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116955220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-grade Differentiated Adenocarcinoma of the Gastric Foveolar Type Arising in the Helicobacter pylori -negative Stomach 幽门螺杆菌阴性胃中发生的胃小凹型低级别分化腺癌
Yamaguchi Medical Journal Pub Date : 2017-02-01 DOI: 10.2342/YMJ.66.41
S. Sasaki, J. Nishikawa, M. Nagao, R. Ogawa, Atsushi Goto, Shinichi Hashimoto, T. Okamoto, Chieko Suzuki, Y. Hoshii, I. Sakaida
{"title":"Low-grade Differentiated Adenocarcinoma of the Gastric Foveolar Type Arising in the Helicobacter pylori -negative Stomach","authors":"S. Sasaki, J. Nishikawa, M. Nagao, R. Ogawa, Atsushi Goto, Shinichi Hashimoto, T. Okamoto, Chieko Suzuki, Y. Hoshii, I. Sakaida","doi":"10.2342/YMJ.66.41","DOIUrl":"https://doi.org/10.2342/YMJ.66.41","url":null,"abstract":"","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"380 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116326061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
症例報告 胸水ADAが高値を示し,結核性胸膜炎との鑑別を要した胸膜原発悪性リンパ腫の1例 病例报告胸水ADA高，需鉴别为结核性胸膜炎的1例胸膜原发恶性淋巴瘤
Yamaguchi Medical Journal Pub Date : 2016-11-01 DOI: 10.2342/YMJ.65.161
村田 順之, 青江 啓介, 利彰 宇都宮, 坂本 健次, 大石 景士, 神徳 済, 近森 研一, 前田 忠士, 岡部 和倫, 村上 知之, 矢野 雅文, 上岡 博
{"title":"症例報告 胸水ADAが高値を示し,結核性胸膜炎との鑑別を要した胸膜原発悪性リンパ腫の1例","authors":"村田 順之, 青江 啓介, 利彰 宇都宮, 坂本 健次, 大石 景士, 神徳 済, 近森 研一, 前田 忠士, 岡部 和倫, 村上 知之, 矢野 雅文, 上岡 博","doi":"10.2342/YMJ.65.161","DOIUrl":"https://doi.org/10.2342/YMJ.65.161","url":null,"abstract":"","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123053456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cell-Free and Concentrated Pleural Effusion Reinfusion Therapy Using an Intrathoracic Catheter Subcutaneous Port System Can Achieve a Long-Term Home Care for a Patient with Refractory Pleural Effusion in Lung Cancer 无细胞浓缩胸腔积液再输注胸腔内导管皮下系统可实现肺癌难治性胸腔积液患者的长期家庭护理
Yamaguchi Medical Journal Pub Date : 2016-11-01 DOI: 10.2342/YMJ.65.167
Kana Takeuchi, N. Takahashi, Noriko Hiyama, Hiroyuki Watanabe
{"title":"Cell-Free and Concentrated Pleural Effusion Reinfusion Therapy Using an Intrathoracic Catheter Subcutaneous Port System Can Achieve a Long-Term Home Care for a Patient with Refractory Pleural Effusion in Lung Cancer","authors":"Kana Takeuchi, N. Takahashi, Noriko Hiyama, Hiroyuki Watanabe","doi":"10.2342/YMJ.65.167","DOIUrl":"https://doi.org/10.2342/YMJ.65.167","url":null,"abstract":"","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128846305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
75歳以上高齢者の進行･再発大腸癌に対するベバシズマブ+XELOX療法の検討 针对75岁以上老年人的晚期、复发大肠癌的贝瓦西单抗+XELOX疗法的讨论
Yamaguchi Medical Journal Pub Date : 2016-05-01 DOI: 10.2342/YMJ.65.87
久保 秀文, 長岡 知里, 多田 耕輔, 宮原 誠, 博康 長谷川
{"title":"75歳以上高齢者の進行･再発大腸癌に対するベバシズマブ+XELOX療法の検討","authors":"久保 秀文, 長岡 知里, 多田 耕輔, 宮原 誠, 博康 長谷川","doi":"10.2342/YMJ.65.87","DOIUrl":"https://doi.org/10.2342/YMJ.65.87","url":null,"abstract":"","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128623606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Tracing the History of Medical Therapies to the Development of Novel Therapies for Hepatocellular Carcinoma 从医学治疗的历史追溯到肝癌新疗法的发展
Yamaguchi Medical Journal Pub Date : 2016-02-01 DOI: 10.2342/YMJ.65.15
T. Yamasaki
{"title":"From Tracing the History of Medical Therapies to the Development of Novel Therapies for Hepatocellular Carcinoma","authors":"T. Yamasaki","doi":"10.2342/YMJ.65.15","DOIUrl":"https://doi.org/10.2342/YMJ.65.15","url":null,"abstract":"","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114340602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
「その人に最善のケア」を創造するために基本的なこと：看護の判断に迷った臨地実習中の看護学生への指導の一経験を質的に分析する 创造“对那个人最好的照顾”的基本:对在护理判断中犹豫的临时实习中的护理学生的指导经验进行质的分析。
Yamaguchi Medical Journal Pub Date : 2016-02-01 DOI: 10.2342/YMJ.65.39
正村 啓子
{"title":"「その人に最善のケア」を創造するために基本的なこと：看護の判断に迷った臨地実習中の看護学生への指導の一経験を質的に分析する","authors":"正村 啓子","doi":"10.2342/YMJ.65.39","DOIUrl":"https://doi.org/10.2342/YMJ.65.39","url":null,"abstract":"","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121726244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interferonβ＋ribavirin併用療法によりsustained virological responseが得らたCharcot-Marie-Tooth病合併C型慢性肝炎の一例 通过Interferonβ + ribavirin联合疗法获得sustained virological response的Charcot-Marie-Tooth病合并C型慢性肝炎的一个例子
Yamaguchi Medical Journal Pub Date : 2016-02-01 DOI: 10.2342/YMJ.64.53
桂司 松浦, 勲 日髙, 忠相 花園, 一成 佐伯, 拓也 岩本, 剛 石川, 太郎 高見, 元晴 川井, 崇二 寺井, 隆善 神田, 功 坂井田
{"title":"Interferonβ＋ribavirin併用療法によりsustained virological responseが得らたCharcot-Marie-Tooth病合併C型慢性肝炎の一例","authors":"桂司 松浦, 勲 日髙, 忠相 花園, 一成 佐伯, 拓也 岩本, 剛 石川, 太郎 高見, 元晴 川井, 崇二 寺井, 隆善 神田, 功 坂井田","doi":"10.2342/YMJ.64.53","DOIUrl":"https://doi.org/10.2342/YMJ.64.53","url":null,"abstract":"","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"2012 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128064194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe Fever with Thrombocytopenia Syndrome（SFTS） 发热伴血小板减少综合征(SFTS)
Yamaguchi Medical Journal Pub Date : 2016-02-01 DOI: 10.2342/YMJ.65.31
Toru Takahashi
{"title":"Severe Fever with Thrombocytopenia Syndrome（SFTS）","authors":"Toru Takahashi","doi":"10.2342/YMJ.65.31","DOIUrl":"https://doi.org/10.2342/YMJ.65.31","url":null,"abstract":"","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128416828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
MAID (Mesna, Adriamycin, Ifosfamide, Dacarbazine) Combination Chemotherapy in a Patient with Angiosarcoma of the Skin MAID (Mesna，阿霉素，异环磷酰胺，达卡巴嗪)联合化疗治疗1例皮肤血管肉瘤患者
Yamaguchi Medical Journal Pub Date : 2015-08-01 DOI: 10.2342/YMJ.64.199
Y. Kurata, K. Wakamatu, Yoshitaka Nakamura, M. Ichimiya, M. Muto
{"title":"MAID (Mesna, Adriamycin, Ifosfamide, Dacarbazine) Combination Chemotherapy in a Patient with Angiosarcoma of the Skin","authors":"Y. Kurata, K. Wakamatu, Yoshitaka Nakamura, M. Ichimiya, M. Muto","doi":"10.2342/YMJ.64.199","DOIUrl":"https://doi.org/10.2342/YMJ.64.199","url":null,"abstract":"","PeriodicalId":166832,"journal":{"name":"Yamaguchi Medical Journal","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125626964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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