Journal of oral pathology最新文献_第4页

Effect of snuff and herpes simplex virus-1 on rat oral mucosa: possible associations with the development of squamous cell carcinoma. 鼻烟和单纯疱疹病毒-1 对大鼠口腔黏膜的影响：可能与鳞状细胞癌的发展有关。

Journal of oral pathology Pub Date : 1984-02-01 DOI: 10.1111/j.1600-0714.1984.tb01400.x

J M Hirsch, S L Johansson, A Vahlne

{"title":"Effect of snuff and herpes simplex virus-1 on rat oral mucosa: possible associations with the development of squamous cell carcinoma.","authors":"J M Hirsch, S L Johansson, A Vahlne","doi":"10.1111/j.1600-0714.1984.tb01400.x","DOIUrl":"10.1111/j.1600-0714.1984.tb01400.x","url":null,"abstract":"The purpose of this investigation was to study the effect of snuff and experimentally induced herpes simplex virus type 1 (HSV-1) infection in Sprague-Dawley rats. It was demonstrated that it was possible to obtain 100% development of acute HSV-1 infection in the rat oral mucosa, but only 10% of latent reactive infection of the trigeminal ganglia. The rats were, therefore, acutely infected monthly with virus to simulate recurrence of latent infection. Virus was applied topically to the mucous membrane twice with an interval of one month. Snuff was administered between the virus applications and afterwards to half the virus-exposed animals. Sham-infected rats were given snuff during the same period (18 months). A fourth group of rats were left untreated. A complete post-mortem examination was performed. Two rats exposed to snuff and HSV-1 in combination developed squamous cell carcinoma of the oral cavity. It was also found that rats exposed to snuff alone or in combination with HSV-1 had a higher incidence of tumours or tumour-like conditions than control rats exposed to HSV-1 only. The incidence of malignant tumours was significantly higher in rats exposed to snuff or HSV-1 and snuff in combination than in control animals (p less than 0.05). The results of the study indicate that HSV-1 in combination with snuff exposure may be associated with the development of squamous cell carcinomas of the oral cavity.","PeriodicalId":16672,"journal":{"name":"Journal of oral pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1984-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1600-0714.1984.tb01400.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17382793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 65

The alleged radioresistance of ameloblastoma. 所谓成釉细胞瘤的放射抗性。

Journal of oral pathology Pub Date : 1982-12-01

D G Gardner

引用次数: 0

Oral carcinomas associated with snuff dipping. Some clinical and histological characteristics of 23 tumours in Swedish males. 与蘸鼻烟有关的口腔癌。瑞典男性 23 例肿瘤的一些临床和组织学特征。

Journal of oral pathology Pub Date : 1982-06-01

B Sundström, H Mörnstad, T Axéll

引用次数: 0

Amyloid in a pleomorphic adenoma of the parotid gland. Electron microscopic observations. 腮腺多形性腺瘤中的淀粉样蛋白。电子显微镜观察。

Journal of oral pathology Pub Date : 1981-06-01

B Tandler

引用次数: 0

Plasmacytoid myoepithelioma of the palate. 上颚浆细胞样肌上皮瘤。

Journal of oral pathology Pub Date : 1981-02-01

J M Nesland, J Olafsson, M Sobrinho-Simöes

引用次数: 0

Odontoblast metabolism in rats deficient in vitamin D and calcium. IV. Lysosomal and energy metabolic enzymes. 缺乏维生素D和钙的大鼠成牙细胞代谢。溶酶体和能量代谢酶。

Journal of oral pathology Pub Date : 1980-07-01

C Engström

{"title":"Odontoblast metabolism in rats deficient in vitamin D and calcium. IV. Lysosomal and energy metabolic enzymes.","authors":"C Engström","doi":"","DOIUrl":"","url":null,"abstract":"Young rats, fed a low calcium and vitamin D deficient diet for 2 weeks, developed hypocalcemia, an increased activity of serum alkaline phosphatase and an increase in the serum concentration of immunoreactive parathyroid hormone. An increased activity of lactate dehydrogenase and cytochrome oxidase in odontoblasts was found. No shift in the general energy metabolic pathway was found as visualized in the lactate dehydrogenase iso-enzyme pattern. The dominating lactate dehydrogenase isoenzyme in odontoblasts from both the normal and the deficient rats was LDH 1 (H4, LD5), thus indicating primarily an aerobic energy-metabolism Also the activities of the lysosomal enzymes acid phosphatase, cathepsin D and hyaluronidase in the odontoblasts from the deficient animals were increased when compared to the normal animals. No significant change could be demonstrated for beta-glucuronidase and beta-N-acetylglucosaminidase. It was earlier found that this deficient diet caused an increase in odontoblast alkaline phosphatase activities and protein synthesis in vitro. In view of the present findings it might be concluded that the low calcium and vitamin D deficient diet causes a general increase in the odontoblast metabolism. It is not known whether this is due to the increase in parathyroid hormone or if it is a direct effect of the lowered serum calcium concentration.","PeriodicalId":16672,"journal":{"name":"Journal of oral pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1980-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17318539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathologic and bacterial evaluation of conventional and new copper amalgams. 传统和新型铜汞合金的组织病理学和细菌评价。

Journal of oral pathology Pub Date : 1979-04-01 DOI: 10.1111/j.1600-0714.1979.tb01626.x

D R Heys, C F Cox, R J Heys, W J Loesche, J K Avery

{"title":"Histopathologic and bacterial evaluation of conventional and new copper amalgams.","authors":"D R Heys, C F Cox, R J Heys, W J Loesche, J K Avery","doi":"10.1111/j.1600-0714.1979.tb01626.x","DOIUrl":"https://doi.org/10.1111/j.1600-0714.1979.tb01626.x","url":null,"abstract":"In vivo pulpal responses in monkeys and in vitro bacterial inhibition studies were completed on new copper amalgams, Sybraloy, Dispersalloy, Tytin and a conventional Spheraloy amalgam. Amalgams were placed in cavities lined with ZOE and in unlined cavities. Silicate and ZOE were used as controls. A total of 165 adult monkey teeth were evaluated at 3 days, 5 and 8 weeks. At 3 days the pulpal responses elicited by the copper amalgams appeared similar to conventional Spheraloy, all showing a slight to moderate response. At 5 weeks the majority of amalgams exhibited a slight pulpar response with a tubular reparative dentin under each restoration. The 8 week pulpal response showed a reduction of the inflammatory response characterized by a tubular reparative dentin with a uniform zone of predentin. Lined ZOE controls exhibited a slight response while silicate showed a moderate response with some persistent chronic inflammation. In vitro bacterial tests revealed that the various amalgams had little to no inhibitory effect on the three serotypes of S. mutans that are most prominent in humans.","PeriodicalId":16672,"journal":{"name":"Journal of oral pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1979-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1600-0714.1979.tb01626.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11328015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Topographical distribution of sulphated glycosaminoglycans in human temporomandibular joint disks. A histochemical study of an autopsy material. 硫酸糖胺聚糖在人颞下颌关节盘的地理分布。解剖材料的组织化学研究

Journal of oral pathology Pub Date : 1976-09-01 DOI: 10.1111/j.1600-0714.1976.tb01775.x

S Kopp

{"title":"Topographical distribution of sulphated glycosaminoglycans in human temporomandibular joint disks. A histochemical study of an autopsy material.","authors":"S Kopp","doi":"10.1111/j.1600-0714.1976.tb01775.x","DOIUrl":"https://doi.org/10.1111/j.1600-0714.1976.tb01775.x","url":null,"abstract":"The distribution of sulphated glycosaminoglycans (GAG's) in the human temporomandibular joint disk and its relationship to sex, age and osteoarthrosis was studied by histochemical methods in autopsy material from 18 individuals. The disks were embedded in paraffin and frontal sections, 5-7 mu thick, were cut at different levels. Two staining methods were used, toluidine blue at pH 0.5 and alcian blue with different concentrations of MgCl2. The two methods gave comparable results. The sulphated GAG's as represented by metachromatic staining with toluidine blue at pH 0.5 and staining with alcian blue in concentrations of MgCl2 above 0.55-M were found in the central load-bearing part of the disks evenly distributed in the medio-lateral direction. The findings from the alcian blue staining method indicated the presence of sulphated GAG's with characteristics similar to chondroitin/dermatan sulphate and keratan sulphate. The latter finding was most frequent in a surface zone )10-100 mu) located mainly in the central part of the disks. In macroscopically thin areas of the disks judged as early osteoarthrosis a significant reduction in the staining of sulphated GAG's could be observed. No age or sex differences were found in the distribution of GAG's, either in normal or in osteoarthrotic disks.","PeriodicalId":16672,"journal":{"name":"Journal of oral pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1976-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1600-0714.1976.tb01775.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11283874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 80

The inflammatory infiltrate in lichen planus lesions. An autoradiographic and ultrastructural study. 扁平苔藓病变处的炎性浸润。放射自显影和超微结构研究。

Journal of oral pathology Pub Date : 1976-09-01 DOI: 10.1111/j.1600-0714.1976.tb01776.x

D M Walker

引用次数: 33

Atrophic lesions of the tongue: a prevalence study among 175 diabetic patients. 舌萎缩性病变:175例糖尿病患者的患病率研究。

Journal of oral pathology Pub Date : 1976-09-01 DOI: 10.1111/j.1600-0714.1976.tb01774.x

A G Farman

引用次数: 59