Journal of paediatrics and child health最新文献_第6页

Targeted Therapies in Paediatric Low-Grade Gliomas: Shifting the Neurosurgical Paradigm in Optic Pathway Gliomas. 儿科低级别胶质瘤的靶向治疗：改变视神经通路胶质瘤的神经外科范式。

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 Epub Date: 2026-09-25 DOI: 10.1111/jpc.70609

Danielly Ferreira Mendes, Leonardo Pereira Levada, Maria Letícia Lisboa Gomes, Reinaldo Couri Nogueira Junior

引用次数: 0

Safe Sleep Education Blitz: A Pre-Post Survey Study. 安全睡眠教育闪电战：一项前后调查研究。

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 DOI: 10.1111/jpc.70612

Nina Sivertsen, Charlene Thornton, Sharon Watts, Anna Dowling, Tahlia Johnson, Janiene Deverix, Susan Dyer, Wilhelmine Lieberwirth, Alice Steeb, Susan Smith, Julian Grant

{"title":"Safe Sleep Education Blitz: A Pre-Post Survey Study.","authors":"Nina Sivertsen, Charlene Thornton, Sharon Watts, Anna Dowling, Tahlia Johnson, Janiene Deverix, Susan Dyer, Wilhelmine Lieberwirth, Alice Steeb, Susan Smith, Julian Grant","doi":"10.1111/jpc.70612","DOIUrl":"https://doi.org/10.1111/jpc.70612","url":null,"abstract":"In response to ongoing concerns about Sudden Unexpected Death in Infancy (SUDI) amongst Aboriginal and Torres Strait Islander infants, a targeted safe sleep education package which adopted Aboriginal culturally appropriate language was delivered to health professionals working with Aboriginal and Torres Strait Islander families. This initiative accompanied the rollout of the Pēpi-Pod as a culturally responsive safe sleep alternative. The aim of this study was to conduct a safe sleep education blitz to health professionals to evaluate the effectiveness of the education blitz in enhancing clinical knowledge of safe sleep practices. Surveys were administered to health professionals both before and after the education blitz to assess changes in knowledge and evaluate the effectiveness of the intervention. The mean knowledge score increased from 8.6 (SD = 2.56) pre-intervention to 9.5 (SD = 1.22) post-intervention, indicating a positive trend in knowledge acquisition. However, this improvement was not statistically significant. The most notable improvement was seen in responses to the question, \"What weakens a baby's arousal response?\" where correct answers increased from 83% pre-intervention to 100% post-intervention. The education blitz proved to be promising in enhancing safe sleep knowledge and increasing awareness of the Pēpi-Pod Program as a safe sleep alternative. While health and care professionals demonstrated a high level of understanding, particularly regarding infant arousal and breathing physiology, further improvement could be achieved through continued access to the education blitz. Further evaluation with a larger sample size or over longer time frames is required to confirm these findings.","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cavernous Haemangioma of the Knee Joint Mimicking Juvenile Idiopathic Arthritis. 模拟幼年特发性关节炎的膝关节海绵状血管瘤。

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 Epub Date: 2026-08-12 DOI: 10.1111/jpc.70539

Elif Erorhan, Fatma Aydın, Ömer Suat Fitoz, Pınar Özge Avar Aydın, Mustafa Onur Karaca, Zeynep Birsin Özçakar

引用次数: 0

Feasibility of Percutaneous Endoscopic Gastrostomy Tube Placement in Infants Weighing Less Than 2 kg: A Case Series From Eastern India. 经皮内镜胃造口管置入体重小于2公斤婴儿的可行性：来自印度东部的病例系列。

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 Epub Date: 2026-09-02 DOI: 10.1111/jpc.70547

Sarthak Chakrabarti, Rajat Khandelwal, Sourish Kumar Roy, Uday Chand Ghoshal, Mahesh Kumar Goenka, Amrita Roy

引用次数: 0

Therapeutic Hypothermia Modulates S100B and Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy: Implications of SDF4 as a Novel Biomarker. 治疗性低温调节新生儿缺氧缺血性脑病的S100B和氧化应激：SDF4作为一种新的生物标志物的意义

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 Epub Date: 2026-08-28 DOI: 10.1111/jpc.70545

Fatih Isleyen, Celil Yilmaz, Ismail Koyuncu

{"title":"Therapeutic Hypothermia Modulates S100B and Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy: Implications of SDF4 as a Novel Biomarker.","authors":"Fatih Isleyen, Celil Yilmaz, Ismail Koyuncu","doi":"10.1111/jpc.70545","DOIUrl":"10.1111/jpc.70545","url":null,"abstract":"Aim: This study investigated the dynamic profile of stromal cell-derived factor 4 (SDF4), a hypoxia-inducible chemokine and S100B, an established astroglial injury marker, in neonates with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). Its potential as a biomarker was assessed by examining its relationship with baseline severity, clinical trajectories and metabolic recovery.Methods: In this prospective cohort study, 33 term neonates with moderate-to-severe HIE treated with TH and 20 healthy controls were enrolled. Serum levels of SDF4, S100B, total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI) and thiol-disulphide homeostasis were measured before TH (baseline) and on Day 5 (after rewarming). Effect sizes (Cohen's d) were calculated for significant results.Results: Before TH, HIE infants had significantly higher SDF4, S100B, OSI and disulphide levels and lower native thiol and TAS than controls (all p < 0.01). Following TH, all six biomarkers changed significantly in the anticipated direction across the total cohort (all p ≤ 0.020). In stage-specific sub-analysis, post-TH reductions in SDF4 and S100B were statistically significant only in Stage 2 HIE (p = 0.013 and p = 0.030, respectively), whereas oxidative stress parameters (OSI, native thiol, TAS) improved significantly in both severity groups.Conclusion: SDF4 appears to be a novel biomarker reflecting both HIE severity and the dynamic response to TH. The selective lack of SDF4 and S100B clearance in Stage 3 HIE highlights a more sustained pattern of neuroinflammatory injury, supporting SDF4's potential role in monitoring metabolic recovery and guiding individualised neuroprotective strategies.","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":"2019-2028"},"PeriodicalIF":1.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Monosymptomatic Nocturnal Enuresis in Children: A Pilot Randomised Control Trial of Body-Worn Versus Bell-and-Pad Alarm Device. 儿童单症状性夜间遗尿的管理：一项随身携带与铃垫报警装置的随机对照试验。

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 Epub Date: 2026-08-25 DOI: 10.1111/jpc.70543

Blake Peck, Daniel Terry, Bronwyn Peck, Andrea Green, Kerrie Svedas, Shirley Whitaker, Monica Harrop, Erica Pearce, Mark Nethercote, Natasha Burgess, Ha N D Le, Sithara Wanni Arachchige Dona, Susan Gibb

{"title":"Management of Monosymptomatic Nocturnal Enuresis in Children: A Pilot Randomised Control Trial of Body-Worn Versus Bell-and-Pad Alarm Device.","authors":"Blake Peck, Daniel Terry, Bronwyn Peck, Andrea Green, Kerrie Svedas, Shirley Whitaker, Monica Harrop, Erica Pearce, Mark Nethercote, Natasha Burgess, Ha N D Le, Sithara Wanni Arachchige Dona, Susan Gibb","doi":"10.1111/jpc.70543","DOIUrl":"10.1111/jpc.70543","url":null,"abstract":"Aim: To compare bell-and-pad alarm therapy to body-worn alarm therapy for the management of monosymptomatic enuresis in children 6-16 years of age in Victoria, Australia.Method: A sample of 76 children with monosymptomatic enuresis were randomly allocated to a control group (bell-and-pad alarm, n = 38) or an experimental group (body-worn alarm, n = 38). All children were treated for 8 weeks. Children who had not been successful, defined as 14 consecutive dry nights, continued therapy up to 16 weeks. The two alarm types were compared using dichotomous cross-tabulations and chi-squared tests of independence based on the most positive outcome versus the other outcomes. The costs of the treatment were calculated from the service provider's and family's perspective. Costs were in 2023 Australian dollars.Results: Treatment success was achieved in 22 children (68.7%) in the body-worn alarm group and 34 children (94.4%) in the routine (bell-and-pad) group (p = 0.010). The bell-and-pad alarm also performed better on three other indicators: Alarm used every night (p = 0.018), alarm woke parent (p = 0.011), and child was compliant with alarm use (p = 0.015). The body-worn treatment was found to be cheaper than the bell-and-pad treatment ($598 per child) but was not as effective.Conclusion: The success rates for treatment were high in both groups but the bell-and-pad alarm was found to be more effective than the body-worn alarm used in this study. Further research is recommended, with a larger population, to establish more definitive support for clinical decision making.Trial registration: Australian and New Zealand Clinical Trials Registry ACTRN12619000354189.","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":"2012-2018"},"PeriodicalIF":1.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cefiderocol as Salvage Therapy in Difficult-to-Treat Resistant (DTR) Pseudomonas aeruginosa Complicated Central Nervous System Infection. 头孢地罗作为难治性耐药（DTR）铜绿假单胞菌合并中枢神经系统感染的挽救治疗。

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 Epub Date: 2026-08-12 DOI: 10.1111/jpc.70520

Olivia M Y Leow, Rie Aoyama, Nwoshin Jahan, Vincent Nga, Hian Tat Ong, Kelvin K K Goh, Andrea L H Kwa, Tze Peng Lim, Gabriel Z R Yan, Si Min Chan

引用次数: 0

Efficacy and Safety of Upadacitinib in Refractory Very-Early-Onset Ulcerative Colitis: A Case Report. Upadacitinib治疗难治性早发性溃疡性结肠炎的疗效和安全性：1例报告。

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 Epub Date: 2026-08-23 DOI: 10.1111/jpc.70544

Elijah Ze Xian Khaw, Kee Seang Chew, Norashikin Mohd Ranai, Ruey Terng Ng, Way Seah Lee

引用次数: 0

Comfort as Core Care in Therapeutic Advancements of Paediatric Neurology. 舒适是儿科神经病学治疗进展的核心护理。

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 Epub Date: 2026-09-21 DOI: 10.1111/jpc.70600

Monica S Cooper, Claire Prowse, Michael C Fahey

引用次数: 0

Behavioural Problems in Developmental Disorders: A Paediatrician's Guide. 发育障碍中的行为问题：儿科医生指南。

IF 1.4 4区医学

Journal of paediatrics and child health Pub Date : 2026-10-01 Epub Date: 2026-09-30 DOI: 10.1111/jpc.70592

Daryl Efron

引用次数: 0