Andrew Gorrie, Natalie Tannos, Dean Morris, Andrew Leicester, Jeffrey S Ling, Arnold Suzuki, Samya Lakis
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引用次数: 0
Abstract
Backgrounds: There is no consensus if a relationship exists between idiopathic congenital talipes equinovarus (CTEV) and developmental dysplasia of the hip (DDH). Our research aim was to provide a contemporary Australian population statistical relationship between DDH and idiopathic CTEV, compared to published data.
Methods: We conducted a retrospective data analysis of a continuous sample of infants with idiopathic CTEV, who attended a Ponseti Clinic at Sydney Children's Hospital, born between 2010 and 2019. The prevalence of DDH requiring treatment was diagnosed utilising screening ultrasonography and compared to the most valid population data from Australia. The relative risk compared to this data was also determined.
Results: There were 250 subjects who met the inclusion criteria and had complete datasets for analysis. The prevalence of DDH in our idiopathic CTEV study population was 52.9 (95% CI 27.6-90.5) per 1000. This represents a higher prevalence rate than Western Australian and South Australian datasets, with 9.5 (95% CI 8.9-10.1) and 5.0 (95% CI 4.6-5.5) per 1000, respectively. The relative risk of DDH in our idiopathic CTEV study population was 5.59 (95% CI 3.21-9.73, p < 0.0001) and 10.50 (95% CI 6.01-18.34, p < 0.0001), compared to Western Australian and South Australian population datasets, respectively.
Conclusion: Our study findings support a positive correlation between idiopathic CTEV and DDH. The relative risk of DDH in the idiopathic CTEV population is 5-10 times higher than the general Australian population. When selective hip ultrasound screening is used, we believe idiopathic CTEV should be considered a risk factor for DDH.
背景:特发性先天性马蹄内翻(CTEV)与髋关节发育不良(DDH)之间是否存在关系尚无共识。我们的研究目的是提供当代澳大利亚人口DDH和特发性CTEV之间的统计关系,并与已发表的数据进行比较。方法:我们对2010年至2019年在悉尼儿童医院Ponseti诊所就诊的特发性CTEV婴儿的连续样本进行了回顾性数据分析。需要治疗的DDH患病率是利用超声筛查诊断的,并与澳大利亚最有效的人口数据进行了比较。与此数据相比,也确定了相对风险。结果:有250名受试者符合纳入标准,有完整的数据集供分析。在我们的特发性CTEV研究人群中,DDH的患病率为52.9 / 1000 (95% CI 27.6-90.5)。这代表了比西澳大利亚和南澳大利亚数据集更高的患病率,分别为每1000人9.5 (95% CI 8.9-10.1)和5.0 (95% CI 4.6-5.5)。在我们的特发性CTEV研究人群中,DDH的相对风险为5.59 (95% CI 3.21-9.73, p)。结论:我们的研究结果支持特发性CTEV与DDH之间的正相关。特发性CTEV人群DDH的相对危险性是澳大利亚普通人群的5-10倍。当使用选择性髋关节超声筛查时,我们认为特发性CTEV应被视为DDH的危险因素。
期刊介绍:
The Journal of Paediatrics and Child Health publishes original research articles of scientific excellence in paediatrics and child health. Research Articles, Case Reports and Letters to the Editor are published, together with invited Reviews, Annotations, Editorial Comments and manuscripts of educational interest.