Journal of paediatrics and child health最新文献

{"title":"Medicinal Cannabis for Emotional and Behavioural Symptoms: Parent and Physician Perspectives.","authors":"Corey Driscoll, Kaitlyn Taylor, Cecilia Moore, Chidambaram Prakash, Daryl Efron","doi":"10.1111/jpc.70048","DOIUrl":"https://doi.org/10.1111/jpc.70048","url":null,"abstract":"","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Primitive Reflexes in Early Childhood as a Potential Biomarker for Developmental Disabilities.","authors":"Gerry Leisman, Robert Melillo","doi":"10.1111/jpc.70053","DOIUrl":"https://doi.org/10.1111/jpc.70053","url":null,"abstract":"<p><p>We aim to understand better the significance of retained primitive reflexes (RPRs) and examine the effect of RPRs in children, adolescents, and adults, focusing on autism spectrum disorder (ASD) and other neurodevelopmental conditions, as well as examine a basis for future treatment alternatives. We included a history section to better recognise the way that the scientific and medical communities have studied and understood the importance of RPRs. We review findings indicating that aspects of these disorders are related to the presence of functional disconnectivities related to a cortical maturational effect on neuronal networks. Cortical maturational delay within specific networks may lead to enhanced growth and maturation in other networks, resulting in asynchronous development and inconsistency in functional skills. There has been reported an overconnectivity of short-range, more immature connections and an underconnectivity of long-range, more mature connectivities. We review the relationship between motor and cognitive impairments and RPRs. A crucial conclusion will be that inhibiting these RPRs is representative of treatment targets.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late Nutrition and Negative Outcomes in a Brazilian Paediatric Intensive Care Unit: A Retrospective Cohort.","authors":"Arnildo Linck Júnior, Flávia Lopes Gabani, Edmarlon Girotto, Ana Maria Rigo Silva, Selma Maffei de Andrade","doi":"10.1111/jpc.70049","DOIUrl":"https://doi.org/10.1111/jpc.70049","url":null,"abstract":"<p><strong>Aim: </strong>To analyse the association between late initiation of enteral nutrition and negative outcomes in the Paediatric Intensive Care Unit (PICU) in Brazil.</p><p><strong>Method: </strong>This was a retrospective cohort study with data from the medical records of children hospitalised between 2012 and 2017. The independent variable was late initiation of enteral nutrition (> 24 h after admission). The outcomes analysed included longer length of stay in the PICU and hospital, incidence of healthcare-related infections (HAIs), and death. Poisson regression models with robust variance were adjusted for potentially confounding variables by presenting relative risks (RR) and 95% confidence intervals (95% CI).</p><p><strong>Results: </strong>We analysed 840 hospitalizations: 311 (37.0%) with delayed initiation of nutrition, 252 (30.0%) with a diagnosis of HAIs, and 93 deaths (11.1%). After all adjustments, late initiation of enteral nutrition was associated with longer lengths of stay in the PICU (RR: 1.41; 95% CI: 1.01-1.30), hospital stay (RR: 1.22; 95% CI: 1.06-1.41), and higher HAI incidence (RR: 1.40; 95% CI: 1.14-1.73). The association with mortality was no longer significant after adjusting for the admission severity indicators.</p><p><strong>Conclusion: </strong>The results indicate that late initiation of nutrition can lead to longer PICU and hospital stays and a higher incidence of HAIs.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in the Diagnosis and Treatment of Paediatric Endocrine Disorders.","authors":"Lara E Graves, Benjamin Wheeler","doi":"10.1111/jpc.70047","DOIUrl":"https://doi.org/10.1111/jpc.70047","url":null,"abstract":"","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Burden of Paediatric Supracondylar Humeral Fractures Admitted Within a Health Region in New Zealand.","authors":"Evangeline Liddicoat, Sheena Moosa, Alastair Smith, Grant Christey","doi":"10.1111/jpc.70045","DOIUrl":"https://doi.org/10.1111/jpc.70045","url":null,"abstract":"<p><strong>Introduction: </strong>Supracondylar humeral fractures (SCHF) comprise the majority of all paediatric elbow injuries and most require surgical intervention. This study determines the incidence and outcomes of SCHF in children of all injury severities admitted to hospital over 10 years in a health region of Aotearoa New Zealand (AoNZ).</p><p><strong>Materials and methods: </strong>Retrospective data from Te Manawa Taki (TMT) Trauma Registry was extracted for all paediatric trauma hospitalisations (aged 0-14 years) with SCHF from 1 January 2012 to 31 December 2022. Patients with SCHF were identified using the International Classification of Disease-10 primary cause codes. Demographic and injury characteristics with hospital costs were analysed.</p><p><strong>Results: </strong>Paediatric SCHF (n = 1563) incidence was 73.7/100 000 (CI 61.5-85.8). Majority (62.8%) were aged 5-9 years with an incidence rate of 131.5/100 000 (CI 104.2-158.8). They were 6.6 and 2.0 times more frequently hospitalised than 10-14 and 0-4 year olds. The most common place for injury was home (40.9%) followed by school, other institution and public administrative area (32.5%). Falls accounted for 91.7% of injuries with most (52.4%) occurring at a height of less than 1 m. The majority (76.2%) of patients spent 1 day in hospital and over three quarters had operative management. Estimated hospital costs were $9 842 587 total with an average cost of $6354 per admission. There was no significant difference in annual incidence over time.</p><p><strong>Conclusion: </strong>Paediatric SCHF is a significant issue in AoNZ, particularly in those aged 5-9 years. There is a clear need for injury prevention interventions in the home and school to minimise falls and reduce healthcare costs.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric Emergency Department Mental Health and Behavioural Presentations in Australia Before and After the Onset of the COVID-19 Pandemic: Retrospective Observational Study.","authors":"Jackson Newberry-Dupe, Glenn Melvin, Kylie King, Marietta John White, Vicki Anderson, Franz E Babl, Meredith L Borland, Stuart R Dalziel, Harriet Hiscock, Bruce J Tonge, Paul Buntine, Brooke Charters, Megan Hamilton, Amit Kochar, Alastair Meyer, Viet Tran, Emogene Aldridge, Giles Barrington, Liam Hackett, Nicole Lowry, Joseph Miller, Sebastian Wrobel, Rohan Borschmann, Simon Craig","doi":"10.1111/jpc.70046","DOIUrl":"https://doi.org/10.1111/jpc.70046","url":null,"abstract":"<p><strong>Objectives: </strong>Although child and adolescent mental health and behavioural presentations to hospital emergency departments (EDs) increased during the first 2 years of the COVID-19 pandemic (2020 and 2021), little is known about the characteristics of these presentations. We aimed to compare demographic, clinical and psychosocial profiles of paediatric presentations to Australian EDs before and after the onset of the pandemic.</p><p><strong>Methods: </strong>We conducted a retrospective observational study of 100 randomly sampled presentations by children (6-11-year-olds) and adolescents (12-17-year-olds) to 10 Australian EDs between 1 January and 31 December 2019 (pre-COVID-19) and 1 January and 31 December 2021 (COVID-19). Using a multilevel factor model, we compared the pre-COVID-19 and COVID-19 cohorts regarding demographic characteristics, diagnoses, precipitants, time-to-treatment, length of stay, and discharge disposition.</p><p><strong>Results: </strong>The COVID-19 period was characterised by increased presentations by adolescents and girls. Compared to the pre-COVID-19 cohort, the COVID-19 cohort experienced increased median waiting times (48 and 72 min, respectively), median length of ED stay (4.7 and 5.4 h), and likelihood of admissions to the ED short stay unit (9.5% and 12.9%). Patients in the COVID-19 cohort were more likely to present with self-harm and suicidal thoughts/behaviours, eating disorders, neurodevelopmental and neurocognitive disorders, and psychosocial stressors, and less likely to have diagnoses of disruptive behaviour, impulse control, and conduct disorders.</p><p><strong>Conclusions: </strong>Young people presenting to the ED in 2021 for mental health reasons were more likely to wait longer, stay longer, have a diagnosis of intentional self-harm and/or a neurodevelopmental disorder, and report psychosocial stressors.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Electronic Devices on Children's Behaviour.","authors":"Najlaa Ibrahim Al-Sammak, Muhammad Ahmad Younis, Abdulrhman Akram Abdulrhman, Manahil Ammar Thanoon, Ubayda Abdulsattar Salim, Redhaa Muthanna Khalil, Hiba Thamer Muhammed","doi":"10.1111/jpc.70043","DOIUrl":"https://doi.org/10.1111/jpc.70043","url":null,"abstract":"<p><strong>Aim: </strong>One of the main advances today is the development of electronic devices and their applications. They eased human life, but adversely impacted their psych and social relationships. Children, the sensitive part of human development, become involved in these quandaries. So, this study aimed to determine the effects of these devices on childhood behaviours in Mosul/Iraq.</p><p><strong>Methods: </strong>A cross-sectional study was applied on parents' of 1102 children whose ages range 1-15 years. They were chosen conveniently from public places in Mosul over a period of 6 months since December 2023. A self-administered questionnaires were filled by those parents taking their opinions about the benefits and drawbacks of electronic devices on their children. The latter were divided into three comparable groups according to the duration of use. The collected data were analysed by SPSS using the Goodness of Fit test for exploring the significance of comparison.</p><p><strong>Results: </strong>Mean age of studied children was 9.3 years, half of them (50.9%) used devices for three or more years, and another half (49.3%) had three or more hours of daily use. Parents said that their children's language and educational commitments were promoted by electronic devices, but unfortunately, they significantly suffered from anger, stubbornness, aggressiveness and sleep disturbances, especially after prolonged use (p < 0.001) for each variable.</p><p><strong>Conclusion: </strong>Although digital devices enhanced the learning abilities of children, they impacted their psych and real communication adversely. So, to protect them, children should have limited time and types of applications used in order to positively promote their wellbeing.</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FeBRILe3: Risk-Stratification and Diagnosis of Serious Bacterial Infections in Febrile Infants Less Than 3 Months Old.","authors":"Ariel O Mace, Jessica Ramsay, James Totterdell, Andrew C Martin, Julie Barnett, Jade Ferullo, Briony Hazelton, Paul Ingram, Julie A Marsh, Peter Richmond, Yue Wu, Thomas L Snelling","doi":"10.1111/jpc.70041","DOIUrl":"https://doi.org/10.1111/jpc.70041","url":null,"abstract":"<p><strong>Objectives: </strong>Evidence-based recommendations exist for early discharge (before 48 h) of young infants with fever without source (FWS) at low risk of serious bacterial infections (SBIs). However, concerns regarding the applicability of international data to local contexts may hinder implementation. We aimed to describe the local epidemiology of FWS and evaluate a newly implemented risk-stratification guideline to support practice change.</p><p><strong>Methods: </strong>Prospective observational study of infants aged < 3 months admitted for investigation and management of FWS to two hospitals in Perth, Western Australia following implementation of an FWS risk-stratification guideline (August 2019-December 2021). We assessed the risk-stratification rule performance and determined the positive/negative likelihood ratios of individual patient characteristics for predicting SBI diagnosis.</p><p><strong>Results: </strong>Five hundred infants were enrolled in the study cohort (median age 34 days, 36% female). SBI was diagnosed in 159 infants (32%), including urinary tract infection (n = 140), bacteraemia (n = 18) and bacterial meningitis (n = 9). Viruses were detected in 174 out of 406 tested infants (43%). Seventy-one infants met low-risk criteria (14%); only 69 out of 360 infants without SBI were classified as low risk (19%). The risk-stratification criteria demonstrated 99% sensitivity and 97% negative predictive value for SBI diagnosis, but only 21% specificity. Patient characteristics associated with a reduced likelihood of SBI diagnosis included female sex, sick contact exposure and virus detection.</p><p><strong>Conclusions: </strong>Meeting the low-risk criteria successfully excluded most infants with SBI; however, only a small proportion of infants without SBI fulfilled these criteria. Integrating additional patient characteristics into updated risk-stratification algorithms may improve the predictive value of future prediction tools.</p><p><strong>Trial registration: </strong>Australia and New Zealand Clinical Trials Register (ACTRN12619001010189).</p>","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Lamellar Ichthyosis in a 10-Year-Old Child With Secukinumab.","authors":"Roberto Mazzetto, Francesca Caroppo, Elisa Milan, Fortunato Cassalia, Anna Belloni Fortina","doi":"10.1111/jpc.70044","DOIUrl":"https://doi.org/10.1111/jpc.70044","url":null,"abstract":"","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PSANZ 2025 Oral","authors":"","doi":"10.1111/jpc.70008","DOIUrl":"https://doi.org/10.1111/jpc.70008","url":null,"abstract":"","PeriodicalId":16648,"journal":{"name":"Journal of paediatrics and child health","volume":"61 S1","pages":"6-40"},"PeriodicalIF":1.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}