Journal of oral science最新文献

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Masticatory performance with one missing molar. 缺失一颗臼齿的咀嚼性能。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-08-10 DOI: 10.2334/josnusd.23-0212
Masaoki Yokoyama, Hiroshi Shiga, Kunihisa Nakajima, Hanako Uesugi, Marie Komino, Mako Sano, Akira Takakusaki, Yukinori Iwanami, Kenichiro Kojima, Etsuro Hanawa
{"title":"Masticatory performance with one missing molar.","authors":"Masaoki Yokoyama,&nbsp;Hiroshi Shiga,&nbsp;Kunihisa Nakajima,&nbsp;Hanako Uesugi,&nbsp;Marie Komino,&nbsp;Mako Sano,&nbsp;Akira Takakusaki,&nbsp;Yukinori Iwanami,&nbsp;Kenichiro Kojima,&nbsp;Etsuro Hanawa","doi":"10.2334/josnusd.23-0212","DOIUrl":"10.2334/josnusd.23-0212","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate masticatory performance in cases where one molar was missing.</p><p><strong>Methods: </strong>Participants were 156 adults with one molar missing from their natural teeth, who were divided into group A (without prosthetic treatment) and group B (with prosthetic treatment). The non-missing side was designated as A1 or B1, and the missing side was designated as A2 or B2. The amount of glucose eluted (AG) when the participants chewed a gummy jelly was measured and used as a parameter for masticatory performance. AG was compared between the non-missing side (A1, B1) and missing side (A2, B2), and between the first molar missing group and second molar missing group.</p><p><strong>Results: </strong>AG was significantly greater on the dentate side (P < 0.001) and was significantly less in the A2 group when the first molar was missing (P = 0.002). The rate of decrease of AG was 11.1%, 14.3%, and 8.4% in groups A+B, A, and B, respectively.</p><p><strong>Conclusion: </strong>Masticatory performance appears to decrease even with only one missing molar. Although improvement is achieved by prosthetic treatment, performance remains inferior to that on the dentate side.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9967162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of the HBW Ultrasonic Ring for retrieval of fragmented manual or rotatory instruments. HBW超声环用于回收零散手动或旋转器械的疗效。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-08-10 DOI: 10.2334/josnusd.23-0031
Jennifer Galván-Pacheco, Verónica Méndez-González, Ana González-Amaro, Heriberto Bujanda-Wong, Amaury Pozos-Guillén, Arturo Garrocho-Rangel
{"title":"Efficacy of the HBW Ultrasonic Ring for retrieval of fragmented manual or rotatory instruments.","authors":"Jennifer Galván-Pacheco,&nbsp;Verónica Méndez-González,&nbsp;Ana González-Amaro,&nbsp;Heriberto Bujanda-Wong,&nbsp;Amaury Pozos-Guillén,&nbsp;Arturo Garrocho-Rangel","doi":"10.2334/josnusd.23-0031","DOIUrl":"10.2334/josnusd.23-0031","url":null,"abstract":"<p><p>A study was conducted to evaluate the success rates of bypassing or removing fragments of instruments that had fractured within the roots of mandibular molars using a HBW Ultrasonic Ring. Forty extracted first permanent mandibular molars with root canal curvature were included. The teeth were distributed randomly into four groups according to the type of instrument and the root canal third where they had fractured. The success rate for removal of instrument fragments was 100% for both of two stainless steel groups, 90% for a nitinol middle third group, and 80% for a nitinol apical third group. The mean time required for instrument removal was around 40 min. The HBW Ultrasonic Ring showed acceptable experimental results for retrieval of broken instrument fragments.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9969228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The biomechanical stability of miniplate osteosynthesis configurations in bilateral mandibular angle fractures. 微型接骨板在双侧下颌角骨折中的生物力学稳定性。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-08-31 DOI: 10.2334/josnusd.23-0164
Nida Ay, Senem Yildirimturk Dogan, Yigit Sirin
{"title":"The biomechanical stability of miniplate osteosynthesis configurations in bilateral mandibular angle fractures.","authors":"Nida Ay,&nbsp;Senem Yildirimturk Dogan,&nbsp;Yigit Sirin","doi":"10.2334/josnusd.23-0164","DOIUrl":"10.2334/josnusd.23-0164","url":null,"abstract":"<p><strong>Purpose: </strong>The present study investigated the biomechanical stability of three miniplate osteosynthesis configurations used for internal fixation of bilateral mandibular angle fracture (BMAF).</p><p><strong>Methods: </strong>Standard fracture lines were created in 72 polyurethane mandibles and stabilized with 2.0-mm, 4-hole standard titanium miniplates and monocortical screws. The group descriptions and miniplate configurations were: 2Plates (1-1), 3Plates (1-2) and 4Plates (2-2). The mandibles were subjected to either incisal or molar loads (from both sides in the 3Plates group) up to a force of 120 N. The displacements of the constructs were recorded at each force increment of 10 N. ANOVA and Tukey's post-hoc tests were used for statistical analysis.</p><p><strong>Results: </strong>The 2Plates group showed higher displacement under both loading conditions (P < 0.05 for each). The same group reached displacement levels of 1 mm and 3 mm during molar loading and 1 mm, 3 mm, and 5 mm during incisal loading at lower force magnitudes relative to others (P < 0.05 for each).</p><p><strong>Conclusion: </strong>Bone-plate constructs for BMAFs stabilized with three or four standard miniplates are more likely to provide similar resistance when subjected to incisal or molar loads, in contrast to the two-miniplate configuration, which is relatively more prone to displacement.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10476427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of sitting posture with and without sole-ground contact on chewing stability and masticatory performance. 有和无足底地面接触的坐姿对咀嚼稳定性和咀嚼性能的影响。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-08-18 DOI: 10.2334/josnusd.23-0172
Kiwamu Sakaguchi, Noshir R Mehta, Tomoaki Maruyama, Leopoldo P Correa, Atsuro Yokoyama
{"title":"Effect of sitting posture with and without sole-ground contact on chewing stability and masticatory performance.","authors":"Kiwamu Sakaguchi,&nbsp;Noshir R Mehta,&nbsp;Tomoaki Maruyama,&nbsp;Leopoldo P Correa,&nbsp;Atsuro Yokoyama","doi":"10.2334/josnusd.23-0172","DOIUrl":"10.2334/josnusd.23-0172","url":null,"abstract":"<p><strong>Purpose: </strong>To verify the effect of sitting posture with and without sole-ground contact on chewing stability and masticatory performance.</p><p><strong>Methods: </strong>Thirty healthy subjects were evaluated. The Conformat was used to analyze the center of sitting pressure (COSP), and the three-dimensional motion analysis system was used to analyze changes in head and trunk postures while subjects remained in a sitting position with and without sole-ground contact. The parameters of masticatory performance and movement were calculated as follows. For evaluating masticatory performance, the amount of glucose extraction (AGE) during chewing of a gummy jelly was measured. For evaluating masticatory movements, the movement of the mandibular incisal point was recorded using the Motion Visi-Trainer V1, and parameters of the stabilities of movement path and rhythm were calculated.</p><p><strong>Results: </strong>Head and trunk sway values and the displacement of COSP were significantly smaller with sole-ground contact than those without sole-ground contact. The masticatory movement path with sole-ground contact showed less variation in the opening distance and more stable movement path compared to those without sole-ground contact. The AGE was significantly greater with sole-ground contact than that without sole-ground contact.</p><p><strong>Conclusion: </strong>Sitting posture with and without sole-ground contact affects chewing stability and masticatory performance.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10028970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of build orientation on the trueness of occlusal splints fabricated by three-dimensional printing. 构建方向对三维打印制作的咬合夹板真实性的影响。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-09-08 DOI: 10.2334/josnusd.23-0115
Andrew B Cameron, Keith Tong, Santosh Tadakamadla, Jane L Evans, Menaka Abuzar
{"title":"Effect of build orientation on the trueness of occlusal splints fabricated by three-dimensional printing.","authors":"Andrew B Cameron,&nbsp;Keith Tong,&nbsp;Santosh Tadakamadla,&nbsp;Jane L Evans,&nbsp;Menaka Abuzar","doi":"10.2334/josnusd.23-0115","DOIUrl":"10.2334/josnusd.23-0115","url":null,"abstract":"<p><strong>Purpose: </strong>Scientific evidence pertaining to the evaluation of trueness of occlusal splints fabricated using different three-dimensional (3D) printers and build orientations compared to subtractive technologies is lacking.</p><p><strong>Methods: </strong>Overall, one hundred and ten occlusal splints were manufactured using two different 3D printers and a dental mill. Five groups of ten were fabricated using the 3D printers at different build orientations (0, 30, 45, 60, and 90 degrees). In addition, a comparison group of ten occlusal splints was subtractively manufactured using a five-axis dental mill. All occlusal splints were scanned and exported as a standard tessellation language file. Analysis was conducted with metrology software with root mean square estimate average positive deviation and average negative deviation used as the measured outcome.</p><p><strong>Results: </strong>The 0 degree printing orientation was the most accurate for printer one with the root mean square value of 0.05 ± 0.01 mm, and 60 degree printing orientation was most accurate for printer two with the RMS value of 0.11 ± 0.01 mm. Subtractively manufactured occlusal splint had significantly higher trueness with the lowest RMS value of 0.03 ± 0.05 mm.</p><p><strong>Conclusion: </strong>Build orientations influence the trueness of additively manufactured occlusal splints while occlusal splints produced by subtractive manufacturing were statistically significantly more accurate.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10553806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of mandibular second molar root and canal morphology in a Black South African population using cone-beam computed tomography and two classification systems. 使用锥形束计算机断层扫描和两种分类系统对南非黑人人群下颌第二磨牙根管形态的调查。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-08-03 DOI: 10.2334/josnusd.23-0123
Glynn D Buchanan, Mohamed Y Gamieldien, Inger Fabris-Rotelli, Albert van Schoor, Andre Uys
{"title":"Investigation of mandibular second molar root and canal morphology in a Black South African population using cone-beam computed tomography and two classification systems.","authors":"Glynn D Buchanan,&nbsp;Mohamed Y Gamieldien,&nbsp;Inger Fabris-Rotelli,&nbsp;Albert van Schoor,&nbsp;Andre Uys","doi":"10.2334/josnusd.23-0123","DOIUrl":"10.2334/josnusd.23-0123","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the root and canal morphology of mandibular second molars, including anatomical variations, in a Black South African population using two classification systems.</p><p><strong>Methods: </strong>Cone-beam computed tomography images of 386 teeth were evaluated. The number of roots and canal configurations were categorized using the classifications of Vertucci (with modifications by Sert and Bayirli) and Ahmed et al. (including the modified Melton classification). Relationships between variables were assessed using Fisher's exact test (P < 0.05).</p><p><strong>Results: </strong>Mandibular second molars were predominantly two-rooted (91.7%). The majority of teeth had three canals including Type IV mesial (41.2%) and Type I (75.1%) distal (Ahmed et al. configuration: <sup>2</sup>MDM M<sup>2</sup> D<sup>1</sup>). Three or more canals were present in almost one-fifth of mesial (n = 72/386, 18.6%) and a small number of distal (n = 21/386, 5.4%) roots. Males displayed additional canals more frequently in the distal root (P = 0.02). C-shaped anatomy was found in 5.7%. Among the C-shapes, the most common was Melton's Type III in the coronal (50%), middle (81%) and apical (72%) thirds.</p><p><strong>Conclusion: </strong>In this population, mandibular second molar teeth exhibited diverse morphology, which would have clinical significance for endodontic practitioners. The Ahmed et al. classification provided a better description than the Vertucci classification.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Apically extruded debris, canal transportation, and shaping ability of nickel-titanium instruments on contracted endodontic cavities in molar teeth. 镍钛器械对磨牙收缩根管腔的顶端挤压碎片、管内运输和成形能力。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-08-03 DOI: 10.2334/josnusd.23-0050
Qinqin Zhang, Jingyi Gu, Jiadi Shen, Ming Ma, Ying Lv, Xin Wei
{"title":"Apically extruded debris, canal transportation, and shaping ability of nickel-titanium instruments on contracted endodontic cavities in molar teeth.","authors":"Qinqin Zhang,&nbsp;Jingyi Gu,&nbsp;Jiadi Shen,&nbsp;Ming Ma,&nbsp;Ying Lv,&nbsp;Xin Wei","doi":"10.2334/josnusd.23-0050","DOIUrl":"10.2334/josnusd.23-0050","url":null,"abstract":"<p><strong>Purpose: </strong>Apically extruded debris, canal transportation and shaping ability were compared between contracted endodontic cavities (CECs) and traditional endodontic cavities (TECs) after instrumentation with XP-endo Shaper (XPS), ProTaper Gold (PTG), ProTaper for hand-use (HPT) and Hero Shaper.</p><p><strong>Methods: </strong>The CECs or TECs groups were sub-divided into 24 groups according to root canal morphology and nickel-titanium (Ni-Ti) instruments. The weight of apically extruded debris was calculated using the Myers and Montgomery model. Pre- and postoperative images of teeth were scanned using micro-CT and the three-dimensional models were constructed and compared.</p><p><strong>Results: </strong>Under CECs or TECs, XPS and PTG produced less apical debris and formed less canal transportation than HPT and Hero Shaper (P < 0.05). XPS group under CECs extruded less apical debris than that under TCEs for round canals with curvature of 20°-35° (P < 0.05). The centering ratios of four tested instruments were higher under TECs than those under CECs (P < 0.05). The HPT and Hero Shaper had more transportation under CECs than that under TCEs (P < 0.05). No statistical difference was found regarding shaping ability among all the groups.</p><p><strong>Conclusion: </strong>Under CECs, XPS preserves the original root canal anatomy, meanwhile it produces less apical debris than the other instruments.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9929352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of bleaching on the color match of single-shade resin composites. 漂白对单色树脂复合材料配色的影响。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-08-03 DOI: 10.2334/josnusd.23-0159
Eleonora Forabosco, Ugo Consolo, Claudia Mazzitelli, Shaniko Kaleci, Luigi Generali, Vittorio Checchi
{"title":"Effect of bleaching on the color match of single-shade resin composites.","authors":"Eleonora Forabosco,&nbsp;Ugo Consolo,&nbsp;Claudia Mazzitelli,&nbsp;Shaniko Kaleci,&nbsp;Luigi Generali,&nbsp;Vittorio Checchi","doi":"10.2334/josnusd.23-0159","DOIUrl":"10.2334/josnusd.23-0159","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the color match of single-shade resin composites before and after bleaching procedures, through instrumental and visual analyses.</p><p><strong>Methods: </strong>Class V cavities were created on the buccal surfaces of 80 extracted human molars, restored with 4 single-shade composites (Omnichroma; Clearfil Majesty ES-2 Universal; Essentia Universal; Venus Diamond One). A spectrophotometer (VITA Easyshade V) was used to evaluate the tooth/resin color match before (T<sub>0</sub>), and 24 h (T<sub>1</sub>) and one week (T<sub>2</sub>) after dental bleaching (Opalescence Boost PF 40%). Color variations (ΔE<sub>00</sub>) were calculated and statistically analyzed (P < 0.05). Visual analysis was performed before and after tooth bleaching.</p><p><strong>Results: </strong>Spectrophotometric evaluations revealed statistically significant differences between materials at T<sub>0</sub>, T<sub>1</sub>, and T<sub>2</sub> (P < 0.05). Visual analysis reported excellent and very good grades (0 and 1, respectively), irrespective of the materials and timepoints.</p><p><strong>Conclusion: </strong>Data seem to indicate that single shade composites are able to shift their color when the surrounding tooth undergoes bleaching effects. Single-shade composites seem to achieve a good color match with the surrounding tooth structure, before and after professional bleaching.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Three-dimensional analysis for detection of pulp stones in a Saudi population using cone beam computed tomography. 使用锥束计算机断层扫描检测沙特人群牙髓结石的三维分析。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-08-24 DOI: 10.2334/josnusd.23-0091
Hassan H Kaabi, Abdullah M Riyahi, Nassr S Al-Maflehi, Saleh F Alrumayyan, Abdullah K Bakrman, Yazeed A Almutaw
{"title":"Three-dimensional analysis for detection of pulp stones in a Saudi population using cone beam computed tomography.","authors":"Hassan H Kaabi,&nbsp;Abdullah M Riyahi,&nbsp;Nassr S Al-Maflehi,&nbsp;Saleh F Alrumayyan,&nbsp;Abdullah K Bakrman,&nbsp;Yazeed A Almutaw","doi":"10.2334/josnusd.23-0091","DOIUrl":"10.2334/josnusd.23-0091","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the prevalence and distribution of pulp stones in a Saudi population.</p><p><strong>Methods: </strong>A cone beam computed tomography (CBCT) analysis of 150 upper and 150 lower dental arches was performed. The relationships between pulp stones and age, sex, tooth type, dental arch, orthodontic treatment, caries, and restoration were statistically examined (P < 0.05).</p><p><strong>Results: </strong>A total of 295 dental arches (98.3%) had at least one pulp stone, and the prevalence was higher in the maxillary teeth (56.2%) than in the mandibular teeth (48.1%) (P = 0.0003). Men were more likely to have pulp stones than women (P = 0.011 for the maxilla, P < 0.0001 for the mandible). Furthermore, age and orthodontic treatment had no significant effects on the incidence of pulp stones (P > 0.05). A higher occurrence of pulp stones was observed in the first molars (>91%), and in carious and restored teeth when compared to intact teeth (P < 0.05).</p><p><strong>Conclusion: </strong>Pulp stones were more prevalent in the upper dental arches, first molars, and carious and restored teeth, as well as in the male population, and were not associated with age or orthodontic treatment.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10061967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atomoxetine and escitalopram migrate the derangement of the temporomandibular joint morphologic and histologic changes in rats exposed to stress-induced depression. 阿托莫西汀和艾司西酞普兰迁移暴露于应激诱导的抑郁症大鼠颞下颌关节形态和组织学变化的紊乱。
IF 1.9 4区 医学
Journal of oral science Pub Date : 2023-10-01 Epub Date: 2023-07-31 DOI: 10.2334/josnusd.23-0077
Thanatta Songphaeng, Sarawut Lapmanee, Sakkarin Bhubhanil, Kamonchanok Momdee, Catleya Rojviriya, Kemporn Kitsahawong, Pattama Chailertvanitkul, Jariya U Welbat, Supawich Morkmued
{"title":"Atomoxetine and escitalopram migrate the derangement of the temporomandibular joint morphologic and histologic changes in rats exposed to stress-induced depression.","authors":"Thanatta Songphaeng,&nbsp;Sarawut Lapmanee,&nbsp;Sakkarin Bhubhanil,&nbsp;Kamonchanok Momdee,&nbsp;Catleya Rojviriya,&nbsp;Kemporn Kitsahawong,&nbsp;Pattama Chailertvanitkul,&nbsp;Jariya U Welbat,&nbsp;Supawich Morkmued","doi":"10.2334/josnusd.23-0077","DOIUrl":"10.2334/josnusd.23-0077","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this in vivo study was to determine the effects of stress-induced depression and antidepressants on depressive-like behavior, microstructure, and histomorphology of the temporomandibular joint (TMJ) using rats.</p><p><strong>Methods: </strong>Experimentally induced depression in rats was created before being treated with two antidepressants; escitalopram (selective-serotonin-reuptake inhibitors) and atomoxetine (norepinephrine-reuptake inhibitors). Micro-computed tomography (Micro-CT) was performed to measure the change in bone volume and bone porosity of the condyle. Further histological evaluation of the condylar cartilage was performed.</p><p><strong>Results: </strong>Micro-CT scanning revealed a decrease in bone volume in the depression group. The bone porosity percentage significantly increased in both the escitalopram and atomoxetine groups compared with the control group and the depression group. Histopathological analysis showed increased thickness of cartilage layers in the depression group. In the atomoxetine group, there was a significant increase in the pre-hypertrophic and hypertrophic layer thickness and cell count, but a significant decrease in proteoglycans.</p><p><strong>Conclusion: </strong>The present study findings indicated the change in TMJ characteristics, especially on the superficial part of the condylar head in the depression group. Concerning the applicability of the different antidepressants, depression with the treatment of atomoxetine has the most disadvantages due to bone porosity and cartilaginous condyle changes.</p>","PeriodicalId":16646,"journal":{"name":"Journal of oral science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9951868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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