Journal of pain and symptom management最新文献_第8页

Parallel Journeys. 平行的旅程。

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-08-05 DOI: 10.1016/j.jpainsymman.2026.07.036

Sarah Mitchell

引用次数: 0

Praying After a Miracle. 奇迹发生后的祈祷。

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-08-05 DOI: 10.1016/j.jpainsymman.2026.07.035

Brandon Oddo

引用次数: 0

Pediatric End-of-Life Care Skills Workshops: An Opportunity for Interprofessional Education. 儿科临终关怀技能研讨会：跨专业教育的机会。

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-08-04 DOI: 10.1016/j.jpainsymman.2026.07.024

Miriam C Shapiro, Alyssa R Levine, Rebecca L Freese, Stacy Remke, Anne Woll, Joseph M Miller, Susan O'Conner-Von, Kelly McManimon, Dannell Shu, Johannah M Scheurer

引用次数: 0

Sildenafil for the Management of Refractory Malignant Ischemic Pain and Edema: A Case Report. 西地那非治疗难治性恶性缺血性疼痛和水肿1例报告。

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-07-30 DOI: 10.1016/j.jpainsymman.2026.07.025

Young Chang

{"title":"Sildenafil for the Management of Refractory Malignant Ischemic Pain and Edema: A Case Report.","authors":"Young Chang","doi":"10.1016/j.jpainsymman.2026.07.025","DOIUrl":"10.1016/j.jpainsymman.2026.07.025","url":null,"abstract":"Background: Unresectable metastatic urothelial carcinoma presenting with mixed arterio-venous occlusion poses a severe therapeutic challenge, often resulting in limb-threatening ischemia and refractory pain.Case presentation: A 50-year-old Hispanic woman with stage IVB urothelial carcinoma developed severe right lower extremity ischemic pain and edema secondary to tumor encasement of the pelvic vasculature. Following progressive exacerbations, the patient suffered with refractory of pain despite aggressive escalation of opioid with adjuvant regimen, radiation therapy with systemic steroid, and lumbar epidural injection. She was successfully treated with off-label oral sildenafil.Conclusion: The targeted application of sildenafil (a phosphodiesterase type 5 inhibitor) leveraged localized hemodynamic physiology to reduce arteriolar inflow resistance and widen the arteriovenous pressure gradient. This approach achieved rapid symptom resolution and facilitated significant opioid de-escalation, highlighting the potential for precision, physiology-based palliative care in complex malignant pain syndromes.","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Hope Overrated? 希望被高估了吗？

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-07-15 DOI: 10.1016/j.jpainsymman.2026.07.007

Robert Macauley

引用次数: 0

No Morphine Please! 请不要用吗啡！

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-07-15 DOI: 10.1016/j.jpainsymman.2026.07.011

Perryn Ng

引用次数: 0

Growing the Next Generation of Hospice and Palliative Medicine Researchers. 培养下一代安宁疗护与缓和医学研究人员。

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-06-26 DOI: 10.1016/j.jpainsymman.2026.05.023

Erica C Kaye, Sarah H Cross, Rekha Thammana, Karleen Giannitrapani, Laura A Petrillo

{"title":"Growing the Next Generation of Hospice and Palliative Medicine Researchers.","authors":"Erica C Kaye, Sarah H Cross, Rekha Thammana, Karleen Giannitrapani, Laura A Petrillo","doi":"10.1016/j.jpainsymman.2026.05.023","DOIUrl":"10.1016/j.jpainsymman.2026.05.023","url":null,"abstract":"Hospice and palliative medicine (HPM) research is needed to improve care for the rapidly growing population of patients and caregivers affected by serious illness across the lifespan. Presently, multiple barriers hamper the advancement of HPM research, including limited scientific training opportunities, a relatively small pool of senior mentors, inconsistent access to institutional support, and scarce funding mechanisms to support increased numbers of early career investigators. Given this landscape, strategic investment in and guidance for the next generation of HPM researchers is critical to the success of the field. To support this mission, the Research Committee of the American Academy of Hospice and Palliative Medicine authored the following three-part article series. In this introductory article, key recent advances in HPM research funding and training opportunities are described alongside a call to action for growing the next generation of HPM investigators. The second article presents specific advice and strategies to guide early career investigators through the requisite steps to develop and sustain a career in HPM research. The final article in the series reports on the findings of a structured codesign process with experienced HPM mentors to characterize the attributes of successful HPM research mentors and codify best practices for mentorship in our field. Together, these articles provide a roadmap for building and supporting the pipeline of HPM researchers with the ultimate goal of improving care for patients and families affected by serious illness across the lifespan.","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148338937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safe Passage: Music as Therapy at the End-of-Life. 安全通道：音乐作为生命末期的治疗。

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-06-17 DOI: 10.1016/j.jpainsymman.2026.06.010

John Y Rhee

引用次数: 0

Building a Career in Hospice and Palliative Medicine Research: Advice for Early Investigators. 在临终关怀和缓和医学研究中建立职业生涯：对早期研究者的建议。

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-06-10 DOI: 10.1016/j.jpainsymman.2026.05.022

Erica C Kaye, Sarah H Cross, Lauren Hunt, Ashwin A Kotwal, Laura A Petrillo, Daniel Shalev, Rekha Thammana, Krista L Harrison

{"title":"Building a Career in Hospice and Palliative Medicine Research: Advice for Early Investigators.","authors":"Erica C Kaye, Sarah H Cross, Lauren Hunt, Ashwin A Kotwal, Laura A Petrillo, Daniel Shalev, Rekha Thammana, Krista L Harrison","doi":"10.1016/j.jpainsymman.2026.05.022","DOIUrl":"10.1016/j.jpainsymman.2026.05.022","url":null,"abstract":"Growing the next generation of hospice and palliative medicine (HPM) researchers requires creative approaches to address shortages in available mentors, resources, and funding. In response to these challenges, the American Academy of Hospice and Palliative Medicine (AAHPM) Research Committee convened a multidisciplinary working group of HPM researchers to generate practical strategies to support early career investigators (ECIs) in growing and sustaining a career focused on serious illness research. This article presents actionable advice for students, trainees, postdoctoral fellows, or early career faculty interested in HPM research, including information and encouragement to empower ECIs to pursue this career path. This paper offers specific guidance on 10 steps important to creating and sustaining a HPM research career: 1) choosing to pursue research, 2) developing mentorship relationships, 3) establishing peer mentorship and community, 4) conceptualizing and developing an initial project, 5) establishing a research identity, 6) obtaining funding and protected time, 7) bridging identities between fields, 8) anticipating challenges, 9) maintaining perspective, and 10) becoming a mentor to others. Ultimately, ECIs are the future of HPM research, and their skills and passion are needed to help grow the field and advance science to improve outcomes for patients with serious illness and their families. Endorsed by the AAHPM Research Committee, this article provides a roadmap for ECIs to grow their careers with the long-term goal of promoting compassionate, holistic care for patients, caregivers, and communities navigating serious illness.","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Flicker in the Palm: A Narrative Reflection on Guarding Life's Last Light in CAR-T Therapy. 手掌中的闪烁：在CAR-T治疗中守护生命最后的光芒的叙事反思。

IF 4 2区医学

Journal of pain and symptom management Pub Date : 2026-05-17 DOI: 10.1016/j.jpainsymman.2026.05.005

Luxiang Xu, Tingting Liu, Yao Liu

引用次数: 0