Journal of pain and symptom management最新文献

{"title":"Call to Action: Advancing Health Disparities Solutions for Seriously Ill Patients.","authors":"Vyjeyanthi S. Periyakoil MD , Kimberly Curseen MD","doi":"10.1016/j.jpainsymman.2026.01.017","DOIUrl":"10.1016/j.jpainsymman.2026.01.017","url":null,"abstract":"","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages e215-e216"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146161727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methylphenidate for Depression in Advanced Cancer: Exploratory Meta-Analysis of Randomized Trials","authors":"Bruno Almeida Costa MD ,&nbsp;Victor Almeida Costa MD ,&nbsp;Debora Oliveira MD ,&nbsp;Rodrigo Fontenele MD ,&nbsp;Henrique G.B. Coelho MD ,&nbsp;Kari Brown MD ,&nbsp;Benjamin Adegbite MD ,&nbsp;Ivan de Sousa Araújo MD, MSc ,&nbsp;Noelle Marie C. Javier MD ,&nbsp;Tammie E. Quest MD","doi":"10.1016/j.jpainsymman.2025.11.014","DOIUrl":"10.1016/j.jpainsymman.2025.11.014","url":null,"abstract":"<div><h3>Context</h3><div>Depression is prevalent and often undertreated in people living with advanced cancer. Methylphenidate (MPH) has been proposed as a faster-acting pharmacologic intervention in this setting, yet evidence remains limited.</div></div><div><h3>Objectives</h3><div>To evaluate MPH’s efficacy and safety for depression management in adults with advanced malignancies.</div></div><div><h3>Methods</h3><div>We conducted a pairwise systematic review and meta-analysis of double-blind, placebo-controlled randomized trials following Cochrane and PRISMA standards. PubMed, Embase, and CENTRAL were searched through April 04, 2025. The primary outcome was between-group change in depressive scores at 2 ± 1 weeks, expressed as standardized mean difference (SMD). Secondary outcomes included depression remission at 2 ± 1 weeks, expressed as risk ratio (RR) and risk difference (RD), and treatment-emergent adverse events (TEAEs). Random-effects models were applied.</div></div><div><h3>Results</h3><div>Three studies were included (MPH, <em>n</em> = 90; control, <em>n</em> = 99). Compared with placebo, MPH (10–45 mg/day as monotherapy or 10–20 mg/day as augmentation to conventional antidepressants) reduced depressive symptom severity (SMD, −0.81; 95%CI, −1.22 to −0.39; <em>P</em> &lt; 0.001; I² = 32%). While relative risk for depression remission narrowly missed significance (RR, 1.69; 95%CI, 0.97 to 2.96; <em>P</em> = 0.07; I² = 50%), MPH increased the absolute probability of remission (RD, 0.22; 95%CI, 0.09 to 0.34; <em>P</em> &lt; 0.001; I² = 0%; number needed to treat ≈ 5). Incidence of all analyzed TEAEs was similar between groups.</div></div><div><h3>Conclusions</h3><div>MPH may provide rapid, potentially meaningful improvement in depressive symptoms for people living with advanced cancer, while maintaining a favorable safety profile. Considering the small sample sizes and short follow-up durations across studies included in this exploratory meta-analysis, future large-scale trials are needed to confirm efficacy and define optimal candidates.</div></div>","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages e377-e386"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145604378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adding Acupuncture to Touch/Relaxation for Pain in Wartime: A Randomized Controlled Trial","authors":"Eran Ben-Arye MD ,&nbsp;Jan Vagedes MD ,&nbsp;Sameer Kassem MD, PhD, MPA ,&nbsp;Noah Samuels MD ,&nbsp;Ofer Lavie MD ,&nbsp;Vika Zaritsky BSc ,&nbsp;Orit Gressel MD","doi":"10.1016/j.jpainsymman.2025.12.001","DOIUrl":"10.1016/j.jpainsymman.2025.12.001","url":null,"abstract":"<div><h3>Context and objectives</h3><div>Patients with cancer living in war zones face significant quality of life (QoL)-related challenges. This study examined an integrative oncology (IO) intervention in northern Israel for pain and autonomic response.</div></div><div><h3>Methods</h3><div>This prospective, randomized, controlled and pragmatic study examined an IO intervention with manual-relaxation, with acupuncture (Group A) or without (Group B). ESAS (Edmonton Symptom Assessment Scale), EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer QoL Questionnaire), and MYCAW (Measure Yourself Concerns and Wellbeing) tools were used to examine QoL. Heart rate and variability (HRV) were measured at baseline and 15 minutes post-treatment, comparing frequency-domain variable changes (e.g., LN Power Total, Power HF, Power LF, Power VLF).</div></div><div><h3>Results</h3><div>Of 125 patients, Groups A (67) and B (58) had similar demographic and cancer-related characteristics. ESAS pain scores improved in both groups post-treatment (A, <em>P</em> &lt; 0.001; B, <em>P</em> = 0.002), as did anxiety, depression, and fatigue. At three weeks, Group B reported greater improvement on ESAS pain (<em>P</em> = 0.039) and MYCAW pain-related concerns (<em>P</em> = 0.025), both showing within-group improvement on EORTC pain. HRV showed greater change in Group A, with decreased LN Power Total (<em>P</em> = 0.006), LN Power LF (<em>P</em> = 0.02), and LN Power VLF (<em>P</em> = 0.026). While Relative Power HF increased marginally (<em>P</em> = 0.054), heart rate decreasing more significantly in Group B (<em>P</em> = 0.005).</div></div><div><h3>Conclusions</h3><div>IO treatments led to reduced pain among patients with cancer living in a war zone, with no additive effect of acupuncture. HRV changes suggest enhanced parasympathetic activity, with acupuncture-treated patients showing additional frequency-domain changes attributed to decreased sympathetic tone.</div></div>","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages e387-e395"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145743143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Clinicians Prenatally Discuss Management Options and Outcomes for Congenital Heart Disease","authors":"Samantha Syme BA ,&nbsp;Kelsey Schweiberger MD, MS ,&nbsp;Judy C. Chang MD, MPH ,&nbsp;Ann Kavanaugh-McHugh MD ,&nbsp;Nadine A. Kasparian PhD ,&nbsp;Robert M. Arnold MD ,&nbsp;Kelly W. Harris MD, MS","doi":"10.1016/j.jpainsymman.2025.11.026","DOIUrl":"10.1016/j.jpainsymman.2025.11.026","url":null,"abstract":"<div><h3>Context</h3><div>A prenatal diagnosis of complex congenital heart disease (cCHD) introduces significant emotional, social, and financial stress for families. Uncertainty about the future is a central source of distress for parents, particularly surrounding management options and anticipated outcomes. Little is known about how fetal cardiologists present management options, address anticipated outcomes, and offer supportive services.</div></div><div><h3>Objective</h3><div>To examine how fetal cardiology clinicians discuss management options, anticipated outcomes, and supportive services with parents following a prenatal diagnosis of complex congenital heart disease (cCHD).</div></div><div><h3>Methods</h3><div>Initial fetal cardiology consultations were audio-recorded, transcribed, and analyzed qualitatively. Deductive coding focused on management options (e.g., invasive intervention, comfort care), anticipated outcomes (e.g., quality of life, mortality risk), and supportive services (e.g., social work, peer support, palliative care).</div></div><div><h3>Results</h3><div>Five fetal cardiology clinicians from one tertiary care institution participated in 19 initial consultations. Management options discussed included invasive intervention and comfort care. Clinicians frequently described anticipated outcomes involving quality of life and mortality risk but rarely used those terms specifically. Families were most engaged during quality-of-life discussions. Palliative care as a consulting service was selectively introduced, often when the CHD diagnosis carried a higher risk of mortality. The service was frequently described as additional support.</div></div><div><h3>Conclusion</h3><div>Fetal cardiology consultations offer an important opportunity to support families navigating uncertainty following a prenatal diagnosis of CHD. Clinicians approached these conversations with empathy and a focus on long-term outcomes, though discussions about management options varied. There is an opportunity for increased presentation and integration of palliative care consultants as a longitudinal, family-centered resource, regardless of mortality risk, which may enhance supports available to families during this highly emotional period. Ongoing efforts to improve family-centered counseling and resources, such as access to perinatal palliative care, may help ensure families receive comprehensive, values-aligned information across the spectrum of care pathways.</div></div>","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages 429-436"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145634981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mean Differences and Standard Mean Difference: Important Differences in Quality of Life","authors":"Mellar P Davis MD, FCCP, FAAHPM","doi":"10.1016/j.jpainsymman.2025.11.021","DOIUrl":"10.1016/j.jpainsymman.2025.11.021","url":null,"abstract":"","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages e402-e403"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145634943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Provider Perspectives on Palliative and Complex Care Team Collaboration","authors":"Madeline L. Johnson MS ,&nbsp;Annie Friedrich PhD ,&nbsp;P. Galen DiDomizio MD","doi":"10.1016/j.jpainsymman.2025.11.015","DOIUrl":"10.1016/j.jpainsymman.2025.11.015","url":null,"abstract":"<div><h3>Context</h3><div>Pediatric palliative care and complex care programs frequently collaborate when caring for a shared population of children with medical complexity (CMC), despite programmatic heterogeneity across institutions. Yet, scant literature exists documenting the nature of collaboration between these subspecialties.</div></div><div><h3>Objectives</h3><div>The aim of the present study is to explore perceived facilitators and challenges to collaboration among pediatric complex care and palliative care providers within a subset of Midwest medical institutions.</div></div><div><h3>Methods</h3><div>Eighteen pediatric complex care and palliative care providers across ten academic medical centers completed semi-structured interviews. In addition to perceived facilitators and challenges, providers were asked to comment on hypothetical changes they would make to enhance future collaboration. Audio recordings were transcribed and qualitatively analyzed using thematic analysis.</div></div><div><h3>Results</h3><div>Qualitative analysis of provider commentary revealed individual and institution-level facilitators and challenges to collaboration between both teams, descriptions of the collaborative process when facilitators are optimized, and visions for enhancing future collaboration.</div></div><div><h3>Conclusion</h3><div>Participant responses from both subspecialties identified similar facilitators and challenges to collaboration, and supported greater integration as a means of mitigating collaborative challenges, offering ideas such as embedded programs, shared staff, or merging of divisions, among other interdisciplinary care models Future research is needed to explore methods of capturing outcomes associated with different integrative models, ideally through the incorporation of patient and family voices as a means of evaluating how clinical care is received.</div></div>","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages 373-384"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145634918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Faces of Disparity","authors":"Rebecca Kowaloff DO","doi":"10.1016/j.jpainsymman.2025.03.005","DOIUrl":"10.1016/j.jpainsymman.2025.03.005","url":null,"abstract":"","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages e297-e298"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing Pediatric Palliative Care in Vietnam: Initial Experiences and Lessons","authors":"Miranda R. Adelmann MD ,&nbsp;Huyen Thi Thanh Bui MD ,&nbsp;Mevhibe Hocaoglu PhD ,&nbsp;Quang Duy Huynh MD ,&nbsp;Quynh Thi Hoang Nguyen MD ,&nbsp;Mai Thi Tuyet Tran ,&nbsp;Tung Son Nguyen ,&nbsp;Y Quoc Y Nguyen ,&nbsp;Thuan Hoa Vuong ,&nbsp;Thơ Nguyen Minh Phan ,&nbsp;Anh Hoang Mai Nguyen MD ,&nbsp;Binh Tan Thanh Ho MD, PhD ,&nbsp;Nam Tran Nguyen MD, MSC, CKII ,&nbsp;Dinh Quang Truong MD, PhD ,&nbsp;Eric L. Krakauer MD, PhD","doi":"10.1016/j.jpainsymman.2025.10.023","DOIUrl":"10.1016/j.jpainsymman.2025.10.023","url":null,"abstract":"<div><h3>Context</h3><div>There remains an enormous unmet need for pediatric palliative care (PPC), especially in low- and middle-income countries (LMICs). Evaluation of existing PPC programs can inform development of emerging programs. In 2017, a PPC program was established at a major children’s hospital in Vietnam, a lower-middle-income country where palliative care development is at an early stage.</div></div><div><h3>Objectives</h3><div>We describe the development and operations of the first PPC program in Vietnam, and evaluate the program’s scope and early outcomes.</div></div><div><h3>Methods</h3><div>We conducted a retrospective cross-sectional study of all patients seen by the PPC inpatient consult service within an 18-month period. Descriptive statistics were used to identify trends in demographics, clinical characteristics, and end-of-life outcomes.</div></div><div><h3>Results</h3><div>Among 169 children (aged 0–15.6 years) who received PPC consultation, the most common diagnoses were cancer, traumatic injury, and congenital syndromes. Patients were referred by 14 different hospital departments. Psychosocial support was the most common PPC intervention (70%), while pain management was provided for 28% of patients. None of the patients with cancer died in the hospital.</div></div><div><h3>Conclusion</h3><div>By partnering with hospital leadership, creating opportunities for staff education, and adapting to the cultural and geographic setting, the PPC team overcame initial challenges to become a widely utilized, high-volume consult service. The PPC program may have reduced use of chemotherapy and cardiopulmonary resuscitation at end of life. The program’s strengths, challenges, and experiences may inform the development of emerging PPC programs in other LMICs.</div></div>","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages 341-350.e3"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145513100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bidirectional Associations Between End-of-Life Communication and Depressive Symptoms in Older Adults","authors":"Miharu Nakanishi RN, PhD ,&nbsp;Taeko Nakashima SW, PhD ,&nbsp;Yuki Miyamoto RN, PhD ,&nbsp;Syudo Yamasaki CPT, PhD ,&nbsp;Atsushi Nishida PSW, PhD ,&nbsp;Annicka van der Plas PhD ,&nbsp;Nienke Fleuren MD ,&nbsp;Almar Kok PhD ,&nbsp;Martijn Huisman PhD ,&nbsp;Jenny T. van der Steen MSc, PhD, FGSA","doi":"10.1016/j.jpainsymman.2025.11.029","DOIUrl":"10.1016/j.jpainsymman.2025.11.029","url":null,"abstract":"<div><h3>Context</h3><div>Advance care planning (ACP) may prepare older adults for future health problems including cognitive and physical decline. Depressive symptoms are observed among those engaging in ACP. However, the directionality of the association between ACP engagement and depressive symptoms remains uncertain.</div></div><div><h3>Objectives</h3><div>To investigate bidirectional associations between engaging in ACP and depressive symptoms in older adults at a within-person level after accounting for cognitive and physical decline.</div></div><div><h3>Methods</h3><div>A longitudinal study design using random intercept cross-lagged panel models. Community-dwelling older adults from the Longitudinal Aging Study Amsterdam (LASA) with three assessments at T0 (2015–2016), T1 (2018–2019), and T2 (2021–2022). Discussion of end-of-life wishes with a physician was used as a proxy measure for ACP engagement.</div></div><div><h3>Results</h3><div>Participants included 1669 older adults (mean [SD] age, 69.7 [7.7] years at T0; 923 [55.3%] were women). Poor cognition at T0 was associated with having discussed end-of-life wishes at T1 (β = −0.12 [95% CI, −0.23 to −0.01]), that was prospectively associated with increased depressive symptoms (0.12 [0.01 to 0.24]), decreased cognition (−0.13 [−0.22 to −0.04]), and decreased physical performance (−0.16 [−0.27 to −0.04]) at T2.</div></div><div><h3>Conclusion</h3><div>Older adults appear at risk for having depressive symptoms following discussing end-of-life wishes with their physicians. End-of-life communication may reflect an ongoing trajectory of cognitive decline which could result in further functional decline and increased depressive symptoms. A better understanding of how and which elements of end-of-life discussions are associated with the mood of older adults will provide implications for the implementation of ACP.</div></div>","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages 437-446.e6"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145701174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hospice and Palliative Medicine Fellows’ Perspectives on Physician-Assisted Dying Education","authors":"James Cescon MD ,&nbsp;Antoinette Esce MD ,&nbsp;Melanie Koren MD ,&nbsp;Edith Meyerson DMin, BCC ,&nbsp;Mollie A. Biewald MD ,&nbsp;Robert M. Arnold MD ,&nbsp;Anup Bharani MD ,&nbsp;Laura Belland MD","doi":"10.1016/j.jpainsymman.2025.11.013","DOIUrl":"10.1016/j.jpainsymman.2025.11.013","url":null,"abstract":"<div><h3>Context</h3><div>Physician-assisted dying (PAD) is legal in a growing number of U.S. states, with access expanding nationally due to recent legislative changes. Despite this, how to address PAD in hospice and palliative medicine (HPM) fellowship programs remains undefined. The perspectives of HPM fellows regarding PAD education have not been studied.</div></div><div><h3>Objectives</h3><div>To assess HPM fellows’ experiences and interest in a formal PAD curriculum, including preferred content areas and anticipated relevance to future practice.</div></div><div><h3>Methods</h3><div>An anonymous nine-item survey was sent to all HPM fellows (<em>N</em> = 21) at the Icahn School of Medicine at Mount Sinai. Survey domains included prior exposure to PAD, attitudes toward PAD education, and intention to provide PAD in future clinical practice.</div></div><div><h3>Results</h3><div>The response rate was 100%. Most fellows (81%) had no formal education on PAD. All respondents agreed that learning about PAD in fellowship is important. Topics of interest included ethical considerations (95%), legal criteria (86%), responding to requests in serious illness conversations (86%), navigating requests (76%), and pharmacology/modes of ingestion (71%). A majority (62%) were interested in an away elective with a PAD provider. While only 10% intended to provide PAD in future practice, 57% were unsure or had not thought about it, and 33% were not considering it.</div></div><div><h3>Conclusion</h3><div>Fellows unanimously supported including PAD education in HPM training, regardless of intent to participate in the practice. These findings underscore a clear educational need and may guide curriculum development. To our knowledge, this is the first survey assessing HPM fellows’ views on PAD.</div></div>","PeriodicalId":16634,"journal":{"name":"Journal of pain and symptom management","volume":"71 3","pages":"Pages e372-e376"},"PeriodicalIF":3.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145604274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}