Journal of Obesity最新文献

{"title":"Anthropometric Measurements and Correlations to Glucometabolic and Cardiovascular Risk in Obese Patients Undergoing Gastric Bypass Surgery.","authors":"Erica Aldenbäck,&nbsp;Hans-Erik Johansson","doi":"10.1155/2021/6647328","DOIUrl":"https://doi.org/10.1155/2021/6647328","url":null,"abstract":"<p><p>Abdominal obesity is associated with hypertension, increased fasting glucose, HbA1c, and cholesterol. Body mass index (BMI) is frequently used to measure and define obesity and as inclusion criteria for bariatric surgery. Sagittal abdominal diameter (SAD) has been suggested to predict the amount of visceral fat, metabolic traits, and cardiometabolic risk superior to BMI. The aim was to test whether SAD has stronger correlations to glucometabolic traits compared to BMI. One hundred and fifty-five (108 women, 47 men) morbidly obese patients undergoing bariatric surgery were evaluated before (baseline), 6 and 12 months after Roux-en-Y gastric bypass (RYGBP). BMI was reduced from 43.7 kg/m2 (baseline) to 31.3 kg/m2 (12 months) and SAD from 32.6 to 23.2 cm (both <i>p</i><0.001). SAD correlated with CRP (<i>p</i>=0.04), fasting glucose (<i>p</i>=0.008), HbA1c (<i>p</i>=0.016), triglycerides (<i>p</i>=0.017), systolic blood pressure (<i>p</i>=0.032), and vitamin D (<i>p</i>=0.027). BMI correlated with CRP (<i>p</i>=0.006), triglycerides (<i>p</i>=0.016), vitamin D (<i>p</i>=0.002), and magnesium (<i>p</i>=0.037). Despite RYGBP surgery, vitamin D was significantly increased. Liver enzymes were significantly lowered after RYGBP and the change over time in SAD correlated with gamma-glutamyltransferase. SAD was superior to BMI to predict glucose disturbance and dyslipidemia implying increased use of SAD as it is cost effective and simple to perform in the clinic and could be of value when considering patients for bariatric surgery.</p>","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":"2021 ","pages":"6647328"},"PeriodicalIF":3.3,"publicationDate":"2021-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39265510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural Brain Changes Associated with Overweight and Obesity.","authors":"Erick Gómez-Apo,&nbsp;Alejandra Mondragón-Maya,&nbsp;Martina Ferrari-Díaz,&nbsp;Juan Silva-Pereyra","doi":"10.1155/2021/6613385","DOIUrl":"https://doi.org/10.1155/2021/6613385","url":null,"abstract":"Obesity is a global health problem with a broad set of comorbidities, such as malnutrition, metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. This review describes recent findings of neuroimaging and two studies of cell density regarding the roles of overnutrition-induced hypothalamic inflammation in neurodegeneration. These studies provided consistent evidence of smaller cortical thickness or reduction in the gray matter volume in people with overweight and obesity; however, the investigated brain regions varied across the studies. In general, bilateral frontal and temporal areas, basal nuclei, and cerebellum are more commonly involved. Mechanisms of volume reduction are unknown, and neuroinflammation caused by obesity is likely to induce neuronal loss. Adipocytes, macrophages of the adipose tissue, and gut dysbiosis in overweight and obese individuals result in the secretion of the cytokines and chemokines that cross the blood-brain barrier and may stimulate microglia, which in turn also release proinflammatory cytokines. This leads to chronic low-grade neuroinflammation and may be an important factor for apoptotic signaling and neuronal death. Additionally, significant microangiopathy observed in rat models may be another important mechanism of induction of apoptosis. Neuroinflammation in neurodegenerative diseases (such as Alzheimer's and Parkinson's diseases) may be similar to that in metabolic diseases induced by malnutrition. Poor cognitive performance, mainly in executive functions, in individuals with obesity is also discussed. This review highlights the neuroinflammatory and neurodegenerative mechanisms linked to obesity and emphasizes the importance of developing effective prevention and treatment intervention strategies for overweight and obese individuals.","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":" ","pages":"6613385"},"PeriodicalIF":3.3,"publicationDate":"2021-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39265507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adulteration of the Herbal Weight Loss Products by the Illegal Addition of Synthetic Antiobesity Medications: A Pilot Study.","authors":"Farzin Firozian,&nbsp;Amir Nili-Ahmadabadi,&nbsp;Shirin Moradkhani,&nbsp;Miad Moulaei,&nbsp;Zohreh Fasihi,&nbsp;Davoud Ahmadimoghaddam","doi":"10.1155/2021/9968730","DOIUrl":"10.1155/2021/9968730","url":null,"abstract":"<p><strong>Background: </strong>Some anorexic agents are used to fraudulent augmentation herbal weight loss formulations. This study was designed to evaluate the potential existence of illicit substances in 63 herbal weight loss formulations collected from local apothecaries in Hamadan, Iran.</p><p><strong>Methods: </strong>The thin-layer chromatography method was applied for the primary screening of potential illicit substances in the samples. The positive samples were analyzed using an isocratic high-performance liquid chromatography method.</p><p><strong>Results: </strong>The results showed that 26.98% of the samples contained 17.76 ± 6.02 mg/cap of sibutramine. Daily therapeutic dose intake of sibutramine is in the range of 5 to 15 mg daily.</p><p><strong>Conclusion: </strong>Since apothecaries have advised consumers to take at least two capsules a day, it seems that the blood concentration of sibutramine will likely rise beyond the therapeutic concentration and become toxic. Therefore, the usage of such products could pose serious risks to consumers' health.</p>","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":"2021 ","pages":"9968730"},"PeriodicalIF":3.3,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10224262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Body Appreciation and Self-Esteem and Associated Factors among Omani University Students: An Online Cross-Sectional Survey.","authors":"Atika Khalaf,&nbsp;Iman Al Hashmi,&nbsp;Omar Al Omari","doi":"10.1155/2021/5523184","DOIUrl":"https://doi.org/10.1155/2021/5523184","url":null,"abstract":"<p><strong>Background: </strong>Given the rapid pace of globalization and the fact that the Sultanate of Oman is experiencing a significant impact of social media on specifying appearance norms among youth in the country, research into positive body images and self-esteem among young individuals has become a national priority. Whilst body image has been well studied across cultures, both positive body image and the relationship between positive body image and self-esteem among Omani youth have been neglected. The aim of the study was to investigate the relationship between positive body image and self-esteem and associated sociodemographic factors among Omani university students based on gender.</p><p><strong>Methods: </strong>This cross-sectional study used an online survey consisting of the two questionnaires that are Body Appreciation Scale-2 and Rosenberg's Self-Esteem Scale. A total of 237 students were recruited from Sultan Qaboos University's different colleges.</p><p><strong>Results: </strong>The results indicated that positive body image has a significant relationship with an individual's self-esteem (<i>β</i> = 0.122, <i>t</i> = 2.197, <i>p</i>=0.038), Cumulative Grade Point Average (cGPA) (<i>β</i> = 0.140, <i>t</i> = 2.306, <i>p</i>=0.022), body mass index (BMI) (<i>β</i> = -0.414, <i>t</i> = -6.930, <i>p</i> < 0.001), monthly household income (<i>β</i> = -0.129, <i>t</i> = 2.467, <i>p</i>=0.029), and the number of social media accounts (≥2, <i>β</i> = -0.132, <i>t</i> = -2.232, <i>p</i>=0.027). In addition, an individual's self-esteem was significantly associated with an individual's cGPA (<i>β</i> = 0.231, <i>t</i> = 3.592, <i>p</i> < 0.001) and mothers' educational level (<i>β</i> = -0.130, <i>t</i> = -2.065, <i>p</i>=0.040) besides body appreciation (<i>β</i> = 0.160, <i>t</i> = 2.491, <i>p</i>=0.013).</p><p><strong>Conclusions: </strong>The findings of this study shed light on the current status of positive body image among university students of Oman. In light of the new knowledge, we propose health interventions that include strategies such as involvement of family, to maintain and/or promote positive body image perceptions among young individuals and subsequently promote healthy appreciation of the physical appearance and self-esteem.</p>","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":"2021 ","pages":"5523184"},"PeriodicalIF":3.3,"publicationDate":"2021-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39181414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concomitant versus Delayed Cholecystectomy in Bariatric Surgery.","authors":"Hatem Elgohary,&nbsp;Mahmoud El Azawy,&nbsp;Mohey Elbanna,&nbsp;Hossam Elhossainy,&nbsp;Wael Omar","doi":"10.1155/2021/9957834","DOIUrl":"https://doi.org/10.1155/2021/9957834","url":null,"abstract":"<p><strong>Background: </strong>Obesity and weight loss after bariatric surgery have a close association with gallbladder disease. The performance and proper timing of laparoscopic cholecystectomy (LC) with bariatric surgery remain a clinical question.</p><p><strong>Objective: </strong>Evaluation of the outcome of LC during bariatric surgery whether done concomitantly or delayed according to the level of intraoperative difficulty.</p><p><strong>Methods: </strong>The prospective study included patients with morbid obesity between December 2018 and December 2019 with preoperatively detected gallbladder stones. According to the level of difficulty, patients were allocated into 2 groups: group 1 included patients who underwent concomitant LC during bariatric surgery, and group 2 included patients who underwent delayed LC after 2 months. In group 1, patients were further divided into subgroups: LC either at the beginning (subgroup A) or after bariatric surgery (subgroup B).</p><p><strong>Results: </strong>Operative time in group 1 vs. 2 was 92.63 ± 28.25 vs. 68.33 ± 17.49 (<i>p</i> < 0.001), and in subgroup A vs. B, it was 84.19 ± 19.62 vs. 130.0 ± 31.62 (<i>p</i> < 0.001). One patient in each group (2.6% and 8.3%) had obstructive jaundice, <i>p</i> > 0.001. In group 2, 33% of asymptomatic patients became symptomatic for biliary colic <i>p</i> > 0.001. LC difficulty score was 2.11 ± 0.70 vs. 5.66 ± 0.98 in groups 1 and 2, respectively, <i>p</i> < 0.001. LC difficulty score decreased in group 2 from 5.66 ± 0.98 to 2.26 ± 0.78 after 2 months of bariatric surgery, <i>p</i> < 0.001.</p><p><strong>Conclusion: </strong>Timing for LC during bariatric surgery is challenging and should be optimized for each patient as scheduling difficult LC to be performed after 2 months may be an option.</p>","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":"2021 ","pages":"9957834"},"PeriodicalIF":3.3,"publicationDate":"2021-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39162945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipid Accumulation Product Is More Related to Insulin Resistance than the Visceral Adiposity Index in the Maracaibo City Population, Venezuela.","authors":"Valmore Bermúdez, Juan Salazar, Jorge Fuenmayor, Manuel Nava, Ángel Ortega, Pablo Duran, Milagros Rojas, Roberto Añez, Alejandra Rivas-Montenegro, Lissé Angarita, Maricarmen Chacín, Clímaco Cano, Manuel Velasco, Joselyn Rojas","doi":"10.1155/2021/5514901","DOIUrl":"10.1155/2021/5514901","url":null,"abstract":"<p><strong>Background: </strong>Visceral adiposity is related to insulin resistance (IR), a metabolic state considered as a risk factor for other cardiometabolic diseases. In that matter, mathematical indexes such as the visceral adiposity index (VAI) and the lipid accumulation product (LAP) could indirectly assess IR based on visceral adiposity.</p><p><strong>Objective: </strong>To evaluate the association and diagnostic accuracy of VAI and LAP to diagnose IR in the adult population of Maracaibo city.</p><p><strong>Methods: </strong>This is a cross-sectional descriptive study with multistage sampling. Receiver operating characteristic (ROC) curves were built to determine VAI and LAP cutoff points to predict IR. A set of logistic regression models was constructed according to sociodemographic, psychobiologic, and metabolic variables.</p><p><strong>Results: </strong>1818 subjects were evaluated (51.4% women). The area under the curve (AUC) values for LAP and VAI were 0.689 (0.665-0.714) and 0.645 (0.619-0.670), respectively. Both indexes showed a higher IR risk in the upper tertile in bivariate analysis. However, in the logistic regression analysis for the IR risk, only the 2nd (OR: 1.91; 95% CI: 1.37-2.65; <i>p</i> < 0.01) and 3rd (OR: 5.40; 95% CI: 3.48-8.39; <i>p</i> < 0.01) LAP tertiles showed a significant increase. This behaviour was also observed after adjusting for hs-C-reactive protein (hs-CPR).</p><p><strong>Conclusion: </strong>Although both indexes show a low predictive capacity in individuals with IR in the Maracaibo city population, the LAP index was more strongly associated with IR.</p>","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":"2021 ","pages":"5514901"},"PeriodicalIF":3.3,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39126711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual Health Determinants of Normal Weight, Overweight, and Obese Sexual Minority Men.","authors":"Henrique Pereira","doi":"10.1155/2021/1272316","DOIUrl":"10.1155/2021/1272316","url":null,"abstract":"<p><strong>Background: </strong>With the growing recognition of overweight and obesity as significant, international public health concerns, the body of research investigating the relationship between body mass index (BMI), sexual health, and sexual functioning in sexual minority men is still scarce.</p><p><strong>Objective: </strong>The purpose of this study is to assess sexual health determinants (sexual behavior and sexual functioning) in relation to normal weight, overweight, and obesity among gay and bisexual men.</p><p><strong>Methods and materials: </strong>The survey included four categories of questions/measurements, encompassing sociodemographic information, protected/unprotected sexual behaviors, sexual functioning, and BMI. The survey was conducted online, and recruitment consisted of online notifications (emails and electronic messages) and advertisements sent to LGBT community organizations, mailing lists, and social networks.</p><p><strong>Results: </strong>The study sample was composed of 741 gay and bisexual men, ranging in age from 21 to 75 years (<i>M</i> _age = 43.30, SD_age = 11.37); 62.5% of men self-identified as gay and 37.5% as bisexual. Prevalence of normal weight was 50.3%, of overweight, 33.3%, and of obesity, 16.4%. Participants with overweight and obesity showed a lower frequency of anal receptive sex without condoms when scompared to participants with normal weight. Hierarchical multiple regression analysis to assess the effects of BMI on sexual health showed that being younger in age, self-identifying as gay, being in a relationship, having longer penises, adopting insertive position in sex, and being normal weight were significant predictors of anal receptive sex without condoms, explaining 24.2% of the total variance. Yet, BMI was not predictive of sexual functioning.</p><p><strong>Conclusion: </strong>These findings highlight the importance of including BMI in sexual behavior models of sexual minority men to better understand BMI's role in influencing sexual risk.</p>","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":"2021 ","pages":"1272316"},"PeriodicalIF":3.3,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25558798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chinese Herbal Medicine for Weight Management: A Systematic Review and Meta-Analyses of Randomised Controlled Trials.","authors":"Ann Rann Wong,&nbsp;Angela Wei Hong Yang,&nbsp;Kangxiao Li,&nbsp;Harsharn Gill,&nbsp;Mingdi Li,&nbsp;George Binh Lenon","doi":"10.1155/2021/3250723","DOIUrl":"https://doi.org/10.1155/2021/3250723","url":null,"abstract":"<p><strong>Objective: </strong>This review investigated the effects and safety of Chinese herbal medicine (CHM) formulas on weight management.</p><p><strong>Methods: </strong>Eighteen databases in English, Chinese, Korean, and Japanese were searched from their inceptions to September 2019. The treatment groups included CHM formulations, and the control included placebo, Western medication (WM), and lifestyle intervention (LI), with or without cointerventions (WM and/or LI). Quality of studies was assessed using Cochrane Collaboration's risk of bias assessment tool. Body weight and body mass index (BMI) were analysed in RevMan v5.4.1 and expressed as mean differences with 95% confidence intervals (CI), while adverse events were expressed as risk ratio with 95% CI.</p><p><strong>Results: </strong>Thirty-nine RCTs were eligible for qualitative analysis, 34 of which were included in the meta-analyses. The majority of studies had a high or unclear risk of selection, performance, and detection bias. Twenty-five CHM studies involving cointerventions revealed that CHM had significant adjunct effects on body weight and BMI at the end of treatment compared to control. No serious adverse events were reported in the CHM groups.</p><p><strong>Conclusion: </strong>CHM indicates a promising adjunct to facilitate WM or lifestyle change for weight management. However, methodological barriers such as lack of allocation concealment and double-blinding may have led to challenges in data synthesis. More rigorously designed RCTs involving cointerventions are warranted.</p>","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":" ","pages":"3250723"},"PeriodicalIF":3.3,"publicationDate":"2021-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7964117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25513676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wearable Activity Tracking Device Use in an Adolescent Weight Management Clinic: A Randomized Controlled Pilot Trial.","authors":"Kanika Bowen-Jallow,&nbsp;Omar Nunez-Lopez,&nbsp;Alex Wright,&nbsp;Erika Fuchs,&nbsp;Mollie Ahn,&nbsp;Elizabeth Lyons,&nbsp;Daniel Jupiter,&nbsp;Lindsey Berry,&nbsp;Oscar Suman,&nbsp;Ravi S Radhakrishnan,&nbsp;Andrea M Glaser,&nbsp;Deborah I Thompson","doi":"10.1155/2021/7625034","DOIUrl":"https://doi.org/10.1155/2021/7625034","url":null,"abstract":"<p><strong>Background: </strong>The use of physical activity tracker devices has increased within the general population. However, there is limited medical literature studying the efficacy of such devices in adolescents with obesity. In this study, we explored the feasibility of using wearable activity tracking devices as an adjunct intervention on adolescents with obesity.</p><p><strong>Methods: </strong>Randomized controlled pilot trial evaluated the feasibility (attrition ≤50%) of an activity tracking intervention (ATI) and its effects on weight loss in adolescents with obesity enrolled in an adolescent weight management clinic (AWMC). Outcomes included feasibility (attrition rate) and absolute change in BMI. Differences between groups at 6, 12, and 18 weeks were examined.</p><p><strong>Results: </strong>Forty-eight participants were enrolled in the study. Eighteen subjects were randomly assigned to the ATI group and 30 to control. The average age was 14.5 years. Overall, the majority of participants were Hispanic (56%). Sexes were equally distributed. The average baseline BMI was 37.5 kg/m². At the study conclusion, the overall attrition rate was 52.1%, 44.4% in the ATI group versus 56.6% in the control group, with a differential attrition of 12.2%. The ATI and control groups each showed an absolute decrease in BMI of -0.25 and -2.77, respectively, with no significant differences between the groups.</p><p><strong>Conclusion: </strong>The attrition rate in our study was >50%. Participation in the AWMC by the ATI and control groups resulted in maintenance of BMI and body weight for the study duration. However, the use of an activity tracking device was not associated with greater weight loss. This trial is registered with NCT03004378.</p>","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":" ","pages":"7625034"},"PeriodicalIF":3.3,"publicationDate":"2021-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38868321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reference Value for the Distance Walked in the Six-Minute Walk Test in Obese Brazilian Men in the Preoperative Period of Bariatric Surgery.","authors":"Cesar Antonio Luchesa,&nbsp;Thiago Thomaz Mafort,&nbsp;Rafael Rodrigues da Silva,&nbsp;Isabela Cristina Paro,&nbsp;Fernanda Micheli de Souza,&nbsp;Agnaldo José Lopes","doi":"10.1155/2021/9577412","DOIUrl":"https://doi.org/10.1155/2021/9577412","url":null,"abstract":"<p><strong>Background: </strong>Obesity has several effects on the mechanics of the rib cage that may impair the exercise performance of obese individuals and therefore impact the assessment of surgical risk. This study aimed to establish a reference value for the 6-minute walk distance (6 MWD) in obese Brazilian men in the preoperative period of bariatric surgery that considers the effect of lung function.</p><p><strong>Methods: </strong>This was a cross-sectional study in which 104 obese men underwent the six-minute walk test (6 MWT) before bariatric surgery. They also underwent the spirometry test and respiratory muscle strength measurement before the 6 MWT.</p><p><strong>Results: </strong>The 6 MWD was correlated with age (<i>r</i> = -0.388, <i>p</i>=0.0005), weight (<i>r</i> = -0.365, <i>p</i>=0.0007), height (<i>r</i> = 0.285, <i>p</i>=0.022), body mass index (BMI) (<i>r</i> = -0.543, <i>p</i> < 0.0001), forced vital capacity (FVC) (<i>r</i> = 0.472, <i>p</i> < 0.0001), peak expiratory flow (<i>r</i> = 0.253, <i>p</i>=0.031), and maximal inspiratory pressure (<i>r</i> = 0.313, <i>p</i>=0.017). In the stepwise forward regression analysis, BMI, FVC, and age were the only variables that independently predicted the 6 MWD and explained 40% of its variability. The reference equation proposed for obese Brazilian men is 6 MWD (<i>m</i>) = 570.5 - (3.984 × BMI_kg/m2) + (1.093 × FVC_%predicted) - (0.836 × age_yrs).</p><p><strong>Conclusion: </strong>In this sample of obese Brazilian men, lung function contributed to poor performance in the 6 MWT. In these individuals, BMI, FVC, and age were the variables that composed the reference equation for the 6 MWD. Thus, in several clinical settings, such as in the evaluation before bariatric surgery, pulmonary function data are important to determine the reference value for the 6 MWD.</p>","PeriodicalId":16628,"journal":{"name":"Journal of Obesity","volume":"2021 ","pages":"9577412"},"PeriodicalIF":3.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9865976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}