Damanhour Journal of Veterinary Sciences最新文献

{"title":"Corn Silk Extract attenuates Acetaminophen-induced Hepatotoxicity in Rats","authors":"Enas Wans, Mohamed M. Ahmed, A. Mousa, Enas Tahoon, S. Orabi","doi":"10.5455/DJVS.2020.30024.1015","DOIUrl":"https://doi.org/10.5455/DJVS.2020.30024.1015","url":null,"abstract":"Paracetamol (acetaminophen-N-acetyl-p-aminophenol, PCM), a most common antipyretic & analgesic compound is widely used for the treatment of cold, cough, fever, pain including chronic pain, muscular ache, migraine, menstrual cramps, headache, backache and toothache. Acetaminophen over dosage is considered as one of the major causes of hepatic toxicity. The current study aimed to investigate the protective effect of corn silk methanolic extract (CSME) against acetaminophen (APAP)-induced hepatic toxicity. Therefore, the present study was carried out on 40 male Wistar albino rats, which were randomly allocated into four groups (n=10). Control group; orally administered with 0.9% normal saline. CSME group, orally received CSME, 400 mg/kg BW daily for 5 weeks; APAP group , orally administered with a single dose of APAP, 2g/kg BW; APAP+ CSME group , orally administered with CSME as in CSME group, followed by a single oral dose of APAP as in APAP group. The results of this study revealed that APAP caused a significant elevation in alanine  transaminase (ALT) and aspartate transaminase (AST) activities. Also, APAP caused significant increases in of  malondialdehyde (MDA) and nitric oxide (NO) concentrations compared with control group. However, pre-treatment with CSME restored all biochemical parameters toward the normal levels as the control group. In conclusion, oral administration of CSME protected rats against APAP hepatic toxicity through its antioxidant protective mechanisms.","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121219894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cinnamon Extract Ameliorates Liver Damage And Oxidative Stress Induced By Paracetamol In Male Rats","authors":"Hosny Abd El Fadil, A. Moustafa, H. Khalifa, A. Hossam, Amany Behairy","doi":"10.5455/DJVS.2020.25744.1011","DOIUrl":"https://doi.org/10.5455/DJVS.2020.25744.1011","url":null,"abstract":"Paracetamol is a harmless antipyretic and analgesic at the therapeutic dose, but when used by overdose cause hepatic damage. The study was planned to evaluate the effect of cinnamon extract on paracetamol-induced liver injury in rats. Thirty male rats were allocated into six equal groups, control group, silymarin group cinnamon group, paracetamol group, cinnamon + paracetamol group and silymarin + paracetamol group. At the end of experiment, blood and liver tissue samples were collected. Paracetamol caused rise in liver enzymes including alanine amino transaminase (ALT), aspartate amino transaminase (AST) and alkaline phosphatase (ALP), with changes in protein and lipid profiles. It also caused hepatic lipid peroxidation with decreasing the activities of antioxidant enzymes catalase (CAT) and superoxide dismutase (SOD). Pretreatment with cinnamon extract for 30 days improves the adverse effects of paracetamol evidenced by biochemical and histopathological findings. In conclusion, cinnamon extract can serve as a hepatoprotective agent against paracetamol-induced liver damage.","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126424142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Dietary Biogen® Supplementation with Water Treatment with Q Z Toss™ on Nile Tilapia.","authors":"M. Thabet, A. Gaafar, M. Tanekhy, A. Alsenosy, Abdalla Elbialy, Samar S. Abaza, M. Soliman","doi":"10.5455/DJVS.2020.23733.1010","DOIUrl":"https://doi.org/10.5455/DJVS.2020.23733.1010","url":null,"abstract":"The current study was designed to investigate the probiotic potential of the BiogenO with and without the water quality improvement product (Q Z Toss™) on growth and health performance of Nile tilapia (Oreochromis niloticus). Four fish groups were maintained on control diet supplemented with the BiogenO for one month with or without inclusion of Q Z Toss™ in water. Dietary levels of BiogenO exhibited significant raise in growth parameters with no harmful impacts on hepatic functions. Importantly, Q Z Toss™ supplemented group showed obvious decline of water ammonia level. However, water ammonia level didn’t change in BiogenO treated fish compared to control. The histopathological examination revealed better hepatopancreas and intestinal epithelial status in BiogenO treated groups than other groups. Therefore, we can recommend the dietary addition of BiogenO in aqua-feed along with Q Z Toss™ application in rearing water as a proficient method to achieve feasible and sustainable fish health.","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125706525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical alterations in serum biomarkers of Nile tilapia Oreochromis Niloticus exposed to sodium fluoride and Moringa oleifer","authors":"Nirmen Mekky, K. Sadek, M. Soliman, R. Khalil","doi":"10.5455/DJVS.2020.23855.1009","DOIUrl":"https://doi.org/10.5455/DJVS.2020.23855.1009","url":null,"abstract":"Fish are extremely sensitive to many water-borne toxicants, due to theirprolonged, constant and direct contact with the aquatic environment where chemical exposure occurs over the entire body surface and ecological significance in any natural systems. This study investigated the effects of sodium fluoride on O. niloticus tissues and protection effect of Moringa oleifera to these tissues by exposed of O. niloticus to 1/10 dose of sodium fluoride 96hr-LC50 (6.1 mg/L) and study the changes in serum biomarkers of liver and kidney functions, total antioxidant capacity (TAC) and lipid peroxidation (LPO). Two hundred and sixty O. niloticus were used for determination of LC50 and chronic toxicity the fish divided into four groups of fifty fishes each. Control group, received no any treatment; 1/10 dose of sodium fluoride LC50 (6.1 mg/L), sodium fluoride plus Moringa oleifera powder and Moringa oleifera 1% of diet. The results showed that, sodium fluoride at dose of 6.1 mg/L significantly decreased serum total protein, albumin, globulin and TAC of O. niloticus. The ALT and AST activities and LPO contents of sodium fluoride exposed group was found higher than the M. oleifera supplemented groups.  On the basis of present findings it could be concluded that increased sodium fluoride content in water causes adverse effect on fish blood biochemistry. The changes of plasma biomarkers were the physiological responses of O. niloticus to the stress of sodium fluoride exposure. Moringa oleifera can be grown to produce more natural products and materials against heavy metals toxicity in aquatic ecosystem.","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132912396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Susceptibility of Japanese Quail and Chickens to Infection with Newcastle disease Virus Genotype VIId","authors":"Al-Shaimaa E. Abd El Aziem, H. Abd-Ellatieff, A. Elbestawy, Soaad Belih, H. S. A. El-Hamid, A. Abou-Rawash","doi":"10.5455/DJVS.2020.27706.1013","DOIUrl":"https://doi.org/10.5455/DJVS.2020.27706.1013","url":null,"abstract":"The susceptibility of Japanese quail to infection with Newcastle disease (ND) virus, was evaluated throughout experimental study. A total of 25quails (36 days old) and 25 chickens (28 day old) were divided into 4 groups. G1 (non-vaccinated, non-challenged quail), G2 (non-vaccinated challenged quail by genotype VIId), G3 (non-vaccinated, non-challenged chickens), and G4 (non-vaccinated challenged chickens by genotype VIId). Hemagglutination inhibition (HI) assay for NDV was conducted pre and post-challenge. Clinical signs, gross and histopathological examinations were performed and lesions were recorded. NDV genotypeVIId (NDV-VIId) results in 33% mortality in quails to 100% mortality in chickens. From that study, we found that quails are resist to NDV-VIId infection, however this virus is a highly virulent velogenic NDV strain according to intracerebral pathogenicity index test (ICPT), and causing highly contagious disease in poultry. ND resulted in respiratory and nervous signs in chickens and quails with a higher severity of lesions scores in chickens. Non suppurative encephalitis, trachitis pneumonia and enteritis were the main histopathological features that were recorded in infected birds.","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132314103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ovine fascioliasis: environmental epidemiology and meta-analysis of the prevalence, Agro-ecological and economic factors in five provinces of the Nile Delta region of Egypt","authors":"S. Al-Hakeem, M. Omar","doi":"10.5455/DJVS.2020.67811","DOIUrl":"https://doi.org/10.5455/DJVS.2020.67811","url":null,"abstract":"This study is aimed to determine the prevalence of ovine fascioliasis and to evaluate the impact of putative risk factors in five provinces located in the Nile Delta region of Egypt. A cross-sectional method was conducted from 2014 to 2015 involving the coprological investigation using sedimentation technique and questionnaire survey in Beheira, Kafr-Sheikh, sharkia, Menofia and Gharbia province. A total of 4920 sheep (n= 80 flocks) was sampled in order to achieve a representative sample of 140 flocks. The dataset was analyzed using comparative meta-analysis, the pooled prevalence was 17.87%, and the higher prevalence was recorded in the Baladi breed 21.86% with 95% confidence interval followed by the Barki 18.12% (95% CI-0.58, 1.42) and the Rahmani 13.58% (95% CI-0.19, 0.25). Sixteen parameters of population and agro-ecological factors were considered for assessing the heterogeneity analysis of age, sex, breeds, body condition scores, flock sizes, and ecological conditions. Low prevalence of fascioliasis was observed in summer, spring, and autumn. Sheep flock sizes ranging from 100-150 and over 150 were associated with a higher prevalence of Fasciola than flock size less than 100 sheep. The prevalence was higher in relative humidity ranging from 50 to 60 and over 60, compared to conditions of relative humidity <50. The total weight of infected sheep with fascioliasis was significantly lower (44.17 kg) than healthy sheep (55.29 kg). The monetary value of weight reduction for the infected sheep estimated was 301.55 Egyptian pounds (EGP). Additionally, the average treatment cost/sheep was 46.22 EGP, and the cost of mortality for three-dead sheep was 4800 EGP. The study findings revealed that urgent strategic control measures are required based on attributing risk factors of fascioliasis in the Nile Delta regions of Egypt. Furthermore, epidemiological information about the disease and associated risk factors may aid in developing effective control measures and strategic anthelminthic intervention against fascioliasis and improving the productivity of the sheep industry in Egypt.","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121314942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strain variation to cold stress in growth performance, carcass traits, hematological, blood biochemical parameters and antioxidant enzymes in broilers","authors":"Mahmoud M. Aboghanima","doi":"10.21608/djvs.2019.19406.1006","DOIUrl":"https://doi.org/10.21608/djvs.2019.19406.1006","url":null,"abstract":"","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131764338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of two dietary prebiotic oligosaccharides supplementation on productive performance and carcass traits with special attention to their biochemical alterations in two rabbit breeds","authors":"A. A. El-Aziz, Mahmoud M. Aboghanima, Sherif Kamel, Eman M. El-Deeb, U. Mahrous","doi":"10.5455/DJVS.2019.19337.1005","DOIUrl":"https://doi.org/10.5455/DJVS.2019.19337.1005","url":null,"abstract":"One-hundred and twenty weaned male rabbits (New Zealand White and APRI) of 45 days of age and 737±17 g body weight were alloرtted randomly into six groups (20 rabbits each) in factorial arrangement to investigate the effects of dietary supplementation of two prebiotic oligosaccharides (Mannan-oligosaccharides and Isomalto-oligosaccharides) on their growth performance and carcass traits. The results of the present work showed that dietary supplementation of prebiotic oligosaccharides, in particular Mannan-oligosaccharides (MOS) and Isomalto-oligosaccharides (IMO) significantly accelerated body weight gain (BWG) in rabbits, and reduced feed conversion ratio (FCR). There are some differences in growth performance traits due to breed effect. The interaction between prebiotics supplementation and breed was significant on BWG and FCR. supplementation of (IMO) revealed significant differences in most of studied carcass traits, except in forequarter percentage. The highest dressing percentages were noticed with dietary supplementation either with MOS or IMO compared to control group and represented (55%, 56% vs. 53%, respectively). Supplementing rabbits with MOS and IMO did not alter liver and kidney enzymes but supplementing (IMO) only increased blood total protein, albumin, while supplementing (MOS and IMO) improved A/G ratio significantly. In conclusion, Dietary supplementation of prebiotic oligosaccharides (MOS and IMO) provided beneficial effects on growth performance of rabbits, moreover, the recommended dose for supplementation of (MOS and IMO) in growing rabbits represented (3 and 0.5 kg /ton of ration respectively","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"T151 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125649393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chlorella Vulgaris Extract protects against Sodium Nitrite Toxicity in Male Rats","authors":"M. Eissa, Mohamed M. Ahmed, M. Attia, S. Orabi, A. Mousa, M. Mohamed","doi":"10.21608/djvs.2020.45000.1025","DOIUrl":"https://doi.org/10.21608/djvs.2020.45000.1025","url":null,"abstract":"The current study was carried out to investigate the protective potential of Chlorella Vulgaris (CV) extract against sodium nitrite toxicity. Fortyfive male Wister albino rats were assigned into 5 groups (n=9). Group (A) rats received normal saline orally for 3 months, Group (B): rats administered CV extract (70 mg/kg.BW) orally for 3 months, Group (C): rats received sodium nitrite (80 mg/kg.BW) orally for 3 months, Group (D): rats simultaneously received CV along with sodium nitrite treatment, orally, daily for 3 months, and Group (E): rats pre-treated with CV extract for 4 weeks followed by simultaneous treatment with sodium nitrite and CV extract for additional 8 weeks. Treatment of rats with sodium nitrite significantly increased serum urea and creatinine levels, associated with interstitial edema with mononuclear cells infiltrations, the renal tubular epithelium showed cloudy swelling and sever coagulative necrosis with desquamation of tubular epithelium and renal cast, the glomeruli showed congested glomerular capillaries. Besides, it decreased total leucocytic count and platelets count with normal hemoglobin, red blood cell count, hematocrit levels, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration. Pretreatment and co-treatment of sodium nitrite-treated rats with CV in groups (D & E) significantly prevented sodium nitrite-induced alterations of renal function and histological architecture. This study indicated that CV extract ameliorates the renal dysfunction induced by sodium nitrite toxicity.","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133176683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Dietary Bioorgano Supplementation with Inclusion of Q Z Toss™ on Nile Tilapia","authors":"A. Ismael, M. Elgohary, M. Tanekhy, A. Gaafar, A. Alsenosy, Abdalla Elbialy, Samar S. Abaza, M. Soliman","doi":"10.5455/DJVS.2019.17879.1003","DOIUrl":"https://doi.org/10.5455/DJVS.2019.17879.1003","url":null,"abstract":"The current study was designed to investigate the potential of bioorgano (thymol and carvacrol) with and without the water quality improvement product Q Z Toss™ on growth and health performance of Nile tilapia (Oreochromis niloticus). Six fish groups were maintained on control diet supplemented with the bioorgano for one month. Both bioorgano dietary levels exhibited significant increase in growth parameters as well as in white blood cell count with no negative impacts on both hepatic and renal functions. The histopathological examination revealed better intestinal epithelial status in bioorgano treated groups than other groups, and an increase in intestinal villi length regardless of bioorgano concentration used. while the posterior kidney showed activation of melanomacrophages centers (MMCs) which is linked to enhancement of fish immune response. Therefore, we can recommend the dietary inclusion of bioorgano in aqua-feed along with Q Z Toss™ application in rearing water as an efficient method to achieve feasible and sustainable fish production.","PeriodicalId":166243,"journal":{"name":"Damanhour Journal of Veterinary Sciences","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130038709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}