Journal of Oral and Maxillofacial Surgery最新文献

{"title":"Does Social Media Increase Perioperative Anxiety in Patients Undergoing Impacted Third Molar Surgery?","authors":"Ufuk Tatli DDS, PhD ,&nbsp;Tahayasin Kalkan DDS","doi":"10.1016/j.joms.2024.11.010","DOIUrl":"10.1016/j.joms.2024.11.010","url":null,"abstract":"<div><h3>Background</h3><div>In anticipation of third molar surgery, patients may experience increased anxiety. Patients frequently access social media platforms and view content about surgical treatments.</div></div><div><h3>Purpose</h3><div>The study purpose was to measure the level of perioperative anxiety of patients scheduled for third molar surgery exposed to social media and identify factors associated with patient anxiety.</div></div><div><h3>Study Design, Setting, Sample</h3><div>This is a prospective cohort study of patients undergoing impacted mandibular third molar surgery from September 2021 to August 2022 at the outpatient clinic of Cukurova University School of Dentistry.</div></div><div><h3>Predictor Variable</h3><div>The predictor variable was level of exposure to viewing third molar surgery-related social media before the surgery. Subjects were divided into 2 groups based on social media viewing preferences at their own discretion: the control group involved patients who did not view social media and study group involved patients who viewed social media before the surgery.</div></div><div><h3>Main Outcome Variables</h3><div>The outcome variables were patients' anxiety levels assessed using Modified Dental Anxiety Scale and Spielberger State Anxiety Inventory.</div></div><div><h3>Covariates</h3><div>Covariates were age, sex, education level, history of previous dentist visit, and impacted third molar surgery.</div></div><div><h3>Analyses</h3><div>Student t-test, Mann-Whitney U test, χ² test, Kruskal-Wallis test, one-way analysis of variance, and post hoc tests were used according to data. Level of significance was set at <em>P</em> &lt; .05.</div></div><div><h3>Results</h3><div>The study sample comprised 162 patients; 82 (50.6%) patients were in the control group and 80 (49.4%) were in the social media group. The Modified Dental Anxiety Scale scores of the social media group (11.95 ± 4.50) were statistically higher than the control group (9.66 ± 4.28) (<em>P</em> = .001). The Spielberger State Anxiety Inventory scores of the social media group (46.43 ± 5.80) were statistically higher than the control group (44.52 ± 5.53) (<em>P</em> = .03). There were statistical differences in anxiety levels considering some covariates. In social media group, there were some statistical differences in anxiety levels of patients who viewed different social media type and content.</div></div><div><h3>Conclusion and Relevance</h3><div>Patients who viewed social media on their own preferences before the surgery had higher perioperative anxiety compared to those who did not. The effects of demographic variables, different social media types and content on perioperative anxiety should be taken into account during stress management of the patients.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages 344-352"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of Orbital Fractures Caused by Sports Injuries in Children","authors":"Joyce Xu DMD, MD, MS ,&nbsp;Shelly Abramowicz DMD, MPH","doi":"10.1016/j.joms.2024.11.011","DOIUrl":"10.1016/j.joms.2024.11.011","url":null,"abstract":"<div><h3>Background</h3><div>Sports injuries account for 11.3 to 42.1% of the facial fractures. Injuries from contact with a ball, a bat or stick, or another player raise safety concerns.</div></div><div><h3>Purpose</h3><div>The purpose of this study was to assess the patterns of sports-related maxillofacial injuries involving orbital bone fractures in children.</div></div><div><h3>Study design, setting, and sample</h3><div>This was a retrospective case series of children who presented to Children's Healthcare of Atlanta from 2015 to 2021, with orbital injuries resulting from sports.</div></div><div><h3>Independent variable</h3><div>None.</div></div><div><h3>Outcome variable</h3><div>The outcome variables, including the fracture location, pattern, and the management of injury.</div></div><div><h3>Covariates</h3><div>The medical record were reviewed for the following variables: <em>1)</em> demographic information, <em>2)</em> mechanism of injury, <em>3)</em> type of sport, <em>4)</em> symptoms, <em>5)</em> length of inpatient stay, and <em>6)</em> duration of follow-up.</div></div><div><h3>Analysis</h3><div>Data were collected using a standardized collection form. Descriptive statistics were calculated.</div></div><div><h3>Results</h3><div>Overall, 101 patients (92 males) with an age of 13 ± 3 met the inclusion criteria. The most common sport was baseball or softball (n = 78, 77.2%). The mechanisms of injuries were largely due to collision with the ball (n = 79, 78.2%) or with another player (n = 13, 12.9%). Orbital fractures occurred mostly in the floor (n = 87, 86.1%), followed by the medial wall (n = 22, 21.8%), with an average of 1 surface involved. Maxillary sinus (n = 23, 22.8%) and/or nasal bone (n = 17, 16.8%) were the other facial bones outside of orbit commonly injured. The fractures patterns are minimally/nondisplaced (n = 68, 67.3%), displaced (n = 30, 29.7%), or comminuted (n = 3, 3%). The managements include surgical and nonsurgical. Twenty-three patients (22.8%) underwent surgical intervention. Twelve of them had an emergent operation due to extraocular muscle entrapment.</div></div><div><h3>Conclusion</h3><div>Sports injuries are a common cause of orbital trauma in children. Most injuries are due to baseball/softball from collision with the ball. They were mostly managed without surgery, except for the individuals that presented with entrapment, oculocardiac reflex, and a large-size defect. The information from this project could be utilized in implementing safety equipment use for participants to further prevent such injuries.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages 317-321"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AAOMS Author Disclosure forms","authors":"","doi":"10.1016/S0278-2391(25)00021-7","DOIUrl":"10.1016/S0278-2391(25)00021-7","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages A9-A11"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evolution of Virtual Surgical Planning in Craniomaxillofacial Surgery: A Comprehensive Review","authors":"Michael V. Joachim DMD, MSc, MHA ,&nbsp;Michael Miloro DMD, MD","doi":"10.1016/j.joms.2024.11.001","DOIUrl":"10.1016/j.joms.2024.11.001","url":null,"abstract":"<div><h3>Purpose</h3><div>Virtual surgical planning (VSP) has significantly transformed craniomaxillofacial surgery over the past 2 decades, leading to diverse applications and improved surgical outcomes. However, variations in technological approaches, clinical outcomes, and economic implications persist. This review aims to comprehensively examine the evolution of VSP in craniomaxillofacial surgery, assess its impact on surgical precision and patient outcomes, and identify current trends and future directions. A synthesis of current knowledge is essential to establish evidence-based guidelines for VSP implementation and optimize patient care in this rapidly advancing field.</div></div><div><h3>Methods</h3><div>A systematic literature search was conducted in PubMed, Embase, and IEEE Xplore databases from their inception to September 2024. Search terms included combinations of “virtual surgical planning” OR “computer-assisted surgery” AND “craniomaxillofacial” OR “maxillofacial” OR “craniofacial” AND “evolution” OR “development” OR “advancement”. From 540 initially identified articles, studies focusing on VSP in craniomaxillofacial surgery that reported technological advancements, surgical outcomes, or precision metrics were included. Eligible studies comprised case series with 5 or more subjects, comparative studies, and validation studies. Data extraction included study characteristics, technology details, surgical applications, outcome measures, and economic factors. Quality assessment was performed using appropriate tools based on study design.</div></div><div><h3>Results</h3><div>Out of 540 articles, 36 studies spanning from 1999 to 2024 met the inclusion criteria. The evolution of VSP was categorized into 3 phases: early foundations (1999 to 2004), expansion of applications and improved accuracy (2005 to 2014), and advanced integration with emerging technologies (2015 to 2024). Orthognathic surgery was the commonest application (52.8% of studies), followed by tumor resection and reconstruction (22.2%). Studies consistently demonstrated smaller linear discrepancies between planned and actual outcomes with VSP compared to conventional methods (VSP: 0.04 to 0.25 mm vs conventional: 0.29 to 1.33 mm). Recent advancements include the integration of artificial intelligence, mixed reality, and robotic systems, enhancing both preoperative planning and intraoperative guidance.</div></div><div><h3>Conclusion</h3><div>VSP has considerably evolved in craniomaxillofacial surgery, improving accuracy as demonstrated by reduced linear discrepancies between planned and actual outcomes across various procedures. While promising, challenges remain, including the need for standardization, comprehensive cost-effectiveness analyses, and long-term outcome studies.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages 294-306"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What are the Pterygomaxillary Fracture Patterns in Cleft Orthognathic Surgery?","authors":"Isabela Toledo Teixeira da Silveira MSc ,&nbsp;Bruno Gomes Duarte MSc ,&nbsp;Luciano Reis de Araújo Carvalho MSc ,&nbsp;Bhárbara Marinho Barcellos OMS ,&nbsp;Marina de Almeida Barbosa Mello MSc ,&nbsp;Renato Yassutaka Faria Yaedú PhD","doi":"10.1016/j.joms.2024.11.016","DOIUrl":"10.1016/j.joms.2024.11.016","url":null,"abstract":"<div><h3>Background</h3><div>Patients with cleft lip and palate (CLP) often exhibit unique anatomical variations in the pterygoid plates, which can influence fracture patterns at the pterygomaxillary junction (PMJ) during Le Fort I osteotomy. These differences may increase the risk of unfavorable fractures, complicating surgery and recovery.</div></div><div><h3>Purpose</h3><div>The study purpose was to measure the association between the osteotomy level with the PMJ fracture patterns in CLP patients undergoing Le Fort I osteotomy.</div></div><div><h3>Study Design, Setting, and Sample</h3><div>This retrospective cohort study included 100 patients with CLP, representing 200 tomographic views of the right and left pterygomaxillary regions. Preoperative tomographic scans were analyzed to measure morphometric features of the pterygomaxillary suture in the axial and sagittal planes.</div></div><div><h3>Predictor Variable</h3><div>The primary predictor was osteotomy level: at the level or above of the PMJ.</div></div><div><h3>Main Outcome Variable</h3><div>The main outcome was the pterygomaxillary fracture pattern, categorized as favorable or unfavorable.</div></div><div><h3>Covariates</h3><div>The covariates included age, sex, side of the mandible, pterygomaxillary suture thickness, pterygomaxillary suture width, distance between the greater palatine canal and the pterygoid suture, length of the medial plate, length of the lateral plate, insertion of the pterygomaxillary suture in the posterior part of the maxilla, and the length and height of the tuber.</div></div><div><h3>Analysis</h3><div>Statistical analyses included t-tests for mean differences (<em>P</em> &lt; .05) and χ² tests for associations. Relative risk was calculated for osteotomy levels to assess the significance of associations with fracture patterns.</div></div><div><h3>Results</h3><div>The study comprised 100 participants (47 men, 53 women), with a mean age of 23 years (SD = 2.31). In total, 110 (55%) fractures were classified as favorable. The frequency of unfavorable fractures was significantly higher when the osteotomy was performed above the PMJ (<em>P</em> &lt; .005). The relative risk for unfavorable fractures was 23.06 on the right side (95% confidence interval = [5.94, 89.53], <em>P</em> &lt; .001) and 65.00 on the left side (95% confidence interval = [9.30, 454.52], <em>P</em> &lt; .001).</div></div><div><h3>Conclusion</h3><div>The study findings suggest that in cleft surgery the osteotomy should be performed at the level of the PMJ to reduce the risk of inadvertent pterygomaxillary fractures.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages 307-316"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the Complexity of Arthroscopic Temporomandibular Joint Surgery Associated With Short-Term Complication Rates?","authors":"Daniel Jerez-Frederick DDS, MSc ,&nbsp;Daniela Albers DDS, Msc ,&nbsp;Carlos Fuenzalida DDS ,&nbsp;German Laissle DDS ,&nbsp;Camila Ávila-Oliver DDS, MSc","doi":"10.1016/j.joms.2024.11.008","DOIUrl":"10.1016/j.joms.2024.11.008","url":null,"abstract":"<div><h3>Background</h3><div>Arthroscopy is regarded as a minimally invasive surgical procedure, with complication rates ranging from 1.7 to 4.4%. It remains unclear whether the complexity of the arthroscopic procedure is associated with the frequency of complications.</div></div><div><h3>Purpose</h3><div>The study purpose was to measure the association between the level of arthroscopic complexity and short-term postoperative complications.</div></div><div><h3>Study Design, Setting, Sample</h3><div>The researchers implemented a prospective cohort study. Subjects presenting to Clinica Bupa Santiago, a tertiary care hospital in Chile between 2022 and 2023 who requires arthroscopy were enrolled. Inclusion criteria required subjects to have a history of joint disorder and a preoperative magnetic resonance imaging (MRI) to be scheduled for an arthroscopic surgery with a 6-month follow-up. Subjects lacking 6-month follow-up were excluded.</div></div><div><h3>Predictor Variable</h3><div>The predictor variable was the arthroscopy complexity level: level I (single puncture diagnostic sweep), level II (double puncture with instrumentation or shaver), and level III (discopexy or discectomy).</div></div><div><h3>Main Outcome Variable</h3><div>The main outcome variable was intraoperative and postoperative complications, which were defined as any unwanted development resulting in lasting consequences, additional surgeries, or unresolved issues, and these were coded as either present or absent.</div></div><div><h3>Covariates</h3><div>The covariates included age, sex, duration of symptoms, prior conservative therapies, history of previous open joint surgery, and Wilkes stage.</div></div><div><h3>Analyses</h3><div>Data were analyzed using descriptive statistics with statistical significance set at <em>P</em> value &lt;.05. χ² or Fisher’s exact test was used depending on the variable type.</div></div><div><h3>Results</h3><div>A total of 165 subjects (285 joints) with a mean age of 28.9 years (SD 13.0) were included. Of these, 149 (90.3%) were female and 16 (9.7%) were male. Level I procedures were performed on 37 joints (13.0%) in 23 subjects (16.3%), level II on 53 joints (18.6%) in 27 subjects (16.3%), and level III on 195 joints (68.4%) in 116 subjects (69.9%). Complications occurred only in level III (7 procedures, 2.5%, <em>P</em> = .33), affecting 5 subjects (3.0%). Observed complications included transient frontal facial paresis, mouth floor edema, transient neuropathic pain, suture rejection, and emphysema.</div></div><div><h3>Conclusion and Relevance</h3><div>The postoperative complication rate after arthroscopy was 2.5%, with no statistically significant association with operative complexity. Although more complications were observed in advanced arthroscopies, this increase was not significant.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages 270-278"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying Pain Subtypes in Patients With Craniofacial Lesions of Fibrous Dysplasia/McCune-Albright Syndrome","authors":"Camryn Berry BS ,&nbsp;Alison M. Boyce MD ,&nbsp;Leonard B. Kaban MD, DMD ,&nbsp;Zachary S. Peacock MD, DMD ,&nbsp;Michael Mannstadt MD ,&nbsp;Jaymin Upadhyay PhD","doi":"10.1016/j.joms.2024.12.001","DOIUrl":"10.1016/j.joms.2024.12.001","url":null,"abstract":"<div><h3>Background</h3><div>Fibrous dysplasia/McCune-Albright syndrome (FD/MAS) is a genetic disorder, marked by bone lesions, often affecting the craniofacial skeleton. Pain is a prevalent yet heterogeneous symptom reported by patients with craniofacial FD. Effective treatments are currently lacking, posing a significant clinical challenge to patient care.</div></div><div><h3>Purpose</h3><div>This preliminary study examined pain profiles in craniofacial FD and aimed to identify subtypes of patients based on pain phenotypes and emotional health.</div></div><div><h3>Study Design, Setting, Sample</h3><div>A prospective, cross-sectional study involving 15 patients with FD/MAS, conducted at Boston Children's Hospital and Massachusetts General Brigham's Hospitals.</div></div><div><h3>Predictor/Exposure/Independent Variable</h3><div>Headache frequency, craniofacial pain severity, neuropathic pain quality, pain interference, allodynia, photophobia, depression, and anxiety were assessed using clinical questionnaires.</div></div><div><h3>Main Outcome Variable(s)</h3><div>The primary outcome variable was the symptom profile derived from standardized clinical questionnaires and analyzed using principal component analysis and K-means clustering.</div></div><div><h3>Covariates</h3><div>Covariates included demographic data, diagnosis, and lesion location(s).</div></div><div><h3>Analyses</h3><div>Principal component analysis and K-means clustering of patient-reported measures of pain and emotional health were performed. Analysis of variance was conducted to determine significant differences among patient subtypes. Statistical significance was set at (<em>P</em> &lt; .05).</div></div><div><h3>Results</h3><div>The study included 15 subjects with FD/MAS, with a mean age of 36.2 (13.9) years, including 1 male. Clustering analysis identified 3 subtypes of patients with distinct symptom profiles. Cluster 1 (n = 2) averaged 70 (28.3) headache days in a 90-day period, pain level of 7.5 (0.7) on a 0-10 scale, and severe anxiety, depression, allodynia, photophobia, and pain interference. Cluster 2 (n = 7) patients reported an average of 5.4 (7.5) headache days, an average pain level of 2.7 (2.6), mild or no anxiety, depression, allodynia, photophobia, and pain interference. Cluster 3 (n = 6) patients displayed a mixed symptom profile with an average of 47.3 (36.4) headache days and a pain level of 5.25 (1.4). Notably, patients with temporal and skull base lesions were predominantly found in Clusters 1 and 3, which exhibited the most severe symptomatology.</div></div><div><h3>Conclusions and Relevance</h3><div>This study establishes a basis for future longitudinal research aimed at understanding underlying pain mechanisms and evaluating the response to personalized pain management strategies in subtypes of patients with craniofacial FD.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages 366-373"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"March 2025 AAOMS News and Announcements","authors":"","doi":"10.1016/j.joms.2024.12.007","DOIUrl":"10.1016/j.joms.2024.12.007","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages 393-396"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Medication-Related Osteonecrosis of the Jaw in Patients Receiving Antiresorptive Therapy Using Machine Learning Models","authors":"Kritsasith Warin DDS ,&nbsp;Sirasit Lochanachit PhD ,&nbsp;Praphan Pavarangkoon PhD ,&nbsp;Engkarat Techapanurak PhD ,&nbsp;Rachasak Somyanonthanakul PhD","doi":"10.1016/j.joms.2024.11.013","DOIUrl":"10.1016/j.joms.2024.11.013","url":null,"abstract":"<div><h3>Background</h3><div>Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication associated with the use of antiresorptive agents, impacting patient quality of life and treatment outcomes. Predictive modeling may aid in a better understanding of MRONJ development.</div></div><div><h3>Purpose</h3><div>The study aimed to evaluate machine learning (ML)–based models for predicting MRONJ in patients receiving antiresorptive therapy.</div></div><div><h3>Study Design, Setting, Sample</h3><div>This retrospective in silico study analyzed electronic medical records from Thammasat University Hospital, covering the period from January 2012 to December 2022. The sample included subjects receiving antiresorptive therapy, excluding those with a history of radiation therapy or metastatic jaw disease.</div></div><div><h3>Predictor Variables</h3><div>The primary predictor variable was the predicted probability of MRONJ development from the ML models.</div></div><div><h3>Outcome Variables</h3><div>The outcome variable was MRONJ status coded as present or absent based on chart review.</div></div><div><h3>Covariates</h3><div>Covariates included demographic data, MRONJ occurrence, location and staging of MRONJ, comorbidities, diseases related to antiresorptive agents, types of antiresorptive agents, therapy duration, concurrent medications, blood calcium levels, and dental factors.</div></div><div><h3>Analyses</h3><div>Model performance was assessed via accuracy, sensitivity, specificity, positive and negative predictive values, and the area under the receiver operating characteristic curve. Additionally, univariate and multivariate Cox regression analyses were conducted to identify factors significantly associated with MRONJ development. <em>P</em> ≤ .05 was statistically significant.</div></div><div><h3>Results</h3><div>The study analyzed data from 5,305 subjects with a mean age of 75 ± 11.1 years, predominantly female. MRONJ was observed in 81 cases (1.5%), with a median time to development of 33 months (interquartile range = 3). Among the 6 models tested, the best-performing model had an accuracy of 0.95 and an area under the receiver operating characteristic curve of 0.89-0.90. Significant predictors identified through Cox regression included metabolic syndrome (hazard ratio = 14.064, 95% confidence interval = 1.111-178.067, <em>P</em> = .041) and patients receiving intravenous pamidronate (hazard ratio = 5.932, 95% confidence interval = 1.755-20.051, <em>P</em> = .004), indicating their association with MRONJ development.</div></div><div><h3>Conclusions and Relevance</h3><div>ML-based predictive and time-to-event models effectively predict MRONJ risk, aiding in the strategic prevention and management for patients undergoing antiresorptive therapy.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages 353-365"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Value Proposition of Board Certification","authors":"Joseph E. Cillo Jr, DMD, MPH, PhD (Section Editor)","doi":"10.1016/j.joms.2024.12.003","DOIUrl":"10.1016/j.joms.2024.12.003","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"83 3","pages":"Pages 265-266"},"PeriodicalIF":2.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}