Jeffrey S Marschall, Logan Sardzinksi, Jeffrey Schootman, Steven Fletcher, Richard Burton
{"title":"Do Patient-Specific Distractors and Cutting Guides Reduce Operative Time in Infants Undergoing Mandibular Distraction Osteogenesis?","authors":"Jeffrey S Marschall, Logan Sardzinksi, Jeffrey Schootman, Steven Fletcher, Richard Burton","doi":"10.1016/j.joms.2026.03.017","DOIUrl":"https://doi.org/10.1016/j.joms.2026.03.017","url":null,"abstract":"<p><strong>Background: </strong>Mandibular distraction osteogenesis (MDO) is a surgical treatment for upper airway obstruction in infants with micrognathia. Recent advances in computer aided design and manufacturing (CAD/CAM) have enabled the use of patient-specific cutting guides and distractors; however, limited data exist regarding the effect of patient specific hardware on MDO operative time.</p><p><strong>Purpose: </strong>The purpose of this study was to evaluate if the use of stock distractors with patient-specific cutting guides or patient-specific mandibular distractors with patient specific cutting guides was associated with decreased operative time compared to stock distractors alone for infants who underwent MDO.</p><p><strong>Study design, setting, sample: </strong>A retrospective cohort study using consecutive cases was completed of infants treated with MDO at a single tertiary pediatric hospital between 2015 and 2026. Subjects older than 1 year of age or with incomplete data were excluded.</p><p><strong>Predictor variables: </strong>Predictor variables included hardware used (group 1: stock distractors alone; group 2: stock distractors with patient specific cutting guides; group 3: patient specific distractors with patient specific cutting guides), age at first surgery (days), weight at first surgery (kg), sex, and presence of a syndromic diagnosis.</p><p><strong>Outcome variables: </strong>The primary outcome variable was operative time (minutes).</p><p><strong>Covariates: </strong>Covariates included age, weight, sex, and syndromic diagnosis.</p><p><strong>Analyses: </strong>Descriptive statistics were calculated for all variables. Group comparisons were performed using Fisher's exact test or Kruskal-Wallis test. A linear regression model was constructed to identify independent predictors of operative time. Statistical significance was set at P< .05.</p><p><strong>Results: </strong>40 subjects were included in the analysis. Median age at surgery was 75 days (IQR, 30 to 133), and median operative time for the cohort was 198 minutes (IQR, 172 to 238). Stock distractors alone (group 1) were used in 15 (37.5%) cases, stock distractors with patient-specific cutting guides (group 2) in 15 (37.5%), and patient-specific distractors with patient-specific cutting guides (group 3) in 10 (25%). Median operative times were 232 minutes (IQR, 195 to 276), 184 minutes (IQR, 147 to 221), and 187 minutes (IQR, 171 to 228), respectively (P= .024). Linear regression demonstrated significantly reduced operative time with stock distractors with patient-specific cutting guides (β = -52 minutes; 95% CI, -86 to -18; P= .004) and with patient-specific distractors with cutting guides (β = -43 minutes; 95% CI, -81 to -4.7; P= .029).</p><p><strong>Conclusion/relevance: </strong>Use of patient-specific cutting guides and distractors during MDO is associated with a clinically meaningful reduction in operative time. These findings support the routine incorporat","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar A. Al-Aroomi MSc , Yanjing Ou PhD , Maria Nabil Aziz DDS , Peng Yuan Hu DDS , Jia Qi Shen DDS , Jiang Chen PhD
{"title":"Effectiveness of Concentrated Growth Factors in Reducing Postoperative Sequelae and Enhancing Healing Outcomes After Third Molar Extraction: A Systematic Review","authors":"Omar A. Al-Aroomi MSc , Yanjing Ou PhD , Maria Nabil Aziz DDS , Peng Yuan Hu DDS , Jia Qi Shen DDS , Jiang Chen PhD","doi":"10.1016/j.joms.2025.11.008","DOIUrl":"10.1016/j.joms.2025.11.008","url":null,"abstract":"<div><h3>Background</h3><div>Concentrated growth factors (CGFs) are autologous biomaterials with notable regenerative potential, particularly relevant in oral surgical applications. Optimizing postoperative recovery after third molar extraction is a clinically significant concern.</div></div><div><h3>Purpose</h3><div>This systematic review evaluates the effectiveness of CGFs in reducing postoperative sequelae and complications and in improving healing after third molar extraction in healthy adults. The primary outcomes assessed were pain and analgesic use, swelling, hemostasis, trismus, infection and dry socket, inferior alveolar nerve injury and paresthesia, fever, patient-reported outcomes, and satisfaction. Secondary outcomes included surgical duration, overall healing time, soft tissue recovery, radiographic bone fill, and periodontal parameters.</div></div><div><h3>Study Selection</h3><div>A comprehensive literature search was conducted across 11 databases up to April 2025, following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines and registered in the International Prospective Register of Systematic Reviews (PROSPERO) (CRD420251031885). Clinical studies involving healthy adults undergoing third molar extraction with or without CGF application were considered eligible based on population, intervention, comparison, outcomes, and study design framework. Of the 380 studies initially identified, 11 studies (2.9%) met eligibility; all were randomized clinical trials. Study quality was assessed using a modified Cochrane tool.</div></div><div><h3>Results</h3><div>Among the 11 included randomized clinical trials, 5 were rated as having unclear risk of bias, while the remainder demonstrated low risk, supporting the reliability of the findings. Due to high heterogeneity in study designs, methodologies, and outcomes, quantitative synthesis was not feasible. Pain improved in 6 of 8 (75%) studies, swelling in 4 of 7 (57%), and trismus in 2 of 4 (50%). Analgesic consumption decreased in 2 of 2 (100%) studies. Dry socket incidence was reduced in 1 of 3 (33%) of studies, while 2 showed no or nonsignificant differences. Soft-tissue healing improved in 2 of 2 studies, radiographic bone outcomes in 4 of 5 (80%), and periodontal parameters in 4 of 4 studies. Patient-reported outcomes improved in at least 1 domain in 2 of 2 studies.</div></div><div><h3>Conclusions and Relevance</h3><div>Within the limits of the current evidence, CGF appears to reduce postoperative pain and analgesic use, enhance soft-tissue healing, and show potential benefits in radiographic bone fill and periodontal outcomes distal to the second molar after third molar surgery. Its effects on swelling, trismus, and alveolar osteitis remain uncertain. Further well-designed, large-scale trials are needed to confirm these findings and clarify the role of CGF in routine practice. Registration: PROSPERO registration number: CRD420251031885.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 4","pages":"Pages 551-570"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jin-Beom Kim DDS , Jung-Sub An DDS, PhD , Kyung-Hoe Huh DDS, MSD, PhD , Sug-Joon Ahn DDS, MSD, PhD
{"title":"Does Temporomandibular Joint Disc Displacement Influence Joint Space Dimensions, and Does Sex Play a Role?","authors":"Jin-Beom Kim DDS , Jung-Sub An DDS, PhD , Kyung-Hoe Huh DDS, MSD, PhD , Sug-Joon Ahn DDS, MSD, PhD","doi":"10.1016/j.joms.2025.12.010","DOIUrl":"10.1016/j.joms.2025.12.010","url":null,"abstract":"<div><h3>Background</h3><div>Joint space dimensions influence maxillomandibular relationships by altering condylar position. Although disc displacement (DD) is the most common temporomandibular joint (TMJ) disorder, its effect on joint space dimensions and associated morphology remains unclear.</div></div><div><h3>Purpose</h3><div>This study aimed to determine whether DD status and sex are associated with differences in joint space dimensions and related bony morphology, based on combined TMJ magnetic resonance imaging and computed tomography (CT) evaluations.</div></div><div><h3>Study Design, Setting, Sample</h3><div>This retrospective cross-sectional study included patients who underwent paired magnetic resonance imaging and CT scans at Seoul National University Dental Hospital between 2008 and 2023. Exclusion criteria were congenital anomalies, systemic diseases, previous TMJ, orthodontic or orthognathic treatment, and trauma involving the TMJ.</div></div><div><h3>Predictor Variable</h3><div>The predictor variables were <em>1)</em> DD status, categorized as normal disc position (NR), DD with reduction, and DD without reduction and <em>2)</em> sex, coded as male or female.</div></div><div><h3>Main Outcome Variable</h3><div>The main outcome variable was joint space dimensions, selected for their influence on condylar position, including sagittal (anterior, superior, and posterior) and coronal (medial, central, and lateral) joint space distances (mm), and anterior, superior, posterior, and total joint space volumes (mm<sup>3</sup>).</div></div><div><h3>Covariates</h3><div>Age, CT modality (cone-beam CT vs multidetector CT), and laterality (right vs left) were considered as potential covariates.</div></div><div><h3>Analyses</h3><div>Linear mixed-effects models with a subject-level random intercept were applied, with Bonferroni and false discovery rate adjustments. Statistical significance was set at <em>P</em> < .05.</div></div><div><h3>Results</h3><div>The sample consisted of 85 subjects (24.6 ± 6.8 years), including 41 males (48.2%) and 44 females (51.8%). Age, CT modality, and laterality did not affect outcomes (<em>P</em> > .05). Compared with NR joints, DD joints exhibited a smaller condyle within a larger fossa (<em>P</em> < .05) and significantly greater anterior joint space distance in the sagittal plane, without differences in superior or posterior distances (<em>P</em> = .108 and <em>P</em> = 0.913, respectively). Coronal joint space distances did not show differences (<em>P</em> > .40). Anterior joint space volume was larger in DD joints than in NR joints (<em>P</em> < .001). Sex did not significantly influence these associations (<em>P</em> > .05).</div></div><div><h3>Conclusions and Relevance</h3><div>DD is associated with smaller condyles and enlarged fossa, contributing to increased anterior joint space dimensions. These findings may aid diagnosis and treatment planning in patients with TMJ DD.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 4","pages":"Pages 466-477"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145892573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tiebiao Wang DDS , Shuailin Peng DDS , Shuo Cui DDS , Weihong Xi DDS, PhD
{"title":"Is Double Anchorage Superior to Single Anchorage in Patients With Temporomandibular Joint Symptomatic Disc Displacement?","authors":"Tiebiao Wang DDS , Shuailin Peng DDS , Shuo Cui DDS , Weihong Xi DDS, PhD","doi":"10.1016/j.joms.2025.12.005","DOIUrl":"10.1016/j.joms.2025.12.005","url":null,"abstract":"<div><h3>Background</h3><div>For symptomatic anterior disc displacement without reduction, articular disc repositioning aims to enhance clinical function. It's unclear if double anchorage (DA) is superior to single anchorage (SA) in this procedure.</div></div><div><h3>Purpose</h3><div>The purpose of this study was to compare the therapeutic effects of DA or SA in subjects with temporomandibular joint symptomatic disc displacement (SDD).</div></div><div><h3>Study design, setting, sample</h3><div>The authors implemented a single-center retrospective cohort study. Subjects with Wilkes III-V stage SDD who underwent open temporomandibular joint disc plication at the Affiliated Stomatological Hospital of Nanchang University were identified via electronic medical records. The exclusion criteria of this study were as follows: (1) severe systemic diseases; (2) mental disorders; and (3) inability to complete follow-up.</div></div><div><h3>Predictor variable</h3><div>The predictor variable was the disc anchorage technique, which was grouped into DA and SA.</div></div><div><h3>Main outcome variable(s)</h3><div>The primary outcome variable was the therapeutic effect, including pain (assessed using the visual analog scale), maximal interincisal opening (MIO), and the craniomandibular index (CMI). The secondary outcomes were quality of life and postoperative disc position. Among these, visual analog scale, MIO, CMI, and quality of life were recorded at T0 (preoperation), T1 (1 month postoperation), T2 (3 months postoperation), and T3 (6 months postoperation); postoperative disc position was recorded between T2 and T3.</div></div><div><h3>Covariates</h3><div>The covariates included demographics (age, sex), perioperative variables (Wilkes stage,laterality (unilateral or bilateral), and presence or absence of perforation).</div></div><div><h3>Analyses</h3><div>Repeated measures analysis of variance (ANOVA) examined various effects. For primary outcomes, independent samples t-tests were used for between-group comparisons and paired t-tests for within-group comparisons, with significance set at <em>P</em> < .05.</div></div><div><h3>Results</h3><div>The sample included 137 subjects (DA: 70, 51%; SA: 67, 49%), with an overall mean age of 41.24 (±18.02) years and 19.0% female/81.0% male. For the DA and SA groups, mean pain reduction was from 6.30 (±1.34) to 0.73 (±0.92) and 6.00 (±1.60) to 1.33 (±1.16), mean MIO increase from 20.86 (±4.77) to 36.33 (±4.11) and 21.64 (±4.94) to 34.82 (±4.49), and mean CMI reduction from 0.51 (±0.10) to 0.13 (±0.11) and 0.47 (±0.14) to 0.18 (±0.12), respectively (all <em>P</em> < .05); all pairwise comparisons were significant (<em>P</em> < .05).</div></div><div><h3>Conclusion</h3><div>The results suggest that DA was associated with superior therapeutic effects compared to SA and is a suitable alternative in SDD surgery.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 4","pages":"Pages 449-465"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145966404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are You Scared Yet?","authors":"Thomas B. Dodson DMD, MPH (Editor-in-Chief)","doi":"10.1016/j.joms.2025.11.012","DOIUrl":"10.1016/j.joms.2025.11.012","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 4","pages":"Pages 435-436"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147578942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RE: Does Temporomandibular Joint Disc Displacement Influence Joint Space Dimensions, and Does Sex Play a Role?","authors":"Satya Ranjan Misra, Rupsa Das, Manmath Behera","doi":"10.1016/j.joms.2025.12.021","DOIUrl":"10.1016/j.joms.2025.12.021","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 4","pages":"Pages 445-446"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147578946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Şeyma Kale DDS , Ayşe Çakır Gündoğdu PhD , Halil Ayyıldız DDS , Berkan Altay DDS
{"title":"Effect of Systemic Oxytocin Administration on the Healing of Mandibular Fractures","authors":"Şeyma Kale DDS , Ayşe Çakır Gündoğdu PhD , Halil Ayyıldız DDS , Berkan Altay DDS","doi":"10.1016/j.joms.2025.11.017","DOIUrl":"10.1016/j.joms.2025.11.017","url":null,"abstract":"<div><h3>Background</h3><div>It has been determined that oxytocin (OT), a hormone primarily involved in childbirth and lactation, has anabolic effects on bone metabolism.</div></div><div><h3>Purpose</h3><div>The purpose of the study was to measure and compare radiographic and clinical fracture healing between the OT-treated and control groups.</div></div><div><h3>Study Design, Setting, and Sample</h3><div>This is an in vivo animal study using a mandibular fracture model in 42, 6-month-old male Wistar rats. The fracture line was created and fixed using mini plates and screws.</div></div><div><h3>Predictor Variables</h3><div>The predictor variable was OT exposure. The animals were randomly assigned to OT or control groups (C). The animals were sacrificed on days 10 (OT-10, C-10), 20 (OT-10, C-10), and 30, (OT-30, C-30) to evaluate the effect of OT on fracture healing at different stages. Thus, two groups and six subgroups were formed.</div></div><div><h3>Outcome Variables</h3><div>The outcome variable was fracture healing measured using gray values (GV), fracture healing scores (FHS), and the ratio of new bone area to total fracture area (NB/TF.) For an objective assessment of radiographic images, the average GV of the region can be calculated. FHS is a scoring system that evaluates bone healing. NB/TF is the ratio used to evaluate new bone formation.</div></div><div><h3>Covariates</h3><div>None.</div></div><div><h3>Analyses</h3><div>The differences between groups were analyzed using the independent samples test or the Mann–Whitney <em>U</em> test, depending on the distributional characteristics of the data. Comparisons between the control and experimental groups at each time point were performed using the independent samples test. Additionally, Pearson's or Spearman's correlation tests were used according to the distribution of the variables (<em>P</em> < .05).</div></div><div><h3>Results</h3><div>Compared to the C groups, OT groups consistently showed higher recovery outcomes. Although no significant difference was observed on day 10, on day 20, OT-20 subgroup demonstrated significantly higher GV (OT-20 = 1.35 ± 0.39, C-20 = 0.77 ± 0.24) (<em>P</em> = .011 < 0.05), FHS values (OT-20 = 7.83 ± 0.75, C-20 = 5.67 ± 1.21) (<em>P</em> = .004 < 0.05), and NB/TF ratios (OT-20 = 80.19 ± 4.93, C-20 = 31.40 ± 3.87) (<em>P</em> = .001 < 0.05). On day 30, OT-30 maintained this superiority, showing significantly higher GV, FHS, and NB/TF values compared to C-30 (all <em>P</em> < .05).</div></div><div><h3>Conclusions</h3><div>In this study, the groups treated with OT showed higher mean healing scores. Oxytocin improved the healing of mandibular bone fractures.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 4","pages":"Pages 518-528"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145810472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RE: \"Does Lateral Pterygoid Muscle Reattach After Ramus-Condyle Unit Reconstruction in Temporomandibular Joint Ankylosis Patients?\"","authors":"Anuj Jain MDS","doi":"10.1016/j.joms.2025.10.021","DOIUrl":"10.1016/j.joms.2025.10.021","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 4","pages":"Page 447"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147578642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does 810-nm Diode Laser Photobiomodulation Improve Sensory Recovery After Le Fort I Surgery?","authors":"Fatemeh Ostadkhalil DDS , Nima Dehghani DMD, OMFS , Ailar Yousefbeigi DDS, MSc , Mohadeseh Azarsina DDS, Ms , Neda Hakimiha DDS, PhD","doi":"10.1016/j.joms.2025.11.018","DOIUrl":"10.1016/j.joms.2025.11.018","url":null,"abstract":"<div><h3>Background</h3><div>Neurosensory disturbances are common after Le Fort I osteotomy, often transient but clinically relevant, highlighting the need for strategies to enhance recovery. Photobiomodulation (PBM) using low-level diode lasers has been proposed to accelerate nerve recovery.</div></div><div><h3>Purpose</h3><div>The purpose of study was to compare midface sensory recovery and subject satisfaction between PBM with an 810-nm diode laser and a control side (inactive probe) following Le Fort I osteotomy.</div></div><div><h3>Study Design, Setting, Sample</h3><div>A prospective triple-blind, split-face randomized controlled trial was conducted from 2021 to 2022 at 2 tertiary hospitals in Tehran. Eligible participants aged 18-40 years who underwent bimaxillary surgery with Le Fort I osteotomy. Exclusion criteria included trauma history, oral diseases, uncontrolled systemic diseases, and contraindications to laser therapy.</div></div><div><h3>Predictor Variable</h3><div>The predictor variable was the PBM treatment (810-nm GaAlAs diode laser). Treatments were randomly assigned to 1 side of the midface (PBM) while the contralateral side served as the control (inactive probe).</div></div><div><h3>Main Outcome Variable(s)</h3><div>The primary outcome variable was time to functional sensory recovery (FSR), defined as Medical Research Council Scale S3+. It was measured using a composite of standardized neurosensory tests (2-point discrimination, brush stroke directional, and thermal and sharp/blunt discrimination). Secondary outcomes included subject satisfaction, measured with a 10-point visual analog scale.</div></div><div><h3>Covariates</h3><div>Covariates included age, sex, and time since surgery.</div></div><div><h3>Analyses</h3><div>Descriptive statistics, Kaplan–Meier survival analysis, repeated-measures analysis of variance, and Mann–Whitney U tests were used. Statistical significance was set at <em>P</em> < .05.</div></div><div><h3>Results</h3><div>The study included 15 subjects (mean age 29.3 ± 7.0 years), with a 35-day follow-up. Median time to FSR was 28 days (interquartile range: 24-32) for the upper lip and 35 days (interquartile range: 30-40) for the nasolabial fold, with no statistically significant differences between PBM and control sides (Log-rank <em>P</em> > .05). Sensory function improved statistically significantly over time, but recovery trajectories did not differ between sides. Subject satisfaction was similar between groups.</div></div><div><h3>Conclusion and Relevance</h3><div>Postoperative PBM at 810 nm did not statistically significantly accelerate FSR compared to the control side. However, it was safe and associated with improved subject satisfaction at the final follow-up, suggesting a potential role in enhancing the subjective postoperative experience.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 4","pages":"Pages 501-508"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145810440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}