Journal of Microbiology and Infectious Diseases最新文献_第9页

Recurrence of SARS-CoV-2 RNA among Positive Covid-19 Cases Covid-19阳性病例中SARS-CoV-2 RNA的复发

Journal of Microbiology and Infectious Diseases Pub Date : 2021-03-15 DOI: 10.5799/jmid.951625

A. Singh, Ankur Kumar, V. Gaur, Indrani Adhikari, Rajesh Singh

引用次数: 0

Frequency of Bacteremia due to Carbapenemase-producing Enterobacteriaceae in Pediatric Hematology-Oncology Can Be Reduced by Measures of Hospital Infection Control 医院感染控制措施可降低儿童血液学肿瘤科产碳青霉烯酶肠杆菌引起菌血症的发生率

Journal of Microbiology and Infectious Diseases Pub Date : 2021-03-15 DOI: 10.5799/JMID.897193

D. Caselli

{"title":"Frequency of Bacteremia due to Carbapenemase-producing Enterobacteriaceae in Pediatric Hematology-Oncology Can Be Reduced by Measures of Hospital Infection Control","authors":"D. Caselli","doi":"10.5799/JMID.897193","DOIUrl":"https://doi.org/10.5799/JMID.897193","url":null,"abstract":"Objectives: The spread of carbapenemase-producing Enterobacteriaceae (CPE) is an emerging problem in children undergoing cancer-directed chemotherapy. A previous Italian survey reported a threefold increase in CPE colonization rate and a fourfold increase of CPE bloodstream infections in a 2 year-observation time interval. Methods: To assess the efficacy of the measures put in place to control this emergency, a second survey was performed in the years 2016-2017 and the results were compared. Results: The overall rate of colonization was comparable between the two study periods: 0.50% (2016-2017) vs. 0.48% (2012-2013). MDR/CPE bacteremia was now reported in 13 children from six centers. The rate of MDR/CPE bacteremia was 0.12 for 1,000 days of hospitalization (95% CI, 0.07-0.21) and compared favorably with that observed in the previous survey (0.42 for 1,000 days of hospitalization; 95% CI, 0.31-0.57; p<0.0001). The strains responsible for bacteremia were Klebsiella pneumonia in 9/13 children, Escherichia coli in 2/13, Citrobacter spp. and Stenotrophomonas maltophilia in one case each. The antibiotic susceptibility was available for 10 MDR/CPE strains. Conclusion: The number of patients colonized by CPE remained stable over the years, while the number of bloodstream infections decreased, as well as the resulting mortality. We conclude that children undergoing chemotherapy are at risk for CPE colonization/infection but the awareness of their colonization status may allow reducing CPE morbidity and mortality. J Microbiol Infect Dis 2021; 11(1):27-31.","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84503931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective 非侵入性鼻窦炎:临床和微生物学观点

Journal of Microbiology and Infectious Diseases Pub Date : 2021-03-15 DOI: 10.5799/JMID.897184

D. Sandhu, Veenu Gupta, D. Chhina, M. Munjal

{"title":"Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective","authors":"D. Sandhu, Veenu Gupta, D. Chhina, M. Munjal","doi":"10.5799/JMID.897184","DOIUrl":"https://doi.org/10.5799/JMID.897184","url":null,"abstract":"Objectives: Objectives: Fungal rhinosinusitis is one of the important healthcare problems and its incidence and prevalence are increasing over the past three decades. It affects approximately 20% of the population at some time in their lives. We aimed to identify and characterize the microorganisms causing non-invasive rhinosinusitis and to correlate the findings with the clinical profile of patients. Methods: Clinically suspected cases of rhinosinusitis were enrolled in the study and detailed clinical history was taken. Samples like nasal mucosa, nasal crusts, scrapings / excised nasal polyps, and biopsy were collected. The specimens were processed for fungal culture. Isolates were identified as per standard protocols. Results: A total of 74 patients clinically suspected of rhinosinusitis were enrolled in our study out of which 60.8% were males. The most common presenting complaint was nasal obstruction (91.8%) followed by nasal discharge (77%). Clinically characterizing, the most common type of non-invasive rhinosinusitis seen in our study was allergic rhinosinusitis (44.6%). KOH positivity was 45.6% and fungal culture positivity was 30.4%. The most common fungal isolate was Aspergillus flavus . Conclusion: and periodic evaluation of the patterns of isolates complications by early institution of appropriate treatment. J Microbiol Infect Dis 2021; 11(1):21-26.","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79669194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BK Virus Pneumonia with CMV Colitis in a Kidney Transplant Recipient: Successful Treatment with Non-Cidofovir Based Therapy 肾移植受者BK病毒肺炎合并巨细胞病毒结肠炎:非西多福韦治疗成功

Journal of Microbiology and Infectious Diseases Pub Date : 2021-03-15 DOI: 10.5799/JMID.897222

Ali Chaitou, M. Nasser, H. Karnib, Amal Hamieh

引用次数: 0

Changing Pattern of Resistance in Typhoid Fever in An Era of Antimicrobial Resistance: Is It Time to Revisit Treatment Strategies? 抗生素耐药性时代伤寒耐药模式的变化:是时候重新审视治疗策略了吗?

Journal of Microbiology and Infectious Diseases Pub Date : 2021-03-15 DOI: 10.5799/JMID.897134

S. Saxena, R. Kaur, V. Randhawa

{"title":"Changing Pattern of Resistance in Typhoid Fever in An Era of Antimicrobial Resistance: Is It Time to Revisit Treatment Strategies?","authors":"S. Saxena, R. Kaur, V. Randhawa","doi":"10.5799/JMID.897134","DOIUrl":"https://doi.org/10.5799/JMID.897134","url":null,"abstract":"Objectives: Multi-drug-resistant Salmonella Typhi is a major concern in the current era of antimicrobial resistance. The emergence of ceftriaxone-resistant Salmonella Typhi strains (CRST) has left very few therapeutic options for the treatment of these infections. The objective of this study was to evaluate the typhoid cases diagnosed with CRST and retrospectively analyze the antimicrobial sensitivity pattern of Salmonella Typhi over the past three years. Methods: Laboratory data from our hospital were reviewed for the past three years to examine the trends related to the isolation of Salmonella Typhi from blood and their antimicrobial susceptibility. The case records from the patients whose blood culture detected Ceftriaxone resistant Salmonella Typhi (CRST) were reviewed to assess the clinical condition and outcome. Results: Analysis of the antimicrobial susceptibility of Salmonella Typhi showed a decline in multidrug-resistant strains. Nalidixic acid resistance has remained high during this period. The resistance to ceftriaxone has shown an increase from 0% in 2016 to 11(12.6%) isolates in 2018. Also, azithromycin resistance has shown a steady increase from 0% in 2016, 3 (3.2%) in 2017 to 7 (8.5%) in 2018. There was no clustering of cases by time or space indicating a non-outbreak spread of ceftriaxone resistant strains. Conclusion: Development of resistance to ceftriaxone and azithromycin necessitates revision of therapeutic choices. All this necessitates an approach to do further extensive surveillance at the community level and improvement in hygiene, sanitation, and drinking water supply. Maybe it is time to revisit the older antibiotics such as ampicillin, cotrimoxazole, and chloramphenicol as therapeutic options for uncomplicated typhoid fever. J Microbiol Infect Dis 2021; 11(1):1-7.","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"250 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91533595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Microbial Etiology of Community Acquired Meningoencephalitis In Adults: A Retrospective Review 成人社区获得性脑膜脑炎微生物病原学的回顾性研究

Journal of Microbiology and Infectious Diseases Pub Date : 2021-03-15 DOI: 10.5799/JMID.897133

R. Vashisht, R. Gopalakrishnan, S. Nambi, D. Sureshkumar, N. Sethuraman, Yamunadevi Ramanathan, R. Venkatasubramanian

{"title":"Microbial Etiology of Community Acquired Meningoencephalitis In Adults: A Retrospective Review","authors":"R. Vashisht, R. Gopalakrishnan, S. Nambi, D. Sureshkumar, N. Sethuraman, Yamunadevi Ramanathan, R. Venkatasubramanian","doi":"10.5799/JMID.897133","DOIUrl":"https://doi.org/10.5799/JMID.897133","url":null,"abstract":"Objectives: Meningoencephalitis (ME) is a well-recognized clinical entity with diverse infectious etiologies. Only a few studies in the Indian literature are available on this issue, especially in the adult population. The aim is to study the microbial etiology of ME presenting to a tertiary care center. Methods: A total of 97 cases labeled as ME were initially found on review of hospital records in a retrospective review over 5 years. Of these, only 62 were microbiologically confirmed and these were selected for this study. Results: Bacteria were the cause in 21(34%) cases. Pneumococcus was the predominant bacterial etiology, found in 17 cases (detected by PCR in 15 and by culture in 3 cases). Viruses were seen in 13 (21%) cases; Herpes simplex virus (HSV) was seen in 4 cases and enterovirus and varicella in 2 cases each (all were detected by PCR). We also had Arboviruses: Chikungunya (3 cases) and Dengue (2 cases) (serological diagnosis). TB was found in 15 (24%) cases (diagnosed by positive CSF Xpert Mtb in 11 cases and by AFB culture in 7 cases). Cryptococcus was seen in another 13 (21%) cases (detected by positive CSF CRAG in all cases and culture positivity in 7 cases). Conclusion: Pneumococcus and HSV are the commonest agents causing acute ME syndrome. Mycobacterium tuberculosis and Cryptococcus accounted for all cases of chronic ME. Multiplex PCR (in acute ME) and Xpert Mtb and cryptococcal antigen (in chronic ME) play an important role in the diagnosis of culture-negative ME. J Microbiol Infect Dis 2021; 11(1):15-20.","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75604361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of Dengue epidemics in Northern Himalayan state of India: are we prepared enough 印度北喜马拉雅邦登革热流行的风险:我们是否准备充分

Journal of Microbiology and Infectious Diseases Pub Date : 2021-03-15 DOI: 10.5799/JMID.897241

G. Kumar, Shweta Pasi

引用次数: 1

Plasmid-mediated colistin resistance mcr-1 in a clinical isolate of Escherichia coli ST19 in Algeria 阿尔及利亚临床分离的大肠杆菌ST19质粒介导的黏菌素耐药mcr-1

Journal of Microbiology and Infectious Diseases Pub Date : 2020-12-15 DOI: 10.5799/jmid.839476

S. Bouheraoua, F. Assaous, Nora Zourdani, Naima Tahrat, Hassiba Tali Maamar

{"title":"Plasmid-mediated colistin resistance mcr-1 in a clinical isolate of Escherichia coli ST19 in Algeria","authors":"S. Bouheraoua, F. Assaous, Nora Zourdani, Naima Tahrat, Hassiba Tali Maamar","doi":"10.5799/jmid.839476","DOIUrl":"https://doi.org/10.5799/jmid.839476","url":null,"abstract":"We describe the emergence of plasmid-mediated colistin resistance mcr-1 in a clinical isolate of Escherichia coli ST19. The strain was isolated from a urine sample of a 75-year-old male patient. The identification was carried out by an automated system. The antibiogram was performed according to CLSI recommendations. The colistin MIC was determined by broth micro-dilution according to CA-SFM/EUCAST criteria. The detection of mcr-1 was carried out by immunochromatographic test and PCR mcr-1. Genetic transfers and determination of the plasmid incompatibility group were made. The ST was carried out by MLST using the Pasteur scheme. The strain has a high-level penicillinase resistance phenotype. It was susceptible to amikacin and resistant to gentamicin, tobramycin, fluoroquinolones, tetracycline, chloramphenicol, and cotrimoxazole. The strain was resistant to colistin (MIC ꞊ 4 μg/ml). The genetic transfer is given a colistin-resistant transconjugant. The plasmid carrying mcr-1 gene belongs to the incompatibility group IncHI2.The strain belongs to ST19. J Microbiol Infect Dis 2019; 10(4):222-224.","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76208040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global Analysis of COVID-19 Clinical Related Trials COVID-19临床相关试验全球分析

Journal of Microbiology and Infectious Diseases Pub Date : 2020-12-15 DOI: 10.5799/jmid.839379

M. Rathinasamy, Saritha Kandhasamy

引用次数: 3

Isolation of Eggerthella lenta from A Cutaneous Abscess Formed at Post-trauma Suture Site 从创伤后缝合处形成的皮肤脓肿中分离出大卵杆菌

Journal of Microbiology and Infectious Diseases Pub Date : 2020-12-15 DOI: 10.5799/jmid.839489

K. Chaudhari, Rakhi Biswas, C. Meghna, S. Sistla, K. Dharanipragada, B. Krishnan, R. Akhilesh

引用次数: 0