{"title":"COVID-19临床相关试验全球分析","authors":"M. Rathinasamy, Saritha Kandhasamy","doi":"10.5799/jmid.839379","DOIUrl":null,"url":null,"abstract":"Objectives: The aim of this study was to analyze clinical trials using topic modelling to identify emerging vaccine progression topics around the globe. Methods: The most important computational problem for the modeling of topics is using the observed documents to infer the hidden topic structure. The topic model was developed on the basis of data recorded on the WHO International Clinical Trials Registry Platform (ICTRP) between 3 February and 11 August 2020. Results: Show the top 10 topics based on the topic model that has been created. These topics are explored in the reviews and studies of clinical trials related to the development of the COVID-19 vaccine. Conclusion: This study aimed at the clinical trials registered at ICTRP and showed the recorded monthly clinical trials as well as the top 15 countries vying for the COVID-19 vaccine from 3 February to 11 August 2020. Using the dataset of the collected clinical trials, the topic model was developed to examine emerging trends in vaccine progression. J Microbiol Infect Dis 2020; 10(4):xxxxx. Keywords: COVID-19, Clinical trials, Vaccine progression, Emerging topics, Topic model","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"60 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Global Analysis of COVID-19 Clinical Related Trials\",\"authors\":\"M. Rathinasamy, Saritha Kandhasamy\",\"doi\":\"10.5799/jmid.839379\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objectives: The aim of this study was to analyze clinical trials using topic modelling to identify emerging vaccine progression topics around the globe. Methods: The most important computational problem for the modeling of topics is using the observed documents to infer the hidden topic structure. The topic model was developed on the basis of data recorded on the WHO International Clinical Trials Registry Platform (ICTRP) between 3 February and 11 August 2020. Results: Show the top 10 topics based on the topic model that has been created. These topics are explored in the reviews and studies of clinical trials related to the development of the COVID-19 vaccine. Conclusion: This study aimed at the clinical trials registered at ICTRP and showed the recorded monthly clinical trials as well as the top 15 countries vying for the COVID-19 vaccine from 3 February to 11 August 2020. Using the dataset of the collected clinical trials, the topic model was developed to examine emerging trends in vaccine progression. J Microbiol Infect Dis 2020; 10(4):xxxxx. Keywords: COVID-19, Clinical trials, Vaccine progression, Emerging topics, Topic model\",\"PeriodicalId\":16603,\"journal\":{\"name\":\"Journal of Microbiology and Infectious Diseases\",\"volume\":\"60 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Microbiology and Infectious Diseases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5799/jmid.839379\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Microbiology and Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5799/jmid.839379","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Global Analysis of COVID-19 Clinical Related Trials
Objectives: The aim of this study was to analyze clinical trials using topic modelling to identify emerging vaccine progression topics around the globe. Methods: The most important computational problem for the modeling of topics is using the observed documents to infer the hidden topic structure. The topic model was developed on the basis of data recorded on the WHO International Clinical Trials Registry Platform (ICTRP) between 3 February and 11 August 2020. Results: Show the top 10 topics based on the topic model that has been created. These topics are explored in the reviews and studies of clinical trials related to the development of the COVID-19 vaccine. Conclusion: This study aimed at the clinical trials registered at ICTRP and showed the recorded monthly clinical trials as well as the top 15 countries vying for the COVID-19 vaccine from 3 February to 11 August 2020. Using the dataset of the collected clinical trials, the topic model was developed to examine emerging trends in vaccine progression. J Microbiol Infect Dis 2020; 10(4):xxxxx. Keywords: COVID-19, Clinical trials, Vaccine progression, Emerging topics, Topic model
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