Ana Cláudia Vasconcellos Azeredo, André Külzer Santos, Raimunda Sinthia Lima de Braga, João Vitor Vigne Duz, Marina Scheffer de Souza, Denise Rossato Silva
{"title":"Prevalence and associated risk factors of post-COVID-19 syndrome in healthcare workers.","authors":"Ana Cláudia Vasconcellos Azeredo, André Külzer Santos, Raimunda Sinthia Lima de Braga, João Vitor Vigne Duz, Marina Scheffer de Souza, Denise Rossato Silva","doi":"10.1080/15459624.2024.2406233","DOIUrl":"10.1080/15459624.2024.2406233","url":null,"abstract":"<p><p>Given the global burden of COVID-19 among healthcare workers (HCWs), it is expected that they face an elevated risk of developing post-COVID-19 syndrome. The objectives of this study were to evaluate the prevalence of post-COVID-19 syndrome and associated risk factors in HCWs followed for a median time of 18 months by conducting a retrospective cohort study. All HCWs with confirmed COVID-19 during the period from January 2021 to December 2022 were included in the study. HCWs were regularly assessed after COVID-19 diagnosis, so post-COVID-19 syndrome data could be collected. During the study period, 463 HCWs were included in the study, 227 (49.0%) of which experienced post-COVID-19 syndrome. The most common persistent symptoms were fatigue (<i>n</i> = 147 [32.5%]), memory disorders (<i>n</i> = 98 [21.5%]), dyspnea (<i>n</i> = 73 [16.0%]), anxiety/depression (<i>n</i> = 69 [15.0%]), and cough (<i>n</i> = 43 [9.4%]). Female sex and obesity were statistically associated with the development of post-COVID-19 syndrome. A high prevalence of post-COVID-19 syndrome in HCWs was found. Female sex and obesity appear to be risk factors associated with a higher prevalence of post-COVID-19 syndrome. Special attention should be given to these patients with risk factors during follow-up in the COVID-19 recovery period.</p>","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":" ","pages":"843-846"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel Döhla, Elena Becker, Heike Granzer, Eugen Gubajdulin, Peter Langer, Christina Mutschnik, Patrick L Scheid, Jana Wiemann, Ralf M Hagen
{"title":"Successful establishment and evaluation of a reprocessing concept via steam at 105 °C for FFP masks in hospitals in case of logistic shortages.","authors":"Manuel Döhla, Elena Becker, Heike Granzer, Eugen Gubajdulin, Peter Langer, Christina Mutschnik, Patrick L Scheid, Jana Wiemann, Ralf M Hagen","doi":"10.1080/15459624.2024.2406237","DOIUrl":"10.1080/15459624.2024.2406237","url":null,"abstract":"<p><p>Filtering face piece (FFP) masks according to EN 149 <i>Respiratory protective devices - Filtering half masks to protect against particles - Requirements, testing, marking</i> are essential components of personal protective equipment against biological agents from an occupational health and hospital hygiene perspective. Therefore, shortages due to increased demand or supply bottlenecks can lead to staff threats due to the risk of infection. To determine whether FFP masks could be made reusable in a hospital setting, a thermal reprocessing concept (steam at 105 °C with a holding phase of 10 min) was evaluated in a bed reprocessing chamber. The results indicate that it is logistically possible to establish a reprocessing concept. Of 267 reprocessed masks, 48 were rejected by inspection because of defect strapping, trapped hair, misfolding, and missing lot number or deformation, and 22 masks were rejected by bacteriological examination because of contamination > 10 CFU of total bacteria per 25 cm<sup>2</sup> or the presence of <i>Staphylococcus aureus</i>. Two selected mask models maintained the expected mask performance equivalent to the FFP2 standard after reprocessing. Thermal reprocessing resulted in a virucidal effect. The results show that reprocessing of FFP masks in hospitals is possible. However, the success of reprocessing depends on the type of mask used. This study identified a suitable mask type for which the reported method is bactericidal and virucidal without impairing mask performance. The reported method required the use of a stationary hospital bed reprocessing chamber (sanitizing washer), so it cannot be used everywhere. Other methods and procedures should be tested to be independent of a bed reprocessing chamber and therefore may be more mobile and flexible.</p>","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":" ","pages":"895-908"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"2024 Author Index.","authors":"","doi":"10.1080/15459624.2024.2435783","DOIUrl":"https://doi.org/10.1080/15459624.2024.2435783","url":null,"abstract":"","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":"21 12","pages":"920-927"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reducing the particles generated by flushing institutional toilets. Part II: Assessing a portable and reusable toilet cover in U.S. hospitals.","authors":"Seth Eisenberg, Changjie Cai","doi":"10.1080/15459624.2024.2398752","DOIUrl":"10.1080/15459624.2024.2398752","url":null,"abstract":"<p><p>Flushing uncovered toilets in hospitals has been shown to produce toilet plume aerosols (TPA) in a wide size ranging from nanometers to micrometers. Studies have shown that TPA can carry infectious pathogens and hazardous drugs used in cancer treatment. To mitigate the risk of exposure, some researchers have recommended covering the toilet during flushing, and guidelines from the Oncology Nursing Society have specifically recommended covering the toilet when flushing excreta from patients receiving chemotherapy. Because existing literature primarily focused on controlled laboratory settings or small case studies, there has been a need for a real-world, multi-center study in clinical settings to measure TPA by flushing both covered and un-covered toilets. To address this gap, the authors initiated a multicenter study to measure TPA in clinical settings and to assess the effectiveness of a commercially available, portable, and reusable toilet cover. The study enrolled 15 hospital centers (145 toilets) in nine U.S. states which included seven National Cancer Institute (NCI)-designated comprehensive cancer centers. The particle number concentrations were measured using a TSI optical particle counter (TSI 9306) with six size bins (0.3 to 25.0 µm) positioned 22 inches above the floor. The results showed that the ambient particle number concentrations in the HEPA-filtered floor bathrooms (376 ± 857#/L) are significantly lower than the non-HEPA-filtered ones (7,432 ± 9,207#/L). The mean particle number concentrations generated by flushing are 3,951 ± 8,606#/L with a median of 1,916#/L, ranging from 136#/L to 71,959#/L. Results with cover demonstrated a reduction in the total number of particles of 101 ± 11% regardless of the HEPA filter usage (<i>p</i> = 0.0002 in the Mann-Whitney U test). Mixed-effects modeling revealed that the overall level of particle reduction is substantial regardless of state (nine total), floor levels, flush volumes, and inpatient versus outpatient. This study provides evidence supporting the use of the tested portable toilet cover as an intervention to reduce healthcare workers', patients', and visitors' exposure to toilet plume aerosols in clinical settings.</p>","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":" ","pages":"847-856"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karin Lovén, Lina Hagvall, Johannes Rex, Carina A Nilsson, Vilhelm Malmborg, Joakim Pagels, Bo Strandberg, Maria Hedmer
{"title":"Characterization of exposure to air pollutants for workers in and around fires.","authors":"Karin Lovén, Lina Hagvall, Johannes Rex, Carina A Nilsson, Vilhelm Malmborg, Joakim Pagels, Bo Strandberg, Maria Hedmer","doi":"10.1080/15459624.2024.2406244","DOIUrl":"10.1080/15459624.2024.2406244","url":null,"abstract":"<p><p>Firefighters can be occupationally exposed to a wide range of airborne pollutants during fire-extinguishing operations. The overall study aim was to characterize occupational exposure to smoke for several groups of workers responding to fires, with specific aims to determine the correlations between exposure markers and to biologically assess their systemic exposure to polycyclic aromatic hydrocarbons (PAHs) in urine. Personal exposure measurements of equivalent black carbon (eBC), elemental carbon (EC), organic carbon (OC), nitrogen dioxide (NO<sub>2</sub>), PAHs, lung deposited surface area (LDSA), and particle number concentration (PNC) of ultrafine particles were performed on firefighters, observers, and post-fire workers during firefighting exercises. Urine samples were collected before and after exposure and analyzed for PAH metabolites. Additional routes for PAH skin exposure were investigated by wipe sampling on defined surfaces: equipment, personal protective equipment (PPE), and vehicles. Among workers without PPE, observers generally had higher exposures than post-fire workers. The observers and post-fire workers had an occupational exposure to smoke measured e.g. as EC of 7.3 µg m<sup>-3</sup> and 1.9 µg m<sup>-3</sup>, respectively. There was a good agreement between measurements of carbonaceous particles measured as EC from filters and as eBC with high time resolution, especially for the observers and post-fire workers. Ultrafine particle exposure measured as LDSA was two times higher for observers compared to the post-fire workers. The urinary levels of PAH metabolites were generally higher in firefighters and observers compared to post-fire workers. Investigation of PAH contamination on firefighters' PPE revealed high PAH contamination on surfaces with frequent skin contact both before and after cleaning. Exposure to smoke can be assessed with several different exposure markers. For workers residing unprotected around fire scenes, there can be high peak exposures depending on their behavior concerning the smoke plume. Several workers had high urinary PAH metabolite concentrations even though they were exposed to low air concentrations of PAHs, indicating skin absorption of PAH as a plausible exposure route.</p>","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":" ","pages":"878-894"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fergus K O'Connor, Robert D Meade, Sean R Notley, Leonidas G Ioannou, Andreas D Flouris, Glen P Kenny
{"title":"Agreement between measured and self-reported physiological strain in young adults and older adults with and without common chronic diseases during simulated occupational heat stress.","authors":"Fergus K O'Connor, Robert D Meade, Sean R Notley, Leonidas G Ioannou, Andreas D Flouris, Glen P Kenny","doi":"10.1080/15459624.2024.2406227","DOIUrl":"10.1080/15459624.2024.2406227","url":null,"abstract":"<p><p>While monitoring physiological strain is recommended to safeguard workers during heat exposure, it is logistically challenging. The perceptual strain index (PeSI) is a subjective estimate thought to reflect the physiological strain index (PSI) that requires no direct monitoring. However, advanced age and chronic diseases (hypertension/type 2 diabetes [T2D]) influence the perception of heat stress, potentially limiting the utility of the PeSI. We therefore assessed whether the relation and agreement between the PeSI and PSI during simulated work in various environmental conditions is modified by age and T2D/hypertension. Thirteen young adults and 37 older adults without (<i>n</i> = 14) and with T2D (<i>n</i> = 10) or hypertension (<i>n</i> = 13) walked on a treadmill (∼200 W/m<sup>2</sup>) for 180 min or until termination (volitional fatigue, rectal temperature ≥39.5 °C) in 16, 24, 28, and 32 °C wet-bulb globe temperatures. Rectal temperature and heart rate were recorded to calculate PSI (0-10 scale). Rating of perceived exertion and thermal sensation were recorded to calculate PeSI (0-10 scale). The relation between hourly PSI and PeSI was assessed via linear mixed models. Mean bias (95% limits of agreement [LoA]) between PSI and PeSI was assessed via Bland-Altman analysis. PSI increased with PeSI (<i>p</i> < 0.001), but the slope of this relation was not different between young and older adults (<i>p</i> = 0.189) or as a function of chronic disease (within older adults; <i>p</i> = 0.183). The mean bias between PSI and PeSI was small (0.02), but the 95% LoA was wide (-3.3-3.4). Together, a linear relation between PeSI and PSI was observed but agreement between these measures varied considerably across individuals and thus PeSI should not be used as a surrogate marker of PSI. Caution should be taken when utilizing the PeSI to estimate physiological strain on workers.</p>","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":" ","pages":"869-877"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Airborne dust and bioaerosols in Canadian conventional and alternative houses for laying hens.","authors":"Magali-Wen St-Germain, Valérie Létourneau, Araceli Dalila Larios Martínez, Stéphane Godbout, Martine Boulianne, Caroline Duchaine","doi":"10.1080/15459624.2024.2406240","DOIUrl":"10.1080/15459624.2024.2406240","url":null,"abstract":"<p><p>Awareness about laying hen welfare has led to the phase-out of conventional battery cages in favor of the adoption of alternative housing systems for egg production in many countries. However, the greater freedom of movement for animals and the presence of manure and litter (sawdust, straw, feathers, etc.) on the floor in some alternative housing systems may be suitable conditions for dusts, bacteria, and fungi to be aerosolized, raising concerns about indoor air quality and respiratory health of workers. The present project aimed at assessing and comparing indoor air quality and bioaerosols in conventional and alternative houses for laying hens. Six were conventional houses (with battery cages), six were enriched colonies, and six were aviary (multi-level cage-free houses) visited in Eastern Canada from 2020-2022. Higher airborne concentrations of particulate matter (PM) from all size fractions (PM1, PM2.5, PM4, PM10, and total dust), culturable bacteria, total endotoxins, and <i>Clostridium perfringens</i> were found in aviaries compared to houses for laying hens in conventional and enriched colonies. Total endotoxin and <i>Clostridium perfringens</i> concentrations were higher in enriched colonies than in conventional laying-hen housing systems. <i>Campylobacter coli, Campylobacter jejuni,</i> and <i>Salmonella</i> sp. were detected in few hen houses. This study highlights possible markers for indoor air quality evaluation inside laying hen houses. These airborne contaminants could be targeted by mitigation strategies to improve indoor air quality in alternative housing systems for laying hens.</p>","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":" ","pages":"909-919"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Athena Rafieepour, Mansour R Azari, Iraj Alimohammadi, Ali Asghar Farshad
{"title":"The potential of Gol-e-Gohar iron ore mine airborne dust to induce toxicity in human lung A549 cells.","authors":"Athena Rafieepour, Mansour R Azari, Iraj Alimohammadi, Ali Asghar Farshad","doi":"10.1080/15459624.2024.2406235","DOIUrl":"10.1080/15459624.2024.2406235","url":null,"abstract":"<p><p>Airborne particulates in iron ore mining are a risk factor for adverse human lung effects. In this study, fine particulates deposited on surfaces of about 1.5 m above the ground and 6 meters from a milling unit of the Gol-e-Gohar iron ore mine were collected through wipe sampling. Dust particles less than 5 µm in diameter were separated with an electronic sieve. Aliquots were prepared from the sieved iron ore dust estimated to be equivalent to respiratory exposure in the iron ore mill in the concentrations of 1, 5, 10, 50, 100, and 250 µg/mL, which were intended to represent equivalent inhaled doses from working one month to a working life (25 years) in the mine. The airborne concentration of respirable particles was about five times the threshold limit value given (TLV<sup>®</sup>) for iron oxide published by the American Conference of Governmental Industrial Hygienists. The <i>in vitro</i> toxicity range was estimated to be equivalent to an accumulated dose associated with working from one month to a working life in the mine. Treatment of the A549 cells resulted in decreased dehydrogenase activity and cell glutathione content and increased reactive oxygen species (ROS) generation, mitochondrial membrane permeability, and cell apoptosis-necrosis rates. The results of this study revealed the possibility of lung damage at cell doses for respirable airborne iron oxide particles estimated to be equivalent to accumulated lifetime exposures among Gol-e-Gohar miners. Further studies are recommended to investigate the effect of actual contaminants in the workplace on the occurrence of health effects on workers.</p>","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":" ","pages":"857-868"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"\"The Action Level<sup>®</sup>\".","authors":"J Thomas Pierce","doi":"10.1080/15459624.2024.2435765","DOIUrl":"10.1080/15459624.2024.2435765","url":null,"abstract":"","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":" ","pages":"D23-D24"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William E Fayerweather, Nuttanit Pramounmat, Miriam M Higginbotham, David C Trumbore
{"title":"Development of emission factors for secondary organic aerosol precursors from in-service asphalt roofs using Monte Carlo-based quantitative uncertainty analysis.","authors":"William E Fayerweather, Nuttanit Pramounmat, Miriam M Higginbotham, David C Trumbore","doi":"10.1080/15459624.2024.2420994","DOIUrl":"10.1080/15459624.2024.2420994","url":null,"abstract":"<p><p>Several recent studies have examined the role of intermediate/semi-volatile organic compound emissions from paving and roofing asphalts in the formation of secondary organic aerosols (SOAs), which constitute a portion of fine atmospheric particulate matter. These studies have yielded divergent results. Building upon this research, this study aims to develop more representative emission factors for estimating the contribution of roofing materials to SOA formation. This was accomplished by investigating the impact on SOA formation of variables such as rooftop temperatures, solar insolation values, study durations, and the physical and chemical properties of the roofing materials tested. To quantify the influence of these variables, data from existing literature were drawn, and limited experimental lab work was conducted. Monte Carlo-based quantitative uncertainty and sensitivity analyses were completed to estimate more representative emission factors, generate accompanying uncertainty ranges, and rank critical parameters driving emissions that should be considered in any follow-up research. The emission factors developed in this study resulted in a central tendency estimate of 1.7 × 10<sup>-4</sup> Gg/yr SOA for the 720 hottest hours in Southern California, with a 90% confidence interval of 6.0 × 10<sup>-5</sup> to 3.4 × 10<sup>-4</sup> Gg/yr. For the 4,320 annual daylight hours, the central tendency estimate is 2.1 × 10<sup>-5</sup> Gg/yr, with a 90% confidence interval of 4.7 × 10<sup>-6</sup> to 5.1 × 10<sup>-5</sup> Gg/yr. To provide perspective, the results of this study indicate that the SOA contribution to in-service emissions from asphalt roofing surfaces is four to five orders of magnitude lower than that reported for mobile diesel and gasoline sources.</p>","PeriodicalId":16599,"journal":{"name":"Journal of Occupational and Environmental Hygiene","volume":" ","pages":"1-15"},"PeriodicalIF":1.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}