2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)最新文献

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Analysis of dynamic cell movement under AC electric field in 3D multi-layered microchannel 三维多层微通道中交流电场作用下细胞动态运动分析
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438285
Ryosuke Yuchi, Jiafeng Yao, Takeomi Mizutani, H. Obara, M. Sugawara, M. Takei
{"title":"Analysis of dynamic cell movement under AC electric field in 3D multi-layered microchannel","authors":"Ryosuke Yuchi, Jiafeng Yao, Takeomi Mizutani, H. Obara, M. Sugawara, M. Takei","doi":"10.1109/MHS.2015.7438285","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438285","url":null,"abstract":"In the field of regenerative medicine, it is expected to separate disease-causing cells from healthy cells by electrical method with label-free and high efficiency. The purpose of this study is to find the differences of speeds between disease-causing cells and healthy cells under alternating current electric field in 3D multi-layered microchannel. We prepared intracellular charge-differed two cell types: wild type cells (WT) and wild type cells with green fluorescent protein (GFP)-histone (GFP-HT). The cell dynamic movement of each type was detected by cell tracking. We found a difference between WT velocity and GFP-HT velocity around supplying electrode and discussed by particle tracking velocimetry. The present results provide a great significance for separation of disease-causing cells from healthy cells in the microchannel.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116145220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biological and biomaterial engineering approaches for injured brain regeneration 损伤脑再生的生物和生物材料工程方法
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438241
I. Ajioka
{"title":"Biological and biomaterial engineering approaches for injured brain regeneration","authors":"I. Ajioka","doi":"10.1109/MHS.2015.7438241","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438241","url":null,"abstract":"Functional tissue regeneration after brain injury requires cell replacement for dead neurons and rebuilding neural networks. Since brain injury is not recovered spontaneously in general, breakthrough technologies have been awaited for neural replacement. To develop new techniques for neural replacement, our research team has examined the proliferation potency of neurons by biological approach and has used artificial scaffolds for neural replacement by biomaterial engineering approach. In this symposium, I introduce our approaches for neural replacement and discuss the remaining issues to be solved for functional brain regeneration.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116241264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automatic stage construction for the support of micro object grasping 用于支持微物体抓取的自动工作台结构
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438324
Kotaro Yamamoto, M. Kojima, M. Horade, K. Kamiyama, Y. Mae, T. Arai
{"title":"Automatic stage construction for the support of micro object grasping","authors":"Kotaro Yamamoto, M. Kojima, M. Horade, K. Kamiyama, Y. Mae, T. Arai","doi":"10.1109/MHS.2015.7438324","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438324","url":null,"abstract":"Recently, observation and manipulation of cells and cell groups have been carried out by using micro hand. However, the common micro hand is fixed to the working environment. Therefore we cannot manipulate the object from various direction. We propose an automatic stage system which can eliminate the limitation of the manipulation direction of the micro hand.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126953998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new method for continuous sorting of cells/particles using lattice-shaped dual-depth microchannels 一种利用格子状双深度微通道连续分选细胞/颗粒的新方法
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438267
Takuma Yanai, M. Yamada, Wataru Seko, M. Seki
{"title":"A new method for continuous sorting of cells/particles using lattice-shaped dual-depth microchannels","authors":"Takuma Yanai, M. Yamada, Wataru Seko, M. Seki","doi":"10.1109/MHS.2015.7438267","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438267","url":null,"abstract":"In the last decade, various types of microfluidic cell/particle sorting devices have been developed, but most of these devices have limitations in terms of the relatively low throughput. In this paper, we describe a new scheme for continuous particle sorting, using high-density, lattice-shaped, and dual-depth microchannel networks. The lattice pattern composed of perpendicularly crossing deeper “main channels” and shallower “separation channels”, and the main channels are slanted against the overall flow direction. When particle suspension is continuously introduced, smaller particles reach the ceiling of the main channel, whereas larger particles do not. Consequently, larger particles enter the separation channels more frequently, resulting in the continuous particle separation. In the experiment, we successfully sorted microparticles based on size. In addition, the effects of the microchannel geometries and the vertical position of particles on the sorting efficiency were investigated. As application to biological samples, we demonstrated cell sorting using cultured mammalian cells. The presented mechanism of size-based particle sorting would be applicable to various research and industrial fields.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125984701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Ortholeg 2.0 - a new design for a lower limb active orthosis Ortholeg 2.0 -一个新的设计的下肢活动矫形器
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438347
M. Gloger, P. Alsina, N. Melo
{"title":"Ortholeg 2.0 - a new design for a lower limb active orthosis","authors":"M. Gloger, P. Alsina, N. Melo","doi":"10.1109/MHS.2015.7438347","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438347","url":null,"abstract":"This work describes mechanical design of a new active orthosis for lower limbs, called Ortholeg 2.0. New structure aims to be lighter than the original Ortholeg, in order to improve the user comfort, while increasing the ergonomic value. Durable but lightweight materials were chosen in order to ensure the safety during actions, such as walking, standing up, sitting. The embedded electronics will remain the same, as well as the actuators due to economic reasons. Sensory subsystem is not considered in this stage of the project but design includes possibility for future implementation of such components.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129812636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Search of the best slot rate of the slot addition type PZT actuator in a hollow tube micro pump 空心管微泵加槽式压电陶瓷作动器最佳槽速的研究
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438297
Hiromasa Suzuki, K. Tsuchiya, Y. Uetsuji
{"title":"Search of the best slot rate of the slot addition type PZT actuator in a hollow tube micro pump","authors":"Hiromasa Suzuki, K. Tsuchiya, Y. Uetsuji","doi":"10.1109/MHS.2015.7438297","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438297","url":null,"abstract":"Development of a micro fluid system is doing in recent years. A general micro fluid system, a flow channel and the pump part, other, it's separated. So miniaturization is difficult. As the countermeasure, the flow pass part and the pump part, technology of the hollow tube micro pump with which I united is applied. Ring type PZT is arranged to the needle top by applying the technology. Therefore a needle makes itself work as a pump. By the flow experiment, liquid transport in the tube of the hollow tube micro pump has been confirmed. Though, the flow rate through the tube is very small.Therefore, due to the radial direction of the deformation increase in the amount of ring type PZT, it is necessary to pump performance improvement. Check on the analysis that the amount of deformation increase is by adding a trench on the surface of the ring type PZT. However Optimization contributing trench condition deformation amount is not performed. Therefore, in order in this study to further improvement of the pump performance. The use of FEM analysis for ring type PZT, which went to a put a trench. Is one of the trench conditions, attention is focused on the trench rate. First, the static structural analysis is carried out to search for the best trench proportions. Then the modal analysis, the best trench ratio model and confirms the natural frequency. And performs frequency response analysis, and confirms the amount of deformation caused by each frequency. To target model which is arranged a PZT on the titanium tube. It will be fluid and the pump portion of the hollow tube micro pump. This is the evaluation value the amount of deformation and the generative force in the radial direction of the titanium tube inner surface. Most pump performance is I do the best percentage of the search to improve,","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130239279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication of hepatic lobule model based on electrodeposition 电沉积法制备肝小叶模型
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438237
Zeyang Liu, Masaru Takeuchi, M. Nakajima, T. Fukuda, Y. Hasegawa, Qiang Huang
{"title":"Fabrication of hepatic lobule model based on electrodeposition","authors":"Zeyang Liu, Masaru Takeuchi, M. Nakajima, T. Fukuda, Y. Hasegawa, Qiang Huang","doi":"10.1109/MHS.2015.7438237","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438237","url":null,"abstract":"This paper proposes an electrodeposition-based method to generate Alginate-Poly-L-lysine (PLL) microcapsules for 3D cell structures. Hepatic lobule shaped microcapsules of RLC-18 cells were produced for long-term culture to obtain desired morphologies of cell aggregates. The fabricated hepatic lobule models with high cell density are important to be applied for 3D assembly of biological cells for tissue engineering applications.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128877616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pilot study on control of one DoF manipulator on quadcopter for hammering check 四轴飞行器锤击检测单自由度机械臂控制的初步研究
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438311
Takahiro Ikeda, K. Ohara, A. Ichikawa, T. Fukuda
{"title":"Pilot study on control of one DoF manipulator on quadcopter for hammering check","authors":"Takahiro Ikeda, K. Ohara, A. Ichikawa, T. Fukuda","doi":"10.1109/MHS.2015.7438311","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438311","url":null,"abstract":"This paper describes a pilot study on control of one DoF manipulator on a quadcopter for hammering check of concrete bridges. The quadcopter leans its body due to an angle of an objective surface. Therefore, one DoF manipulator is required to keep an attitude of a hammering unit suitable for an inspection. We introduce our quadcopter with the manipulator and control strategy of the manipulator in this paper.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121467064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Kinematic analysis of low dimensional structure in walking and running 行走和奔跑低维结构的运动学分析
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438246
Shuntaro Ishiduka, H. Oshima, S. Aoi, T. Funato, N. Tomita, N. Tsujiuchi, Akihito Ito, K. Tsuchiya
{"title":"Kinematic analysis of low dimensional structure in walking and running","authors":"Shuntaro Ishiduka, H. Oshima, S. Aoi, T. Funato, N. Tomita, N. Tsujiuchi, Akihito Ito, K. Tsuchiya","doi":"10.1109/MHS.2015.7438246","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438246","url":null,"abstract":"Humans walk and run at various speeds by coordinating their whole-body movements skillfully, where they regulate the movements in accordance with the speed. However, it remains unclear what kinds of locomotion parameters they regulate and how to regulate the parameters. In the present study, to clarify the human strategy for regulating the whole-body movements in accordance with the speed, we measured human joint angles on sagittal plane during walking and running and analyzed the measured data by extracting low dimensional structure of the joint movements using singular value decomposition. Our results suggest a formation mechanism of human gaits, which contributes to elucidating the adaptation mechanism of human locomotion.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133886789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Morphology control of protein microparticles produced using microfluidic droplets in a non-equilibrium state 非平衡状态下微流控液滴产生的蛋白质微粒的形态控制
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438252
M. Yamada, Kazuma Takahashi, Ayaka Hori, S. Sugaya, M. Seki
{"title":"Morphology control of protein microparticles produced using microfluidic droplets in a non-equilibrium state","authors":"M. Yamada, Kazuma Takahashi, Ayaka Hori, S. Sugaya, M. Seki","doi":"10.1109/MHS.2015.7438252","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438252","url":null,"abstract":"Here we present microfluidic systems to produce micrometer-sized particles made of proteins, using monodisperse droplets in a non-equilibrium state. Droplets of an aqueous solution of protein were formed in the continuous phase of a water-dissolving polar organic solvent, and then the droplets were shrunk because of the dissolution of water molecules. Protein molecules were precipitated, and then stable protein microparticles were obtained after the crosslinking reaction. We obtained spherical/non-spherical protein microparticles using several types of proteins, and examined factors affecting the particle morphology. In particular, highly unique tear-drop-shaped particles and hemispherical particles were obtained when incompletely dehydrated droplets were crosslinked. In addition, we cultured mammalian cells on the particles made of collagen, demonstrating the applicability of the particles as cell-culture scaffolds. The presented protein microparticles would be useful as carriers or scaffolds for various biological/medical applications.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132321489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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