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2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)最新文献

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Automated construction system for cellular tissue based on laminar flow fibers 基于层流纤维的细胞组织自动构建系统
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2016-08-01 DOI: 10.1109/ICMA.2016.7558685
M. Kojima, M. Horade, Akira Fukushima, K. Ohara, S. Sakai, K. Kamiyama, Y. Mae, T. Arai
{"title":"Automated construction system for cellular tissue based on laminar flow fibers","authors":"M. Kojima, M. Horade, Akira Fukushima, K. Ohara, S. Sakai, K. Kamiyama, Y. Mae, T. Arai","doi":"10.1109/ICMA.2016.7558685","DOIUrl":"https://doi.org/10.1109/ICMA.2016.7558685","url":null,"abstract":"Cell tissue construction is one of the important issues for tissue engineering, which is a key-technology in regenerative medicine. Recently, several studies have reported, the in vitro fabrication of simple cell tissues. However, organs are made of some kinds of cells and they are complex tissues. Therefore, a technology to reproduce the complex structure and biological function of the organ is needed. In this paper, we propose an automated system for the construction of a cell tissue in vitro, based on hydrogel fiber.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"231 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134191172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterizing the biophysical properties of individual actin stress fibers 表征单个肌动蛋白应力纤维的生物物理特性
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438315
S. Deguchi, T. Matsui
{"title":"Characterizing the biophysical properties of individual actin stress fibers","authors":"S. Deguchi, T. Matsui","doi":"10.1109/MHS.2015.7438315","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438315","url":null,"abstract":"Actin stress fibers (SFs) play essential roles in cellular contractile force generation and resulting adhesion regulation. Although contractile properties of whole cells have been extensively studied, those intrinsic to individual SFs remain unknown. Here we isolate functional SFs from cells and directly measure the relationship between the shortening velocity and contractile forces generated by individual SFs. These isolated SFs are associated with major structural proteins typical for SFs present within intact cells, which include phosphorylated myosin regulatory light chain (MRLC) required for actin-myosin crossbridge cycling. Thus, contractile shortening of the structurally and functionally non-impaired SFs can be induced in vitro upon application of adenosine triphosphate. We then characterize their contractile properties using functionalized microneedles for physical manipulation and force measurement. SFs shorten quickly in the absence of external loading, whereas, interestingly, the shortening velocity is dramatically decreased by more than two orders of magnitude upon application of a small tensile load. These results show a highly steep shortening velocity-load relationship that is distinct from the hyperbolic Hill relation of skeletal myofibrils, which has been assumed in other studies to be valid for SFs as well because these two have similar sarcomeric patterns along their lengths.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115740772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of multifunctional robot hand for visual inspection equipped with 3D force sensing 具有三维力传感的多功能视觉检测机械手的研制
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438342
R. Akiyama, K. Kamiyama, M. Kojima, M. Horade, Y. Mae, T. Arai
{"title":"Development of multifunctional robot hand for visual inspection equipped with 3D force sensing","authors":"R. Akiyama, K. Kamiyama, M. Kojima, M. Horade, Y. Mae, T. Arai","doi":"10.1109/MHS.2015.7438342","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438342","url":null,"abstract":"In this paper, we design a robot hand for visual inspection equipped with 3D force sensing. The designed hand is attached to the tip of legs of multi-legged robot ASTERISK. The reason for the robot hand to be equipped to the tip of ASTERISK is that it could meet following four requirements. Firstly, the hand system can catch a 1cm size object such as bolts and wires. Secondly, a small camera is attached inside the hand for visual inspection. Thirdly, when moving, the hand will close and become regular tip of leg. Lastly, the hand can equip 3D force sensing ability.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116684775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A shooting robot based on the minimum actuator / sensor realization 一种基于最小致动器/传感器的射击机器人实现
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438303
M. Kawakami, M. Kaneko, K. Ohnishi
{"title":"A shooting robot based on the minimum actuator / sensor realization","authors":"M. Kawakami, M. Kaneko, K. Ohnishi","doi":"10.1109/MHS.2015.7438303","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438303","url":null,"abstract":"For a shooting robot capable of capturing a target, like casting manipulation, we discuss the issue on how many actuators and sensors are necessary and sufficient, since it is the core of the subject launching a rotating object with the angular velocity of ω and the releasing angle θ. In order to pre-determine the point( xl, yl ) where the object eventually lands, we create a mapping between the coordinates of ( xl, yl ) and (ω,θ). The experimental results show a fairly well match between the theoretical and experimental landing points where the difference is within 36 mm on average. Finally, we conclude that 1 linear actuator and 1 position sensor are necessary and sufficient for the proposed system.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117098044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improvement of operability of extra robotic thumb using tactile feedback by electrical stimulation 利用电刺激的触觉反馈改善额外机械拇指的可操作性
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438269
Masafumi Sobajima, Yuichiro Sato, Xufeng Wang, Y. Hasegawa
{"title":"Improvement of operability of extra robotic thumb using tactile feedback by electrical stimulation","authors":"Masafumi Sobajima, Yuichiro Sato, Xufeng Wang, Y. Hasegawa","doi":"10.1109/MHS.2015.7438269","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438269","url":null,"abstract":"The final goal of our research is to embody of an extra robotic thumb. In order to achieve this goal, we use tactile feedback. At first, we developed the extra robotic thumb which has three joints. It is attached on left hand and controlled by the right hand thumb. The robotic thumb takes the same motions as the right thumb does. Besides, a tactile sensor is equipped on the tip of the robotic thumb. The right thumb is stimulated through the electrical stimulation device depending on the tactile force measured by this sensor. This device has electrodes and the operator wears it on the tip of the right thumb. Bolts picking experiment is conducted using the robotic thumb. Two sets of the experiments are performed with or without the tactile feedback. As a result, operability of ERT got better with the tactile feedback.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129757934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Vectorial flow of phase-separated droplets in a mixture of water/organic solvent generated by a focused laser 聚焦激光产生的水/有机溶剂混合物中相分离液滴的矢量流动
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438260
S. Kimura, Takehiro Minami, K. Sadakane, T. Kenmotsu
{"title":"Vectorial flow of phase-separated droplets in a mixture of water/organic solvent generated by a focused laser","authors":"S. Kimura, Takehiro Minami, K. Sadakane, T. Kenmotsu","doi":"10.1109/MHS.2015.7438260","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438260","url":null,"abstract":"It is well known that a focus laser generate attractive and repulsive force. Focus laser induce flow of springing out droplet in water/organic solvent mixture of two-phase. We report that behavior of droplets are changed by condition of laser power focused. We observed that movement distance and initial velocity of the droplet is related to laser power. By the result of analysis, velocity which droplets spring out from focus point attenuated by surrounding medium resistance. Therefore, velocity of springing out are affected by laser power and medium resistance. And we observed that movement distance of droplet changes by reason of laser power.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128680766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on diffusion process of nanoparticles in a PDMS layer using SPT technique 利用SPT技术研究纳米粒子在PDMS层中的扩散过程
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438256
Ryo Iwao, Y. Matsuda, H. Yamaguchi, T. Niimi
{"title":"Study on diffusion process of nanoparticles in a PDMS layer using SPT technique","authors":"Ryo Iwao, Y. Matsuda, H. Yamaguchi, T. Niimi","doi":"10.1109/MHS.2015.7438256","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438256","url":null,"abstract":"The Brownian motions of ZnS-AgInS2 (ZAIS) nanoparticles in a poly(dimethylsiloxane) (PDMS) layer were observed using the single-particle tracking (SPT) technique. The positions of each nanoparticle can be detected with spatial resolution of O(10 nm), and reflect the environment near each nanoparticles; thus, SPT can obtain information on the nanoscale structure or the spatial heterogeneity of the medium. In this study, ZAIS nanoparticles were illuminated by an excitation laser, and the emission of the nanoparticle was taken by using an EM-CCD camera. We analyzed each motion of the nanoparticle in the PDMS layer under two conditions: before and after adding a curing agent. The histograms of the diffusion coefficients had single peak for all of the particles in the layer before adding the curing agent and some particles in the layer after adding the one. On the other hand, the histogram of the other particles had two peaks. This indicates these particles diffused in the heterogeneous layer, showing spatial heterogeneous curing process in the layer.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123681553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A component-based framework for molecular robotic development as smart drug system 基于组件的分子机器人智能药物系统开发框架
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438319
A. Wibowo, K. Sekiyama
{"title":"A component-based framework for molecular robotic development as smart drug system","authors":"A. Wibowo, K. Sekiyama","doi":"10.1109/MHS.2015.7438319","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438319","url":null,"abstract":"This paper presents a component-based framework for molecular robotic development. We proposed a new model for dynamic structural DNA nanotechnology, based on component for development of molecular robotics which parts can be composed, decomposed and replaced. Moreover, the molecular robotics model is designed to function as a drug delivery system. Molecular robots are structured from DNA, RNA, gels, and enzymes and include five components: the main body and the sensing, processing, actuating, and drug release components. We simulate the components and the framework mechanisms using Nucleic Acid Package software, Visual DNA strand displacement simulation, CadNano and Computer-aided engineering for DNA Origami.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121414859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
In-vitro DNA-based finite state machine 基于体外dna的有限状态机
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438306
R. Mardian, K. Sekiyama
{"title":"In-vitro DNA-based finite state machine","authors":"R. Mardian, K. Sekiyama","doi":"10.1109/MHS.2015.7438306","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438306","url":null,"abstract":"Molecular robotics and other autonomous molecular machines, like their conventional-mechanical counterparts, are expected to perform intelligent tasks under minimum external supervisions. One strategy to accomplish such complex design is to represent internal states of the machines by using finite state automaton (or also called finite state machine/FSM). The transition between states is triggered by external stimulus (can be input signals, sensing data from the environment, or the communication with other machines in the case of multi-agent systems). While there have been many proposals in implementing deterministic transitions by DNA reactions, e.g. by DNA strand displacement cascades, the experimental procedure still remains a challenge. Moreover, in this work, we also propose a new design for stochastic transitions, which also may be applied to arbitrary stochastic DNA computations.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132407331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of high speed measurement system for cell-scaffold interaction 细胞-支架相互作用高速测量系统的研制
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) Pub Date : 2015-11-01 DOI: 10.1109/MHS.2015.7438330
Y. Hirano, M. Kojima, M. Horade, K. Kamiyama, Y. Mae, T. Arai
{"title":"Development of high speed measurement system for cell-scaffold interaction","authors":"Y. Hirano, M. Kojima, M. Horade, K. Kamiyama, Y. Mae, T. Arai","doi":"10.1109/MHS.2015.7438330","DOIUrl":"https://doi.org/10.1109/MHS.2015.7438330","url":null,"abstract":"Cell-scaffold interaction is important for characterizing cell's mechanism such as differentiation or migration of cells. Therefore analyzing technique of the force exerted by a cell is required. In this research, we aim to realize high speed measurement of cellular traction force by applying the technique of existing vision-based tactile sensor. To achieve the measurement, we need to fabricate cellular scaffold which contain two layers of lattice patterned beads. In this paper, we report about fabrication process of the scaffold and experiment of cell culture on fabricated scaffold.","PeriodicalId":165544,"journal":{"name":"2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)","volume":"55 16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130114301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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