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Our Experience with the Use of Vasopressin in Hemodynamic Management of Shock and Outcome of Neonates 我们在新生儿休克血流动力学管理中使用血管加压素的经验和结果
Journal of Neonatology Pub Date : 2024-02-15 DOI: 10.1177/09732179231222729
Ravishankar Kanithi, Akhila Akula, Swapna Lingaldinna, Navya Bommidi
{"title":"Our Experience with the Use of Vasopressin in Hemodynamic Management of Shock and Outcome of Neonates","authors":"Ravishankar Kanithi, Akhila Akula, Swapna Lingaldinna, Navya Bommidi","doi":"10.1177/09732179231222729","DOIUrl":"https://doi.org/10.1177/09732179231222729","url":null,"abstract":"These retrospective observational data were collected to understand the role of vasopressin in the hemodynamic management of neonates with shock in a tertiary-level NICU over a period of 2 years. This included 28 neonate who received vasopressin for different clinical states with hypotension like septic shock, MAS with PPHN, Sepsis with PPHN, PPHN with CDH, HOCM, and even in end-organ injury (AKI) with sepsis. The response to vasopressin was 78.5% with improved signs of shock. The overall mortality rate was 15%. This is an attempt to understand vasopressin use in very sick neonates. Randomized controlled trials are required for its use as a treatment protocol.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":"116 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139776906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Barriers and Facilitators for Human Milk Donation and Acceptance Among Donors and Recipients 探索母乳捐赠的障碍和促进因素以及捐赠者和受捐者的接受程度
Journal of Neonatology Pub Date : 2024-02-15 DOI: 10.1177/09732179231222730
Vaishali Chaudhari, Sheila Aiyer
{"title":"Exploring Barriers and Facilitators for Human Milk Donation and Acceptance Among Donors and Recipients","authors":"Vaishali Chaudhari, Sheila Aiyer","doi":"10.1177/09732179231222730","DOIUrl":"https://doi.org/10.1177/09732179231222730","url":null,"abstract":"Background: There is no ideal alternative to mother’s own milk. In circumstances where an alternative is required, donated human milk is the best available option. To promote the establishment of more human milk banks, it is necessary to know the current attitude and awareness of the general population toward human milk donation as well as its acceptance. Methods: This is a qualitative study including focused group discussions and in-depth interviews. Results: Major barriers found to the donation of milk were fear of the insufficient amount of milk remaining for her baby, inconvenience due to stitch pain after lower segment caesarean section, not willing for pre-donation laboratory testing, the donation process being time-consuming, misconceptions like fear of disease transmission, and so on. Factors facilitating milk donation were breast engorgement and altruism. The facilitator for the acceptance of donated human milk was the belief that donated human milk was the best available option at that time. Barriers to acceptance of donated milk were fear of transmission of infections, prevalent misconceptions about donated human milk, and a lack of awareness regarding the process of pasteurization. Conclusion: Barriers to the donation of milk are related to inadequate knowledge, fear, and low awareness regarding human milk banking. Most mothers were encouraged to donate milk due to excess milk. A lack of knowledge about the process of pasteurization appears to be a significant barrier to the acceptance of donated milk. Pasteurized donated milk, being the only available superior option, made donated milk acceptable among the recipient’s relatives.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":"117 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139835963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Our Experience with the Use of Vasopressin in Hemodynamic Management of Shock and Outcome of Neonates 我们在新生儿休克血流动力学管理中使用血管加压素的经验和结果
Journal of Neonatology Pub Date : 2024-02-15 DOI: 10.1177/09732179231222729
Ravishankar Kanithi, Akhila Akula, Swapna Lingaldinna, Navya Bommidi
{"title":"Our Experience with the Use of Vasopressin in Hemodynamic Management of Shock and Outcome of Neonates","authors":"Ravishankar Kanithi, Akhila Akula, Swapna Lingaldinna, Navya Bommidi","doi":"10.1177/09732179231222729","DOIUrl":"https://doi.org/10.1177/09732179231222729","url":null,"abstract":"These retrospective observational data were collected to understand the role of vasopressin in the hemodynamic management of neonates with shock in a tertiary-level NICU over a period of 2 years. This included 28 neonate who received vasopressin for different clinical states with hypotension like septic shock, MAS with PPHN, Sepsis with PPHN, PPHN with CDH, HOCM, and even in end-organ injury (AKI) with sepsis. The response to vasopressin was 78.5% with improved signs of shock. The overall mortality rate was 15%. This is an attempt to understand vasopressin use in very sick neonates. Randomized controlled trials are required for its use as a treatment protocol.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":"42 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139836265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Barriers and Facilitators for Human Milk Donation and Acceptance Among Donors and Recipients 探索母乳捐赠的障碍和促进因素以及捐赠者和受捐者的接受程度
Journal of Neonatology Pub Date : 2024-02-15 DOI: 10.1177/09732179231222730
Vaishali Chaudhari, Sheila Aiyer
{"title":"Exploring Barriers and Facilitators for Human Milk Donation and Acceptance Among Donors and Recipients","authors":"Vaishali Chaudhari, Sheila Aiyer","doi":"10.1177/09732179231222730","DOIUrl":"https://doi.org/10.1177/09732179231222730","url":null,"abstract":"Background: There is no ideal alternative to mother’s own milk. In circumstances where an alternative is required, donated human milk is the best available option. To promote the establishment of more human milk banks, it is necessary to know the current attitude and awareness of the general population toward human milk donation as well as its acceptance. Methods: This is a qualitative study including focused group discussions and in-depth interviews. Results: Major barriers found to the donation of milk were fear of the insufficient amount of milk remaining for her baby, inconvenience due to stitch pain after lower segment caesarean section, not willing for pre-donation laboratory testing, the donation process being time-consuming, misconceptions like fear of disease transmission, and so on. Factors facilitating milk donation were breast engorgement and altruism. The facilitator for the acceptance of donated human milk was the belief that donated human milk was the best available option at that time. Barriers to acceptance of donated milk were fear of transmission of infections, prevalent misconceptions about donated human milk, and a lack of awareness regarding the process of pasteurization. Conclusion: Barriers to the donation of milk are related to inadequate knowledge, fear, and low awareness regarding human milk banking. Most mothers were encouraged to donate milk due to excess milk. A lack of knowledge about the process of pasteurization appears to be a significant barrier to the acceptance of donated milk. Pasteurized donated milk, being the only available superior option, made donated milk acceptable among the recipient’s relatives.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139776488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kangaroo Mother Care in a Tertiary Hospital in Northeast India: A 36-month Quality Improvement Initiative 印度东北部一家三级医院的袋鼠妈妈护理：为期 36 个月的质量改进计划
Journal of Neonatology Pub Date : 2024-02-08 DOI: 10.1177/09732179241228067
Rosina Ksoo, Himesh Barman, Ngoru Amila Monsang, Barihun Nongrum, Manisha De, Anna Choondal Simon
{"title":"Kangaroo Mother Care in a Tertiary Hospital in Northeast India: A 36-month Quality Improvement Initiative","authors":"Rosina Ksoo, Himesh Barman, Ngoru Amila Monsang, Barihun Nongrum, Manisha De, Anna Choondal Simon","doi":"10.1177/09732179241228067","DOIUrl":"https://doi.org/10.1177/09732179241228067","url":null,"abstract":"Background: Kangaroo mother care (KMC) is a special method of care for low birth weight and preterm babies by providing early and prolonged skin-to-skin contact with the mother and exclusive breastfeeding. It is a simple and cost-effective ways to take care of low-birth-weight babies. Objectives: To give KMC as a routine practice and to provide extended KMC to all eligible babies. Methodology: We conducted a Quality improvement (QI) study in our out-born neonatal unit from July 2020, and reviewed every six month till June 2023. A QI team comprising of staff nurses and doctors was formed. The root cause analysis for doing KMC was evaluated using a fishbone diagram, and the issues were addressed using prioritization matrix. Multiple Plan-Do-Study-Act (PDSA) cycles were conducted. Results were analysed using descriptive statistics. Results: A total of 105 babies were enrolled during this period. The mean gestation age was 32 ± 3.28 weeks. The average weight was 1577 ± 417 grams. Our baseline was two hours and 30 minutes per baby per day. We did a total of three PDSA cycles, and as of June 2023, we were able to give an average of 5.3 hours per baby per day. Conclusion: Our QI measures ensured that KMC was provided to all eligible low-birth-weight babies with proper documentation. Sensitizing and capacity-building our nursing staffs on KMC empowered them and helped to achieve and sustain our aim.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139791017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STrIP Score for Neonatal Jaundice: From Bench to Bedside 新生儿黄疸 STrIP 评分：从工作台到床边
Journal of Neonatology Pub Date : 2024-02-08 DOI: 10.1177/09732179241228081
Srinivasa Murthy D, S. Krishnegowda, Deepti Thandaveshwara
{"title":"STrIP Score for Neonatal Jaundice: From Bench to Bedside","authors":"Srinivasa Murthy D, S. Krishnegowda, Deepti Thandaveshwara","doi":"10.1177/09732179241228081","DOIUrl":"https://doi.org/10.1177/09732179241228081","url":null,"abstract":"Background: Non-invasive assessment of neonatal hyperbilirubinemia is done clinically with the Kramer scale and transcutaneous bilirubinometer. Recently, the Stool color for Triage of Infants needing Phototherapy (STrIP) score was studied and found to be better than both of the above methods in predicting measured serum bilirubin. This study sheds light on the clinical utility of the STrIP score in making therapeutic decisions. Method: This was a prospective study done in a tertiary-level neonatal unit. Breastfed term babies with clinical jaundice were recruited. The Kramer scale and STrIP score were performed on them and compared with respect to the therapeutic decision of commencing phototherapy based on measured serum bilirubin. Results: One hundred and twenty-eight infants were studied. The Kramer scale correctly aided the therapeutic decision on phototherapy (either to start or not to start) in 47 (36.7%) and the STrIP score in 119 (93%) of our subjects ( p = .0001). In 81 (63.2%) of the subjects, the Kramer scale underestimated the need for phototherapy. In contrast, the STrIP score overestimated the need for phototherapy in 11 (9%). Conclusion: The STrIP score helps in making more accurate therapeutic decisions in neonatal hyperbilirubinemia compared to the Kramer scale alone with respect to commencing phototherapy.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":" 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139792523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kangaroo Mother Care in a Tertiary Hospital in Northeast India: A 36-month Quality Improvement Initiative 印度东北部一家三级医院的袋鼠妈妈护理：为期 36 个月的质量改进计划
Journal of Neonatology Pub Date : 2024-02-08 DOI: 10.1177/09732179241228067
Rosina Ksoo, Himesh Barman, Ngoru Amila Monsang, Barihun Nongrum, Manisha De, Anna Choondal Simon
{"title":"Kangaroo Mother Care in a Tertiary Hospital in Northeast India: A 36-month Quality Improvement Initiative","authors":"Rosina Ksoo, Himesh Barman, Ngoru Amila Monsang, Barihun Nongrum, Manisha De, Anna Choondal Simon","doi":"10.1177/09732179241228067","DOIUrl":"https://doi.org/10.1177/09732179241228067","url":null,"abstract":"Background: Kangaroo mother care (KMC) is a special method of care for low birth weight and preterm babies by providing early and prolonged skin-to-skin contact with the mother and exclusive breastfeeding. It is a simple and cost-effective ways to take care of low-birth-weight babies. Objectives: To give KMC as a routine practice and to provide extended KMC to all eligible babies. Methodology: We conducted a Quality improvement (QI) study in our out-born neonatal unit from July 2020, and reviewed every six month till June 2023. A QI team comprising of staff nurses and doctors was formed. The root cause analysis for doing KMC was evaluated using a fishbone diagram, and the issues were addressed using prioritization matrix. Multiple Plan-Do-Study-Act (PDSA) cycles were conducted. Results were analysed using descriptive statistics. Results: A total of 105 babies were enrolled during this period. The mean gestation age was 32 ± 3.28 weeks. The average weight was 1577 ± 417 grams. Our baseline was two hours and 30 minutes per baby per day. We did a total of three PDSA cycles, and as of June 2023, we were able to give an average of 5.3 hours per baby per day. Conclusion: Our QI measures ensured that KMC was provided to all eligible low-birth-weight babies with proper documentation. Sensitizing and capacity-building our nursing staffs on KMC empowered them and helped to achieve and sustain our aim.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":"23 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139850840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STrIP Score for Neonatal Jaundice: From Bench to Bedside 新生儿黄疸 STrIP 评分：从工作台到床边
Journal of Neonatology Pub Date : 2024-02-08 DOI: 10.1177/09732179241228081
Srinivasa Murthy D, S. Krishnegowda, Deepti Thandaveshwara
{"title":"STrIP Score for Neonatal Jaundice: From Bench to Bedside","authors":"Srinivasa Murthy D, S. Krishnegowda, Deepti Thandaveshwara","doi":"10.1177/09732179241228081","DOIUrl":"https://doi.org/10.1177/09732179241228081","url":null,"abstract":"Background: Non-invasive assessment of neonatal hyperbilirubinemia is done clinically with the Kramer scale and transcutaneous bilirubinometer. Recently, the Stool color for Triage of Infants needing Phototherapy (STrIP) score was studied and found to be better than both of the above methods in predicting measured serum bilirubin. This study sheds light on the clinical utility of the STrIP score in making therapeutic decisions. Method: This was a prospective study done in a tertiary-level neonatal unit. Breastfed term babies with clinical jaundice were recruited. The Kramer scale and STrIP score were performed on them and compared with respect to the therapeutic decision of commencing phototherapy based on measured serum bilirubin. Results: One hundred and twenty-eight infants were studied. The Kramer scale correctly aided the therapeutic decision on phototherapy (either to start or not to start) in 47 (36.7%) and the STrIP score in 119 (93%) of our subjects ( p = .0001). In 81 (63.2%) of the subjects, the Kramer scale underestimated the need for phototherapy. In contrast, the STrIP score overestimated the need for phototherapy in 11 (9%). Conclusion: The STrIP score helps in making more accurate therapeutic decisions in neonatal hyperbilirubinemia compared to the Kramer scale alone with respect to commencing phototherapy.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemolytic Disease in Newborn Due to Jka Antibody: A Unique Clinical Presentation Jka 抗体导致的新生儿溶血病：一种独特的临床表现
Journal of Neonatology Pub Date : 2024-02-07 DOI: 10.1177/09732179231226058
Md Habibullah Sk, Ashadur Zamal, Bijan Saha
{"title":"Hemolytic Disease in Newborn Due to Jka Antibody: A Unique Clinical Presentation","authors":"Md Habibullah Sk, Ashadur Zamal, Bijan Saha","doi":"10.1177/09732179231226058","DOIUrl":"https://doi.org/10.1177/09732179231226058","url":null,"abstract":"Hemolytic disease in newborn results from alloimmune-mediated destruction of fetal or neonatal red blood cells caused by maternal alloantibodies. While ABO and Rh (D) incompatibilities are common causes, other minor antigenic mismatches such as Kidd are relatively infrequent. Here, we report a case of a female infant displaying conjugated hyperbilirubinemia and hepato-splenomegaly. Lab tests revealed both mother’s and baby’s blood groups as A positive, along with elevated reticulocyte count and a positive direct antiglobulin test. An abdominal ultrasound unveiled inspissated bile syndrome, likely due to calcium bilirubin sludge, leading to the conjugated hyperbilirubinemia. Further assessment revealed the infant and the father had a JKa-positive RBC phenotype, while the mother had a JKa-negative phenotype. This case highlights the significance of blood group antigen beyond the Rh system as a potential cause of hemolytic disease in newborn.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139797573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemolytic Disease in Newborn Due to Jka Antibody: A Unique Clinical Presentation Jka 抗体导致的新生儿溶血病：一种独特的临床表现
Journal of Neonatology Pub Date : 2024-02-07 DOI: 10.1177/09732179231226058
Md Habibullah Sk, Ashadur Zamal, Bijan Saha
{"title":"Hemolytic Disease in Newborn Due to Jka Antibody: A Unique Clinical Presentation","authors":"Md Habibullah Sk, Ashadur Zamal, Bijan Saha","doi":"10.1177/09732179231226058","DOIUrl":"https://doi.org/10.1177/09732179231226058","url":null,"abstract":"Hemolytic disease in newborn results from alloimmune-mediated destruction of fetal or neonatal red blood cells caused by maternal alloantibodies. While ABO and Rh (D) incompatibilities are common causes, other minor antigenic mismatches such as Kidd are relatively infrequent. Here, we report a case of a female infant displaying conjugated hyperbilirubinemia and hepato-splenomegaly. Lab tests revealed both mother’s and baby’s blood groups as A positive, along with elevated reticulocyte count and a positive direct antiglobulin test. An abdominal ultrasound unveiled inspissated bile syndrome, likely due to calcium bilirubin sludge, leading to the conjugated hyperbilirubinemia. Further assessment revealed the infant and the father had a JKa-positive RBC phenotype, while the mother had a JKa-negative phenotype. This case highlights the significance of blood group antigen beyond the Rh system as a potential cause of hemolytic disease in newborn.","PeriodicalId":16516,"journal":{"name":"Journal of Neonatology","volume":"273 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139857759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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