我们在新生儿休克血流动力学管理中使用血管加压素的经验和结果

Q4 Medicine

Journal of Neonatology Pub Date : 2024-02-15 DOI:10.1177/09732179231222729

Ravishankar Kanithi, Akhila Akula, Swapna Lingaldinna, Navya Bommidi

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引用次数: 0

摘要

收集这些回顾性观察数据的目的是了解血管加压素在三级新生儿重症监护室对休克新生儿进行血流动力学管理中的作用，这些数据的收集历时两年。其中包括 28 名新生儿，他们在不同的低血压临床状态下接受了血管加压素治疗，如脓毒性休克、MAS 伴 PPHN、败血症伴 PPHN、PPHN 伴 CDH、HOCM，甚至在败血症伴终末器官损伤（AKI）时也接受了血管加压素治疗。78.5%的患者对血管加压素反应良好，休克症状得到改善。总死亡率为 15%。这是了解在重症新生儿中使用血管加压素的一次尝试。将其用作治疗方案需要进行随机对照试验。

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Our Experience with the Use of Vasopressin in Hemodynamic Management of Shock and Outcome of Neonates

These retrospective observational data were collected to understand the role of vasopressin in the hemodynamic management of neonates with shock in a tertiary-level NICU over a period of 2 years. This included 28 neonate who received vasopressin for different clinical states with hypotension like septic shock, MAS with PPHN, Sepsis with PPHN, PPHN with CDH, HOCM, and even in end-organ injury (AKI) with sepsis. The response to vasopressin was 78.5% with improved signs of shock. The overall mortality rate was 15%. This is an attempt to understand vasopressin use in very sick neonates. Randomized controlled trials are required for its use as a treatment protocol.

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来源期刊

Journal of Neonatology Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.30

自引率

0.00%

发文量