Ross T Campbell, Kieran F Docherty, Carolyn S P Lam, David J Lowe, Mark C Petrie
{"title":"Reply to: Comment on \"Artificial Intelligence Fully Automated Analysis of Handheld Echocardiography in Real-World Patients with Suspected Heart Failure\".","authors":"Ross T Campbell, Kieran F Docherty, Carolyn S P Lam, David J Lowe, Mark C Petrie","doi":"10.1093/ejhf/xuag287","DOIUrl":"https://doi.org/10.1093/ejhf/xuag287","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Attanasio, Giandomenico Disabato, Gianluigi Guida, Federico Ambrogi, Piergiuseppe Agostoni, Giovanna Landi, Carlo Piccinni, Aldo P Maggioni, Massimo Piepoli
{"title":"Pharmacological optimisation in the treatment of Heart Failure in Women (PopS-HF): rationale and design of a prospective pragmatic, multicentre, randomised trial.","authors":"Andrea Attanasio, Giandomenico Disabato, Gianluigi Guida, Federico Ambrogi, Piergiuseppe Agostoni, Giovanna Landi, Carlo Piccinni, Aldo P Maggioni, Massimo Piepoli","doi":"10.1093/ejhf/xuag293","DOIUrl":"https://doi.org/10.1093/ejhf/xuag293","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yogesh N V Reddy, Javed Butler, Jan G P Tijssen, Faiez Zannad
{"title":"Interpreting potential benefit on secondary outcomes when a trial fails to meet its primary endpoint.","authors":"Yogesh N V Reddy, Javed Butler, Jan G P Tijssen, Faiez Zannad","doi":"10.1093/ejhf/xuag289","DOIUrl":"https://doi.org/10.1093/ejhf/xuag289","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148899810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayobami Omodara, Birgit Aßmus, Klaus K Witte, Sam Straw
{"title":"Hierarchical composite endpoints in heart failure trials: clarity or confusion?","authors":"Ayobami Omodara, Birgit Aßmus, Klaus K Witte, Sam Straw","doi":"10.1093/ejhf/xuag263","DOIUrl":"https://doi.org/10.1093/ejhf/xuag263","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148899890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolyn S P Lam, Tobin Joseph, Mohit Bhutani, Jingmin Zhou, Jonathan Purnell, Chris P Gale
{"title":"Pulmonary disease: the missing dimension in cardiovascular-kidney-metabolic syndrome.","authors":"Carolyn S P Lam, Tobin Joseph, Mohit Bhutani, Jingmin Zhou, Jonathan Purnell, Chris P Gale","doi":"10.1093/ejhf/xuag291","DOIUrl":"https://doi.org/10.1093/ejhf/xuag291","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148899883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristoffer Grundtvig Skaarup, Mats C H Lassen, Marat Yafasov, Manan Pareek, Sine H Christensen, Niklas Dyrby Johansen, Abby E Rudolph, Carmen Rodriguez-Tenreiro-Sánchez, Daniel Modin, Brian L Claggett, Carsten S Larsen, Lykke Larsen, Lothar Wiese, Michael Dalager-Pedersen, Matias G Lindholm, Anne Marie Reimer Jensen, Maria Dons, Katrine F Bernholm, Filip S Davidovski, Lisa Steen Duus, Camilla I Ottosen, Anne B Nielsen, Julie H Borchsenius, Caroline Espersen, Guldas Köse, Frederik H Fussing, Ingrid T Lenz, Jacob Christensen, Jakob Ø Simonsen, Majid Afzal, Katja V Bartholdy, Adam C F Langhoff, Lars Køber, Scott D Solomon, Jens Ulrik Stæhr Jensen, Cyril Jean-Marie Martel, Iago Giné-Vázquez, Carmen Duran-Parrondo, Marta Piñeiro-Sotelo, Martín Cribeiro-González, Mónica Conde-Pájaro, Susana Mirás-Carballal, Juan-Manuel González-Pérez, Bradford D Gessner, Negar Aliabadi, Claudia Schwarz, Mette Skovdal, Lawrence H Moulton, Pingping Zhang, Vanessa López-Gómez, Sabrina Welsh, Laura Anatale-Tardiff, Alejandro Cane, Kyla Hayford, Federico Martinón-Torres, Elizabeth Begier, Tor Biering-Sørensen
{"title":"RSV vaccine for preventing respiratory and cardiovascular hospitalizations in heart failure: a prespecified analysis of the extended DAN-RSV trial.","authors":"Kristoffer Grundtvig Skaarup, Mats C H Lassen, Marat Yafasov, Manan Pareek, Sine H Christensen, Niklas Dyrby Johansen, Abby E Rudolph, Carmen Rodriguez-Tenreiro-Sánchez, Daniel Modin, Brian L Claggett, Carsten S Larsen, Lykke Larsen, Lothar Wiese, Michael Dalager-Pedersen, Matias G Lindholm, Anne Marie Reimer Jensen, Maria Dons, Katrine F Bernholm, Filip S Davidovski, Lisa Steen Duus, Camilla I Ottosen, Anne B Nielsen, Julie H Borchsenius, Caroline Espersen, Guldas Köse, Frederik H Fussing, Ingrid T Lenz, Jacob Christensen, Jakob Ø Simonsen, Majid Afzal, Katja V Bartholdy, Adam C F Langhoff, Lars Køber, Scott D Solomon, Jens Ulrik Stæhr Jensen, Cyril Jean-Marie Martel, Iago Giné-Vázquez, Carmen Duran-Parrondo, Marta Piñeiro-Sotelo, Martín Cribeiro-González, Mónica Conde-Pájaro, Susana Mirás-Carballal, Juan-Manuel González-Pérez, Bradford D Gessner, Negar Aliabadi, Claudia Schwarz, Mette Skovdal, Lawrence H Moulton, Pingping Zhang, Vanessa López-Gómez, Sabrina Welsh, Laura Anatale-Tardiff, Alejandro Cane, Kyla Hayford, Federico Martinón-Torres, Elizabeth Begier, Tor Biering-Sørensen","doi":"10.1093/ejhf/xuag282","DOIUrl":"https://doi.org/10.1093/ejhf/xuag282","url":null,"abstract":"<p><p>Trial registration NCT06684743, registered 9 November 2024 (https://clinicaltrials.gov/study/NCT06684743).</p>","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148899833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Not All Left Bundle Branch Block Is Created Equal: The Role of Genotype in Dilated Cardiomyopathy.","authors":"Thomas Fink, Vanessa Sciacca, Philipp Sommer","doi":"10.1093/ejhf/xuag288","DOIUrl":"https://doi.org/10.1093/ejhf/xuag288","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martina Giusti, Pietro Giorgio Malvindi, Martina Benedetti, Fabio Vagnarelli, Carla Lofiego, Irene Capodaglio, Francesca Patani, Marco Marini, Gianfranco Sinagra, Christian Nitsche, Aldostefano Porcari, Marco Di Eusanio
{"title":"Early and Late TAVI Outcomes in Aortic Stenosis with Transthyretin Cardiac Amyloidosis: A Systematic Review.","authors":"Martina Giusti, Pietro Giorgio Malvindi, Martina Benedetti, Fabio Vagnarelli, Carla Lofiego, Irene Capodaglio, Francesca Patani, Marco Marini, Gianfranco Sinagra, Christian Nitsche, Aldostefano Porcari, Marco Di Eusanio","doi":"10.1093/ejhf/xuag285","DOIUrl":"https://doi.org/10.1093/ejhf/xuag285","url":null,"abstract":"<p><p>Concomitant transthyretin cardiac amyloidosis (ATTR-CA) is increasingly recognized among elderly patients with severe aortic stenosis (AS) referred to transcatheter aortic valve implantation (TAVI), yet its impact on early and late outcomes remains incompletely defined. We conducted a systematic review of studies comparing TAVI outcomes in patients with isolated AS and those with AS+ATTR-CA. Eleven observational studies were included, comprising 644,107 patients with isolated AS and 1,637 with AS+ATTR-CA. AS+ATTR-CA patients were older, more frequently male, and showed more atrial fibrillation, mildly reduced left ventricular ejection fraction, and markedly elevated cardiac biomarkers. Thirty-day mortality was low and similar between groups, with no consistent differences in stroke or major bleeding, whereas acute kidney injury and permanent pacemaker implantation were more frequent in AS+ATTR-CA. During follow-up, AS+ATTR-CA patients experienced higher heart failure readmissions and late all-cause mortality. ATTR-CA should not preclude TAVI but should inform risk stratification, peri-procedural management, and post-TAVI follow-up.</p>","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148885919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Aimo, Vincenzo Castiglione, Giuseppe Vergaro, Michele Emdin
{"title":"Estimating the prevalence of transthyretin cardiac amyloidosis in the general population.","authors":"Alberto Aimo, Vincenzo Castiglione, Giuseppe Vergaro, Michele Emdin","doi":"10.1093/ejhf/xuag286","DOIUrl":"https://doi.org/10.1093/ejhf/xuag286","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148878729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Misato Chimura, Kieran F Docherty, Aldo Pietro Maggioni, Roberto Latini, Muthiah Vaduganathan, Scott D Solomon, John J V McMurray
{"title":"Renin-independent aldosterone production in heart failure with reduced ejection fraction: A post hoc analysis of the ALOFT trial.","authors":"Misato Chimura, Kieran F Docherty, Aldo Pietro Maggioni, Roberto Latini, Muthiah Vaduganathan, Scott D Solomon, John J V McMurray","doi":"10.1093/ejhf/xuag290","DOIUrl":"https://doi.org/10.1093/ejhf/xuag290","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148885968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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