European Journal of Heart Failure最新文献

{"title":"Silencers versus stabilizers in amyloid cardiomyopathy. Are we asking the wrong questions?","authors":"Rodney H Falk, Sarah A M Cuddy, Osnat Itzhaki Ben Zadok","doi":"10.1002/ejhf.3614","DOIUrl":"https://doi.org/10.1002/ejhf.3614","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":16.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outpatient diuretic intensification across the cardiovascular‐kidney‐metabolic spectrum","authors":"Pedro Marques, João Pedro Ferreira","doi":"10.1002/ejhf.3611","DOIUrl":"https://doi.org/10.1002/ejhf.3611","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":"33 1","pages":""},"PeriodicalIF":18.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart failure guideline implementation in developing countries: A testimony from Syria.","authors":"Amr Abdin, Mohammad Bashar Izzat, Ahmad Rasheed Alsaadi, Asim Katbeh, Yassin Bani Marjeh, Suleman Aktaa","doi":"10.1002/ejhf.3625","DOIUrl":"https://doi.org/10.1002/ejhf.3625","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":16.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salt repletion and diuretic response: The role of serum chloride. A post‐hoc analysis of the SALT‐HF trial on furosemide and hypertonic saline solution administration in ambulatory patients with worsening heart failure","authors":"Julio Núñez, Gema Miñana, Rafael de la Espriella, Isabel Zegrí‐Reiriz, Josep Comín‐Colet, Jorge Rubio Gracia, Jose Luis Morales‐Rull, Pau Llàcer, Pablo Diez‐Villanueva, Javier de Juan Bagudá, Carolina Ortiz Cortés, Josebe Goirigolzarri‐Artaza, Jose Manuel García‐Pinilla, Elvira Barrios, Susana del Prado Díaz, Santiago Jiménez‐Marrero, Maria Alejandra Restrepo‐Córdoba, Jeffrey Testani, Marta Cobo Marcos","doi":"10.1002/ejhf.3597","DOIUrl":"https://doi.org/10.1002/ejhf.3597","url":null,"abstract":"AimsThe efficacy of combining hypertonic saline solution (HSS) with loop diuretics in worsening heart failure (WHF) remains uncertain. Hypochloraemia has been associated with reduced diuretic efficacy. Some authors propose that chloride repletion may enhance natriuretic and diuretic responses. This post‐hoc analysis of the SALT‐HF trial evaluated the effect of single‐dose administration of HSS plus intravenous (IV) furosemide versus IV furosemide, stratified by baseline serum chloride.Methods and resultsThe analysis included 148 ambulatory patients with WHF from the double‐blind, randomized SALT‐HF trial. Participants received either an IV single dose of HSS plus furosemide or IV furosemide. The endpoints were 3‐h urinary sodium excretion and diuresis, 7‐day congestion score, and 30‐day adverse events according to chloride levels. Multivariable linear and logistic regression models assessed the relationship between the intervention and the endpoints. The mean baseline serum chloride level was 100 ± 4 mmol/L. Sixteen patients (10.8%) were identified as hypochloraemic (serum chloride &lt;96 mmol/L), balanced between treatment groups. Patients with hypochloraemia showed a lower natriuretic response (<jats:italic>p</jats:italic> &lt; 0.05). Interaction analysis revealed a between‐treatment differential natriuretic effect based on the chloride levels (<jats:italic>p</jats:italic><jats:sub>interaction</jats:sub> = 0.008). HSS plus furosemide increased natriuresis compared to furosemide at lower chloride levels. No differential between‐treatment effect was found for 3‐h diuresis. Similar heterogeneous results were found for the 7‐day clinical congestion score and 30‐day heart failure events, with a benefit with HSS in patients with lower chloride levels.ConclusionIn ambulatory patients with WHF and hypochloraemia, adding HSS to furosemide may improve short‐term natriuretic response and outcomes. These findings suggest that chloride supplementation may help overcome diuretic resistance in these patients.","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":"78 1","pages":""},"PeriodicalIF":18.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143393116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Man versus machine in advanced heart failure: Can artificial intelligence beat clinicians?","authors":"Lucas Bacmeister, Pau Codina, Dirk Westermann","doi":"10.1002/ejhf.3609","DOIUrl":"https://doi.org/10.1002/ejhf.3609","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":"15 1","pages":""},"PeriodicalIF":18.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143393115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What can be done to improve the outcomes for cardiogenic shock patients with circulatory support devices?","authors":"Naoki Sato","doi":"10.1002/ejhf.3603","DOIUrl":"https://doi.org/10.1002/ejhf.3603","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":"12 1","pages":""},"PeriodicalIF":18.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Failure to improve cardiac remodelling and outcomes post-myocardial infarction: Insights from EMPRESS-MI","authors":"Francesco Fioretti, Gregg W. Stone, Javed Butler","doi":"10.1002/ejhf.3602","DOIUrl":"https://doi.org/10.1002/ejhf.3602","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":"13 1","pages":""},"PeriodicalIF":18.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empagliflozin's anti-inflammatory spectrum in type 2 diabetes mellitus: Piecing together the puzzle","authors":"Sophie Van Linthout, Frank Spillmann, Subodh Verma","doi":"10.1002/ejhf.3604","DOIUrl":"https://doi.org/10.1002/ejhf.3604","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":"161 1","pages":""},"PeriodicalIF":18.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rescuing patients with post‐myocardial infarction mitral regurgitation with transcatheter edge‐to‐edge repair: A salvation for all mechanisms of mitral regurgitation","authors":"Ali Vazir, Robert D Smith, Stephan Baldus","doi":"10.1002/ejhf.3605","DOIUrl":"https://doi.org/10.1002/ejhf.3605","url":null,"abstract":"","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":"15 1","pages":""},"PeriodicalIF":18.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comorbidity trajectories before and after the diagnosis of heart failure: A UK Biobank cohort study","authors":"Hugo MacGowan, Oliver I. Brown, Michael Drozd, Andrew M.N. Walker, Marilena Giannoudi, Sam Straw, Maria F. Paton, John Gierula, Melanie McGinlay, Kathryn J. Griffin, Klaus K. Witte, Mark T. Kearney, Richard M. Cubbon","doi":"10.1002/ejhf.3601","DOIUrl":"https://doi.org/10.1002/ejhf.3601","url":null,"abstract":"Heart failure (HF) is frequently associated with multiple comorbidities. We aimed to define their trajectory of accrual to identify opportunities for disease prevention.","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":"19 1","pages":""},"PeriodicalIF":18.2,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143393565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}