Journal of Medical Sciences最新文献

A New Self-expanding, Large-caliber Ureteral Stent Applied for Bilateral Long-segment Ureteral Strictures — A Case Report 应用新型自膨胀大口径输尿管支架治疗双侧长段输尿管狭窄--病例报告

Journal of Medical Sciences Pub Date : 2024-05-22 DOI: 10.4103/jmedsci.jmedsci_34_24

Hsuan-Yun Hsu, Chih-Wei Tsao

引用次数: 0

A Case Report of Video-assisted Thoracoscopic Pericardiectomy for Postpericardiotomy Recurrent Loculated Pericardial Effusion 视频辅助胸腔镜心包切除术治疗开胸术后复发性定位性心包积液的病例报告

Journal of Medical Sciences Pub Date : 2024-05-22 DOI: 10.4103/jmedsci.jmedsci_2_24

Hao-Wen Chang, Chen-Liang Tsai

{"title":"A Case Report of Video-assisted Thoracoscopic Pericardiectomy for Postpericardiotomy Recurrent Loculated Pericardial Effusion","authors":"Hao-Wen Chang, Chen-Liang Tsai","doi":"10.4103/jmedsci.jmedsci_2_24","DOIUrl":"https://doi.org/10.4103/jmedsci.jmedsci_2_24","url":null,"abstract":"\u0000 Surgical drainage, particularly pericardiotomy, which has a low recurrence rate, can safely and efficiently treat symptomatic pericardial effusion in patients with cancer. A thoracoscopic video-assisted pericardiectomy is an effective treatment option for rare instances of recurrent localized pericardial effusion. A 63-year-old male presented with a rare form of recurrent pericardial effusion that was initially circumferential, but recurred in a loculated form. On the right side, a loculated pericardial effusion caused right ventricular dysfunction and lower leg edema. The patient’s clinical symptoms, especially severe pedal edema, improved significantly after video-assisted thoracoscopic surgery with pericardiectomy through the right chest wall. Infrequent instances of recurrent loculated pericardial effusion after pericardiotomy may manifest with atypical symptoms. In addition to echocardiography, chest computed tomography can be used to examine in great detail local lesions caused by postoperative pericardial adhesions or scarring. Video-assisted thoracic surgery improves visualization and effectively treats loculated pericardial effusion during pericardiectomy.","PeriodicalId":16486,"journal":{"name":"Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141108887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamics of Urine Electrolytes in Term Neonates during the 1st Week of Life 足月新生儿出生后第一周尿液电解质的动态变化

Journal of Medical Sciences Pub Date : 2024-05-22 DOI: 10.4103/jmedsci.jmedsci_8_24

Sheng-Yuan Ho, Kai-Li Wang, Hueng-Chuen Fan, Jhao-Jhuang Ding

{"title":"Dynamics of Urine Electrolytes in Term Neonates during the 1st Week of Life","authors":"Sheng-Yuan Ho, Kai-Li Wang, Hueng-Chuen Fan, Jhao-Jhuang Ding","doi":"10.4103/jmedsci.jmedsci_8_24","DOIUrl":"https://doi.org/10.4103/jmedsci.jmedsci_8_24","url":null,"abstract":"\u0000 \u0000 \u0000 Urine electrolyte assessment is vital for diagnosing and managing neonatal conditions. However, the challenge of urine collection in neonates has resulted in a lack of standardized urine electrolyte reference values.\u0000 \u0000 \u0000 \u0000 This study seeks to explore the reference levels and potential trends in serum and urine electrolytes to better understand how the kidneys handle these substances.\u0000 \u0000 \u0000 \u0000 Healthy neonates were prospectively enrolled following normal births. Using biochemical methods, blood and urine samples were collected and analyzed on the 1st and 5th postnatal days. Statistical analysis was performed using descriptive statistics and the Wilcoxon matched-pairs signed-rank test.\u0000 \u0000 \u0000 \u0000 This prospective study enrolled 55 healthy neonates. Significant changes in serum electrolyte concentrations were observed between the 1st and 5th days after birth. Notably, sodium, creatinine, urea nitrogen, and uric acid levels decreased, whereas potassium, calcium, and phosphate levels increased. Urine analysis revealed significant increases in the tubular maximum phosphate reabsorption per glomerular filtration rate and decreases in the fractional excretion of potassium and uric acid by Day 5.\u0000 \u0000 \u0000 \u0000 This study challenges prevailing assumptions about the stability of neonatal urine electrolytes and highlights dynamic changes in the first postnatal week. These insights lay the groundwork for further research into electrolyte disorders in newborns and have potential implications for improving neonatal care practices.\u0000","PeriodicalId":16486,"journal":{"name":"Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141109146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extreme Delta Brush Electroencephalography Pattern in Anti-yo Encephalitis: A Case Report 反yo脑炎中的极端三角刷状脑电图模式：病例报告

Journal of Medical Sciences Pub Date : 2024-05-15 DOI: 10.4103/jmedsci.jmedsci_4_24

Fu-Yao Xiao, Yi Liu, Yu-Kai Lin, Chia-Kuang Tsai

{"title":"Extreme Delta Brush Electroencephalography Pattern in Anti-yo Encephalitis: A Case Report","authors":"Fu-Yao Xiao, Yi Liu, Yu-Kai Lin, Chia-Kuang Tsai","doi":"10.4103/jmedsci.jmedsci_4_24","DOIUrl":"https://doi.org/10.4103/jmedsci.jmedsci_4_24","url":null,"abstract":"\u0000 Autoimmune encephalitis is complex and gradually being recognized. Anti-N-methyl-D-aspartate Receptor (Anti-NMDAR) encephalitis was the most well-known and its unique electroencephalography (EEG) pattern is extreme delta brush (EDB). Anti-Yo encephalitits is far less than common anti-NMDAR encephalitis (anti-NMDARE). A 78-year-old male presented with progressive apathy, hypotension, unsteady gait, and depressed consciousness. EEG revealed an EDB pattern while the serum test was positive for anti-Yo antibodies. The patient then received 10 rounds of plasma exchange, and his blood pressure stability improved. Consequently, urine cytology and abdominal computed tomography revealed atypical cells and linear enhancement in the bladder dome, respectively. However, instead of further pathological confirmation and treatment, the patient’s family requested hospice care. As a result, the patient died of desaturation 7 days later after the withdrawal of ventilatory support. First recognized in 2012, EDB is believed to be specific to NMDARE. However, to date, EDB has not been well described, and no description is available regarding its reactivity. To our knowledge, this is the first case of EDB with anti-Yo encephalitis. Similar to the cases of EDB with anti-NMDARE, our patient did not have satisfied prognosis despite no further investigation and treatment of the possible underlying malignancy. As the prevalence and underlying mechanism of this EEG pattern are unclear, further studies are warranted to identify the potentially similar mechanisms and correlation between anti-NMDAR and anti-Yo encephalitis.","PeriodicalId":16486,"journal":{"name":"Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140973938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Alternative Way to Manage Intraoperative Tear of Cuff Inflation Line of the Endotracheal Tube during Ophthalmic Surgery 眼科手术中处理气管导管袖带充气线术中撕裂的另一种方法

Journal of Medical Sciences Pub Date : 2024-05-15 DOI: 10.4103/jmedsci.jmedsci_35_24

Shih-Syuan Lin, Zhi-Fu Wu, H. Lai

引用次数: 0

Pineapple (Ananas comosus) Ameliorates Depressant-like Behaviors in Rats Induced by Lipopolysaccharide 菠萝（Ananas comosus）可改善脂多糖诱发的大鼠抑郁样行为

Journal of Medical Sciences Pub Date : 2024-05-08 DOI: 10.4103/jmedsci.jmedsci_256_23

Herlin Ajeng Nurrahma, A. Meliala, Nura Eky Vikawati, Paramita Narwidina, Irwan Supriyanto

{"title":"Pineapple (Ananas comosus) Ameliorates Depressant-like Behaviors in Rats Induced by Lipopolysaccharide","authors":"Herlin Ajeng Nurrahma, A. Meliala, Nura Eky Vikawati, Paramita Narwidina, Irwan Supriyanto","doi":"10.4103/jmedsci.jmedsci_256_23","DOIUrl":"https://doi.org/10.4103/jmedsci.jmedsci_256_23","url":null,"abstract":"\u0000 \u0000 \u0000 Lipopolysaccharide (LPS) injection can lead to depression and mood disorders by reducing tryptophan availability through increased activity of the enzyme indoleamine 2,3-dioxygenase. Tryptophan, sourced from fruits such as pineapple (Ananas cosmosus), is vital for the body, especially the serotonergic system.\u0000 \u0000 \u0000 \u0000 This study aims to assess how pineapple pulp (PP) counters LPS-induced depressive behaviors in male Wistar rats.\u0000 \u0000 \u0000 \u0000 The experiment involved force-feeding PP for 28 days before LPS injection (0.5 mg/kg intraperitoneal [i.p.]) in 30 male Wistar rats, divided into five groups. Groups I (normal) and II (LPS control) received 15 ml aquadest/kg/day. Test Groups III, IV, and V were given varied doses of PP; low dose (3.75 ml/kg/day), medium dose (7.5 ml/kg/day), and high dose (15 ml/kg/day). At the study's end, rats underwent the open field test (OFT) and the tail suspension test (TST). In addition, blood and brain samples were analyzed for neuroendocrine markers related to depression.\u0000 \u0000 \u0000 \u0000 LPS triggers depressive symptoms, as evidenced by increased immobility time in the TST and altered behaviors indicative of anxiety in the OFT, especially in groups not receiving PP. This is followed by decreased serotonin levels in both plasma and brain when compared to groups given PP. In addition, higher corticosterone levels were observed in the LPS group than in the PP-treated group. Administering PP at 7.5 ml/kg/day for 28 days can alleviate the depressive effects induced by LPS injection.\u0000 \u0000 \u0000 \u0000 PP may have antidepressant properties, potentially by mitigating behaviors leading to depressive symptoms.\u0000","PeriodicalId":16486,"journal":{"name":"Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141001711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laparoscopic Hyperthermic Intraperitoneal Chemotherapy plus Neoadjuvant Intraperitoneal and Systemic Chemotherapy for Gastric Cancer with Malignant Ascites 腹腔镜腹腔内高温热化疗加新辅助腹腔内和全身化疗治疗伴恶性腹水的胃癌

Journal of Medical Sciences Pub Date : 2024-04-22 DOI: 10.4103/jmedsci.jmedsci_133_23

Hsing-Wei Yu, G. Liao, Ting-Ying Lee, De-Chuan Chan

{"title":"Laparoscopic Hyperthermic Intraperitoneal Chemotherapy plus Neoadjuvant Intraperitoneal and Systemic Chemotherapy for Gastric Cancer with Malignant Ascites","authors":"Hsing-Wei Yu, G. Liao, Ting-Ying Lee, De-Chuan Chan","doi":"10.4103/jmedsci.jmedsci_133_23","DOIUrl":"https://doi.org/10.4103/jmedsci.jmedsci_133_23","url":null,"abstract":"\u0000 \u0000 \u0000 Patients with gastric cancer (GC) and malignant ascites (MA) usually have poor outcomes and a high risk of recurrence and mortality, even after curative gastrectomy or chemotherapy. Systemic chemotherapy has been prescribed for patients with GC and MA; however, most of these patients expire within 1 year.\u0000 \u0000 \u0000 \u0000 To evaluate the outcomes of laparoscopic hyperthermic intraperitoneal chemotherapy (LHIPEC) plus neoadjuvant intraperitoneal and systemic chemotherapy (NIPS) in the outcomes of GC patients with MA.\u0000 \u0000 \u0000 \u0000 We enrolled 62 patients with GC and MA between January 1, 2016, and March 1, 2021. Four patients were excluded because of extraperitoneal metastasis, and two patients were ineligible. A total of 56 patients underwent biweekly staging laparoscopy and LHIPEC with NIPS. We also performed staging laparoscopy to evaluate the effectiveness of LHIPEC + NIPS.\u0000 \u0000 \u0000 \u0000 The mean survival time of the 56 patients was 20.8 months. The overall complication rate was 33.93%. After the LHIPEC + NIPS intervention, the peritoneal cancer index score (P < 0.001), ascites volume (P = 0.003), and cytology (P < 0.001) significantly improved compared to before the intervention; quality of life (Eastern Cooperative Oncology Group) was also better than before the intervention (P = 0.002), and no discomfort was noted postintervention.\u0000 \u0000 \u0000 \u0000 LHIPEC + NIPS is feasible for the treatment of GC with MA and may improve patients’ quality of life.\u0000","PeriodicalId":16486,"journal":{"name":"Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140675117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combination of Remimazolam and Remifentanil for Procedural Sedation and Analgesia in a Patient with Morbid Obesity Undergoing Gastrointestinal Endoscopy under Continuous Positive Airway Pressure: A Case Report 在持续气道正压下为一名接受消化道内窥镜检查的病态肥胖患者联合使用雷马唑仑和雷米芬太尼进行手术镇静和镇痛：病例报告

Journal of Medical Sciences Pub Date : 2024-04-17 DOI: 10.4103/jmedsci.jmedsci_280_23

Chih-Wei Lin, Kuang-I Cheng, Zhi-Fu Wu

引用次数: 0

Self-limiting Skin Rash Found in a Patient with Suspected Malignant Hyperthermia Attack - A Case Report 疑似恶性高热惊厥患者的自限性皮疹--病例报告

Journal of Medical Sciences Pub Date : 2024-04-12 DOI: 10.4103/jmedsci.jmedsci_270_23

Yu-Chi Tu, Po-Yang Chen, Kuang-I Cheng, Zhi-Fu Wu

{"title":"Self-limiting Skin Rash Found in a Patient with Suspected Malignant Hyperthermia Attack - A Case Report","authors":"Yu-Chi Tu, Po-Yang Chen, Kuang-I Cheng, Zhi-Fu Wu","doi":"10.4103/jmedsci.jmedsci_270_23","DOIUrl":"https://doi.org/10.4103/jmedsci.jmedsci_270_23","url":null,"abstract":"\u0000 Malignant hyperthermia (MH), a life-threatening complication during general anesthesia, primarily triggers hypermetabolism and skeletal muscle damage. The common MH signs include elevated body temperature, tachycardia, hypercapnia, muscle rigidity, rhabdomyolysis, hyperkalemia, and metabolic acidosis. However, MH-related skin lesions are rarely documented. Here, we present a case of a 3-year-old patient experiencing self-resolving skin rash during an MH episode. A healthy 3-year-old girl underwent strabismus surgery under general anesthesia, displaying the MH episode during the procedure. The significant vital signs included hypercapnia, tachycardia, and hyperthermia, peaking 120 min postinduction. Prompt measures, including sevoflurane discontinuation, hydration, cooling, and alternative anesthesia, swiftly stabilized the patient. Intriguingly, an hour later, an isolated skin rash emerged on the right calf and toes, which gradually resolved without intervention. Postoperative examinations revealed no adverse effects. Despite its rarity, the occurrence of MH-associated skin rashes emphasizes the need for vigilance, especially in pediatric strabismus surgeries, despite minimal documented incidents. In summary, our case highlights the self-limiting nature of MH-related skin rash, occurring post-MH resolution. Its causative mechanisms warrant further investigation. Proactive avoidance of MH trigger agents remains crucial for optimal care during pediatric strabismus surgeries.","PeriodicalId":16486,"journal":{"name":"Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140711104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DELINEATION OF HEMATOLOGICAL CHANGES OCCURRING IN STORED CITRATE PHOSPHATE DEXTROSE ADENINE CPDA-1 BLOOD 描述储存的柠檬酸盐磷酸葡萄糖腺嘌呤 cpda-1 血液中发生的血液学变化

Journal of Medical Sciences Pub Date : 2024-03-07 DOI: 10.52764/jms.24.32.1.18

Muhammad Idrees, Muhammad Waqas, M. Rehman, Huma Riaz, Muhammad Ihtesham Khan, Inayatur Rahman

{"title":"DELINEATION OF HEMATOLOGICAL CHANGES OCCURRING IN STORED CITRATE PHOSPHATE DEXTROSE ADENINE CPDA-1 BLOOD","authors":"Muhammad Idrees, Muhammad Waqas, M. Rehman, Huma Riaz, Muhammad Ihtesham Khan, Inayatur Rahman","doi":"10.52764/jms.24.32.1.18","DOIUrl":"https://doi.org/10.52764/jms.24.32.1.18","url":null,"abstract":"Objectives: To study the changes in red cell indices and counts over a period of 42 days in blood stored in blood bags.\u0000Materials and Methods: This research was done in Blood Bank, Khyber Teaching Hospital, Peshawar in collaboration with the main laboratory, Khyber Teaching Hospital, Peshawar. About 450 ml of whole blood was taken from 200 donors into Citrate Phosphate Dextrose Adenine blood bags. The storage temperature for the blood bags was maintained between 2–8°C. Blood samples were collected from blood bags. At days 1 and 42, using a haematology analyser, parameters including haemoglobin, RBC count, WBC count, haematocrit, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration and platelet counts were measured. Mean and standard deviation were used for quantitative variables. Frequency and percentages were used for qualitative variables.\u0000Results: Through days 1 to 42, Haemoglobin (Hb) level decreased from 13.4gm/dl to 12.78 gm/dl, white cell count (WBC) decreased from 6.03x109/l to 2.95 x109/l, platelets count fell from 207 x109/l to 121 x109/l, neutrophils decreased from 59.6% to 23.8% while lymphocyte count increased from 28.36% to 66.3%.\u0000Conclusion: There is a decrease in haemoglobin level and white cell count over a period of 42 days of storage of blood bags. Lymphocyte counts increased during the storage duration of blood bags.","PeriodicalId":16486,"journal":{"name":"Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140259226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0