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Journal of Neuro-Ophthalmology最新文献

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Ophthalmology in the Blink of an Eye: The Light-Induced Eyelid Reflex. 眨眼中的眼科学：光诱发的眼睑反射。
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2025-04-25 DOI: 10.1097/WNO.0000000000002358
Cyrus X Colah, Nitsan Duvedan-Strier, Emma M Hartness, Randy H Kardon
{"title":"Ophthalmology in the Blink of an Eye: The Light-Induced Eyelid Reflex.","authors":"Cyrus X Colah, Nitsan Duvedan-Strier, Emma M Hartness, Randy H Kardon","doi":"10.1097/WNO.0000000000002358","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002358","url":null,"abstract":"<p><strong>Background: </strong>A video-based assessment of the light-induced eyelid reflex, termed the photic blink reflex (PBR), was quantified based on the degree of palpebral fissure (PF) narrowing as a noninvasive test of visual input. The physiology of PF narrowing in response to light intensity was compared to the pupil light reflex, measured simultaneously.</p><p><strong>Methods: </strong>Eyelid and pupil responses to flashes of white light stimulus, increasing in intensity, were video recorded in 53 subjects using a monocular hand-held device. Responses to photopic red and blue light stimuli were recorded in 5 subjects. Percent-change of PF width and pupil width from the prestimulus baseline was measured.</p><p><strong>Results: </strong>In 81% of subjects, there was significant correlation between PF narrowing and light stimulus intensity. There was no correlation between the PBR and the pupil light reflex in the same eye in normal subjects. There was no sustained postillumination PF narrowing to bright blue-light stimuli compared to the postillumination sustained pupil response that was present in response to the same stimulus.</p><p><strong>Conclusions: </strong>The photic blink reflex can be quantified with video recording of the palpebral fissure. The photic blink reflex has potential utility as an alternative to the pupil light reflex in assessing asymmetric pathologies of the afferent visual pathway, especially in eyes with pharmacologically dilated or unreactive pupils.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":"45 2","pages":"243-248"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pallid Optic Disc Edema in Nonarteritic Anterior Ischemic Optic Neuropathy. 非动脉炎性前部缺血性视神经病变的苍白视盘水肿
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2024-05-01 DOI: 10.1097/WNO.0000000000002162
Malcolm M Kates, Danielle R Isen, Michael S Vaphiades, Lanning B Kline
{"title":"Pallid Optic Disc Edema in Nonarteritic Anterior Ischemic Optic Neuropathy.","authors":"Malcolm M Kates, Danielle R Isen, Michael S Vaphiades, Lanning B Kline","doi":"10.1097/WNO.0000000000002162","DOIUrl":"10.1097/WNO.0000000000002162","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"e114-e116"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Great Conversation With Edmond J. FitzGibbon. 《与埃德蒙·j·菲茨吉本的精彩对话》
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2025-03-27 DOI: 10.1097/WNO.0000000000002339
Rachel A Calix, George T Park, Kathleen B Digre
{"title":"A Great Conversation With Edmond J. FitzGibbon.","authors":"Rachel A Calix, George T Park, Kathleen B Digre","doi":"10.1097/WNO.0000000000002339","DOIUrl":"10.1097/WNO.0000000000002339","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"e153-e159"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unilateral Hemianopia: An Uncommon Presentation of Functional Neurologic Disorder in Pediatrics. 单侧偏视：儿科功能性神经障碍的一种罕见表现。
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2024-12-26 DOI: 10.1097/WNO.0000000000002312
Javier García-Bardera, Patricia Robles-Amor, Mireia García-Bermúdez, Marco Antonio Pascual-Santiago, Blanca Domingo-Gordo
{"title":"Unilateral Hemianopia: An Uncommon Presentation of Functional Neurologic Disorder in Pediatrics.","authors":"Javier García-Bardera, Patricia Robles-Amor, Mireia García-Bermúdez, Marco Antonio Pascual-Santiago, Blanca Domingo-Gordo","doi":"10.1097/WNO.0000000000002312","DOIUrl":"10.1097/WNO.0000000000002312","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"e150-e152"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eosinophilic Granulomatosis With Polyangiitis Presenting With Neuro-Ophthalmic Manifestations. 嗜酸性肉芽肿病伴多血管炎，表现为神经眼部表现。
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2025-03-27 DOI: 10.1097/WNO.0000000000002318
Sahar Noorani, Ali Shah Tejani, Mingyi Chen, Melanie Truong-Le
{"title":"Eosinophilic Granulomatosis With Polyangiitis Presenting With Neuro-Ophthalmic Manifestations.","authors":"Sahar Noorani, Ali Shah Tejani, Mingyi Chen, Melanie Truong-Le","doi":"10.1097/WNO.0000000000002318","DOIUrl":"10.1097/WNO.0000000000002318","url":null,"abstract":"<p><strong>Abstract: </strong>A 45-year-old man reported progressively worsening vision, photophobia, and dyschromatopsia in the left eye as well as oblique binocular diplopia. His neuro-ophthalmic examination was significant for ophthalmoplegia and optic disc edema in the left eye. MRI of the brain and orbits showed enlargement and contrast enhancement of the left lateral rectus muscle, optic nerve sheath, and cavernous sinus. He was started on corticosteroids with improvement in his symptoms, examination, and imaging. However, on cessation of corticosteroids, he developed worsening symptoms. Biopsy of the left lateral rectus muscle showed reactive lymphoid infiltrates with eosinophilia and no evidence of malignancy. While off corticosteroids, a complete blood count with differential revealed peripheral eosinophilia. He was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA) and ultimately started on steroid-sparing therapy with mepolizumab. EGPA may present with primarily ocular or orbital involvement.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"231-234"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cogan Lid Twitch Sign in Aberrant Regeneration of the Third Cranial Nerve. 第三颅神经异常再生时的 Cogan 眼睑抽搐征象
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2024-05-15 DOI: 10.1097/WNO.0000000000002179
Sneha B Gajarla, Noor A Laylani, Pamela A Davila Siliezar, Andrew G Lee
{"title":"Cogan Lid Twitch Sign in Aberrant Regeneration of the Third Cranial Nerve.","authors":"Sneha B Gajarla, Noor A Laylani, Pamela A Davila Siliezar, Andrew G Lee","doi":"10.1097/WNO.0000000000002179","DOIUrl":"10.1097/WNO.0000000000002179","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"e145-e146"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140945342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Visual Impairment With Neuropsychiatric Symptoms of Dementia. 视觉障碍与痴呆症神经精神症状的关系
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2024-08-16 DOI: 10.1097/WNO.0000000000002235
Melissa Li, Ali G Hamedani
{"title":"Association of Visual Impairment With Neuropsychiatric Symptoms of Dementia.","authors":"Melissa Li, Ali G Hamedani","doi":"10.1097/WNO.0000000000002235","DOIUrl":"10.1097/WNO.0000000000002235","url":null,"abstract":"<p><strong>Background: </strong>Visual impairment is a risk factor for cognitive impairment and hallucinations in older adults, but associations with other neuropsychiatric symptoms (NPS) of dementia have not been examined.</p><p><strong>Methods: </strong>We analyzed cross-sectional data from the Aging, Demographics, and Memory Study (ADAMS), a nationally representative sample of the US population aged 70+ years. Vision was measured by self-report and using a near card. Dementia was ascertained through cognitive testing with expert consensus, and NPS were screened using the Neuropsychiatric Inventory. We used logistic regression to measure the association between visual impairment and prevalent NPS adjusting for sociodemographic factors and comorbidities. Analyses incorporated sample weights to account for the complex survey design of ADAMS.</p><p><strong>Results: </strong>Of 624 participants with dementia, 332 (53%) had self-reported visual impairment and 193 (31%) had best-corrected acuity of 20/40 or worse. In unadjusted models, self-reported visual impairment was significantly associated with hallucinations (OR 2.88; 95% CI 1.12-7.44), depression (OR 2.79; 95% CI 1.7-4.57), and agitation (OR 1.61; 95% CI 1.05-2.48). Reduced visual acuity was associated with hallucinations (OR 10.13; 95% CI 2.93-34.98), psychosis (OR 6.69, 95% CI 2.53-17.7), and mania (OR 5.92, 95% CI 1.77-19.82). However, these associations did not remain significant after covariate adjustment.</p><p><strong>Conclusions: </strong>Visual impairment was associated with hallucinations, depression, agitation, psychosis, and mania in patients with dementia, but at least some of this relationship is explained by age, comorbidities, and other factors.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"131-136"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141988184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Presentation and Neuro-Ophthalmological Features in Spinocerebellar Ataxia Type 3: A Case Report and Literature Review. 脊髓小脑共济失调 3 型的临床表现和神经眼科特征：病例报告和文献综述。
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2024-05-06 DOI: 10.1097/WNO.0000000000002172
Ali Khodor, Raul E Ruiz-Lozano, Erin Lanzo, Laurel N Vuong, Thomas R Hedges, Yosbelkys Martin-Paez
{"title":"Clinical Presentation and Neuro-Ophthalmological Features in Spinocerebellar Ataxia Type 3: A Case Report and Literature Review.","authors":"Ali Khodor, Raul E Ruiz-Lozano, Erin Lanzo, Laurel N Vuong, Thomas R Hedges, Yosbelkys Martin-Paez","doi":"10.1097/WNO.0000000000002172","DOIUrl":"10.1097/WNO.0000000000002172","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"e132-e133"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140858518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain MRI Should Be Routinely Ordered in Patients Presenting With Acute Retinal Artery Ischemia. 急性视网膜动脉缺血患者应常规进行脑MRI检查。
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2024-10-07 DOI: 10.1097/WNO.0000000000002221
Sashank Prasad, Leanne D Stunkel, Andrew G Lee, Gregory P Van Stavern
{"title":"Brain MRI Should Be Routinely Ordered in Patients Presenting With Acute Retinal Artery Ischemia.","authors":"Sashank Prasad, Leanne D Stunkel, Andrew G Lee, Gregory P Van Stavern","doi":"10.1097/WNO.0000000000002221","DOIUrl":"10.1097/WNO.0000000000002221","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"235-242"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolution of Disc Edema in Arteritic Anterior Ischemic Optic Neuropathy. 动脉炎性前部缺血性视神经病变的视盘水肿演变。
IF 2 4区 医学
Journal of Neuro-Ophthalmology Pub Date : 2025-06-01 Epub Date: 2024-05-06 DOI: 10.1097/WNO.0000000000002167
Juan D Fernandez, Daniel P Stefanko, Anthony C Arnold
{"title":"Evolution of Disc Edema in Arteritic Anterior Ischemic Optic Neuropathy.","authors":"Juan D Fernandez, Daniel P Stefanko, Anthony C Arnold","doi":"10.1097/WNO.0000000000002167","DOIUrl":"10.1097/WNO.0000000000002167","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":"253-254"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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