Aaron H Shi, Christopher R Henry, Ore-Ofe O Adesina
{"title":"Myelin Oligodendrocyte Glycoprotein Antibody Disease Presenting With Cilioretinal Artery Occlusion.","authors":"Aaron H Shi, Christopher R Henry, Ore-Ofe O Adesina","doi":"10.1097/WNO.0000000000002511","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002511","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149039274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark J Kupersmith, Wolf A Lagrèze, Jeffrey L Bennett, Louise-Laure Mariani, Céline Louapre, Leonard A Levin
{"title":"Optic Neuritis Model to Identify Potential Neuroprotective Therapy.","authors":"Mark J Kupersmith, Wolf A Lagrèze, Jeffrey L Bennett, Louise-Laure Mariani, Céline Louapre, Leonard A Levin","doi":"10.1097/WNO.0000000000002547","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002547","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amit Lejtman, Amir Rosenblatt, Nemer Sayed Ahmad, Nir Sorkin, Ainat Klein
{"title":"Digital Color Vision Testing in Optic Neuropathy: Are Smartphone Apps Ready for Clinical Use?","authors":"Amit Lejtman, Amir Rosenblatt, Nemer Sayed Ahmad, Nir Sorkin, Ainat Klein","doi":"10.1097/WNO.0000000000002525","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002525","url":null,"abstract":"<p><strong>Background: </strong>Color vision impairment is a common feature of optic neuropathy, typically assessed with the printed Ishihara booklet. Smartphone-based alternatives are increasingly used, but their diagnostic performance in optic neuropathy is incompletely established.</p><p><strong>Methods: </strong>In this prospective, single-center diagnostic study, 77 participants (42 healthy trichromats and 35 patients with unilateral optic neuropathy of various etiologies) completed 3 monocular color vision tests in a randomized order: a 17-plate Ishihara booklet, the PseudoChromatic ColorTest (PCCT) smartphone application, and the Eye Handbook (EHB) smartphone application, all administered on an iPhone 8 Plus under standardized illumination and viewing distance. The primary outcome was diagnostic accuracy (area under the receiver operating characteristic curve [AUC]); secondary outcomes were correlations of test performance with best-corrected visual acuity and visual field mean deviation and participants' test preference.</p><p><strong>Results: </strong>All 3 tests significantly differentiated healthy from optic neuropathy eyes (P < 0.001). The PCCT achieved the highest AUC (0.812), followed by the EHB (0.778) and the Ishihara booklet (0.736), with no statistically significant between-test differences. Test performance correlated significantly with visual acuity and visual field mean deviation, but not with age. Test preference differed significantly between groups (P = 0.004), with healthy participants favoring app-based testing.</p><p><strong>Conclusions: </strong>Smartphone-based color vision tests demonstrated overall discriminatory performance similar to that of the printed Ishihara booklet for detecting optic neuropathy, with the PCCT achieving the highest diagnostic accuracy. They may serve as practical screening tools, particularly in tele-ophthalmology and resource-limited settings; independent validation of each application is required before clinical implementation.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aileen G MacLachlan, Cameron M Carpenter, Natalie K Modersitzki, Alison V Crum, Kathleen B Digre, Bradley J Katz, Sravanthi Vegunta, Judith E A Warner, Theresa M Long, Meagan D Seay
{"title":"Use of a Virtual Reality Visual Field Device to Improve Quality of Care in the Emergency Department and Inpatient Setting.","authors":"Aileen G MacLachlan, Cameron M Carpenter, Natalie K Modersitzki, Alison V Crum, Kathleen B Digre, Bradley J Katz, Sravanthi Vegunta, Judith E A Warner, Theresa M Long, Meagan D Seay","doi":"10.1097/WNO.0000000000002526","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002526","url":null,"abstract":"<p><strong>Background: </strong>Automated visual field testing is an essential diagnostic and disease monitoring tool for many neuro-ophthalmic disorders. Most commonly, automated devices are stationary and located in ophthalmology clinics. Thus, formal visual field testing has been limited in the hospital setting until recent availability of virtual reality visual field testing. In this study, we report our experience with the use of a virtual visual field (VVF) device in the Emergency Department (ED) and inpatient hospital settings.</p><p><strong>Methods: </strong>We performed a retrospective chart review of our use of a VVF device in the ED and inpatient hospital setting from February 2020 to September 2022. We report our experience and the impact on patient care with use of the VVF device.</p><p><strong>Results: </strong>One hundred fifty patients (aged 10-85 years) and 162 visual field encounters were identified. Patients were most commonly located on the regular hospital ward (51%), followed by the intensive care unit (28%), and ED (21%). The VVF prevented the need for a trip to the outpatient ophthalmology clinic in 100% of encounters of patients with vision-threatening papilledema. Use of the VVF provided a more detailed, baseline examination at bedside in 61% of all encounters. A bedside pre- and postoperative visual field assessment was achieved in 14% of encounters. The VVF changed management in 70% of encounters.</p><p><strong>Conclusions: </strong>In our experience, use of the VVF has improved the quality of care for inpatients with neuro-ophthalmic conditions. A significant impact of the VVF was increased safety by preventing the need to transport patients to the outpatient setting for visual field monitoring, especially patients with vision-threatening papilledema and lumbar drains. The VVF made formal visual testing available to patients with mobility restrictions and patients undergoing neurosurgical procedures. Owing to improvement in quality of patient care, the VVF analyzer has become a mainstay of the examination of patients in the ED and hospital.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply: Anemia and Pseudotumor Cerebri: Absence of a Population-Level Association Does Not Negate Individual-Level Causation.","authors":"Alison B Gibbons, Ximin Li, Amanda D Henderson","doi":"10.1097/WNO.0000000000002532","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002532","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victoria Dezard, Heather McDonald, Edward Margolin
{"title":"Bilateral Vitritis and Optic Disc Edema as the Presenting Manifestation of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy.","authors":"Victoria Dezard, Heather McDonald, Edward Margolin","doi":"10.1097/WNO.0000000000002528","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002528","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment: Anemia and Pseudotumor Cerebri: Absence of a Population-Level Association Does Not Negate Individual-Level Causation.","authors":"Bradley J Katz, Nancy J Newman, Valérie Biousse","doi":"10.1097/WNO.0000000000002533","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002533","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Labella Alvarez, Gabriele Berman, Michael Lowe, Pichaya Kulniwatcharoen, Susan P Mollan
{"title":"Reply: Optic Nerve Sheath Compartmentation as a Mechanism for Idiopathic Intracranial Hypertension Without Papilledema.","authors":"Fernando Labella Alvarez, Gabriele Berman, Michael Lowe, Pichaya Kulniwatcharoen, Susan P Mollan","doi":"10.1097/WNO.0000000000002541","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002541","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"NANOSNEWS: European Neuro-Ophthalmology Society Held Its Meeting in Milan, Italy, June 3-6, 2026.","authors":"Judith E A Warner, Kathleen B Digre","doi":"10.1097/WNO.0000000000002534","DOIUrl":"10.1097/WNO.0000000000002534","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment: Progression of Vitreous Detachment Leading to Exacerbation of Visual Field Loss in Acute Nonarteritic Anterior Ischemic Optic Neuropathy.","authors":"M Tariq Bhatti","doi":"10.1097/WNO.0000000000002548","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002548","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}