Lema H Noubani, Lena A Hummel, Mohammad Pakravan, Chaow Charoenkijkajorn, Peter W Mortensen, Andrew G Lee
{"title":"Delayed Diagnosis of Thymoma in Ocular Myasthenia Gravis.","authors":"Lema H Noubani, Lena A Hummel, Mohammad Pakravan, Chaow Charoenkijkajorn, Peter W Mortensen, Andrew G Lee","doi":"10.1097/WNO.0000000000001846","DOIUrl":"10.1097/WNO.0000000000001846","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44098213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
George Jiao, Carolyn Sommer, Ravneet S Rai, Sylvia R Kodsi, Hal R Schwartzstein, David H Abramson, Carolyn Fein-Levy
{"title":"Markedly Asymmetric Opsoclonus as the Initial Presentation of Trilateral Retinoblastoma and an Undifferentiated Metastatic Tumor.","authors":"George Jiao, Carolyn Sommer, Ravneet S Rai, Sylvia R Kodsi, Hal R Schwartzstein, David H Abramson, Carolyn Fein-Levy","doi":"10.1097/WNO.0000000000001892","DOIUrl":"10.1097/WNO.0000000000001892","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9888609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clement C Anozie, Pamela A Davila Siliezar, Noor A Laylani, Andrew G Lee
{"title":"Idiopathic Intracranial Hypertension in a Patient With Obesity Hypoventilation Syndrome and Obstructive Sleep Apnea.","authors":"Clement C Anozie, Pamela A Davila Siliezar, Noor A Laylani, Andrew G Lee","doi":"10.1097/WNO.0000000000001953","DOIUrl":"10.1097/WNO.0000000000001953","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9899441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachel C Kenney, Tim W Requarth, Alani I Jack, Sara W Hyman, Steven L Galetta, Scott N Grossman
{"title":"AI in Neuro-Ophthalmology: Current Practice and Future Opportunities.","authors":"Rachel C Kenney, Tim W Requarth, Alani I Jack, Sara W Hyman, Steven L Galetta, Scott N Grossman","doi":"10.1097/WNO.0000000000002205","DOIUrl":"10.1097/WNO.0000000000002205","url":null,"abstract":"<p><strong>Background: </strong>Neuro-ophthalmology frequently requires a complex and multi-faceted clinical assessment supported by sophisticated imaging techniques in order to assess disease status. The current approach to diagnosis requires substantial expertise and time. The emergence of AI has brought forth innovative solutions to streamline and enhance this diagnostic process, which is especially valuable given the shortage of neuro-ophthalmologists. Machine learning algorithms, in particular, have demonstrated significant potential in interpreting imaging data, identifying subtle patterns, and aiding clinicians in making more accurate and timely diagnosis while also supplementing nonspecialist evaluations of neuro-ophthalmic disease.</p><p><strong>Evidence acquisition: </strong>Electronic searches of published literature were conducted using PubMed and Google Scholar. A comprehensive search of the following terms was conducted within the Journal of Neuro-Ophthalmology: AI, artificial intelligence, machine learning, deep learning, natural language processing, computer vision, large language models, and generative AI.</p><p><strong>Results: </strong>This review aims to provide a comprehensive overview of the evolving landscape of AI applications in neuro-ophthalmology. It will delve into the diverse applications of AI, optical coherence tomography (OCT), and fundus photography to the development of predictive models for disease progression. Additionally, the review will explore the integration of generative AI into neuro-ophthalmic education and clinical practice.</p><p><strong>Conclusions: </strong>We review the current state of AI in neuro-ophthalmology and its potentially transformative impact. The inclusion of AI in neuro-ophthalmic practice and research not only holds promise for improving diagnostic accuracy but also opens avenues for novel therapeutic interventions. We emphasize its potential to improve access to scarce subspecialty resources while examining the current challenges associated with the integration of AI into clinical practice and research.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141534650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amir R Vosoughi, Natalie Brossard Barbosa, Jonathan Micieli, Edward Margolin
{"title":"Unilateral Pendular Nystagmus in Multiple Sclerosis: A Case Series.","authors":"Amir R Vosoughi, Natalie Brossard Barbosa, Jonathan Micieli, Edward Margolin","doi":"10.1097/WNO.0000000000001944","DOIUrl":"10.1097/WNO.0000000000001944","url":null,"abstract":"<p><strong>Background: </strong>Acquired pendular nystagmus is most often seen in patients with demyelinating disease. Although it is often bilateral, rare cases may be monocular. There is paucity of data on the spectrum of clinical presentation, underlying mechanism, and response to treatment in patients with monocular pendular nystagmus.</p><p><strong>Methods: </strong>Retrospective case series of patients with monocular pendular nystagmus seen in 2 tertiary neuro-ophthalmology clinics between January 2019 and June 2022. All patients underwent a complete neuro-ophthalmological assessment and MRI.</p><p><strong>Results: </strong>We describe 5 patients (3 women) aged 31-49 with monocular pendular nystagmus. All had a diagnosis of multiple sclerosis. Three patients had horizontal and 2 had vertical pendular nystagmus. The Snellen visual acuity in the eye with pendular nystagmus varied from 20/20 to 20/200. Two patients were asymptomatic and 3 suffered visually debilitating oscillopsia. Treatment response was available for 2 patients, both of which responded well to treatment with memantine. The pendular nystagmus was observed in the eye with worse visual acuity in 4 of 5 cases (80%). Three patients had bilateral pontine lesions, and 2 had unilateral pontine lesion ipsilateral to the side of nystagmus.</p><p><strong>Conclusions: </strong>Monocular pendular nystagmus in adults is seen most often in patients with multiple sclerosis. Asymmetry in brainstem lesions and afferent visual input may be the culprit. Treatment with memantine may result in significant improvement in symptomatic patients.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9931848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optic Nerve Enhancement in the Setting of Wernicke Encephalopathy.","authors":"Amy E Pohodich, Julie Falardeau","doi":"10.1097/WNO.0000000000001910","DOIUrl":"10.1097/WNO.0000000000001910","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9639928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minh N L Nguyen, Anthony J Fok, Tsz Yan C Kho, Shivanand J Sheth
{"title":"Vertical Ocular Misalignment Associated With an Anomalous Extraocular Band.","authors":"Minh N L Nguyen, Anthony J Fok, Tsz Yan C Kho, Shivanand J Sheth","doi":"10.1097/WNO.0000000000001929","DOIUrl":"10.1097/WNO.0000000000001929","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9816970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Christian Berry, Neal Rangu, Ben J Harvey, James C O'Brien
{"title":"Case of an Inadvertent Filtering Bleb in Marfan Syndrome Resulting in Clinical Hypotony.","authors":"J Christian Berry, Neal Rangu, Ben J Harvey, James C O'Brien","doi":"10.1097/WNO.0000000000001927","DOIUrl":"10.1097/WNO.0000000000001927","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9730319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akash Gupta, Mohammad Pakravan, Chaow Charoenkijkajorn, Andrew G Lee
{"title":"Strabismus Associated With the Good Syndrome (Immunodeficiency and Thymoma).","authors":"Akash Gupta, Mohammad Pakravan, Chaow Charoenkijkajorn, Andrew G Lee","doi":"10.1097/WNO.0000000000001854","DOIUrl":"10.1097/WNO.0000000000001854","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9443047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}