Journal of Molecular Structure最新文献

{"title":"Synthesis and characterization of thermal properties of poly(p-cumylphenyl methacrylate-co-methoxyethyl methacrylate) copolymers","authors":"E. Parthiban ,&nbsp;S. Sudarsan ,&nbsp;A. Charles ,&nbsp;S. Mohan ,&nbsp;A. Kumar ,&nbsp;A. Kistan","doi":"10.1016/j.molstruc.2024.140890","DOIUrl":"10.1016/j.molstruc.2024.140890","url":null,"abstract":"<div><div>The poly(p-cumylphenyl methacrylate-co-methoxyethyl methacrylate) copolymers has been fabricated in a simple way. The p-cumylphenyl methacrylate and methoxy methacrylate were polymerized by free radical mechanism using benzoyl peroxide as an initiator. The synthesized copolymers were confirmed by Fourier transform infrared spectroscopy (FTIR), proton nuclear magnetic resonance (¹H NMR) and carbon nuclear magnetic resonance (¹³C NMR) spectral techniques. The heat durability of copolymers has been investigated by Thermogravimetric analysis (TGA), derivative thermogravimetry, and differential thermal analysis (DTA). The glass transition temperature (Tg) of copolymer was carried out using differential scanning calorimetry (DSC). The scanning electron microscopy (SEM) was utilized to observe the surface texture and morphology roughness of copolymers. The obtained copolymers have possess an excellent coating property, anti-corrosive property, and optical property. Hence, these can be utilize in different way like solar, sensors, polymer conductivity, battery electrolytes, nanotechnology, viscosity, and biomedical.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140890"},"PeriodicalIF":4.0,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142748192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of pyridin-3-yl-1,3,4-oxadiazole and 5-p-tolyl-1,3,4-oxadiazole derivatives and their evaluation as antihyperglycemic agents, AChE and BuChE inhibitors, and antioxidants","authors":"Bibi Fatima ,&nbsp;Faiza Saleem ,&nbsp;Uzma Salar ,&nbsp;Sridevi Chigurupati ,&nbsp;Shatha Ghazi Felemban ,&nbsp;Sreenath Konanki ,&nbsp;Zaheer Ul-Haq ,&nbsp;Sajda Ashraf ,&nbsp;Muhammad Taha ,&nbsp;Khalid Mohammed Khan","doi":"10.1016/j.molstruc.2024.140856","DOIUrl":"10.1016/j.molstruc.2024.140856","url":null,"abstract":"<div><div>Thirty oxadiazole derivatives <strong>1–30</strong> were synthesized <em>via</em> nucleophilic substitution reactions between 1,3,4-oxadiazole-2-thiol and benzyl/phenacyl halides. The structural elucidation of compounds was done by EI-MS, HREI-MS, ^1HNMR , and ^13CNMR . The compounds were divided into three categories based on their substitution patterns. Among thirty synthetic compounds, four compounds, <strong>13, 14, 15</strong>, and <strong>19</strong>, were found to be new. The inhibitory activities of compounds were evaluated against <em>α</em>-amylase, <em>α</em>-glucosidase, AChE, and BuChE <em>in vitro</em>. Compound <strong>8</strong> (IC₅₀ = 20.71 ± 0.16; 19.04 ± 0.52 <em>µ</em>M), possessing a 2-chloro-4-fluoro benzyl ring, demonstrated the highest antihyperglycemic activity among these oxadiazoles. Despite showing slightly lower activity than the standard acarbose (IC₅₀ = 13.19 ± 0.26; 16.28 ± 0.24 <em>µ</em>M), it can be a potential candidate for further exploration as an antihyperglycemic agent. Compound <strong>16</strong> (IC₅₀ = 7.33 ± 0.02; 9.5 ± 0.16 <em>µ</em>M) containing an unsubstituted phenacyl group demonstrated the highest inhibitory potential against AChE and BChE enzymes as compared to the standard donepezil with IC₅₀ values of 2.05 ± 0.12 <em>µ</em>M and 4.02 ± 0.06 <em>µ</em>M. Molecular docking analysis revealed favorable interactions, including hydrogen bonding, hydrophobic, and <em>π-π</em> stacking interactions between the compounds and the target proteins. Additionally, the antioxidant potential of the compounds was assessed using DPPH and ABTS radical scavenging assays, and compounds revealed significant activities. The study provides valuable insights into the structure-activity relationship of these compounds, which could guide future drug design efforts for more potent enzyme inhibitors.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140856"},"PeriodicalIF":4.0,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142748203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and structural characterization BODIPY-based compounds for fluorescence sensing of β-amyloid aggregates","authors":"Hilal Kırpık ,&nbsp;Robert B.P. Elmes ,&nbsp;Koray Sayin ,&nbsp;Muhammet Kose","doi":"10.1016/j.molstruc.2024.140848","DOIUrl":"10.1016/j.molstruc.2024.140848","url":null,"abstract":"<div><div>Alzheimer's disease (AD) is a neurodegenerative disorder associated with aging. According to the amyloid cascade hypothesis, the aggregation and accumulation of β-amyloid (Aβ) peptides in the brain as Aβ plaques is a critical process in the pathogenesis of AD. Among the existing diagnosis methods, fluorescence detection of β-amyloid (Aβ) has emerged as an alternative method due to its advantages such as real-time detection, low cost, not exposed to radiation, and high resolution for early diagnosis of Alzheimer's disease (AD). In this study, we designed and synthesized BODIPY-based compounds (<strong>BODIPY-3, BODIPY-4</strong> and <strong>BODIPY-5</strong>) for the fluorescence detection of Aβ aggregates. In the fluorescence studies for detecting Aβ, BODIPY-5 with the squaric acid ester unit at the meso position of the BODIPY core showed a promising effect with an 11.7 μM Kd value.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140848"},"PeriodicalIF":4.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142720945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication of CuS-MoO3 nanocomposite for high-performance photocatalysis and biosensing","authors":"E. Vinay Kumar ,&nbsp;T.L. Soundarya ,&nbsp;B.E. Kumara Swamy ,&nbsp;Anitha ,&nbsp;G. Nagaraju","doi":"10.1016/j.molstruc.2024.140823","DOIUrl":"10.1016/j.molstruc.2024.140823","url":null,"abstract":"<div><div>The design and development of highly efficient nanostructure materials for photocatalytic and electrochemical applications is very necessary. In this study, CuS-MoO₃ nanocomposite (NCs) was fabricated using a simple wet impregnation process and the photodegradation potential for 8 major hazardous dyes and electrochemical sensing of Dopamine was investigated. X-ray diffraction (XRD), Fourier transform - Infrared spectroscopy (FTIR), UV-Vis spectroscopy (UV-Vis), Photoluminescence spectroscopy (PL), Scanning Electron Microscopy (SEM), Energy-dispersive X-ray spectroscopy (EDX) and Transmission Electron Microscopy (TEM) were employed for characterization. Fabricated NCs are made up of CuS in the hexagonal phase and MoO₃ in the orthorhombic phase, both of which react to UV light. Optical and electrochemical impedance spectroscopy (EIS) results show that improved photocatalytic performance is related to increased UV light spectrum sensitivity, inhibited charge carrier recombination, and decreased band gap energy in the NCs. Experimental findings showed that CuS-MoO₃ (CMS) NCs had substantially more photocatalytic degradation activity than pure MoO₃ and CuS nanoparticles (NPs). The prepared CMS NCs were then used for electrochemical analysis of Dopamine (DA). Electroanalytical results showed that the CMS NCs had enhanced electrochemical activity towards DA. The constructed sensor has a limit of detection of (6.61 µM) and proved that it is capable of being a sensor.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140823"},"PeriodicalIF":4.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural development of curcumin: A natural product arsenal for diverse therapeutic targets- seizing opportunities through serendipity and rational design","authors":"Mahmood Ahmed ,&nbsp;Sehar Basheer ,&nbsp;Mohammed H. AL Mughram ,&nbsp;Dure Najaf Iqbal ,&nbsp;Shaista Qamar ,&nbsp;Ahmad Saeed ,&nbsp;Rida Batool ,&nbsp;Mudassar Sanaullah ,&nbsp;Hussain Raza ,&nbsp;Riaz Hussain","doi":"10.1016/j.molstruc.2024.140815","DOIUrl":"10.1016/j.molstruc.2024.140815","url":null,"abstract":"<div><div>Curcumin, a polyphenolic compound found in turmeric, has demonstrated various therapeutic properties such as anti-inflammatory, antioxidant, and anti-cancer effects. However, its clinical application is limited by its poor bioavailability, which stems from its low solubility, rapid metabolism, and quick systemic elimination. Modifications in the chemical structure of curcumin have been employed to improve its pharmacokinetic properties. Incorporating various functional groups into the curcumin molecule can significantly impact its activity. Creating hybrid molecules by combining curcumin with other bioactive compounds can result in synergistic effects. The structural development of curcumin aims to enhance its therapeutic efficacy by improving its bioavailability, stability, and specific activity against various diseases. These new molecules could offer improved potency and target specific therapeutic areas more effectively. This review explores the serendipitous discoveries and rational design approaches that have contributed to curcumin's development as a potent therapeutic agent which can unlock a broader spectrum of therapeutic applications.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140815"},"PeriodicalIF":4.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142748198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel silver(I) two-dimensional coordination polymer of thiophosphoric triamide ligand with two different coordination modes: Experimental, theoretical and molecular docking study","authors":"Zeinab Gholamrezaei,&nbsp;Atekeh Tarahhomi","doi":"10.1016/j.molstruc.2024.140843","DOIUrl":"10.1016/j.molstruc.2024.140843","url":null,"abstract":"<div><div>Novel thiophosphoric triamide (S)P[NC₄H₈O]₃ (PS, compound <strong>1</strong>) and silver(I) two-dimensional coordination polymer derived from it ([Ag^(I)₃(PS)₂(NO₃)₃]_n, <strong>2</strong>) as the first coordination polymer derived form a <em>S</em>-donor mono-dentate thiophosphoric triamide ligand were synthesized and structurally studied. The structures crystallize in the monoclinic system with space group <em>P</em>2₁/<em>n</em> for PS and <em>C</em>2<em>/c</em> for Ag^(I) complex. The asymmetric unit consists of one complete molecule for <strong>1</strong> and of two Ag^(I) ion, one PS ligand, one nitrate anion as well as one-half of a nitrate anion for <strong>2</strong>. The infinite array of [Ag^(I)₃(PS)₂(NO₃)₃]_n is composed of the two different coordination modes of two- and five-coordinate Ag^(I) with metal center environment of a near linear of Ag(S)₂ and a highly distorted square pyramidal of Ag(O)₄(S). Intermolecular interactions are addressed by Hirshfeld surface (HS) analysis showing C—H…O hydrogen bonds (in <strong>1</strong> and <strong>2</strong>) and Ag…O contacts (in <strong>2</strong>) as dominant interactions to form the crystal packing cohesion. A molecular docking simulation was performed to study interactions and binding modes between <strong>1</strong> and <strong>2</strong> with target proteins of SARS-CoV-2 and Monkeypox showing an acceptable interaction tendency with maximum binding affinities of around −6 (for CoV-2) and −8 (for Mpox) kcal/mol for Ag^(I) coordination polymer <strong>2</strong>. For a further investigation of the Ag^(I)—O/S contacts, theoretical QTAIM and NBO calculations were run suggesting that these contacts are closed-shell (mainly ionic) in nature.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140843"},"PeriodicalIF":4.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142748157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive analysis of a novel antimony-based organic-inorganic hybrid material: structural, vibrational, and hirshfeld surface investigations of (C8H14N2)[SbCl5]","authors":"Amin Alibi ,&nbsp;Nour Elleuch ,&nbsp;Sergiu Shova ,&nbsp;Mohamed Boujelbene","doi":"10.1016/j.molstruc.2024.140857","DOIUrl":"10.1016/j.molstruc.2024.140857","url":null,"abstract":"<div><div>The novel organic-inorganic hybrid compound, N,N’-di(4-ethyl aminomethyl)pyridinium pentachloride antimonate (III), designated as (C₈H₁₄N₂)[SbCl₅], was synthesized and crystallized through a slow evaporation technique to facilitate comprehensive analysis of its crystal structure and molecular composition. Single-crystal X-ray diffraction revealed that this supramolecular compound crystallizes in the centrosymmetric space group P21/n within the orthorhombic system. The unit cell parameters were determined as follows: a = 10.8365(3) Å, b = 11.8067(3) Å, c = 12.0281(3) Å, and β = 106.920(3)°. The crystal structure was solved using direct methods and refined via the least squares technique, yielding final values of R₁ = 0.0218 and wR₂ = 0.0444. To further confirm the structure's stability and coherence, we investigated various interaction types and the contribution of hydrogen bonding to the overall molecular interactions through Hirshfeld surface analysis. This analysis, complemented by 2D fingerprint plots, highlighted the predominance of Cl⋯H/H⋯Cl interactions, which accounted for 59.1 % of the total interactions. Additionally, the study of crystal voids indicated that 7.1 % of the unit cell volume is composed of void space, contributing to the mechanical strength of the compound. Furthermore, FTIR spectroscopy and Raman scattering were utilized to identify the functional and molecular groups within the crystal by analyzing their vibrational modes.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140857"},"PeriodicalIF":4.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical investigation of Dy3+/ Eu3+ co-activated K2NaAlF6 fluorophosphor for color tunable lighting system: Structural analysis and warm light generation","authors":"A.V. Bharati ,&nbsp;Balvinder Talwar ,&nbsp;Sanjogta Meshram","doi":"10.1016/j.molstruc.2024.140831","DOIUrl":"10.1016/j.molstruc.2024.140831","url":null,"abstract":"<div><div>Nowadays, research is mostly focused on developing luminous materials. Specifically, compounds based on inorganic phosphorus have found widespread use in a variety of applications, like radiation dosimetry, field emission displays (FEDs), cathode ray tubes (CRTs), lamp industries, and white light emitting diodes (WLEDs). In order to achieve white light emission, we successfully synthesized single-host K₂NaAlF₆ co-doped with Dy³⁺/Eu³⁺ in this study utilizing the pechini sol-gel approach. Under UV light, the synthesized samples' luminescence characteristics were examined. XRD analysis verified K₂NaAlF₆'s phase purity. The phosphor materials have a tendency to aggregate, as seen by SEM pictures. The K₂NaAlF₆:Dy³⁺ doped phosphors showed good excitation at 349 nm in photoluminescence (PL) experiments, with strong emission bands at 489 nm (blue) and 576 nm (yellow). Strong orange emissions were seen for K₂NaAlF₆: Eu³⁺ doped phosphors at 595 nm and 614 nm, which correspond to the ⁵D₀→⁷F₁ and ⁵D₀→⁷F₂ transitions in Eu³⁺ ions. When these rare earths were co-doped, intense red, yellow, and blue emissions were produced. The Commission Internationale de l'Eclairage (CIE) coordinates were used to calculate the colour characteristics of the luminous produced samples. Consequently, these results imply that Dy³⁺/Eu³⁺ co-doped K₂NaAlF₆ phosphors, when stimulated by UV LEDs, could be appropriate for creating reddish-orange and warm white lighting systems.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140831"},"PeriodicalIF":4.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cinnamaldehyde-based hydrazone schiff bases as inhibitors of pepsin and trypsin: A comparative study","authors":"Chanchal Vashisth ,&nbsp;Nitin Kumar Verma ,&nbsp;Neera Raghav","doi":"10.1016/j.molstruc.2024.140845","DOIUrl":"10.1016/j.molstruc.2024.140845","url":null,"abstract":"<div><div>Selective targeting by a therapeutic agent is of significant importance in the development of a medicinally important compound. In the present work, we report preferential inhibition of pepsin by cinnamaldehyde-based hydrazone schiff bases over trypsin, keeping in view the significance of the development of protease inhibitors. The results revealed the significance of these hydrazone-hybrid molecules of cinnamaldehyde in inhibiting pepsin and trypsin at respective concentrations of 1 × 10⁻⁸ M and 1 × 10⁻⁷ M Compounds 2 and 7 demonstrated the highest inhibition, with approximately 79 % and 80 % at the respective concentrations for trypsin and pepsin. The respective IC₅₀ values were found to be 4.4 nM and 0.76 nM. The findings from the <em>in vitro</em> experiments were authenticated by <em>in silico</em> studies.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140845"},"PeriodicalIF":4.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142748197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"15N NMR spectroscopy in the investigation of the structure of enaminones","authors":"Marta Bugaj-Zarębska,&nbsp;Jarosław Jaźwiński","doi":"10.1016/j.molstruc.2024.140846","DOIUrl":"10.1016/j.molstruc.2024.140846","url":null,"abstract":"<div><div>Geometry investigation of compounds which can exist in the form of different, mutually interconverting stereoisomers/rotamers is still the subject of interest. NMR spectroscopy is very helpful in such structural studies. Especially ¹⁵N NMR spectroscopy, which is known to be sensitive to structural changes in remote parts of molecules, is expected to be useful for the examination of n,π-conjugated systems as enaminones. In the present work, ¹⁵N NMR spectroscopy was applied to the study series of enaminones of type R¹R²N-CH=CH-C(O)H and R¹R²N-CH=CH-C(O)Me. Measurements at low temperatures (-60 and -90°C) in various solvents such as methanol-<em>d₄</em>, acetone-<em>d₆</em>, methylene chloride-<em>d₂</em>, and chloroform-<em>d</em>, using various compound concentrations, enabled the observation of signals of individual rotamers and allowed us to find relationships between the ¹⁵N chemical shifts and the structure of compounds. The experimental data was supplemented by DFT/6-311++G(2d,p) calculations of the shielding constants and the indirect spin-spin coupling constants. Topological analysis using Atom-In-Molecule approach revealed, in addition to the presence of intramolecular NH^...O hydrogen bonds in some rotamers, also non-covalent interactions of NH^...HCH₂, =O^...H₃C, and H₂CH^...HCH₂ in <em>Z</em> rotamers. Theoretical spin-spin indirect coupling constants including Ramsey paramagnetic spin-orbit and diamagnetic spin-orbit contributions turned out to be a convenient descriptor of noncovalent interactions.</div></div>","PeriodicalId":16414,"journal":{"name":"Journal of Molecular Structure","volume":"1324 ","pages":"Article 140846"},"PeriodicalIF":4.0,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142748200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}