Journal of Medicine and Life最新文献_第2页

The dissection-based identification of the preaortic sympathetic plexus formation, anatomical relations, and clinical applications. 主动脉前交感神经丛的解剖鉴定、解剖关系及临床应用。

Journal of Medicine and Life Pub Date : 2025-04-01 DOI: 10.25122/jml-2025-0069

Mihaly Enyedi, Georgian-Theodor Badea, Radu-Tudor Ion, Daniela Elena Gheoca Mutu, Stefan Oprea, Zoran Florin Filipoiu

{"title":"The dissection-based identification of the preaortic sympathetic plexus formation, anatomical relations, and clinical applications.","authors":"Mihaly Enyedi, Georgian-Theodor Badea, Radu-Tudor Ion, Daniela Elena Gheoca Mutu, Stefan Oprea, Zoran Florin Filipoiu","doi":"10.25122/jml-2025-0069","DOIUrl":"10.25122/jml-2025-0069","url":null,"abstract":"The abdominal sympathetic nervous system provides sympathetic innervation to the abdominal organs and gonads. This system is part of an extensive neural network that extends from the base of the skull to the pelvis. The preaortic (or prevertebral) plexus is a key component of the abdominal sympathetic system and is represented by a variable nervous network located anterior to the abdominal aorta. The aim of our study was to identify all these sympathetic structures and describe the formation and relationships of the preaortic plexus. We examined five cadavers (aged 66-71) with no medical or surgical history, preserved in 9% formalin at the Anatomy Department from Carol Davila University. Regional dissections were performed in successive planes, highlighting the major abdominal plexuses, the lumbar splanchnic nerves, and the associated network of neural connections that contribute to the preaortic plexus. The plexus is formed by efferent fibers from the celiac and aortico-renal ganglia, as well as from the three lumbar splanchnic nerves. The lumbar splanchnic nerves originate in the paravertebral sympathetic chains. We identified all these sympathetic structures and described the formation and anatomical relationships of the plexus. The nerve fibers of various origins form a longitudinally oriented network located anterolateral to the abdominal aorta. The lower part of this network continues into the superior hypogastric plexus. This neural network is delicate, complex, and variable, making it challenging to identify anatomically and surgically. Situated deeply in the retroperitoneal space, it is prone to accidental injuries during surgery in this compartment.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 4","pages":"351-356"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12094316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of external environment on pulmonary development - a morphological evaluation of pulmonary tissue in preterm infants. 外部环境对肺部发育的影响——早产儿肺组织形态学评价。

Journal of Medicine and Life Pub Date : 2025-04-01 DOI: 10.25122/jml-2025-0045

Raluca Chirculescu, Paul Cristian Balanescu, Gheorghe Peltecu

{"title":"The impact of external environment on pulmonary development - a morphological evaluation of pulmonary tissue in preterm infants.","authors":"Raluca Chirculescu, Paul Cristian Balanescu, Gheorghe Peltecu","doi":"10.25122/jml-2025-0045","DOIUrl":"10.25122/jml-2025-0045","url":null,"abstract":"Preterm birth disrupts the natural progression of pulmonary development, which can trigger functional and morphological consequences that may lead to death or the development of a chronic lung disease. The objective of this research was to evaluate the pulmonary morphological characteristics in 67 preterm neonates who had survived for a minimum of 24 hours. All evaluations were carried out on paraffin-embedded lung tissue, sliced at 5 micrometers, and stained with a standard hematoxylin-eosin stain. From each case, photomicrographs of one square millimeter were assessed, and the quantity of alveoli, the diameter of the alveoli, the thickness of the alveolar septum, and the total thickness of the arteriolar and venular walls were measured. The research findings revealed that prolonged oxygen therapy has an impact on the density of alveoli per square millimeter in premature infants, regardless of their gestational age at birth. Additionally, neonates with lobar lung abnormalities exhibit a reduced number of alveoli per square millimeter. Moreover, preterm neonates delivered at extreme gestational ages demonstrated a notably reduced alveolar diameter compared to those born at more advanced gestational ages, and infants who developed bronchopulmonary dysplasia may exhibit increased alveolar septal thickness compared to other newborns.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 4","pages":"338-343"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12094313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors and predisposing conditions for amniotic fluid embolism: a comprehensive review. 羊水栓塞的危险因素和易感条件：全面回顾。

Journal of Medicine and Life Pub Date : 2025-04-01 DOI: 10.25122/jml-2024-0406

Jumana Hussain Timraz, Ruqayyah Ali Ahmed, Nada Yasser Metwali, Zenab Javed, Shahd Abdelazim, Raabeah Farhan, Faten Ahmad Yaseen, Hossam Abdelfatah Mansour

{"title":"Risk factors and predisposing conditions for amniotic fluid embolism: a comprehensive review.","authors":"Jumana Hussain Timraz, Ruqayyah Ali Ahmed, Nada Yasser Metwali, Zenab Javed, Shahd Abdelazim, Raabeah Farhan, Faten Ahmad Yaseen, Hossam Abdelfatah Mansour","doi":"10.25122/jml-2024-0406","DOIUrl":"10.25122/jml-2024-0406","url":null,"abstract":"Amniotic fluid embolism (AFE) is a rare, yet life-threatening obstetric emergency characterised by sudden collapse of the mother due to circulatory and respiratory failure, often accompanied by coagulopathy. It accounts for a significant proportion of peripartum cardiac arrests and maternal deaths, with an incidence of 2-8 per 100,000 deliveries. The specific pathophysiology behind AFE remains unclear. However, one hypothesis states that amniotic fluid or fetal debris enters the maternal circulation, triggering a severe inflammatory and immunologic response. Diagnosis of AFE is primarily clinical as it relies on exclusion due to the unavailability of any definitive diagnostic test. Risk factors include caesarean delivery, multiple pregnancies, advanced maternal age, and pre-existing health conditions or comorbidities. Effective management centres on early recognition, aggressive, urgent supportive measures, and resuscitation. Advanced therapeutic options, such as veno-arterial extracorporeal membrane oxygenation (VA-ECMO), have shown potential in severe cases. Despite medical advancements in supportive care, which have led to reduced mortality rates, AFE remains highly unpredictable, carrying a significant risk of maternal and fetal mortality and morbidity. Survivors are often faced with long-term complications such as neurological deficits and cardiac problems. This comprehensive review aims to improve clinicians' awareness of AFE, summarize its risk factors, and provide an overview of the current strategies for early recognition and management, emphasizing recent advancements and the need for continued research in this critical area.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 4","pages":"277-284"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12094319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Horizons in Neuroscience: The Summer School of Brain Mapping and Stimulation Techniques. 神经科学的新视野：大脑测绘和刺激技术暑期学校。

Journal of Medicine and Life Pub Date : 2025-04-01 DOI: 10.25122/jml-2025-1001

Livia Livinț-Popa, Hanna Dragoș, Irina Vlad, Victor Dăbală, Vlad Chelaru, Emanuel Ștefănescu, Bianca Crecan-Suciu, Dafin Mureșanu

引用次数: 0

Optimizing outcomes of partial nephrectomy in patients with tumors in solitary kidneys: a non-systematic review. 孤立肾肿瘤患者部分肾切除术的最佳预后：一项非系统综述。

Journal of Medicine and Life Pub Date : 2025-04-01 DOI: 10.25122/jml-2025-0066

Stelian Ianiotescu, Constantin Gingu, Alexandru Iordache, Adrian Preda, Osama Salloum, Irina Balescu, Nicolae Bacalbasa, Ioanel Sinescu

引用次数: 0

Functional outcomes following nerve transfers for shoulder and elbow reanimation in brachial plexus injuries: a 10-year retrospective study. 神经转移治疗臂丛损伤肩肘复位后的功能结局：一项10年回顾性研究。

Journal of Medicine and Life Pub Date : 2025-04-01 DOI: 10.25122/jml-2025-0079

Cristian-Vladimir Vancea, Florin-Vlad Hodea, Eliza-Maria Bordeanu-Diaconescu, Stefan Cacior, Catalina-Stefania Dumitru, Vladut-Alin Ratoiu, Alexandru Stoian, Ioan Lascar, Dragos Zamfirescu

{"title":"Functional outcomes following nerve transfers for shoulder and elbow reanimation in brachial plexus injuries: a 10-year retrospective study.","authors":"Cristian-Vladimir Vancea, Florin-Vlad Hodea, Eliza-Maria Bordeanu-Diaconescu, Stefan Cacior, Catalina-Stefania Dumitru, Vladut-Alin Ratoiu, Alexandru Stoian, Ioan Lascar, Dragos Zamfirescu","doi":"10.25122/jml-2025-0079","DOIUrl":"10.25122/jml-2025-0079","url":null,"abstract":"Brachial plexus injuries are rare but highly disabling, with major implications for upper limb function and quality of life. Nerve transfers have emerged as a key reconstructive technique, particularly valuable in cases where primary repair or grafting is unfeasible or delayed. This retrospective study analysed functional outcomes following nerve transfers in 37 patients with brachial plexus injury. Motor recovery was assessed using the Medical Research Council scale. Patients were stratified by age, timing of surgery, injury severity, and type of nerve transfer performed. The majority of our cohort consisted of male adults, predominantly injured in motorcycle accidents, while pediatric cases were mostly due to obstetrical trauma. For shoulder reanimation, all patients received spinal accessory to suprascapular nerve transfer, with a subset also undergoing medial triceps branch of the radial nerve to axillary nerve transfer. These techniques resulted in 85.3% of patients achieving shoulder function recovery with M3 or M4 muscle strength, with combined procedures leading exclusively to M3 or M4 muscle strength. For elbow flexion restoration, surgical approaches included intercostal to musculocutaneous nerve transfer, ulnar and median fascicles to musculocutaneous nerve transfer, contralateral C7 to musculocutaneous nerve transfer with ulnar graft, and spinal accessory to musculocutaneous nerve transfer with sural nerve graft. Root grafting procedures using sural nerve grafts or nerve conduits were employed in three pediatric patients. Overall, 84.38% of patients achieved elbow flexion recovery with M3 or M4 muscle strength. These findings reinforce the utility of nerve transfers as a cornerstone in the surgical management of brachial plexus injury.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 4","pages":"375-386"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12094303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cost-effectiveness of Cerebrolysin as an add-on treatment for neurorecovery after traumatic brain injury. 脑溶素作为外伤性脑损伤后神经恢复附加治疗的成本-效果。

Journal of Medicine and Life Pub Date : 2025-04-01 DOI: 10.25122/jml-2025-0087

Stefan Strilciuc, Diana Alecsandra Grad, Cristian Vlădescu, Anca Dana Buzoianu, Carmen Albu, Dafin Fior Mureșanu

{"title":"Cost-effectiveness of Cerebrolysin as an add-on treatment for neurorecovery after traumatic brain injury.","authors":"Stefan Strilciuc, Diana Alecsandra Grad, Cristian Vlădescu, Anca Dana Buzoianu, Carmen Albu, Dafin Fior Mureșanu","doi":"10.25122/jml-2025-0087","DOIUrl":"10.25122/jml-2025-0087","url":null,"abstract":"Traumatic brain injuries (TBIs) are a leading cause of death and long-term disability worldwide, with incidence and injury mechanisms varying by age group and region. Impairment of functional status, diagnoses of anxiety and depression are encountered post-TBI. Studies have shown that Cerebrolysin can have positive effects among TBI survivors. We conducted a cost-effectiveness analysis (CEA) among patients with moderate TBI, using data from the CAPTAIN II trial. This exercise was carried out on a three-month timeline from the provider's perspective. Two models were incorporated in the CEA: control (placebo group) and treatment (Cerebrolysin group). Our analysis showed that Cerebrolysin had a high probability of being cost-effective, based on Glasgow Outcome Scale Extended (GOSE) (in over 80% of patients with moderate TBI), Hospital Anxiety and Depression Scale (HADS) Depression and Anxiety scores (for the former two, in over 95% of patients with moderate TBI), when assuming a lasting effect (12 months) of the CAPTAIN trial intervention protocol. A model-based approach is needed to account for potential sources of bias beyond the 90-day observation period of this clinical trial. Furthermore, economic evaluations incorporating patients diagnosed with all TBI severities are needed.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 4","pages":"387-392"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12094318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Repeat robotic nephron-sparing surgery for metachronous multifocal tumors in a solitary kidney: a case report. 重复机器人肾保留手术治疗单肾异时性多灶性肿瘤1例报告。

Journal of Medicine and Life Pub Date : 2025-04-01 DOI: 10.25122/jml-2025-0059

Stelian Ianiotescu, Constantin Gingu, Irina Balescu, Nicolae Bacalbasa, Ioanel Sinescu

{"title":"Repeat robotic nephron-sparing surgery for metachronous multifocal tumors in a solitary kidney: a case report.","authors":"Stelian Ianiotescu, Constantin Gingu, Irina Balescu, Nicolae Bacalbasa, Ioanel Sinescu","doi":"10.25122/jml-2025-0059","DOIUrl":"10.25122/jml-2025-0059","url":null,"abstract":"We report the case of a 58-year-old male with metachronous renal tumors and a solitary kidney who had previously undergone an open right radical nephrectomy with extended lymphadenectomy for an invasive renal cell carcinoma (RCC) (pT3a N0M0) in November 2013. In May 2022, during routine surveillance, a left lower pole lesion measuring 2.5 × 2 × 1.6 cm was detected, and the patient was submitted to robot-assisted partial nephrectomy (RAPN). The histopathological study confirmed the presence of a pT1a Fuhrman grade 3 clear cell renal carcinoma. In October 2024, follow-up imaging revealed a new upper pole lesion measuring 4 × 3 × 2.3 cm in the left kidney. The patient was submitted to a novel robot-assisted partial nephrectomy, which was successfully completed using selective clamping of the renal artery. The clamping time was 28 minutes (versus 17 minutes during the initial procedure), and the estimated blood loss increased to approximately 300 mL compared to about 100 mL previously, with a console time of 98 minutes. The patient was discharged after the second surgery in good functional status. The final pathology revealed clear cell RCC, Fuhrman grade 2/nucleolar grade 2 (WHO/ISUP 2016), and pT1a, with negative margins. Despite increased technical challenges during reoperation, postoperative renal function remained stable, underscoring the feasibility of repeat RAPN in a solitary kidney.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 4","pages":"393-396"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12094315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Translating theory into practice: students' lived experiences on the utilization of OSVE and role-play for acquiring psychiatric nursing competencies. 将理论转化为实践：学生利用OSVE和角色扮演获得精神科护理能力的生活经验。

Journal of Medicine and Life Pub Date : 2025-04-01 DOI: 10.25122/jml-2024-0383

Amal Ibrahim Khalil, Samirh Said Alqhtani

{"title":"Translating theory into practice: students' lived experiences on the utilization of OSVE and role-play for acquiring psychiatric nursing competencies.","authors":"Amal Ibrahim Khalil, Samirh Said Alqhtani","doi":"10.25122/jml-2024-0383","DOIUrl":"10.25122/jml-2024-0383","url":null,"abstract":"Developing key competencies like communication, empathy, and critical decision-making is crucial in psychiatric nursing education to prepare students for complex clinical environments. This study explored nursing students' experiences in using objective structured video examination (OSVE) and role-play to develop essential psychiatric nursing competencies. A qualitative approach was used, gathering data through focus group discussions and individual interviews with students in a psychiatric nursing course. Various themes emerged, highlighting the advantages and limitations of each teaching method. OSVE offered structured scenarios that improved clinical reasoning and self-assessment, while role-play encouraged real-time interactions and adaptive thinking. Students found that OSVE helped them connect theoretical knowledge to practical applications by allowing them to observe and analyze model behaviors in different psychiatric situations. On the other hand, role-play promoted deeper engagement through realistic patient interactions, boosting confidence and emotional readiness. However, students also faced challenges like performance anxiety during role-play and the need for guidance in OSVE sessions. This study emphasizes the complementary nature of OSVE and role-play in enhancing psychiatric nursing competencies and suggests integrating both methods for comprehensive skill development. The findings offer valuable insights for educators to enhance teaching strategies in psychiatric nursing education, aligning with evidence-based practices to meet student learning needs.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 4","pages":"364-374"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12094309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of dietary and lifestyle interventions in obesity management: a therapeutic protocol at the Diabetes Department, Marius Nasta Institute of Pneumophthisiology, Bucharest, Romania. 饮食和生活方式干预在肥胖管理中的功效：罗马尼亚布加勒斯特Marius Nasta肺病研究所糖尿病科的治疗方案。

Journal of Medicine and Life Pub Date : 2025-03-01 DOI: 10.25122/jml-2024-0417

Oana-Andreea Parlițeanu, Simona Carniciu, Alina Spinean, Cristiana Voineag, Beatrice Mahler

{"title":"Efficacy of dietary and lifestyle interventions in obesity management: a therapeutic protocol at the Diabetes Department, Marius Nasta Institute of Pneumophthisiology, Bucharest, Romania.","authors":"Oana-Andreea Parlițeanu, Simona Carniciu, Alina Spinean, Cristiana Voineag, Beatrice Mahler","doi":"10.25122/jml-2024-0417","DOIUrl":"https://doi.org/10.25122/jml-2024-0417","url":null,"abstract":"The primary objective of this study was to underline the importance of comprehensive medical education in the management of obesity. In clinical practice, patients frequently encounter challenges in achieving weight-related goals. Given that obesity is a major cause of global mortality, we aimed to evaluate the effectiveness of implementing targeted educational interventions on patient outcomes. To this end, we developed a specific dietary plan and educational materials for lifestyle modification administered to 44 patients in the Diabetes Department of Marius Nasta Institute of Pneumophthisiology in Bucharest, Romania. Assessments were conducted at baseline and after a three-month intervention period. The total body weight loss was 11%. BMI reductions were reflected in the redistribution of obesity types. The number of overweight individuals increased from 10 men (22.72%) to 13 men and 5 women, totaling 18 individuals (40.90%, with 29.54% men and 11.36% women). Blood glucose values dropped by 5%, and levels of HbA1c dropped by 0.4% from baseline to follow-up. The SAS severe group went down from 16 patients to 10 patients, and there was an increase in the mild Sleep Apnea Syndrome (SAS) group, increasing from 8 to 14, resulting in a 13.63% overall increase. Our findings indicate that enhanced engagement by the therapeutic team, combined with detailed educational resources and adequate time for their comprehension, improved patient health outcomes, led to weight reduction and a reduction in the severity of comorbidities such as hypertension, dyslipidemia, and sleep apnea, which translated to improved quality of life.","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 3","pages":"208-213"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0