Journal of NeuroEngineering and Rehabilitation最新文献

{"title":"The association of upper limb sensorimotor capacity, everyday inpatient behavior, and the effects of neurorehabilitation in persons with multiple sclerosis and stroke: a mixed-design study.","authors":"Philipp Gulde, Heike Vojta, Stephanie Schmidle, Peter Rieckmann, Joachim Hermsdörfer","doi":"10.1186/s12984-025-01586-z","DOIUrl":"10.1186/s12984-025-01586-z","url":null,"abstract":"<p><strong>Background: </strong>Quantifying and monitoring the sensorimotor state of persons with neurological disease by means of wearables in everyday life has been shown to be a promising approach. To date, the impact of physical activity volumes in fixed epoch approaches has been limiting the feasibility of kinematic analyses of everyday life upper limb use.</p><p><strong>Methods: </strong>Using acceleration and angular velocity signals from wrist-worn sensors, we collected data of healthy controls (n = 12) as well as persons with multiple sclerosis (n = 17) or stroke (n = 14) during everyday life during inpatient neurorehabilitation. An activity recognition algorithm was used to avoid physical activity volume dependencies that come with epoch-based approaches. Behavioral kinematics were compared between samples and associated with clinical test performance. Further, changes of sensorimotor capacity and behavioral kinematics during neurorehabilitation (n = 15) were analyzed.</p><p><strong>Results: </strong>Physical activity volume independence was achieved. Persons with neurological disease showed less activities and longer activity durations. Further, a PCA suggested three underlying components, namely: behavior, neurological state, and physical state. Components scores were lower (worse) for persons with neurological disease, except for behavior. However, component scores of persons with neurological disease showed great variability in all dimensions. Changes in sensorimotor capacity were partially associated with changes in behavioral kinematics, but effects of neurorehabilitation were mostly seen in outcomes associated with the physical state component.</p><p><strong>Conclusions: </strong>Persons with neurological disease showed neurological impairments as well as declines in the physical condition, which can to some extent be seen in behavioral kinematics. Neurorehabilitation appeared to rather affect the physical than the neurological state. By the novel approach using an activity recognizer instead of fixed epochs, it was possible show traces of sensorimotor capacity, as assessed by clinical tests, in kinematics of everyday life behavior.</p>","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"49"},"PeriodicalIF":5.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of an upper limb motion-driven virtual rehabilitation system on residual motor function in patients with complete spinal cord injury： a pilot study.","authors":"Yanqing Xiao, Yang Gao, Hongming Bai, Guiyun Song, Hanming Wang, Jia-Sheng Rao, Aimin Hao, Xiaoguang Li, Jia Zheng","doi":"10.1186/s12984-025-01587-y","DOIUrl":"10.1186/s12984-025-01587-y","url":null,"abstract":"<p><strong>Background: </strong>Assessing residual motor function in motor complete spinal cord injury (SCI) patients using surface electromyography (sEMG) is clinically important. Due to the prolonged loss of motor control and peripheral sensory input, patients may struggle to effectively activate residual motor function during sEMG assessments. The study proposes using virtual reality (VR) technology to enhance embodiment, motor imagery (MI), and memory, aiming to improve the activation of residual motor function and increase the sensitivity of sEMG assessments.</p><p><strong>Methods: </strong>By Recruiting a sample of 12 patients with AIS A/B and capturing surface electromyographic signals before, druing and after VR training, RESULTS: Most patients showed significant electromyographic improvements in activation frequency and or 5-rank frequency during or after VR training. However, one patient with severe lower limb neuropathic pain did not exhibit volitional electromyographic activation, though their pain diminished during the VR training.</p><p><strong>Conclusions: </strong>VR can enhance the activation of patients' residual motor function by improving body awareness and MI, thereby increasing the sensitivity of sEMG assessments.</p>","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"48"},"PeriodicalIF":5.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal arm swing movements in Parkinson's disease: onset, progression and response to L-Dopa.","authors":"M Patera, A Zampogna, L Pietrosanti, F Asci, M Falletti, G Pinola, E Bianchini, G Di Lazzaro, V Rosati, P Grillo, F Giannini, F Fattapposta, G Costantini, A Pisani, G Saggio, Antonio Suppa","doi":"10.1186/s12984-025-01589-w","DOIUrl":"10.1186/s12984-025-01589-w","url":null,"abstract":"<p><strong>Background: </strong>Reduced arm swing movements during gait are an early motor manifestation of Parkinson's disease (PD). The clinical evolution, response to L-Dopa and pathophysiological underpinning of abnormal arm swing movements in PD remain largely unclear. By using a network of wearable sensors, this study objectively assesses arm swing movements during gait in PD patients across different disease stages and therapeutic conditions.</p><p><strong>Methods: </strong>Twenty healthy subjects (HS) and 40 PD patients, including 20 early-stage and 20 mid-advanced subjects, underwent a 6-m Timed Up and Go test while monitored through a network of wearable inertial sensors. Arm swing movements were objectively evaluated in both hemibodies and different upper limb joints (shoulder and elbow), using specific time-domain (range of motion and velocity) and frequency-domain measures (harmonics and total harmonic distortion). To assess the effects of L-Dopa, patients under chronic dopaminergic therapy were randomly examined when OFF and ON therapy. Finally, clinical-behavioral correlations were investigated, primarily focusing on the relationship between arm swing movements and cardinal L-Dopa-responsive motor signs, including bradykinesia and rigidity.</p><p><strong>Results: </strong>Compared to HS, the whole group of PD patients showed reduced range of motion and velocity, alongside increased asymmetry of arm swing movements during gait. Additionally, a distinct increase in total harmonic distortion was found in patients. The kinematic changes were prominent in the early stage of the disease and progressively worsened owing to the involvement of the less affected hemibody. The time- and frequency-domain abnormalities were comparable in the two joints (i.e., shoulder and elbow). In the subgroup of patients under chronic dopaminergic treatment, L-Dopa restored patterns of arm swing movements. Finally, the kinematic alterations in arm swing movements during gait correlated with the clinical severity of bradykinesia and rigidity.</p><p><strong>Conclusions: </strong>Arm swing movements during gait in PD are characterized by narrow, slow, and irregular patterns. As the disease progresses, arm swing movements deteriorate also in the less affected hemibody, without any joint specificity. The positive response to L-Dopa along with the significant correlation between kinematics and bradykinesia/rigidity scores points to the involvement of dopaminergic pathways in the pathophysiology of abnormal arm swing movements in PD.</p>","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"47"},"PeriodicalIF":5.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of brain-computer interface based training on post-stroke upper-limb rehabilitation: a meta-analysis.","authors":"Dan Li, Ruoyu Li, Yunping Song, Wenting Qin, Guangli Sun, Yunxi Liu, Yunjun Bao, Lingyu Liu, Lingjing Jin","doi":"10.1186/s12984-025-01588-x","DOIUrl":"10.1186/s12984-025-01588-x","url":null,"abstract":"<p><strong>Background: </strong>Previous research has used the brain-computer interface (BCI) to promote upper-limb motor rehabilitation. However, the results of these studies were variable, leaving efficacy unclear.</p><p><strong>Objectives: </strong>This review aims to evaluate the effects of BCI-based training on post-stroke upper-limb rehabilitation and identify potential factors that may affect the outcome.</p><p><strong>Design: </strong>A meta-analysis including all available randomized-controlled clinical trials (RCTs) that reported the efficacy of BCI-based training on upper-limb motor rehabilitation after stroke.</p><p><strong>Data sources and methods: </strong>We searched PubMed, Cochrane Library, and Web of Science before September 15, 2024, for relevant studies. The primary efficacy outcome was the Fugl-Meyer Assessment-Upper extremity (FMA-UE). RevMan 5.4.1 with a random effect model was used for data synthesis and analysis. Mean difference (MD) and 95% confidence interval (95%CI) were calculated.</p><p><strong>Results: </strong>Twenty-one RCTs (n = 886 patients) were reviewed in the meta-analysis. Compared with control, BCI-based training exerted significant effects on FMA-UE (MD = 3.69, 95%CI 2.41-4.96, P < 0.00001, moderate-quality evidence), Wolf Motor Function Test (WMFT) (MD = 5.00, 95%CI 2.14-7.86, P = 0.0006, low-quality evidence), and Action Research Arm Test (ARAT) (MD = 2.04, 95%CI 0.25-3.82, P = 0.03, high-quality evidence). Additionally, BCI-based training was effective on FMA-UE for both subacute (MD = 4.24, 95%CI 1.81-6.67, P = 0.0006) and chronic patients (MD = 2.63, 95%CI 1.50-3.76, P < 0.00001). BCI combined with functional electrical stimulation (FES) (MD = 4.37, 95%CI 3.09-5.65, P < 0.00001), robots (MD = 2.87, 95%CI 0.69-5.04, P = 0.010), and visual feedback (MD = 4.46, 95%CI 0.24-8.68, P = 0.04) exhibited significant effects on FMA-UE. BCI combined with FES significantly improved FMA-UE for both subacute (MD = 5.31, 95%CI 2.58-8.03, P = 0.0001) and chronic patients (MD = 3.71, 95%CI 2.44-4.98, P < 0.00001), and BCI combined with robots was effective for chronic patients (MD = 1.60, 95%CI 0.15-3.05, P = 0.03). Better results may be achieved with daily training sessions ranging from 20 to 90 min, conducted 2-5 sessions per week for 3-4 weeks.</p><p><strong>Conclusions: </strong>BCI-based training may be a reliable rehabilitation program to improve upper-limb motor impairment and function.</p><p><strong>Trial registration: </strong>PROSPERO registration ID: CRD42022383390.</p>","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"44"},"PeriodicalIF":5.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: On the role of visual feedback and physiotherapist-patient interaction in robot-assisted gait training: an eye-tracking and HD-EEG study.","authors":"Francesca Patarini, Federica Tamburella, Floriana Pichiorri, Shiva Mohebban, Alessandra Bigioni, Andrea Ranieri, Francesco Di Tommaso, Nevio Luigi Tagliamonte, Giada Serratore, Matteo Lorusso, Angela Ciaramidaro, Febo Cincotti, Giorgio Scivoletto, Donatella Mattia, Jlenia Toppi","doi":"10.1186/s12984-025-01569-0","DOIUrl":"10.1186/s12984-025-01569-0","url":null,"abstract":"","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"46"},"PeriodicalIF":5.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Somatosensory training: a systematic review and meta-analysis with methodological considerations and clinical insights.","authors":"Ryoki Sasaki, Sho Kojima, Kei Saito, Hideaki Onishi","doi":"10.1186/s12984-025-01579-y","DOIUrl":"10.1186/s12984-025-01579-y","url":null,"abstract":"<p><p>Somatosensory training, which involves repetitive somatosensory stimulation, has been employed to enhance somatosensory performance by modulating excitability in the primary somatosensory cortex. This process, known as perceptual learning, can benefit stroke patients with somatosensory deficits. However, its effectiveness in both healthy individuals and stroke patients has not been thoroughly investigated. This systematic review and meta-analysis aimed to evaluate the effectiveness of somatosensory training in these groups. However, no eligible data on stroke patients were identified, excluding them from the analysis. In healthy participants, somatosensory training improved performance in 61.2% datasets, but this effect was observed only at the stimulated site. Additionally, it increased early somatosensory-evoked potential amplitudes in 76.9% of datasets at the stimulated site, with no effect on the non-stimulated site. Despite these moderate improvements, the risk of bias assessment revealed methodological concerns including randomization process, proper control conditions, blinding information, and missing data. The meta-analysis focused on the impact of somatosensory training on tactile two-point discrimination (TPD) in various factors, including different age groups, stimulus durations, stimulus frequencies, and stimulus types. A marked reduction in TPD threshold was observed at the stimulated finger post-training compared to pre-training, though there was a noticeable heterogeneity across studies. In contrast, no significant changes occurred at the non-stimulated fingers, and the subgroup analysis found no specific factors influencing TPD improvements. Although somatosensory training benefits healthy individuals, the variability and methodological concerns highlight the need for further high-quality research to optimize its use in treating somatosensory deficits in stroke patients.</p>","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"43"},"PeriodicalIF":5.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recovr reality - Recover after injury or surgery to the brain and spinal cord with virtual Reality: ideal stage 2a clinical feasibility study.","authors":"William Stephen Bolton, Rohitashwa Sinha, Sara Cooper, Oluwaseyi Adebola, Elisa Stephenson, Seonaid Ewan, Rachel Hunsley, Victoria Kearton, David Stevens, Ryan Koshy Mathew","doi":"10.1186/s12984-024-01499-3","DOIUrl":"10.1186/s12984-024-01499-3","url":null,"abstract":"<p><strong>Aim: </strong>Neurorehabilitation is fundamental to improve outcomes for patients recovering from injury to the central nervous system. Access to neurorehabilitation is limited by resource shortages; the consequences of which are unfulfilled therapy needs, longer hospital stays and detrimental effects on quality of life. Virtual reality (VR) could be used to enhance neurorehabilitation in a self-directed, safe, virtual environment. The aim of this study is to investigate the feasibility of a VR rehabilitation programme in an acute neurosurgical inpatient environment to improve neurorehabilitation.</p><p><strong>Method: </strong>A single-group, prospective, clinical feasibility study was conducted in a tertiary UK neurosurgical department. The study included patients aged 16 and over who had neurosurgical care following surgery or traumatic brain or spinal cord injury. Participants were offered a VR session at least once per day for the first 14 days post-surgery/injury or until discharge, whichever came first, with reasons for non-engagement collected. Primary outcomes were feasibility outcomes and secondary outcomes included rehabilitation engagement.</p><p><strong>Results: </strong>Of the thirty-nine eligible participants approached, thirty-two participants were recruited and received VR at least once. Intervention fidelity was deemed a success, as none of the VR equipment or applications failed. Median time between injury or surgery and first VR use was three days (IQR = 8.25). The Hopkins Rehabilitation Engagement scale and Simulation Sickness Questionnaires were deemed feasible instruments to measure outcomes.</p><p><strong>Conclusions: </strong>We confirmed feasibility of using a VR rehabilitation tool for neurosurgical patients in this study. This now facilitates progression to a multi-centre, prospective, randomised, controlled, unblinded, parallel-group trial of VR-enhanced neurorehabilitation versus standard neurorehabilitation for improving recovery after neurotrauma or neurosurgery.</p>","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"45"},"PeriodicalIF":5.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of robot-assisted gait training within 1 week after stroke onset on degree of gait independence in individuals with hemiparesis: a propensity score-matched analysis in a single-center cohort study.","authors":"Daisuke Kato, Satoshi Hirano, Daisuke Imoto, Takuma Ii, Takuma Ishihara, Daisuke Matsuura, Hirofumi Maeda, Yoshitaka Wada, Yohei Otaka","doi":"10.1186/s12984-025-01581-4","DOIUrl":"10.1186/s12984-025-01581-4","url":null,"abstract":"<p><strong>Background: </strong>Robot-assisted gait training (RAGT) is an effective method for treating gait disorders in individuals with stroke. However, no previous studies have demonstrated the effectiveness of RAGT in individuals with acute stroke. This study aimed to investigate the effects of RAGT initiation within 1 week after onset on degree of gait independence in individuals with hemiparetic stroke.</p><p><strong>Methods: </strong>This retrospective cohort study used propensity-score matching. Individuals admitted to Fujita Health University Hospital after stroke onset and underwent RAGT between March 2017 and June 2023 were enrolled. Ninety-two individuals were eligible and grouped into the acute (≤ 7 days after the onset) and subacute groups (8-90 days after onset). RAGT was conducted using Welwalk, primarily comprising a knee-ankle-foot orthosis type robot worn on one paralyzed lower extremity, with training sessions lasting approximately 40 min/day, occurring 3-7 days/week. The primary outcome was the gait under supervision within 90 days of onset, which was compared between groups using the log-rank test.</p><p><strong>Results: </strong>After propensity-score matching, 36 individuals were included in the analysis, including 18 each in the acute and subacute groups; the participant demographics were not significantly different between the groups. RAGT was initiated at a median of 6 and 25 days after onset in the acute and subacute groups, respectively. The Kaplan-Meier curves after the log-rank test showed a significantly higher percentage and shorter median days to achieve gait under supervision in the acute group than in the subacute group. The cumulative incidence of gait under supervision events at 90 days after onset was 82.2% and 55.6% in the acute and the subacute groups, respectively. Half of the individuals achieved gait under supervision within 49 days and 75 days in the acute and subacute groups, respectively (p = 0.038). No significant differences were observed in the dose of rehabilitation program and gait training per day from onset to achieving gait under supervision.</p><p><strong>Conclusion: </strong>Initiation of RAGT within 1 week after stroke onset in individuals with hemiparesis may reduce the number of days required to achieve gait under supervision and increase the percentage of gait under supervision.</p>","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"42"},"PeriodicalIF":5.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional electrical stimulation for walking in adults with cerebral palsy: a service evaluation.","authors":"Rebecca Walters, Coralie Seary, Ben Beare, Valerie L Stevenson","doi":"10.1186/s12984-024-01538-z","DOIUrl":"10.1186/s12984-024-01538-z","url":null,"abstract":"<p><p>Cerebral palsy (CP) is a neuromotor disorder which can lead to walking difficulties. Functional electrical stimulation (FES) is approved by The National Institute for Health and Care Excellence (NICE) for managing foot drop in upper motor neuron disorders, however there is limited evidence for its use in CP. We discuss a cohort of 26 patients with CP using FES for a 3 month period and longitudinal data for a subset of 11 patients that have used FES for at least 4 years. Patients were referred for the following common barriers to walking: reported falls (54%), foot drop (46%) and tripping (15%). After application of FES at baseline, there was a small clinically insignificant orthotic effect on walking speed (0.01 m/s on/off difference). However, orthotic effects became statistically and clinically significant at three months of continuous use (0.12 m/s on/off difference, p = 0.01) and in the subset of 11 patients this remained significant at four years (0.24 m/s on/off difference, p = 0.01). Patient reported walking satisfaction (numerical rating scale) improved when comparing no-FES versus FES at three months and at four years. FES is a safe, cost-effective treatment option and should be considered, for adults with CP who have walking difficulties.</p>","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"41"},"PeriodicalIF":5.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automatic gait EVENT detection in older adults during perturbed walking.","authors":"Shuaijie Wang, Kazi Shahrukh Omar, Fabio Miranda, Tanvi Bhatt","doi":"10.1186/s12984-025-01560-9","DOIUrl":"10.1186/s12984-025-01560-9","url":null,"abstract":"<p><p>Accurate detection of gait events in older adults, particularly during perturbed walking, is essential for evaluating balance control and fall risk. Traditional force plate-based methods often face limitations in perturbed walking scenarios due to the difficulty in landing cleanly on the force plates. Subsequently, previous studies have not addressed gait event automatic detection methods for perturbed walking. This study introduces an automated gait event detection method using a bidirectional gated recurrent unit (Bi-GRU) model, leveraging ground reaction force, joint angles, and marker data, for both regular and perturbed walking scenarios from 307 healthy older adults. Our marker-based model achieved over 97% accuracy with a mean error of less than 14 ms in detecting touchdown (TD) and liftoff (LO) events for both walking scenarios. The results highlight the efficacy of kinematic approaches, demonstrating their potential in gait event detection for clinical settings. When integrated with wearable sensors or computer vision techniques, these methods enable real-time, precise monitoring of gait patterns, which is helpful for applying personalized programs for fall prevention. This work takes a significant step forward in automated gait analysis for perturbed walking, offering a reliable method for evaluating gait patterns, balance control, and fall risk in clinical settings.</p>","PeriodicalId":16384,"journal":{"name":"Journal of NeuroEngineering and Rehabilitation","volume":"22 1","pages":"40"},"PeriodicalIF":5.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}