Journal of musculoskeletal disorders and treatment最新文献

{"title":"Variations in Chronic Pain Intensity and Physical Function by Age and Sex for Patients with Knee Osteoarthritis","authors":"Odole Adesola, E. Ezinne, Ekechukwu End","doi":"10.23937/2572-3243.1510108","DOIUrl":"https://doi.org/10.23937/2572-3243.1510108","url":null,"abstract":"Objectives: Treatment-seeking behaviour, evaluation and management approach, as well as responsiveness to management by individuals with knee osteoarthritis (OA) could be hampered by variations of common confounding (constant) factors of knee OA; age and sex. Studies that integrate age and sex variations in clinical factors such as pain intensity and physical function are limited. The aim of this study was to determine age and sex variations in pain intensity and physical function among individuals with knee OA in Nigeria. Design/setting/participants/outcome measures: Eightynine consecutively sampled patients diagnosed with knee OA from three selected public (secondary and tertiary) hospitals in Enugu, South-East Nigeria, participated in this cross-sectional survey. Instruments used were Visual Analogue Scale (VAS) and Ibadan Knee or Hip Osteoarthritis Measure (IKHOAM). Data were analysed using Analysis of Variance (ANOVA) and Students’-test with Bonferroni correction. The level of significance was set at 0.05. Results: Significant variations of age in pain intensity between age groups of 20-39 and each of 40-59 years (MD = -3.68, p = 0.01) and 60-79 years (MD = -3.23, p = 0.04) as well as physical function between age groups of 60-79 and each of 20-39 years (MD = 20.85, p = 0.02) and 40-59 years (MD = 10.70, p = 0.03) were observed. There was a significant sex variation in physical function, (F = 9.57, p < 0.05) but not in pain intensity (F = 2.91, p = 0.09) on oneway ANOVA, with females reporting higher scores on pain intensity (5.29 ± 2.97) and lower scores on physical function (64.06 ± 17.26) than males (3.94 ± 2.29 and 78.77 ± 17.08 respectively). Conclusions: Age and sex should be considered by clinicians in management programs for knee OA to address the specific needs of each individual patient.","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85667215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemically Extracted Acellular Nerve Allograft Seeded with SDNF and Autogenic ADSCs for Peripheral Nerve Repairment in a Beagle Model","authors":"Li Wei, C. Lei, Gu Dongqiang, Liang ChunBao, Zhang Shunxin","doi":"10.23937/2572-3243.1510107","DOIUrl":"https://doi.org/10.23937/2572-3243.1510107","url":null,"abstract":"Peripheral nerve repair is a major challenge in clinical practice. Nerve grafting is required to treat severe peripheral nerve defects caused by injuries. Available nerve sources for autologous transplantation are limited. Stem cells offer promise for peripheral nerve repair and regeneration. However, the current lack of Schwann cell phenotype, high costs, and major trauma limit the production of Schwann cells from stem cell differentiation. Thus, the purpose of this study is to investigate the ability of adipose-derived stem cells (ADSCs) to differentiate into the Schwann cell phenotype, after treatment with Schwann cell-derived neurotrophic factor (SDNF) in vitro. ADSCs were isolated and cultured for use in two types of nerve grafts: Acellular allogeneic nerves (ACEN), and acellular allogeneic nerves treated with SDNF (ACEN + SDNF). Chemically extracted, untreated acellular allogeneic nerves (CEN), acellular allogeneic nerves with isolated and cultured autologous SCs (CEN + SCs), and fresh autografts (AG) served as controls. Hematoxylin and eosin (HE) and S100 immunohistochemical staining were performed to observe the cytokine levels in the nerve grafts; enzyme-linked immunosorbent assay (ELISA) and realtime PCR were performed to evaluate the S100 and glial fibrillary acidic protein (GFAP) expression. The acellular nerve allografts seeded with ADSCs and SDNF showed significant S100 and GFAP expressions. No significant statistical differences were observed between the ACEN + SDNF, ACEN + SCs, and AG groups. These data suggest that such acellular nerve allografts should be evaluated as therapeutic strategies for treating severe peripheral nerve defects.","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"231 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76617276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal Biomechanics Concepts of Pediatric Scoliosis and Trunk Shift Applied to Daily Tasks and Sports","authors":"Brunette Jean, Bazergui André","doi":"10.23937/2572-3243.1510106","DOIUrl":"https://doi.org/10.23937/2572-3243.1510106","url":null,"abstract":"The etiology of pediatric idiopathic scoliosis remains poorly understood and it is likely that there is a combination of different factors responsible for its initiation and development. Although the literature highlights the importance of mechanical factors on spinal deformations, the concepts did not receive the attention and consideration they deserve. The Cobb angle is the gold standard value to assess the extent of spinal deformations and risk of progression. However from a biomechanical perspective, it is not the Cobb angle that prevails but rather the distance from the vertebrae to the axis of an ideal straight vertical spine that is well seated and centered on the sacrum. These vertebral offsets along with asymmetrical loads are responsible for additional bending forces that may reach much higher values than the compression forces of a symmetric same load on a straight spine. Forces can be modified, amplified and redistributed by the shape of the spine alone. This article is a review of biomechanics concepts that are applied to the spine with simple concrete examples, and is addressed to clinicians and practitioners in orthopaedics, physical therapy, and sport and exercise science.","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90504730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Risk Factors and Health Care Service Utilization for Low-Back Pain among Nigerian Automobile Technicians","authors":"Ojoawo Adesola Ojo, Mbada Chidozie Emmanuel, Oladele Timilehin, Moda Haruna, Idowu Opeyemi Ayodiipo, S. Ademola, Fatoye Francis","doi":"10.23937/2572-3243.1510092","DOIUrl":"https://doi.org/10.23937/2572-3243.1510092","url":null,"abstract":"Background: Automobile technicians in resource-limited countries depend more on manual than mechanized approach in their work, and as such, may be at high risk for musculoskeletal disorders such as low back pain (LBP). This study was aimed to investigate the prevalence, risk factors and health care service utilization for LBP among Nigerian automobile technicians. Methods: A total of 240 members of the National Association of Automobile Technicians responded in this survey. A previously validated instrument on prevalence, risk factors and health-care-service utilization for LBP was adapted in this study. Data was analysed using descriptive and interferential statistics. Alpha level was set at p < 0.05. Results: Twelve-month and point prevalence of LBP were 79.2% and 75%. On-going LBP was associated with work-related poor posture (46.7%), trauma (13.9%) and lifting of loads (11.7%). LBP mostly led to absenteeism from work (46.8%) and consultation with health practitioners (73.7%). 40% of respondents agreed to have incurred about N1000-N5000 as treatment cost, and 38.7% of the respondents lost about N5000-N10000 as estimated cost in terms of lost hours. Type of automobile activity engaged in (p = 0.483), frequent bending (p = 0.217), lifting objects weighing up to 5 kg (p = 0.071) or up to 25 kg (p = 0.719) and sustained sitting (p = 0.349) or standing (p = 0.996) were not significantly associated with prevalence of LBP. In the bivariate analysis, age (χ2 = 3.298, P = 0.192), marital status (χ2 = 0.098, P = 0.754), type of automobile repairs engaged in (χ2 = 0.493, P = 0.483), lifting objects up to 5 kg (χ2 = 3.269, p = 0.071), lifting objects up to 25 kg (χ2 = 0.130, p = 0.719), sustained sitting (χ2 = 0.840, p = 0.349), and sustained standing (χ2 = 0.002, p = 0.996) were not significantly associated with prevalence of LBP. Level of education (χ2 = 6.121, p = 0.047) was, however, associated with LBP prevalence, although this association was not sustained following logistic regression. Conclusion: There is a high prevalence of LBP among Nigerian automobile technicians, and it results in work absenteeism, economic burden and increased need to seek health care.","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74794324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Feasibility Testing of a Mobile-Phone Application for Exercise in Non-Specific Long-Term Low-Back Pain","authors":"C. Mbada, T. Akintoye, A. Ademoyegun, O. Dada, O. Ayanniyi, A. Odole, IP Gambo, Oe Johnson, FS Olatoye, A. Adejumobi, C. Fatoye, M. Makinde, F. Fatoye","doi":"10.23937/2572-3243.1510091","DOIUrl":"https://doi.org/10.23937/2572-3243.1510091","url":null,"abstract":"Background: There is still lack of rigorous evaluation and evidence for Low-Back Pain (LBP) apps. The objectives of this study were to develop and evaluate the feasibility of a mobile phone-based app of Mechanical Diagnosis and Therapy (MDT) extension exercise; and to examine the correlation between app rating parameters and pain characteristics of patients with non-specific LBP. Methods: A LBP Self-care Mobile-phone App (LBP-SMA) of MDT plus back hygiene was developed following standard iteration and prototyping process. Feasibility of the LBP-SMA was tested in terms of usability, satisfaction and user’s experience using the system usability scale and mobile application rating scale. Quadruple visual analogue scale was used to assess pain intensity of the participants. Data was analyzed using descriptive and inferential statistics at alpha level set at 0.05. Results: Participants’ mean age and pain intensity was 33.8 ± 8.72 years and 45.3 ± 7.23. On a unified scale of 20, functionality (18.5 ± 1.704) and engagement (17.1 ± 2.963) had highest and least objective quality rating on the LBPSMA. Total objective and subjective quality rating of the app was 17.9 ± 1.471 and 18.4 ± 1.173 respectively. LBP-SMA total impact and usability score was 27.2 ± 1.911 indicating high impact and 29.6 ± 1.95 indicating moderate usability. Participants reported that LBP-SMA mostly affects happiness/wellbeing (37.1%), leads to increased behavioural change (48.6%) and targets physical health (100%). There was no significant correlation between participants’ pain characteristics and app rating parameters (p > 0.05). Conclusion: The LBP-SMA has moderate to high usability, functionality, aesthetics and quality rating, and may serve as an effective mobile-app for self-management of longterm LBP.","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"337 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80664447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional Leg Length Discrepancy among Pediatric Scoliosis: A Reversible Neuromuscular Compensation from Craniocervical Junction Misalignment","authors":"Brunette Jean, Gélinas Luc, Chankowsky Jeffrey","doi":"10.23937/2572-3243.1510105","DOIUrl":"https://doi.org/10.23937/2572-3243.1510105","url":null,"abstract":"Background: Leg length discrepancy (LLD) and pelvic obliquity have often been associated with scoliosis in the literature, and neuromuscular contributions have been mentioned as being possibly involved. It is herein hypothesized that a craniocervical junction (CCJ) misalignment (CCJM) may induce a neuromuscular imbalance leading to functional leg length discrepancy, and that re-establishing a proper alignment can result in some LLD disappearance. Methods: A total of n = 40 consecutive scoliotic children aged 7-16 years, 15-50 Cobb angle, were followed for a mean period of 16 months. Children presenting signs and symptoms of CCJM were evaluated with specific radiographs. Patients for whom the misalignment was confirmed received a CCJ adjustment for their re-alignment. Results: All patients presented at first LLD and CCJM. From a mean LLD of 11.0 mm at first presentation (Pre), there was a mean 90% reduction of LLD at the first follow-up visit (1.1 mm) after the re-alignment (mean 15 days Post), and the mean LLD during the complete follow-up period (2.0 mm) was 82% less than that of the mean Pre-LLD, with a mean yearly 1.2 CCJM recurrences and treatments per patient. Conclusion: The results suggest an association between LLD and CCJM among scoliotic children, and LLD may be reversed by means of a CCJ re-alignment which can be sustained. Occasional CCJM recurrences were typically due to falls or hits. The LLD were measured in a horizontal position. It is likely that in a vertical gravitational position, forcing the feet even on the ground, these neuromuscular imbalance forces responsible for this LLD would not disappear but translate into other pelvic and spinal compensatory deviations that may possibly contribute to the development of scoliosis.","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"349 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84867075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and Reliability of the Oxford Shoulder Instability Score Translated into Arabic","authors":"Hanna Sager Samir, Khaja Aliaa Fareed, Bouhamrah Ahmed Khaled, Maqdes Ali","doi":"10.23937/2572-3243.1510082","DOIUrl":"https://doi.org/10.23937/2572-3243.1510082","url":null,"abstract":"Background: The Oxford Shoulder Instability Score, abbre-viated OSIS, is a brief, outcome measure self-reported by the patient suffering shoulder instability. Objectives: Our objective was to translate OSIS into Arabic and validate its psychometric properties via test of the reliability, internal consistency, floor and ceiling effects, and validity. Material & Methods: Fifty-five patients were involved in this survey at the baseline and follow-up (14 days after the baseline). We performed the internal consistency test using Cronbach’s α. We calculated Standard Response Mean (SRM) and Pearson’s Correlation to estimate the construct validity and responsiveness of the Arabic OSIS in comparison to Disability of the Arm and Shoulder and Hand (DASH) Score. Results: The Arabic OSIS had a baseline Cronbach’s α of 0.815 and a follow-up value of 0.860. In addition, Intra-class correlation (ICC) of 0.897; (0.813-0.942) indicated high reliability. Arabic versions of OSIS had a strong correlation with DASH score (r = 0.77, p = 0.003) which suggested a good construct validity. Also, moderately correlated changes of baseline to follow-up in OSIS indicated moderate responsiveness. We did not observe any relevant floor and ceiling effect among the responses. Conclusion: Overall, the Arabic version of OSIS proved to be a good and reliable diagnostic tool for patients with shoulder instability.","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86061202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disc Desiccation in Low Impact Young Trauma Victims","authors":"F. Steven, Michael Burgio","doi":"10.23937/2572-3243.1510085","DOIUrl":"https://doi.org/10.23937/2572-3243.1510085","url":null,"abstract":"Objective: To consider evidence that indicates disc desiccation occurs with regularity in young individuals, despite reports to the contrary. Clinical Features: The clinical histories of 168 chiropractic patients under the age of 50 were reviewed in such a manner that individual patients cannot be identified. Outcome: 20 individuals under the age of 50 were found to exhibit disc desiccation, an occurrence of approximately 12%. It was also indicated that disc desiccation appears to occur with slightly greater frequency in women. Conclusion: Disc desiccation is more prevalent in young trauma victims than was previously believed. Concern regarding sample size was discussed, as were suggestions for further research, such as larger sample size, consideration of the direction of impact, the effects of health or obesity upon the occurrence and/or degree of injury.","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"201 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82814867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metatropic Dysplasia - Description of a Newborn with Suspected Epiphyseal Dysplasia","authors":"Byrwa Agnieszka, M. Izabela, A. Paulina, J. Elzbieta","doi":"10.14740/jem598","DOIUrl":"https://doi.org/10.14740/jem598","url":null,"abstract":"","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79724996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Muscle Magnetic Resonance Imaging versus Clinical Function in Duchenne Muscular Dystrophy","authors":"Liang Yingyin, Li Jie, Yang Chen, Xu Xue, Li Guidian, He Rongxing, Zhang Cheng","doi":"10.23937/2572-3243.1510069","DOIUrl":"https://doi.org/10.23937/2572-3243.1510069","url":null,"abstract":"Background: Impairment in patients with Duchenne muscular dystrophy (DMD) has been evaluated primarily by muscle fiber microscopy examination. Pathologic examination is limited by the choice of muscle and the invasiveness of muscle biopsy. Magnetic resonance imaging (MRI) of the muscle is a noninvasive method of evaluating muscle preservation. Objective: To compare muscle MRI and clinical function in patients at different stages (from early to terminal stage) of DMD, and to evaluate the correlation between fatty infiltration grade on MRI and clinical functional scale. Materials and methods: Thirty-one boys with DMD, of mean age 7.76 ± 4.99 years, underwent evaluation of clinical functional score grades (scores 1-4) while undergoing muscle MRI of the lower leg, thigh and pelvis. Fatty infiltration grade of 31 muscles was assessed by T1WI MRI using the Mercuri scale (from 0 to 4). Spearman correlation analysis was performed to assess the correlation between T1WI fatty infiltration grade and clinical functional grade. Results: Seventeen muscles showed positive correlations between fatty infiltration grade on T1WI MRI and clinical function. The gluteus maximus, adductor magnus, and gastrocnemius muscles were the most representative, because they were involved during early stages of DMD and their shapes were easier to distinguish on MRI. The obturator internus, gracilis and sartorius muscles were rarely involved until the terminal stage of disease. Damage to these three muscles could be used to predict terminal stage. Fatty infiltration grade on muscle MRI corresponded to microscopic parameters, including a reduced number of muscle cells, arrangement disorder, and fatty and connective tissue infiltration. Conclusion: The results of muscle MRI showed good correlation with clinical function in patients with DMD. Because muscle MRI is a reliable and non-invasive method of assessing muscle damage, MRI is useful in the diagnosis and follow-up of patients with DMD. The Mercuri scale, which measures fatty infiltration on T1WI MRI, is a convenient method of evaluating disease severity and progression.","PeriodicalId":16374,"journal":{"name":"Journal of musculoskeletal disorders and treatment","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90283835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}