Journal of Life Science最新文献_第4页

Egg Quality Characteristics of Layer Chickens Reared with Tenebrio molitor Larvae 黄粉虫幼虫饲养蛋鸡的蛋品质特性

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.10.860

Dohyeon Kim, Dong-Hyun Kim, Hyun-Woo Park, Jin Kwon Kim, Sam-Woong Kim, T. W. Kim, Byeong-Jin Lee, Daniel Son, Il-Suk Kim

引用次数: 0

Anti-inflammatory and Anti-bacterial Activities of Artemisia iwayomogi Kitamura Extract Fractions 北村艾蒿提取物的抗炎抑菌活性研究

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.1.40

S. Sin, Won Min Jeong, Y. Kil, Dong Yeol Lee, Sang Gon Kim, Young-Min Goo

{"title":"Anti-inflammatory and Anti-bacterial Activities of Artemisia iwayomogi Kitamura Extract Fractions","authors":"S. Sin, Won Min Jeong, Y. Kil, Dong Yeol Lee, Sang Gon Kim, Young-Min Goo","doi":"10.5352/JLS.2020.30.1.40","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.1.40","url":null,"abstract":"This study investigated the anti-bacterial and anti-inflammatory activities of Artemisia iwayomogi Kitamura for medical and food additive applications. A 70% methanol extract of A. iwayomogi Kitam. was fractionated with a series of solvents in order of increasing polarity; these fractionated extracts showed high 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) scavenging activity in the ethyl acetate fractions and high 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity in both the ethyl acetate and chloroform fractions. Levels of total phenolics and flavonoids were highest in the ethyl acetate fraction extracts. Eight bacteria were then treated with the A. iwayomogi Kitam. extract fractions and most showed similar or lower levels of anti-bacterial activity when compared to the control group, except for Staphylococcus aureus. In addition, the anti-oxidant activities of the ethyl acetate fractions of the A. iwayomogi Kitam. extract were higher than those of the other fractions. To confirm the anti-inflammatory activity of the extract fractions, we applied them to RAW 264.7 cells using LPS, and the results indicate that an ethyl acetate fraction at 250 μg/ml concentration inhibits nitric oxide production. This study demonstrates that an ethyl acetate fraction of A. iwayomogi Kitam. extract inhibits bacterial and inflammatory activities and could be useful as a potential source of bioactive compounds.","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"87 1","pages":"40-44"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74955610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Antioxidant effect and iNOS, COX-2 Expression Inhibition on RAW 264.7 Cell of Mangifera indica L. Leafs 芒果叶片RAW 264.7细胞的抗氧化作用及iNOS、COX-2表达抑制

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.9.783

Dan-Hee Yoo, Leeinchul

引用次数: 1

Genetic Effects of Molecular Markers Related to Carcass Traits in Hanwoo Cattle 韩宇牛胴体性状相关分子标记的遗传效应

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.3.230

S. Shin, E. Chung

引用次数: 0

Effect of Allium cepa (red) and Angelica gigas Nakai on Hair-growth Promotion in C57BL/6 Mice 红葱和当归对C57BL/6小鼠毛发生长的促进作用

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.11.990

Jin-Young Lee, J. Dong, J. Kang

引用次数: 0

Physiological Activity of Methanol Extracts from Sambucus sieboldiana var. miquelii (Nakai) Hara 三叶草甲醇提取物的生理活性研究

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.11.965

Yu Jin Oh, Hae Jin Cho, Hyun Sim Woo, Jun-Gi Byeon, Yeong-Su Kim, D. Kim

引用次数: 1

Recent Perspectives on Oncoplastic Breast Surgery in Korea 韩国乳腺肿瘤整形手术的最新进展

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.6.563

Taewoo Kang

引用次数: 1

Anti-neuroinflammatory Effect of Teleogryllus emma Derived Teleogryllusine in LPS-stimulated BV-2 Microglia 远端灰鼠衍生的远端灰鼠亮氨酸在lps刺激的BV-2小胶质细胞中的抗神经炎作用

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.11.999

M. Seo, Yong pyo Shin, H. Lee, Minhee Baek, Joon-Ha Lee, In-woo Kim, Jae‐Sam Hwang, Mi-Ae Kim

{"title":"Anti-neuroinflammatory Effect of Teleogryllus emma Derived Teleogryllusine in LPS-stimulated BV-2 Microglia","authors":"M. Seo, Yong pyo Shin, H. Lee, Minhee Baek, Joon-Ha Lee, In-woo Kim, Jae‐Sam Hwang, Mi-Ae Kim","doi":"10.5352/JLS.2020.30.11.999","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.11.999","url":null,"abstract":"The suppression of neuroinflammatory responses in microglial cells, well known as the main immune cells in the central nervous system (CNS), are considered a key target for improving the progression of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. Teleogryllus emma is widely consumed around the world for its broad-spectrum therapeutic effect. In a previous work, we performed transcriptome analysis on T. emma in order to obtain the diversity and activity of its antimicrobial peptides (AMPs). AMPs are found in a variety of species, from microorganisms to mammals. They have received much attention as candidates oftherapeutic drugs for the treatment of inflammation-associated diseases. In this study, we investigated the anti-neuroinflammatory effect of Teleogryllusine (VKWKRLNNNKVLQKIYFVKI-NH2) derived from T. emma on lipopolysaccharide (LPS) induced BV-2 microglia cells. Teleogryllusine significantly inhibited nitric oxide (NO) production without cytotoxicity, and reducing pro-inflammatory enzymes expression such as inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). In addition, Telegryllusine also inhibited the expression of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) through down-regulation of the mitogen-activated protein kinases (MAPKs) and nuclear factor kappa B (NF-κB) signaling pathway. These results suggest that T. emma-derived Teleogryllusine could be a good source of functional substances that prevent neuroinflammation and neurodegenerative diseases.","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"11 1","pages":"999-1006"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79972495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Evaluation of the Anti-oxidant Activity of Fermented Defatted Sesame Seeds 发酵脱脂芝麻抗氧化活性的评价

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.5.452

Eunji Kim, Seung-Wha Jo, Eun-Jung Yim, Kum-Suk Kim, B. Choi, Nam-rye Lee, Do-Youn Jung

引用次数: 0

Physiological Roles of Phospholipase Cγ and Its Mutations in Human Disease 磷脂酶Cγ及其突变在人类疾病中的生理作用

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.9.826

H. Jang, J. Choi, Jongsoo Chang

引用次数: 0