Journal of Life Science最新文献_第3页

Distribution of Subgroups in Pseudomonas syringae pv. actinidiae Biovar 3 Strains Isolated from Korea 丁香假单胞菌的亚群分布。actinidiae Biovar 3韩国分离株

Journal of Life Science Pub Date : 2021-01-01 DOI: 10.5352/JLS.2021.31.1.52

Young Sun Lee, Gyoung-Hee Kim, J. Jung

引用次数: 1

Anti-inflammatory Activities of Apple Extracts and Phloretin 苹果提取物和根皮素的抗炎作用

Journal of Life Science Pub Date : 2021-01-01 DOI: 10.5352/JLS.2021.31.2.158

Geun-Ho Kim, Eunjoo Lee, S. Ryu, H. Sohn, Jongsik Kim

引用次数: 0

Comparison of the Cytoprotective Effects of Several Natural and Synthetic Compounds against Oxidative Stress in Human Retinal Pigment Epithelial Cells 几种天然和合成化合物对人视网膜色素上皮细胞氧化应激保护作用的比较

Journal of Life Science Pub Date : 2021-01-01 DOI: 10.5352/JLS.2021.31.2.126

D. H. Kim, Jeong Hwan Kim, Seh-Kwang Park, J. Jeong, Mi-young Kim, S. Nam, Hyesook Lee, Yung-Hyun Choi

引用次数: 0

Evaluation of Lipid Accumulation’s Inhibitory Activity on 3T3-L1 Cells with Red Yeast Barley Extracts 红曲大麦提取物对3T3-L1细胞脂质积累抑制作用的研究

Journal of Life Science Pub Date : 2021-01-01 DOI: 10.5352/JLS.2021.31.2.192

G. Kwon, Byunghyuk Kim, Jun-Hyeong Lee, H. Hwang, Jung-Bok Lee

{"title":"Evaluation of Lipid Accumulation’s Inhibitory Activity on 3T3-L1 Cells with Red Yeast Barley Extracts","authors":"G. Kwon, Byunghyuk Kim, Jun-Hyeong Lee, H. Hwang, Jung-Bok Lee","doi":"10.5352/JLS.2021.31.2.192","DOIUrl":"https://doi.org/10.5352/JLS.2021.31.2.192","url":null,"abstract":"Red yeast rice has been extensively used as food and traditional medicine for thousands of years in East Asian countries. It is produced by the fermentation of a particular yeast (in general, Monascus purpureus) as rice and various cereals (barley, soybean, etc.). Monascus sp. produces many secondary metabolites during its growth, including pigments, monacolins, and γ-aminobutyric acid. Some metabolites—specifically, monacolin K, γ-aminobutyric acid, dimerumic acid, and monascus pigments—have been reported to lower cholesterol and blood pressure while showing anti-obesity effects. In this study, we investigated the anti-obesity effect of ethanol extract from red yeast barley (RYB) fermented with Monascus sp. BHN-MK 2 on 3T3-L1 cells. The anti-obesity effects of RYB extract were examined: its lipid accumulation inhibitory effect was tested by Oil Red O staining, and obesity-related mRNA expression levels were tested by real-time RT-PCR in MDI stimulated 3T3-L1 cells. The intracellular lipid content of MDI-stimulated 3T3-L1 cells decreased significantly to 5.04%, 12.24%, and 23.52% in response to 200, 400, and 800 μg/ml RYB, respectively. Moreovers, we evaluated that RYB extract significantly downregulated the expression of C/EBPα, SREBP-1, and PPAR-γ gene in a dose-dependent manner. As a result, red yeast barley ethanol extracts exerted the strongest anti-obesity effects. Also, the results indicate that red yeast barley could be used as a functional anti-obesity food material.","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"14 1","pages":"192-198"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91212920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Significance of Cancer Stem Cells in Canine Mammary Gland Tumors 肿瘤干细胞在犬乳腺肿瘤中的意义

Journal of Life Science Pub Date : 2021-01-01 DOI: 10.5352/JLS.2021.31.2.248

Seo-Young Park, Yeong-Bin Baek, Sang-Ik Park, Chang-Min Lee, Sung-Hak Kim

引用次数: 0

Immunomodulatory Effects of Euglena gracilis Extracts 细叶桉提取物的免疫调节作用

Journal of Life Science Pub Date : 2021-01-01 DOI: 10.5352/JLS.2021.31.2.183

Sun Yu, B. Park, Ji Won Kim, You Lim Hwang, S. H. Kim, Sunah Kim, Lee Tae-Ho, AhnSoon Cheol

引用次数: 0

Phylogenetic Diversity and Antibacterial Activity of Bacteria from Shindari of Jeju Traditional Fermented Food 济州传统发酵食品Shindari细菌的系统发育多样性及抑菌活性

Journal of Life Science Pub Date : 2021-01-01 DOI: 10.5352/JLS.2021.31.1.73

Young-Soo Ryu, M. Heo

引用次数: 0

Inhibitory Effect of Lactic Acid Bacteria-fermented Chrysanthemum indicum L. on Adipocyte Differentiation through Hedgehog Signaling 乳酸菌发酵菊通过Hedgehog信号抑制脂肪细胞分化的作用

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.6.532

J. Choi, J. Lim, Bo Ram Sim, Yung-Hun Yang

引用次数: 1

Improvement of Artificial Antibody Secretion Using Supercharged Protein 利用增压蛋白改进人工抗体分泌

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.5.420

Ji-Young Park, H. Choi, Hyejin Lee, J. Ahn

引用次数: 0

Correlation between Peripheral Neuropathy and Cognitive Factors in Type 2 Diabetic Patients 2型糖尿病患者周围神经病变与认知因素的相关性

Journal of Life Science Pub Date : 2020-01-01 DOI: 10.5352/JLS.2020.30.3.250

Won-Kyung Yang, Jong Kuk Kim, K. Park, S. Suh, Hye-Jeong Lee, M. Park

{"title":"Correlation between Peripheral Neuropathy and Cognitive Factors in Type 2 Diabetic Patients","authors":"Won-Kyung Yang, Jong Kuk Kim, K. Park, S. Suh, Hye-Jeong Lee, M. Park","doi":"10.5352/JLS.2020.30.3.250","DOIUrl":"https://doi.org/10.5352/JLS.2020.30.3.250","url":null,"abstract":"Diabetes is a well-known risk factor for dementia and cognitive impairment. Diabetic polyneuropathy (DPN) is the most prevalent microvascular complication in type 2 diabetes mellitus (T2DM) patients. The purpose of this study was to evaluate the relation between diabetic peripheral polyneuropathy and cognitive factors in T2DM patients. Retrospective chart review of type 2 diabetic patients with results of a nerve conduction study (NCS) and a neurocognitive study. A total of 19 patients were included. DPN was defined using data from a nerve conduction study: a score of less than 24 in the Korean version of the Mini-Mental State Examination (K-MMSE) was considered as an indicator of cognitive impairment (CI). The mean age of the 19 patients was 71.6±5.0 years. The mean duration of diabetes was 8.4±9.1 years, and the mean HbA1c level was 8.1±1.8%. DPN was present in 7 of the 19 patients. Based on the K-MMSE score, CI was diagnosed in eight patients. The mean K-MMSE scores and the prevalence of CI was not different between the groups with and without DPN. There was no significant difference in DPN prevalence between the groups with and without CI. Education was significantly correlated with cognitive factors. Only the digit span-forward among the cognitive factors showed a significant negative correlation with nerve conduction velocity. In conclusion, the longer education period was associated with higher cognitive function and no significant correlation was observed between diabetic peripheral neuropathy and cognitive dysfunction in type 2 diabetic patients. Further prospective research is needed in the future.","PeriodicalId":16322,"journal":{"name":"Journal of Life Science","volume":"38 1","pages":"250-259"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90781640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0