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2013 6th International Conference on Biomedical Engineering and Informatics最新文献

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Improving the sound quality of an electronic voice box 改进电子音箱的音质
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2014-12-01 DOI: 10.1109/APSIPA.2014.7041703
N. Yan, M. Ng, Tan Lee
{"title":"Improving the sound quality of an electronic voice box","authors":"N. Yan, M. Ng, Tan Lee","doi":"10.1109/APSIPA.2014.7041703","DOIUrl":"https://doi.org/10.1109/APSIPA.2014.7041703","url":null,"abstract":"The present project attempted to design the next generation electronic voice box by modifying the driving signal of the device. Two steps were involved in the project. The first step involved designing a working minishaker system using existing commercial miniature shaker system that functions similarly to an electrolarynx, but with variable driving signals (type and frequency). The second step involved carrying out perceptual experiments to examine listeners' intelligibility and acceptability of the voice produced with the minishaker system associated with different driving signals by both normal laryngeal speakers and laryngectomized speakers of Cantonese. Upon completion of the experiments, the five driving signals and the five driving frequencies that are associated with the highest acceptability scores were obtained. It is anticipated that the next generation electronic voice box should be designed based on these driving signals and frequencies should yield better and more natural sound quality.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125415450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cytotoxicity of silver nanoparticles was influenced by dispersion media in HepG2 cells 银纳米颗粒对HepG2细胞毒性的影响
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2013-12-01 DOI: 10.1109/BMEI.2013.6746963
Yuying Xue, Yanmei Huang, F. Gong, Ting Zhang, M. Tang
{"title":"Cytotoxicity of silver nanoparticles was influenced by dispersion media in HepG2 cells","authors":"Yuying Xue, Yanmei Huang, F. Gong, Ting Zhang, M. Tang","doi":"10.1109/BMEI.2013.6746963","DOIUrl":"https://doi.org/10.1109/BMEI.2013.6746963","url":null,"abstract":"The present investigations were carried out to evaluate the cellular toxic effects of silver nanoparticles (AgNPs) suspended in different solvents using human hepatocellular carcinoma cell line (HepG2). MTT assay was used to examine the proliferation activities of cells. The effects of AgNPs on cell cycle and apoptosis were analyzed using flow cytometry. The ionization of AgNPs in different dispersion media (deionized water, PBS, saline and cell culture medium) was found to be different, with the concentrations of silver ion in deionized water were the highest in all suspensions. AgNPs could inhibit the viability of HepG2 cells. AgNPs (40, 80, 160 μg/mL) could cause cell cycle arrest in G2/M phase and significantly increase the apoptosis rate in HepG2 cells after exposure for 24 or 48 h, especially suspended in deionized water. The results showed that AgNPs possessed cytotoxic effects to HepG2 cells with a time/dose-dependent manner. The cytotoxicity was also affected by the dispersion media of AgNPs.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115384177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Field free line generation for Magnetic Particle Imaging based on the Mirror Rule 基于镜像规则的磁粒子成像无场线生成
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2013-12-01 DOI: 10.1109/BMEI.2013.6746904
X. Lv, Zheng Wang, Wenhui Yang
{"title":"Field free line generation for Magnetic Particle Imaging based on the Mirror Rule","authors":"X. Lv, Zheng Wang, Wenhui Yang","doi":"10.1109/BMEI.2013.6746904","DOIUrl":"https://doi.org/10.1109/BMEI.2013.6746904","url":null,"abstract":"A novel approach for the generation of the Field Free Line (FFL) with four circular coils is proposed in this paper. A rule for the generation of FFL with four circular coils called Mirror Rule is established and proved based on Biot-Savart Law. Calculations of the FFL field distribution were performed. The relationships between the coil rotation angle and the field inhomogeneity as well as field efficiency were studied. The Mirror Rule for FFL generation and the calculation results were also testified by FEM simulation using the Maxwell software. Based on the Mirror Rule, MPI using a dual-surface FFL generator is able to avoid the patient rotation and promising for future clinical usage.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"272 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124404736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A parameterized enumeration algorithm for the haplotype assembly problem 单倍型装配问题的参数化枚举算法
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2013-12-01 DOI: 10.1109/BMEI.2013.6746986
Yang Yang, Minzhu Xie
{"title":"A parameterized enumeration algorithm for the haplotype assembly problem","authors":"Yang Yang, Minzhu Xie","doi":"10.1109/BMEI.2013.6746986","DOIUrl":"https://doi.org/10.1109/BMEI.2013.6746986","url":null,"abstract":"Given DNA sequence fragments from a pair of chromosomes, the goal of the haplotype assembly problem is to reconstruct the two haplotypes of the underlying chromosomes. Many heuristic algorithms and exact algorithms have been introduced for the problem, and they aim to reconstruct a pair of haplotypes that is optimal or near-optimal. However given an input fragments data the optimal solution may be not unique, but these algorithms can only choose one randomly or the one they find at first. This paper proposes a parameterized enumeration algorithm for the Minimum Single Nucleotide Polymorphism (SNP) Removal model of the problem. Extensive experiments show that the algorithm can effectively provide multiple optimal solutions to biologists for further analyses.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124245735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A PET study of discrimination of cerebral glucose metabolism in Alzheimer's disease and mild cognitive impairment 阿尔茨海默病与轻度认知障碍患者脑糖代谢鉴别的PET研究
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2013-12-01 DOI: 10.1109/BMEI.2013.6746897
Haining Sun, Bin Hu, Zhijun Yao, M. Jackson
{"title":"A PET study of discrimination of cerebral glucose metabolism in Alzheimer's disease and mild cognitive impairment","authors":"Haining Sun, Bin Hu, Zhijun Yao, M. Jackson","doi":"10.1109/BMEI.2013.6746897","DOIUrl":"https://doi.org/10.1109/BMEI.2013.6746897","url":null,"abstract":"Imaging cerebral glucose metabolism with positron emission tomography (PET) has been widely used in studying Alzheimer's disease (AD) and mild cognitive impairment (MCI). In this study, we used fluoro-deoxyglucose (FDG) PET images to investigate reduced glucose metabolism in 90 AD subjects, 90 MCI subjects and 90 healthy elderly normal controls (NC). Compared to NC, the AD showed a significant hypometabolism in left and right middle temporal, left cingulate gyrus, medial frontal gyrus and left parahippocampal gyrus. Compared to NC, the MCI showed a significant hypometabolism in the right inferior temporal gyrus and right fusiform gyrus. Compared to MCIs, the AD also showed a significant hypometabolism in left and right middle temporal, left cingulate gyrus, left angular gyrus and right parahippocampal gyrus. This study demonstrates the different cerebral metabolic patterns of AD, MCI and controls. It also shows that glucose metabolism is a sensitive measure of change in cognition and functional ability in AD and MCI, and that might be valuable in predicting future cognitive decline.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"455 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125789354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Localization of epileptic foci based on scalp EEG and approximate entropy 基于头皮脑电图和近似熵的癫痫病灶定位
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2013-12-01 DOI: 10.1109/BMEI.2013.6746941
Zhen Zhang, Yi Zhou, Tian Mei, Ziyi Chen, Shouhong Du, Xianghua Tian
{"title":"Localization of epileptic foci based on scalp EEG and approximate entropy","authors":"Zhen Zhang, Yi Zhou, Tian Mei, Ziyi Chen, Shouhong Du, Xianghua Tian","doi":"10.1109/BMEI.2013.6746941","DOIUrl":"https://doi.org/10.1109/BMEI.2013.6746941","url":null,"abstract":"In order to reduce damage from invasive check and save resources during iEEG (intracranial electroencephalogram) collection, especially when large area of craniotomy is operated, we combined nonlinear dynamics with medical statistical methods to carry out epileptic foci localization by analyzing scalp EEG (electroencephalogram) which can be collected by noninvasive way. Firstly, ApEn (approximate entropy) was measured to get the complexity of EEG quantitatively. Secondly, a physiological reference range of ApEn which was caculated from normal EEG was set up and different degrees of the complexity changes on each electrode during seizures were obtained. Based on the above steps, the preliminary localization of epileptic foci could be finally achieved. We analyzed scalp EEG data for a total of six patients who had been diagnosed as partial epilepsy, and won the success of the preliminary locations on these six patients.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130050570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Design and implementation of elliptic/dual-level microwave amplifiers using Z domain techniques for biomedical applications 椭圆/双能级微波放大器的Z域设计与实现
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2013-12-01 DOI: 10.1109/BMEI.2013.6746948
Tai-Chuan Wang, C. Hsue, Sen-Te Chang, Tsun-Mu Chen
{"title":"Design and implementation of elliptic/dual-level microwave amplifiers using Z domain techniques for biomedical applications","authors":"Tai-Chuan Wang, C. Hsue, Sen-Te Chang, Tsun-Mu Chen","doi":"10.1109/BMEI.2013.6746948","DOIUrl":"https://doi.org/10.1109/BMEI.2013.6746948","url":null,"abstract":"Two amplifiers designed with z domain technique are presented in this paper. The first amplifier is featured with frequency response of elliptic equation, which has the defined operating band from 1.8GHz to 2.7GHz. The second amplifier is a dual-level amplifier which is designed with the aid of Yule-Walker scheme. This amplifier shows a 3-dB difference in amplitude response in the operating band. The design of both amplifiers demonstrates the advantages of z-domain technique and Yule-Walker scheme, which leads us to define complex frequency response of an amplifier arbitrarily. The amplifier characteristics including S parameter, 1-dB gain compression point (P1dB), and noise figure are measured and discussed in the paper.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"236 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134055799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An approach for modeling and analyzing the communication protocols in a telemedicine system 远程医疗系统中通信协议的建模与分析方法
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2013-12-01 DOI: 10.1109/BMEI.2013.6747029
Junhua Ding, Dongmei Zhang
{"title":"An approach for modeling and analyzing the communication protocols in a telemedicine system","authors":"Junhua Ding, Dongmei Zhang","doi":"10.1109/BMEI.2013.6747029","DOIUrl":"https://doi.org/10.1109/BMEI.2013.6747029","url":null,"abstract":"Telemedicine systems are a type of safety critical systems that require high quality in system design and implementation. The quality of the communication protocols between a user and a service provider in a telemedicine system is especially important to the success of a telemedicine system. Therefore, a rigorous modeling and analysis approach to ensure the quality of the communication protocols in a telemedicine system is necessary. However, most of the rigorous modeling and analysis approaches were developed based on formal methods, which are not practical for large systems. In addition, many of existing approaches are only useful in a particular development phase such as design or implementation but not the whole life cycle of system development. In this paper, we introduce an integrated modeling and analysis approach that enhances the quality of software testing though injecting the rigorousness of formal methods into it to ensure the correctness of a system at each development phase. The idea of the approach and its effectiveness are illustrated by case study of the communication protocols in a telemedicine system. The communication protocol is first modeled using a high-level Petri nets, and then the model is analyzed with model checking, simulation, reachability analysis, and testing. According to a selected test adequacy criterion, the adequate tests are automatically generated for the model, and then they are converted into the tests to test the system implementation.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"13 14","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131505179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A quaternion antisymmetric and persymmetric matrix inverse problem from Hopfield neural networks Hopfield神经网络的四元数反对称和过对称矩阵反问题
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2013-12-01 DOI: 10.1109/BMEI.2013.6747015
Haixia Chang
{"title":"A quaternion antisymmetric and persymmetric matrix inverse problem from Hopfield neural networks","authors":"Haixia Chang","doi":"10.1109/BMEI.2013.6747015","DOIUrl":"https://doi.org/10.1109/BMEI.2013.6747015","url":null,"abstract":"This paper considers the antisymmetric and per-symmetric solution to a matrix inverse problem AX = B for A and the optimal approximation over the quaternion field H. We first give the specified structure of the antisymmetric and persymmetric quaternion matrix. Then we derive the necessary and sufficient conditions for the existence of and the general expression for the antisymmetric and persymmetric solution of the matrix equation mentioned above. Moreover, we obtain the expression of the solution to optimal approximation problem and corresponding numerical algorithm is also presented. The work is motivated and illustrated with a problem of Hopfield neural networks.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"28 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131545637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automatic measurement of cup to disc ratio for diagnosis of glaucoma on retinal fundus images 自动测量杯盘比诊断青光眼视网膜眼底图像
2013 6th International Conference on Biomedical Engineering and Informatics Pub Date : 2013-12-01 DOI: 10.1109/BMEI.2013.6746900
Azin Poshtyar, J. Shanbehzadeh, H. Ahmadieh
{"title":"Automatic measurement of cup to disc ratio for diagnosis of glaucoma on retinal fundus images","authors":"Azin Poshtyar, J. Shanbehzadeh, H. Ahmadieh","doi":"10.1109/BMEI.2013.6746900","DOIUrl":"https://doi.org/10.1109/BMEI.2013.6746900","url":null,"abstract":"Glaucoma is the second leading cause of blindness in the world. It is estimated that 66.8 million people in the world have glaucoma, with 6.7 million bilaterally blind from this disease. One of the glaucoma symptoms is that the cup enlarges until it occupies most of the disc area. This results in blindness. The cup-to-disc ratio is a measurement used in ophthalmology to detect glaucoma and assess its progression. This paper presents an approach to automatic calculation of cup to disc ratio using accurate detection of disc and cup, and quantitative determination of their areas in retinal fundus images to diagnose glaucoma. This method is computationally efficient. Experimental results indicate sufficient validity of the quantitative analysis to diagnose glaucoma.","PeriodicalId":163211,"journal":{"name":"2013 6th International Conference on Biomedical Engineering and Informatics","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115210547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
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