Journal of Interventional Cardiac Electrophysiology最新文献

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Clinical phenotypes and outcomes associated with improved left ventricular ejection fraction after biventricular pacing. 双室起搏后左室射血分数改善的临床表型和结果。
IF 2.7 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-04-09 DOI: 10.1007/s10840-025-02040-9
Sameer A Kunte, Lurdes Y T Inoue, William T Abraham, John G F Cleland, Anne B Curtis, Daniel J Friedman, Michael R Gold, Valentina Kutyifa, Cecilia Linde, Anthony S Tang, Gillian D Sanders, Sana M Al-Khatib
{"title":"Clinical phenotypes and outcomes associated with improved left ventricular ejection fraction after biventricular pacing.","authors":"Sameer A Kunte, Lurdes Y T Inoue, William T Abraham, John G F Cleland, Anne B Curtis, Daniel J Friedman, Michael R Gold, Valentina Kutyifa, Cecilia Linde, Anthony S Tang, Gillian D Sanders, Sana M Al-Khatib","doi":"10.1007/s10840-025-02040-9","DOIUrl":"10.1007/s10840-025-02040-9","url":null,"abstract":"<p><strong>Background: </strong>In some patients who receive a cardiac resynchronization therapy (CRT) device, the left ventricular ejection fraction (LVEF) does not improve.</p><p><strong>Methods: </strong>We analyzed patients enrolled in the REVERSE, MADIT-CRT, and BLOCK-HF trials, restricting the analysis to those who received CRT. Characteristics of patients with or without improved LVEF were compared using two sample t-tests and Pearson's chi-square tests. Kaplan-Meier survival curves were constructed to display time-to-event data. A log-rank test was used to compare event rates for patients with or without improved LVEF. Mixed effects Cox Proportional-Hazards models adjusting for covariates were used to analyze time to death or heart failure hospitalization (HFH) and time to death.</p><p><strong>Results: </strong>Of 1065 included patients, 75% (802) were men, 87% (793) were White, 11% (118) were Black, and 7% (72) were Hispanic. LVEF improved in 910 (85%) patients and did not in 155 (15%). Patients with an improved LVEF were less likely to have ischemic cardiomyopathy (ICM) (54% vs 76%; p = 0.004), more likely to have LBBB (73% vs 53%; p = < 0.001), and had longer QRS duration (159 vs 150 ms; p = < 0.001). In adjusted analyses, improved LVEF was associated with a longer time to HFH or death (HR 0.40; 95% CI 0.26-0.62; p < 0.001) or death alone (HR 0.27; 95% CI 0.15-0.48; p < 0.001).</p><p><strong>Conclusions: </strong>Patients with improvement in LVEF post-CRT implantation are less likely to have ICM and more likely to have LBBB and a longer QRS interval. Improvement in LVEF was associated with better outcomes.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1555-1562"},"PeriodicalIF":2.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12354237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new score with superior stroke risk prediction in atrial fibrillation: entropy-based information gain approaches in a large nationwide cohort. 一个新的评分与优越的卒中风险预测心房颤动:基于熵的信息获取方法在一个大的全国队列。
IF 2.7 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-05-14 DOI: 10.1007/s10840-025-02053-4
Emre Oto, Sercan Okutucu, Deniz Katircioglu Öztürk, Naim Ata, Bunyamin Yavuz, Chris Gale, A John Camm, Karen S Pieper, Ajay K Kakkar, Ali Oto
{"title":"A new score with superior stroke risk prediction in atrial fibrillation: entropy-based information gain approaches in a large nationwide cohort.","authors":"Emre Oto, Sercan Okutucu, Deniz Katircioglu Öztürk, Naim Ata, Bunyamin Yavuz, Chris Gale, A John Camm, Karen S Pieper, Ajay K Kakkar, Ali Oto","doi":"10.1007/s10840-025-02053-4","DOIUrl":"10.1007/s10840-025-02053-4","url":null,"abstract":"<p><strong>Background: </strong>Risk scores have been used to assess stroke risk in atrial fibrillation (AF) for reducing ischemic stroke and bleeding risk. Information gain ratio (IGR) is an entropy-based parameter that shows which clinical score is more informative for prediction of the clinical endpoint.</p><p><strong>Objective: </strong>Herein, we aimed to generate and validate a stroke risk score based on the TuRkish Atrial Fibrillation (TRAF) data.</p><p><strong>Methods: </strong>We used a split-sample approach to develop and internally validate the new stroke risk score. Based on multivariate logistic regression analysis, we generated CHADS-F in the anticoagulation naïve TRAF cohort (274,631 patients). CHADS-F stands for Cardiac failure (1 point), hypertension (1 point), age (≥ 65-69 = 1 point, ≥ 70-74 = 2 points ≥ 75 = 3 points), diabetes (1 point), stroke (2 points), and older female (1 point) (≥ 65). External validation was performed in the \"Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF)\" Registry. Informative capacity and accuracy of the CHADS-F score was compared with CHADS<sub>2</sub> and CHA<sub>2</sub>DS<sub>2</sub>-VASc scores.</p><p><strong>Results: </strong>In anticoagulation naïve cohort, CHADS-F (IGR for all cohort: 0.7526) outperforms both the CHADS<sub>2</sub> (IGR for all cohort: 0.6340) and CHA<sub>2</sub>DS<sub>2</sub>-VASc (IGR for all cohort: 0.6969) in terms of the IGR for ischemic stroke and systemic embolism. Receiver operating characteristic curves revealed highest accuracy for the CHADS-F score [area under curve for CHADS-F: 0.743, CHADS<sub>2</sub>: 0.722, and CHA<sub>2</sub>DS<sub>2</sub>-VASc: 0.722]. CHADS-F had good discriminative abilities at predicting clinical endpoints in the GARFIELD-AF registry.</p><p><strong>Conclusion: </strong>The CHADS-F score had higher informative capacity and accuracy than the current CHADS<sub>2</sub> and CHA<sub>2</sub>DS<sub>2</sub>-VASc scores for predicting stroke and systemic embolism.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1739-1748"},"PeriodicalIF":2.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term follow up of single-chamber atrial pacing-system upgrade and Wenckebach block point behavior: potential implications for leadless AAI pacing? 单室心房起搏系统升级和Wenckebach阻滞点行为的长期随访:对无导联心房起搏的潜在影响?
IF 2.6 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-05-16 DOI: 10.1007/s10840-025-02061-4
Patrick Badertscher, Rebecca Arnet, Corinne Isenegger, Behnam Subin, Sven Knecht, Jessica Trussardi, Philipp Krisai, Felix Mahfoud, Christian Sticherling, Beat Schär, Michael Kühne
{"title":"Long-term follow up of single-chamber atrial pacing-system upgrade and Wenckebach block point behavior: potential implications for leadless AAI pacing?","authors":"Patrick Badertscher, Rebecca Arnet, Corinne Isenegger, Behnam Subin, Sven Knecht, Jessica Trussardi, Philipp Krisai, Felix Mahfoud, Christian Sticherling, Beat Schär, Michael Kühne","doi":"10.1007/s10840-025-02061-4","DOIUrl":"10.1007/s10840-025-02061-4","url":null,"abstract":"<p><strong>Background: </strong>Single chamber atrial pacing (AAI) provides a disease-specific treatment for sick sinus syndrome (SSS) but has largely been replaced by DDD pacing. With the advent of leadless atrial pacemakers (PM), there is growing interest in long-term follow-up data in patients with SSS and an AAI pacemaker.</p><p><strong>Purpose: </strong>To assess the incidence of system upgrade in patients treated with AAI-PM for SSS during long-term follow-up.</p><p><strong>Methods: </strong>This is an analysis of prospectively enrolled patients undergoing implantation of an AAI-PM. Wenckebach block point (WBP) was measured at implantation and serially during follow up.</p><p><strong>Results: </strong>We included 178 patients (58% female, median age at implantation 77 [71-83] years). The median follow-up duration was 6.5 [2.0-9.7] years. Twenty-three patients (13%) received a system upgrade to a DDD system, corresponding to a yearly upgrade rate of 2.0%. Median time to system upgrade was 5.2 [1.6-8.7] years. Reasons for system upgrade were higher-degree AVB (39%), atrial arrhythmias (35%), low WBP (17%), and syncope (9%). Median WBP at implantation was 130 [120-140] bpm, showing a significant decline over time in the upgrade-group compared to the rest of the cohort with 103 [91-130] bpm vs. 130 [120-130] bpm (p = 0.011).</p><p><strong>Conclusion: </strong>In this cohort of patients undergoing AAI-PM implantation for SSS, upgrade to a DDD system was low during long-term follow-up. Therefore, AAI pacing for the treatment of SSS may be considered a patient-tailored treatment option, especially in light of novel leadless pacing therapies.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1605-1612"},"PeriodicalIF":2.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unintended isolation of the left atrial appendage: a rare complication of pulsed-field ablation. 意外分离左心耳:脉冲场消融的罕见并发症。
IF 2.7 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-04-26 DOI: 10.1007/s10840-025-02055-2
Yuki Takai, Yuya Nakamura, Taku Asano, Toshiro Shinke
{"title":"Unintended isolation of the left atrial appendage: a rare complication of pulsed-field ablation.","authors":"Yuki Takai, Yuya Nakamura, Taku Asano, Toshiro Shinke","doi":"10.1007/s10840-025-02055-2","DOIUrl":"10.1007/s10840-025-02055-2","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1549-1550"},"PeriodicalIF":2.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrial septal pouch as the main cause of failed transseptal puncture in pulmonary vein isolation. 房间隔袋是肺静脉隔离术中经间隔穿刺失败的主要原因。
IF 2.7 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-05-13 DOI: 10.1007/s10840-025-02067-y
José Andrés Del Valle-Montero, Irene Esteve-Ruiz, María Teresa Moraleda-Salas, Pablo Moriña-Vázquez, Ana José Manovel-Sánchez, Antonio Enrique Gómez-Menchero
{"title":"Atrial septal pouch as the main cause of failed transseptal puncture in pulmonary vein isolation.","authors":"José Andrés Del Valle-Montero, Irene Esteve-Ruiz, María Teresa Moraleda-Salas, Pablo Moriña-Vázquez, Ana José Manovel-Sánchez, Antonio Enrique Gómez-Menchero","doi":"10.1007/s10840-025-02067-y","DOIUrl":"10.1007/s10840-025-02067-y","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1551-1552"},"PeriodicalIF":2.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative cardiac magnetic resonance standardized signal intensity comparison in dilated cardiomyopathy vs. cardiac sarcoidosis. 扩张型心肌病与心脏结节病定量心脏磁共振标准化信号强度比较。
IF 2.6 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-05-06 DOI: 10.1007/s10840-025-02042-7
Ting-Wei Ernie Liao, Lingyu Xu, Mirmilad Pourmousavi Khoshknab, Paul J Mather, Paco E Bravo, Benoit Desjardins, Saman Nazarian
{"title":"Quantitative cardiac magnetic resonance standardized signal intensity comparison in dilated cardiomyopathy vs. cardiac sarcoidosis.","authors":"Ting-Wei Ernie Liao, Lingyu Xu, Mirmilad Pourmousavi Khoshknab, Paul J Mather, Paco E Bravo, Benoit Desjardins, Saman Nazarian","doi":"10.1007/s10840-025-02042-7","DOIUrl":"10.1007/s10840-025-02042-7","url":null,"abstract":"<p><strong>Background: </strong>Dilated cardiomyopathy (DCM) and cardiac sarcoidosis (CS) manifest unique late gadolinium enhancement (LGE) patterns on cardiac magnetic resonance (CMR), indicative of different myocardial scar distributions. However, the overlap in these patterns due to their lack of specificity complicates differentiation. This study introduces a novel quantitative method employing z-score analysis of LGE-CMR intensity to objectively compare the spatial distribution of LGE intensity between DCM and CS.</p><p><strong>Methods: </strong>This retrospective study included 22 NICM patients (13 DCM, 9 CS) who underwent CMR before electrophysiology study from November 2018 to May 2023. LGE images were delineated into sub-endocardial, mid-myocardial, and sub-epicardial layers across anterior, lateral, inferior, and septal walls using the AHA 17-segment model. CMR signal intensities were standardized to z-scores (z = (x - μ)/σ), with x as the signal intensity for a specific myocardial segment, and μ and σ as the mean and SD for all LV myocardial segments, to map regional intensity variations.</p><p><strong>Results: </strong>Compared to DCM, CS patients exhibited significantly higher CMR signal intensity z-scores in the septum (β = 0.32, p = 0.009), particularly in the endocardial third of the right ventricular (RV) side (β = 0.56, p = 0.001). A z-score greater than 0.40 in this area was associated with a CS diagnosis, with an area under the ROC curve of 0.692 in fivefold cross-validation.</p><p><strong>Conclusion: </strong>Patients with CS exhibit higher affinity for contrast in the septum, particularly on the RV endocardium. Standardized analysis of CMR signal intensities provides a novel, quantitative method for distinguishing CS from DCM, with the former exhibiting higher CMR signal intensity z-scores in the septum.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1593-1604"},"PeriodicalIF":2.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative skin antiseptics for the prevention of cardiac implantable electronic device infections: chlorhexidine-alcohol versus povidone-iodine-alcohol. 术前皮肤防腐剂预防心脏植入式电子装置感染:氯己定-酒精与聚维酮-碘-酒精。
IF 2.7 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-04-16 DOI: 10.1007/s10840-025-02049-0
Antoine Da Costa, Lucas Ovache, Sarah Chellali, Jean Baptiste Guichard, Cécile Romeyer, Cedric Yvorel, Karim Benali
{"title":"Preoperative skin antiseptics for the prevention of cardiac implantable electronic device infections: chlorhexidine-alcohol versus povidone-iodine-alcohol.","authors":"Antoine Da Costa, Lucas Ovache, Sarah Chellali, Jean Baptiste Guichard, Cécile Romeyer, Cedric Yvorel, Karim Benali","doi":"10.1007/s10840-025-02049-0","DOIUrl":"10.1007/s10840-025-02049-0","url":null,"abstract":"<p><strong>Background: </strong>Skin antisepsis plays a key role in the prevention of cardiac implantable electronic device (CIED) infections. Moreover, skin antisepsis by chlorhexidine-alcohol has not yet been fully evaluated.</p><p><strong>Objectives: </strong>This single-center controlled study sought (1) to conduct a prospective observational analysis comparing two antiseptic skin preparations over two similar consecutive time periods, one conducted over a 1-year period using a povidone-iodine-alcohol solution (group I) and the other over the following year with a chlorhexidine-alcohol solution (group II) and (2) to determine real-life CIED infection predictive factors using the Prevention of Arrhythmia Device Infection Trial (PADIT) score.</p><p><strong>Methods and results: </strong>CIED implantations were performed in 1689 patients. A total of 17 patients (1.01%) developed a CIED infection. Long-term follow-up (16 ± 13 months) revealed no significant differences between groups: infections were observed in 9/844 patients (1.07%) in group I versus 8/845 patients (0.95%) in group II (p = 0.99). Univariate and multivariate logistic regression analyses were performed to identify infectious risk factors. Adjusted odds ratios (ORs) and hazard ratios (HRs) were calculated. Univariate analyses revealed that infection occurrence was positively correlated with acute heart failure (OR: 3.55; 95%CI [1.24-9.37]; p = 0.01 and HR: 3.37; 95% CI [1.28-8.87]; p = 0.014), renal failure (OR: 2.71; 95% CI [0.88-8.42]; p = 0.08 and HR: 2.99; 95% CI [0.97-9.17]; p = 0.05), use of temporary pacing before the implantation procedure (OR: 4.45; 95% CI [1.003-20.3]; p = 0.04 and HR: 4.35; 95% CI [0.99-19.05]; p = 0.05), PADIT score (OR: 1.3; 95% CI [1.064-1.54]; p = 0.009 and HR: 1.27; 95% CI [1.052-1.53]; p = 0.013), and PADIT score ≥ 5 (OR: 4.185; 95% CI [1.6-10.9]; p = 0.003 and HR: 3.91; 95% CI [1.51-10.149]; p = 0.005). No clear significant difference was found regarding the antiseptic skin preparation choice (OR: 0.88; 95% CI [0.34-2.3]; p = 0.8 and HR: 1.11; 95% CI [0.416-2.98]; p = 0.82). In multivariate analysis, the PADIT score ≥ 5 (OR: 3.18; 95% CI [1.125-8.99]; p = 0.003 and HR: 3.052; 95% CI [1.089-8.55]; p = 0.034) and use of temporary pacing before the implantation procedure (OR: 8.44; 95% CI [1.68-42.34]; p = 0.01 and HR: 8.49; 95% CI [1.732-41.69]; p = 0.008) were negatively correlated with the device infection risk.</p><p><strong>Conclusion: </strong>This study found that chlorhexidine-alcohol and povidone-iodine-alcohol solutions displayed similar antiseptic effects regarding CIED infection prevention. Both use of temporary pacing before the implantation procedure and PADIT score ≥ 5 correlated with the device infection risk.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1563-1572"},"PeriodicalIF":2.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of pacing-induced cardiomyopathy: left bundle branch area pacing versus leadless pacing. 起搏诱发心肌病的发生率:左束支区起搏与无导联起搏。
IF 2.7 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-04-21 DOI: 10.1007/s10840-025-02048-1
Maya Chopra, Ji-Cheng Hsieh, William Mueller, Eric D Braunstein, Stuart Beldner, Raman L Mitra, Laurence M Epstein, Jonathan Willner, James K Gabriels
{"title":"Incidence of pacing-induced cardiomyopathy: left bundle branch area pacing versus leadless pacing.","authors":"Maya Chopra, Ji-Cheng Hsieh, William Mueller, Eric D Braunstein, Stuart Beldner, Raman L Mitra, Laurence M Epstein, Jonathan Willner, James K Gabriels","doi":"10.1007/s10840-025-02048-1","DOIUrl":"10.1007/s10840-025-02048-1","url":null,"abstract":"<p><strong>Background: </strong>Patients with chronic right ventricular (RV) pacing are at risk for developing pacing-induced cardiomyopathy (PICM). Data regarding the incidence of PICM when pacing the RV septum using a leadless pacemaker (LP) are limited. Left bundle branch area pacing (LBBAP) has emerged as a viable alternative to RV pacing with a low incidence of PICM.</p><p><strong>Methods: </strong>All patients who received either a LP capable of providing atrioventricular (AV) synchronous pacing or a permanent pacemaker (PPM) with a LBBAP lead (lumenless or stylet-driven leads) for AV block between January 2021 and January 2023 at a single center were screened. Patients were included in the final analysis if they had both a pre- and post-operative transthoracic echocardiogram, pre- and post-operative electrocardiograms, and a pacing burden of ≥ 20%. The incidence of PICM, defined as a decrease in the left ventricular ejection fraction (LVEF) by ≥ 20% and to a value < 50% after a follow-up of at least six months, was compared between LBBAP and LP groups.</p><p><strong>Results: </strong>Over the study period, 533 PPMs were implanted for AV block. Of these, 95 patients met the inclusion criteria; 70 underwent LBBAP and 25 received LPs. The average age of the population was 75 ± 13 years; 64 (63%) were men. There was no difference in the mean pre-operative LVEF (57% ± 16% vs. 61% ± 10%; p = 0.25) or QRS duration (123 ± 33ms vs. 130 ± 29ms) between the LBBAP and LP groups. There was a high burden of ventricular pacing in both groups (90% ± 19% vs. 92% ± 13%; p = 0.52). After a follow-up of 14 ± 8 months, the incidence of PICM was significantly lower in the LBBAP group compared to the LP group (4.3% vs. 24%; p = 0.0039).</p><p><strong>Conclusion: </strong>In patients who are not candidates for cardiac resynchronization, who require a high burden of ventricular pacing, LBBAP may lead to a lower incidence of PICM than right ventricular septal pacing with a LP.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1585-1592"},"PeriodicalIF":2.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integration of automated peak frequency annotation with voltage mapping for identifying ventricular tachycardia ablation sites. 自动化峰值频率注释与电压映射的集成,用于识别室性心动过速消融部位。
IF 2.7 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-04-16 DOI: 10.1007/s10840-025-02045-4
Sukriye Ebru Onder, Tumer Erdem Guler, Serdar Bozyel, Metin Cagdas, Sadiye Nur Dalgic, Abdulcebbar Sipal, Samet Gecer, Emre Kılıc, Pasquale Santangeli, Tolga Aksu
{"title":"Integration of automated peak frequency annotation with voltage mapping for identifying ventricular tachycardia ablation sites.","authors":"Sukriye Ebru Onder, Tumer Erdem Guler, Serdar Bozyel, Metin Cagdas, Sadiye Nur Dalgic, Abdulcebbar Sipal, Samet Gecer, Emre Kılıc, Pasquale Santangeli, Tolga Aksu","doi":"10.1007/s10840-025-02045-4","DOIUrl":"10.1007/s10840-025-02045-4","url":null,"abstract":"<p><strong>Background: </strong>Peak frequency (PF) analysis has emerged as a novel tool for identifying arrhythmogenic substrates in ventricular tachycardia (VT) ablation, particularly when combined with traditional substrate mapping techniques such as voltage mapping and Isochronal Late Activation Mapping (ILAM). This study evaluates the utility of PF analysis in scarred myocardial regions, with a focus on areas containing manually annotated late potentials (LPs).</p><p><strong>Methods: </strong>Electroanatomical mapping using the EnSite X™ system was performed in 20 patients undergoing VT ablation. PF analysis was applied to scarred regions with voltages < 1.5 mV, with and without LPs, to identify zones of high-frequency activity. PF zones (PFZs) were compared to voltage maps and ILAM to assess spatial correlation with deceleration zones (DZs) and their role in defining ablation targets.</p><p><strong>Results: </strong>Peak frequency distributions differed significantly across myocardium conditions (H = 254.92, p < 0.0001). The median peak frequency was 120.0 Hz (77.3-179.0 Hz) in normal voltage myocardium, 145.0 Hz (100.0-194.3 Hz) in low-voltage myocardium without LPs, and 291.0 Hz (190.3-380.3 Hz) in low-voltage myocardium with LPs. Pairwise comparisons showed significant differences: normal voltage vs. low voltage without LPs (U = 46,455.0; p = 0.0019), normal voltage vs. low voltage with LPs (U = 20,935.5; p < 0.0001), and low voltage without LPs vs. low voltage with LPs (U = 19,548.0; p < 0.0001). PFZs exhibited strong colocalization with DZs identified via ILAM, with > 50% spatial overlap in most cases. The automated peak frequency annotation algorithm demonstrated high reproducibility, significantly reducing operator dependency compared to manual annotation.</p><p><strong>Conclusion: </strong>PF analysis provides a robust and reproducible method for identifying arrhythmogenic substrates in VT ablation. When integrated with voltage mapping and ILAM, it facilitates precise localization of critical ablation targets, particularly in regions with LPs. These findings highlight the potential of PF analysis to enhance the efficacy of substrate-based ablation strategies.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1573-1583"},"PeriodicalIF":2.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrograde coronary venous ethanol infusion for ablation of a LVOT TAVR-related ventricular tachycardia. 逆行冠状静脉乙醇灌注消融LVOT tavr相关室性心动过速。
IF 2.7 4区 医学
Journal of Interventional Cardiac Electrophysiology Pub Date : 2025-11-01 Epub Date: 2025-05-14 DOI: 10.1007/s10840-025-02062-3
Agustín Bortone, Caroline Hébert, Victor-Xavier Tadros, Walid Ghodhbane, Eric Maupas
{"title":"Retrograde coronary venous ethanol infusion for ablation of a LVOT TAVR-related ventricular tachycardia.","authors":"Agustín Bortone, Caroline Hébert, Victor-Xavier Tadros, Walid Ghodhbane, Eric Maupas","doi":"10.1007/s10840-025-02062-3","DOIUrl":"10.1007/s10840-025-02062-3","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1553-1554"},"PeriodicalIF":2.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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