Journal of Infection Prevention最新文献

{"title":"<i>Mycobacterium tuberculosis</i> infection and disease in healthcare workers in a tertiary referral hospital in Bandung, Indonesia.","authors":"Lika Apriani,&nbsp;Susan McAllister,&nbsp;Katrina Sharples,&nbsp;Isni Nurul Aini,&nbsp;Hanifah Nurhasanah,&nbsp;Rovina Ruslami,&nbsp;Dick Menzies,&nbsp;Philip C Hill,&nbsp;Bachti Alisjahbana","doi":"10.1177/17571774211046887","DOIUrl":"https://doi.org/10.1177/17571774211046887","url":null,"abstract":"<p><strong>Background: </strong>Healthcare workers (HCWs), especially in high tuberculosis (TB) incidence countries, are at risk of <i>Mycobacterium tuberculosis</i> infection and TB disease, likely due to greater exposure to TB cases and variable implementation of infection control measures.</p><p><strong>Aim: </strong>We aimed to estimate the prevalence of tuberculin skin test (TST) positivity, history of TB and to identify associated risk factors in HCWs employed at a tertiary referral hospital in Bandung, Indonesia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from April to August 2018. A stratified sample of the HCWs were recruited, screened by TST, assessed for TB symptoms, history of TB disease and possible risk factors. Prevalence of positive TST included diagnosis with TB after starting work. HCWs with TB disease diagnosed earlier were excluded. Survey weights were used for all analyses. Possible risk factors were examined using logistic regression; adjusted odds ratios and 95% confidence intervals (CI) are presented.</p><p><strong>Results: </strong>Of 455 HCWs recruited, 42 reported a history of TB disease (25 after starting work) and 395 had a TST result. The prevalence of positive TST was 76.9% (95% CI 72.6-80.8%). The odds increased by 7% per year at work (95% CI 3-11%) on average, with a rapid rise in TST positivity up to 10 years of work and then a plateau with around 80% positive.</p><p><strong>Discussion: </strong>A high proportion of HCWs had a history of TB or were TST positive, increasing with longer duration of work. A package of TB infection control measures is needed to protect HCWs from <i>Mycobacterium tuberculosis</i> infection.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"23 4","pages":"155-166"},"PeriodicalIF":1.2,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8c/62/10.1177_17571774211046887.PMC10226060.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10298409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of hygienic clinical attire for doctors during COVID-19: A university hospital experience.","authors":"Hannah James,&nbsp;Andrew Phillips","doi":"10.1177/17571774211046989","DOIUrl":"https://doi.org/10.1177/17571774211046989","url":null,"abstract":"Personal protective equipment (PPE) for healthcare staff has been central to reducing nosocomial transmission of COVID-19 (Public Health England, 2020: p6–36). The role of doctors’ clinical attire in transmitting the virus in hospital settings has not been reported in the literature. The survival of SARS-CoV-2 on clothing is currently unknown, but the virus has been shown to remain viable and infectious on surfaces for several days, depending on inoculum shed (Doremalen et al., 2020). Fomite transmission was associated with nosocomial spread and super-spreading events with SARS-CoV-1, and the stability of the two viruses has been demonstrated to be similar (Chen et al., 2004). In contrast to nursing and allied healthcare staff who have an established uniform policy with evidence-based hygiene measures (NHS England and NHS Improvement, 2020:p2– 6), doctors habitually commute to the hospital in work clothing and visit public places en route (Oxtoby, 2015). This is poor infection control practice in ordinary times, but in the context of a pandemic may represent an underappreciated route of viral transmission. We report the experience of piloting hygienic ‘ward wear’ scrubs for doctors at a large 1000-bed National Health Service University teaching hospital. The hospital employs 1022 doctors, all of whom were offered use of the new scrubs on a loan basis during the first wave of the UK COVID-19 pandemic in March 2020. The provision consisted of three sets of a unisex navy blue poly-cotton scrub suit of standard design, with the hospital logo and ‘doctor’ embroidered on the chest. Doctors were responsible for laundering their own scrubs, as evidence shows that domestic laundering at 60°C is as effective as commercial washing for decontaminating healthcare clothing (NHS England and NHS Improvement, 2020:p2–6). Doctors using the scrubs were instructed to change into and out of them on hospital premises using existing changing room facilities and store their clothing with their personal belongings. Data was obtained by a web survey with 10 questions in October 2020. Questions included multiple choice, Likert scale questions and free-text. All doctors employed at the hospital (n = 1022) were invited by email to take part. The objectives were to map the demographics of uptake of the ward wear initiative; to obtain feedback on users’ perceptions of hygiene, comfort and professionalism; and to understand the barriers to use among doctors who chose not to take part in the pilot. Of 1022 doctors, 504 (49%) opted to use the new scrubs. 169 doctors completed the survey (14%). 135 (80%) of respondents were using the new scrubs at the time of the survey, 6 months after the start of the initiative. There was an equal gender split amongst respondents who had tried the scrubs (the ‘uptake’ group) and those who chose not to (the ‘decline’ group). The grade of respondents was comparable between the uptake and decline groups and broadly representative of the proportions","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"23 4","pages":"190-191"},"PeriodicalIF":1.2,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006087/pdf/10.1177_17571774211046989.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9540229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection prevention and control strategies against carbapenem resistant Enterobacteriaceae - a systematic review.","authors":"Catarina Santos-Marques,&nbsp;Helena Ferreira,&nbsp;Sónia Gonçalves Pereira","doi":"10.1177/17571774211066762","DOIUrl":"https://doi.org/10.1177/17571774211066762","url":null,"abstract":"<p><strong>Background: </strong>Antimicrobial resistance is exponentially worsening, and the spread of prevalent carbapenem resistant Enterobacteriaceae (CRE) is a major contributor to this global concern. Infection prevention and control strategies are increasingly consolidated key tools to control this worldwide problem.</p><p><strong>Aim: </strong>To identify, collect and analyse available evidence regarding the impact of infection prevention and control strategies on prevalent CRE dissemination.</p><p><strong>Methods: </strong>Pubmed®, Scopus® and Web of Science® were searched systematically for articles published between 1th January 2017 and 30th June 2020, guided by the research question 'What are the most effective and efficient strategies to prevent and control infection/colonisation caused by Carbapenem resistant <i>Escherichia coli</i> and Carbapenem resistant <i>Klebsiella pneumoniae</i>?'.</p><p><strong>Findings: </strong>Eleven thousand six hundred and thirty-five publications were found, but after applying the inclusion and exclusion criteria, only 30 were selected. The majority of reviewed studies (<i>n</i> = 24) were performed in outbreak situations, 26 studies occurred in acute care units and of those, 17 in intensive care units . From the set of implemented infection prevention and control measures, in 29 studies surveillance cultures were applied, in 23 studies patients were isolated or cohorted and, in general, all described the implementation of standard and contact precaution measures.</p><p><strong>Conclusion: </strong>This systematic review underlines the importance of infection prevention and control strategies in CRE dissemination, standing out the need of further studies outside outbreak and intensive care units contexts. Investment increments and training and educating of all involved are also important contributors to shift this problem, but still with relevant gaps in their implementation, in all types of care units, that need to be addressed.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"23 4","pages":"167-185"},"PeriodicalIF":1.2,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226056/pdf/10.1177_17571774211066762.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10298411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancement of infection prevention case review process to optimize learning from defects.","authors":"Staci S Reynolds,&nbsp;Christopher Sova,&nbsp;Halie Lozano,&nbsp;Kalpana Bhandari,&nbsp;Bonnie Taylor,&nbsp;Erica Lobaugh-Jin,&nbsp;Charlene Carriker,&nbsp;Sarah S Lewis,&nbsp;Becky A Smith,&nbsp;Ibukunoluwa C Kalu","doi":"10.1177/17571774211066760","DOIUrl":"https://doi.org/10.1177/17571774211066760","url":null,"abstract":"<p><p>Hospitals continue to struggle with preventable healthcare-associated infections. Whereas the focus is generally on proactive prevention processes, performing retrospective case reviews of infections can identify opportunities for quality improvement and maximize learning from defects. This brief article provides practical information for structuring the case review process using readily available health system platforms. Using a structured approach for case reviews can help identify trends and opportunities for improvement.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"23 3","pages":"120-124"},"PeriodicalIF":1.2,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052852/pdf/10.1177_17571774211066760.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9733108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between coronavirus disease morbidity and mortality rates and BCG vaccination policies in OECD countries. Authors' reply.","authors":"Yuki Senoo,&nbsp;Yousuke Suzuki,&nbsp;Kenji Tsuda,&nbsp;Tetsuya Tanimoto,&nbsp;Kenzo Takahashi","doi":"10.1177/17571774211066753","DOIUrl":"https://doi.org/10.1177/17571774211066753","url":null,"abstract":"<p><p>We appreciate the reviewer's comment to our article on the correlation between the national BCG vaccination policy and coronavirus disease 2019 among Organisation for Economic Co-operation and Development countries as of April 20, 2020. In this letter, we further updated the data up to November 1, 2020, and found that the updated results also arrive at the similar conclusion as the accepted article.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"23 3","pages":"118-119"},"PeriodicalIF":1.2,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052849/pdf/10.1177_17571774211066753.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9733112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of behaviour change theory for infection prevention and control practices in healthcare settings: A scoping review.","authors":"Carolynn Greene, Jennie Wilson","doi":"10.1177/17571774211066779","DOIUrl":"10.1177/17571774211066779","url":null,"abstract":"<p><strong>Background: </strong>Infection prevention and control (IPC) practices performed by healthcare workers are key to the prevention and management of infections. Compliance with IPC practices is often low, they are therefore commonly the focus of improvement interventions. Designing interventions that are based on behaviour change theories may help to improve compliance to practice. The aim of this review is to synthesise the evidence on the application of behaviour change theories to interventions to improve IPC practice in healthcare settings.</p><p><strong>Methods: </strong>A scoping review was conducted following the Joanna Briggs Institute methodological framework. The theories of focus were the Theoretical Domains Framework (TDF), Capability, Opportunity, Motivation, Behaviour (COM-B) and Behaviour Change Wheel (BCW). Studies which applied these theories to any IPC practice were included.</p><p><strong>Results: </strong>Eleven studies were identified which met the inclusion criteria. The IPC behaviours investigated were hand hygiene (7), antimicrobial stewardship (3), and MRSA screening (1). Nine studies explored barriers and facilitators to existing IPC practice; three used their findings to design a behaviour change intervention or tool. Domains of 'beliefs about consequences', 'environmental context/resources', and 'social/professional role and identity' were identified as key across all three IPC behaviours.</p><p><strong>Discussion: </strong>This review has demonstrated the use of behavioural theories to understand determinants of behaviour related to IPC practice. Currently, there are few published examples of interventions to improve IPC practice that have been underpinned by behavioural theory. Practitioners in IPC should consider the use of these methods to enhance the efficacy of strategies to change healthcare worker behaviour.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"68 1","pages":"108-117"},"PeriodicalIF":0.9,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76702354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diary.","authors":"","doi":"10.1177/17571774221090372","DOIUrl":"https://doi.org/10.1177/17571774221090372","url":null,"abstract":"","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"23 3","pages":"128"},"PeriodicalIF":1.2,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052846/pdf/10.1177_17571774221090372.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9733110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An intermittent outbreak of <i>Burkholderia cepacia</i> contaminating hematopoietic stem cells resulting in infusate-related blood stream infections.","authors":"Anis Raddaoui,&nbsp;Farah Ben Tanfous,&nbsp;Yosra Chebbi,&nbsp;Aymen Mabrouk,&nbsp;Wafa Achour","doi":"10.1177/17571774211066783","DOIUrl":"https://doi.org/10.1177/17571774211066783","url":null,"abstract":"<p><p>Microbial contamination of hematopoietic stem cells (HSC), used for autologous and allogenic transplantations, is rare but could cause serious blood stream infection in transplanted patients. These infections occur immediately, or later following the formation of biofilm on the catheter lumen. The present study describes an intermittent <i>B. cepacia</i> HSC contamination associated with nosocomial bacteremia: from October 2011 to April 2015, 17 <i>B. cepacia</i> strains were isolated in HSC bags (<i>n</i> = 14) and blood cultures (<i>n</i> = 3) in patients hospitalized in the National Bone Marrow Transplant Center. Two epidemiologic investigations in the National Blood Transfusion Center, allowing the isolation of three strains in hygiene samples, and four interventions in this institution were done. To identify the source of this contamination, a molecular investigation was done on 23 <i>B. cepacia</i> strains isolated in our center from 2007 to 2015. PFGE analysis revealed five clusters. The major cluster included 18 strains isolated from HSC bags (<i>n</i> = 14), blood culture (<i>n</i> = 1), and water cans and bath (<i>n</i> = 3). The second cluster (B) including only two and the remaining clusters (C, D, and E) contained single strains isolated before the epidemic period. These findings confirmed that the origin of the outbreak was the contaminated water used in the water bath during the thawing step of HSC bags. Based on this result, new sterile water was used for every defrosting, but HSC bags contamination persisted. In May 2015, the water bath was replaced with a dry bath and no <i>B. cepacia</i> strain was isolated from that date to April 2020.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"23 2","pages":"75-78"},"PeriodicalIF":1.2,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941591/pdf/10.1177_17571774211066783.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10868269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tuberculosis infection control measures and knowledge in primary health centres in Bandung, Indonesia.","authors":"Lika Apriani,&nbsp;Susan McAllister,&nbsp;Katrina Sharples,&nbsp;Hanifah Nurhasanah,&nbsp;Isni Nurul Aini,&nbsp;Nopi Susilawati,&nbsp;Rovina Ruslami,&nbsp;Bachti Alisjahbana,&nbsp;Dick Menzies,&nbsp;Philip C Hill","doi":"10.1177/17571774211046880","DOIUrl":"https://doi.org/10.1177/17571774211046880","url":null,"abstract":"<p><strong>Background: </strong>Health care workers (HCWs) in low- and middle-income countries (LMICs) continue to have an unacceptably high prevalence and incidence of <i>Mycobacterium tuberculosis</i> infection due to high exposure to tuberculosis (TB) cases at health care facilities and often inadequate infection control measures. This can contribute to an increased risk of transmission not only to HCWs themselves but also to patients and the general population.</p><p><strong>Aim: </strong>We assessed implementation of TB infection control measures in primary health centres (PHCs) in Bandung, Indonesia, and TB knowledge among HCWs.</p><p><strong>Methods: </strong>A cross-sectional study was conducted between May and November 2017 amongst a stratified sample of the PHCs, and their HCWs, that manage TB patients in Bandung<b>.</b> Questionnaires were used to assess TB infection control measures plus HCW knowledge. Summary statistics, linear regression and the Kruskal-Wallis test were used for analysis.</p><p><strong>Results: </strong>The median number of TB infection control measures implemented in 24 PHCs was 21 of 41 assessed. Only one of five management controls was implemented, 15 of 24 administrative controls, three of nine environmental controls and one of three personal respiratory protection controls. PHCs with TB laboratory facilities and high TB case numbers were more likely to implement TB infection control measures than other PHCs (<i>p</i>=0.003). In 398 HCWs, the median number of correct responses for knowledge was 10 (IQR 9-11) out of 11.</p><p><strong>Discussion: </strong>HCWs had good TB knowledge. TB infection control measures were generally not implemented and need to be strengthened in PHCs to reduce <i>M. tuberculosis</i> transmission to HCWs, patients and visitors.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"23 2","pages":"49-58"},"PeriodicalIF":1.2,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941593/pdf/10.1177_17571774211046880.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10868275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compliance to hand hygiene and its determinant factors among Community Health Care Providers in Community Clinics: an observational study in Bangladesh.","authors":"Md Hafizur Rahman,&nbsp;Md Nazmul Hassan,&nbsp;Md Shafiqul Islam Khan,&nbsp;Md Hasanuzzaman,&nbsp;Nurullah Awal","doi":"10.1177/17571774211066965","DOIUrl":"https://doi.org/10.1177/17571774211066965","url":null,"abstract":"<p><strong>Background: </strong>Healthcare-associated infections caused by poor hand hygiene (HH) practices can affect both the care seekers and the health care providers (HCPs) while providing primary health care. No study has been conducted on the compliance of HH practices among the primary level HCPs in Bangladesh.</p><p><strong>Objective: </strong>The study aimed to assess the compliance rates of HH and its determinant factors among Community Health Care Providers (CHCPs) in Community Clinics (CC).</p><p><strong>Methods: </strong>A cross-sectional study was conducted from September 2019 to February 2020 among 150 randomly selected CHCPs with functional HH facilities in Patuakhali district, Bangladesh. Structured interviews and observation tools were used to collect data.</p><p><strong>Results: </strong>Good HH compliance among CHCPs was found to be 16.7% (95% CI: 11.3-21.3). Out of all 1218 possible HH opportunities, only 255 (20.9%) resulted in any HH action. Presence of 70% alcohol-based hand sanitiser at the point of care (aOR: 6.4, 95% CI: 1.1-38.3), HH training (aOR: 4.6, 95% CI: 1.1-18.9), displayed visual cues (aOR: 4.4, 95% CI: 1.1-17.7), knowledge about HH (aOR: 3.8, 95% CI: 1.1-13.6) and number of HH opportunities (aOR: 0.6, 95% CI: 0.4-0.8) were factors associated with HH compliance.</p><p><strong>Discussion: </strong>Overall HH compliance among CHCPs was relatively low. It was recommended to implement multimodal HH improvement strategies, including a continuous training program, supply of alcohol-based hand rub, reminder, provision of five moments of HH in the training modules and feedback on HH performance.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"23 2","pages":"67-74"},"PeriodicalIF":1.2,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941594/pdf/10.1177_17571774211066965.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10868270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}