Journal of Infection Prevention最新文献

{"title":"Protection motivation theory and infection-prevention behavior in nursing students across 26 Thai institutions: A cross-sectional study.","authors":"Suparpit Maneesakorn von Bormann, Kulrawee Wiwattanacheewin, Thongsouy Sitanon","doi":"10.1177/17571774261493091","DOIUrl":"https://doi.org/10.1177/17571774261493091","url":null,"abstract":"<p><strong>Background: </strong>While nursing students often possess strong theoretical knowledge of infection control, a gap exists between their understanding and actual preventive practices. This study explored the relationship between knowledge, preventive behaviors, and Protection Motivation Theory (PMT) components among nursing students, using COVID-19 as a representative model.</p><p><strong>Methods: </strong>A national cross-sectional study was conducted among 463 nursing students from 26 educational institutions in Thailand. Data were collected via validated online questionnaires and analyzed using descriptive statistics, Spearman correlation coefficients, and binary logistic regression.</p><p><strong>Results: </strong>Most participants were female (95.9%) with moderate-to-good knowledge (92.5%) and moderate protection motivation (81.6%). Despite this, 53.1% exhibited poor infection prevention behaviors. First-year students without clinical experience demonstrated significantly poorer behaviors compared to those with clinical exposure (<i>χ</i> ^<i>2</i> = 4.690, <i>df</i> = 1, <i>p</i> = .030). Knowledge did not significantly correlate with behavior (<i>r</i> = 0.026, <i>p</i> = .582). Protection motivation showed a weak correlation (<i>r</i> = 0.181, <i>p</i> = .001). Logistic regression identified perceived fear as the only significant predictor of preventive behavior (OR = 1.049, 95% CI [1.010, 1.089], <i>p</i> = .013).</p><p><strong>Discussion: </strong>Perceived fear, rather than knowledge, primarily drives preventive adherence. Nursing education should transition beyond knowledge-based curricula to focus on enhancing self-efficacy and positive motivation to mitigate fear and improve compliance with infection control protocols.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261493091"},"PeriodicalIF":1.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13677992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Saudi national prevention model for reduction of central-line-associated bloodstream infections: A single-center qualitative study.","authors":"Waleed Abdulmotalib Mazi, Muhammad Abdulrahman Halwani","doi":"10.1177/17571774261493285","DOIUrl":"10.1177/17571774261493285","url":null,"abstract":"<p><strong>Aim: </strong>Central-line catheterization is a routine but high-risk procedure in intensive care, with central-line-associated bloodstream (CLABSI) infections remaining a major contributor to patient morbidity, prolonged hospitalization, and increased healthcare costs. In response to nationally elevated CLABSI rates, the Saudi Ministry of Health introduced the \"<i>Go Green</i>\" Project and the CLABSI National Prevention Tool in 2022 to standardize and strengthen prevention practices.</p><p><strong>Objective: </strong>To evaluate the national prevention model in a tertiary adult intensive care unit.</p><p><strong>Methods: </strong>We conducted semi-structured interviews, direct observations, and document reviews with 29 stakeholders, including nurses, physicians, infection-prevention specialists, and administrators. The study identified two major themes. The first one, \"A practical strategy requires both professional human resources and sufficient medical supplies,\" comprised four codes: staffing, workload overload, competency, and medical supplies. The second theme, \"An administrative strategy requires both awareness and behavioral attitudes,\" was represented by four codes: \"<i>Go Green</i>,\" education and training, hands-off practices, and teamwork. While participants generally demonstrated strong foundational knowledge of CLABSI prevention, gaps remained among a minority.</p><p><strong>Results: </strong>Key barriers included nursing workforce shortages, inconsistent supply availability, and variable competency in ultrasound-guided catheter insertion. Stakeholders emphasized the need for continuous training, improved supply-chain reliability, and stronger interdisciplinary collaboration, alongside a sustained cultural commitment to infection-prevention practices.</p><p><strong>Significance and impact: </strong>Although the institution achieved national recognition for CLABSI reduction in 2022, long-term success will depend on maintaining adherence to best practices, addressing operational constraints, and ensuring ongoing competency development to meet future performance targets.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261493285"},"PeriodicalIF":1.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strengthening infection prevention education among undergraduate nursing students through a curriculum-integrated escape room intervention: A comparative cohort study.","authors":"Efthimia Spyrakou, Eleni Poulianou, Dimitroula Giankoula, Emanuela Cakaj, Triantafyllia Tsavdaroglou, Maria Zarokosta, Evmorfia Andreou, Aristotelis Papadimitriou, Flora Sourri, Sophia Kostourou, Theodoros Katsoulas, Maria Tseroni","doi":"10.1177/17571774261493042","DOIUrl":"10.1177/17571774261493042","url":null,"abstract":"<p><strong>Aim/objective: </strong>To examine whether a curriculum-integrated IPC escape room was associated with improved undergraduate nursing students' knowledge.</p><p><strong>Methods and results: </strong>This comparative cohort study included 318 fourth-semester nursing students in a control cohort (<i>n</i> = 163) and an intervention cohort (<i>n</i> = 155). The intervention cohort completed a mandatory escape room with a digital quiz and four hands-on stations. Knowledge was assessed using the same 40-item final examination. The intervention cohort achieved higher scores than controls (median 7.25 [interquartile range 2.25] vs 5.50 [interquartile range 1.25], <i>p</i> < 0.001). Significant improvements were observed in hand hygiene, preventive care bundles, outbreak investigation, and correct PPE doffing sequence (all <i>p</i> < 0.001), with large effects in key domains (r ≥ 0.50) and a smaller effect for outbreak investigation (r = 0.20). Student satisfaction was high.</p><p><strong>Discussion: </strong>Integrating an IPC escape room may strengthen knowledge acquisition in key IPC domains. Further work should examine retention and scalability.</p><p><strong>Significance and impact: </strong>Game-based learning may offer a useful educational strategy for reinforcing key IPC practices.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261493042"},"PeriodicalIF":1.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and self-reported infection prevention and control practices among community health extension workers in primary healthcare facilities in Southeast Nigeria.","authors":"Etiedu Christopher Ekara, Uju Maryanne Onuorah, Friday Anigor Nwelibe, Beluchi Denise Emma-Echiegu, Jennifer Amalachi Okolo, Chiamaka Patience Odo","doi":"10.1177/17571774261497951","DOIUrl":"https://doi.org/10.1177/17571774261497951","url":null,"abstract":"<p><strong>Aim/objectives: </strong>To assess the knowledge and practice of infection prevention and control (IPC) among community health extension workers (CHEWs) in primary healthcare facilities in Southeast Nigeria and examine the relationship between IPC knowledge and preventive practices.</p><p><strong>Methods and results: </strong>A cross-sectional study was conducted among 328 CHEWs in Ebonyi State, Southeast Nigeria, using a multistage sampling technique. Data were collected using a structured pre-tested questionnaire and analysed with IBM SPSS version 20. Descriptive statistics and chi-square tests were performed at <i>p</i> ≤ 0.05. Most respondents were female (53.7%) and had received previous IPC training (91.8%). Overall, 97.3% demonstrated good IPC knowledge. High compliance with IPC practices was reported, including hand hygiene (88.1%), consistent use of personal protective equipment (90.9%), safe injection practices (98.2%), and proper sharps disposal (95.4%). Significant associations were observed between IPC knowledge and all assessed preventive practices (<i>p</i> < 0.001).</p><p><strong>Discussion: </strong>The findings suggest high levels of IPC knowledge and self-reported compliance among CHEWs in primary healthcare settings. Regular training, workplace monitoring, and availability of IPC policies may have contributed to these outcomes. However, gaps in hand hygiene consistency and IPC supply availability indicate the need for sustained institutional support.</p><p><strong>Significance and impact: </strong>Strengthening continuous IPC training, supportive supervision, and access to essential IPC resources may improve frontline preparedness and reduce the risk of healthcare-associated infections in resource-limited primary healthcare settings.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261497951"},"PeriodicalIF":1.0,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13658626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular detection of <i>mecA</i> and <i>mecC-</i>Mediated MRSA nasal carriage among healthcare workers in a tertiary care hospital.","authors":"Ajay Yadav, Kalpana Chauhan, Ravi Pratap Singh, Anita Pandey","doi":"10.1177/17571774261497956","DOIUrl":"10.1177/17571774261497956","url":null,"abstract":"<p><strong>Background: </strong>Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) remains a major cause of healthcare-associated infections worldwide. Healthcare workers (HCWs) colonized with MRSA may act as reservoirs for transmission, contributing to hospital- and community-acquired infections. Early detection of MRSA carriage is essential for effective infection-prevention and control.</p><p><strong>Methodology: </strong>This cross-sectional study was conducted at a tertiary care hospital. A total of 407 HCWs were screened for MRSA colonization using anterior nasal swab specimens. <i>Staphylococcus aureus</i> was identified using standard microbiological techniques. Methicillin resistance was determined phenotypically by the cefoxitin disc diffusion method according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Genotypic confirmation was performed using real-time polymerase chain reaction (RT-PCR) to detect the <i>mecA</i> and <i>mecC</i> genes. MRSA carriers received 2% intranasal mupirocin followed by repeat screening.</p><p><strong>Results: </strong>Among 407 HCWs screened, 96 <i>S. aureus</i> isolates were recovered, of which 80 (83.3%) were phenotypically confirmed as MRSA. The overall MRSA nasal carriage rate was 19.65%, with the highest prevalence among interns (40.62%). Male gender was significantly associated with MRSA carriage (<i>p</i> < 0.05). Among the 80 MRSA isolates, <i>mecA</i> was detected in 55 (68.75%), including 30 (37.5%) co-harbouring <i>mecC</i>. No isolate carried <i>mecC</i> alone, while 25 (31.25%) lacked both genes. All carriers became culture-negative after decolonization.</p><p><strong>Conclusion: </strong>A substantial proportion of HCWs were colonized with MRSA, highlighting their role in nosocomial transmission. Combined phenotypic and genotypic methods improved MRSA detection. Routine surveillance, strict infection-control measures, and targeted decolonization are essential to reduce MRSA transmission.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261497956"},"PeriodicalIF":1.0,"publicationDate":"2026-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catheter-related bloodstream infection reduction using systematic training in a Portuguese tertiary care hospital.","authors":"Inês Carolino Gomes, Filipa Carvas Feliciano, Clara Carvalho, Catarina Conceição","doi":"10.1177/17571774261493081","DOIUrl":"https://doi.org/10.1177/17571774261493081","url":null,"abstract":"<p><p>Catheter-related bloodstream infections (CRBSI) are a major cause of morbidity, mortality, and increased healthcare costs among hospital-acquired infections. To reduce CRBSI, the Infection Prevention and Control and Antimicrobial Resistance Program (UL-PPCIRA) reviewed current guidelines and implemented an intensive training project for healthcare professionals. Following the publication of care bundles, cascade training was conducted for staff involved in central line insertion and maintenance. This study aimed to evaluate the impact of this continuous quality improvement project on CRBSI incidence in a tertiary hospital. Three consecutive periods of 2 years were analyzed: two before and one after implementation. CRBSI rates were 1.84, 1.68, and 0.65 per 1000 catheter-days in periods 1, 2, and 3, respectively. No significant difference was observed between periods 1 and 2 (IRR 0.92, 95% CI 0.52-1.63). In contrast, period 3 showed a significant reduction compared to period 2 (IRR 0.35, 95% CI 0.14-0.78; <i>p</i> = .02). The implementation of standardized care bundles, supported by structured training, was associated with a significant reduction in CRBSI. Ongoing monitoring and reinforcement strategies are essential to ensure long-term sustainability.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261493081"},"PeriodicalIF":1.0,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13654005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and pilot evaluation of a long-stay patient infection prevention and control risk stratification tool: A single-centre service evaluation.","authors":"Harmony Owhotake, Michelle Bonney-Wheate, Jossy Ashlin, Stefano Oggiano, Aiden J Plant","doi":"10.1177/17571774261495775","DOIUrl":"10.1177/17571774261495775","url":null,"abstract":"<p><strong>Background: </strong>Long-stay inpatients accumulate modifiable healthcare-associated infection (HCAI) risks. Structured infection prevention and control (IPC) review processes specifically targeting these risks in long-stay inpatients are uncommon.</p><p><strong>Aim: </strong>To evaluate the feasibility of a structured long-stay patient IPC review tool designed to identify and reduce modifiable HCAI risk in adult inpatients with prolonged hospitalisation.</p><p><strong>Methods: </strong>This service evaluation was conducted across four adult inpatient wards in an acute NHS hospital in England between January and April 2026. Patients with a length of stay of at least 14 days underwent IPC review using an 11-item binary tool generating a total risk score (TRS; range of 0-11). Modifiable IPC risks were identified, and recommendations were communicated to ward teams, with patients re-reviewed according to risk level. Paired analysis compared initial and final follow-up TRS where repeat reviews were available.</p><p><strong>Results: </strong>Fifty-two patients were reviewed across 84 review episodes, comprising 52 initial and 32 follow-up reviews. Eighteen patients contributed to the paired analysis. Mean TRS decreased from 3.33 to 2.17 between initial and final review, indicating a reduction in modifiable IPC risk. Eleven patients (61.1%) improved, while six (33.3%) were unchanged. The proportion classified as low risk increased from 61.1 to 83.3% following IPC review and intervention.</p><p><strong>Discussion: </strong>This study demonstrated that a structured long-stay patient review framework could be integrated into routine IPC practice to identify and target modifiable IPC risk factors in prolonged hospital admissions.</p><p><strong>Significance and impact: </strong>The findings highlight the potential role of structured long-stay review processes within preventive and predictive IPC practice.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261495775"},"PeriodicalIF":1.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13646185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149136884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catheter's, catheter care and catheter-associated urinary tract infections (CAUTIs): A cross-sectional audit of Leicester city care homes.","authors":"Samantha Howson, Jagadeeswari Vardha, Annabelle Long, Mary Hall","doi":"10.1177/17571774261493855","DOIUrl":"https://doi.org/10.1177/17571774261493855","url":null,"abstract":"<p><strong>Background: </strong>Catheter-associated urinary tract infections (CAUTIs) cause significant costs to the health and social care system in addition to potential harm to patients. They are amongst the most common infections present in care homes and can lead to preventable hospital admissions. This study aimed to audit all care homes in Leicester City to understand the extent, treatment and management of CAUTIs, alongside the standard of catheter care.</p><p><strong>Methods: </strong>A cross-sectional audit was completed using MS Forms with care home managers over the telephone. Responses were entered directly into the online form and uploaded onto Microsoft Excel. Analysis was completed using descriptive statistics, with a pragmatic thematic analysis for free text data.</p><p><strong>Results: </strong>159 residents across 52 care homes had catheters, most commonly for urinary retention. Although 47 homes had a daily catheter care plan, just one reported use of a catheter passport. Only 14 care homes had staff trained to insert or remove catheters. Almost 3/4 of care homes had residents with a CAUTI during the reporting period and half of these were admitted to hospital as a result.</p><p><strong>Discussion: </strong>The audit highlighted many unidentified care home residents with catheters. Standards of catheter care were generally good, but variability in staff training was identified. A more centralised way of identifying residents with catheters would enable better monitoring and support of catheter-associated risks.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261493855"},"PeriodicalIF":1.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13627460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in self-assessed infection prevention and control standards compliance following accreditation in palliative care services: A mixed-methods pre-post evaluation.","authors":"Tsitsi Theologia, Giannis Polychronis, Monika Nikitara, Elena Papoui","doi":"10.1177/17571774261493860","DOIUrl":"https://doi.org/10.1177/17571774261493860","url":null,"abstract":"<p><strong>Aim/objective: </strong>To evaluate changes in self-assessed infection prevention and control (IPC) standards compliance associated with an organizational accreditation process in an independent nonprofit palliative care provider.</p><p><strong>Methods and results: </strong>A single-site mixed-methods pre-post evaluation was conducted in a 21-bed inpatient hospice. Baseline assessment occurred from May to July 2024, post-implementation assessment in October 2025, and the external survey on 24-27 November 2025. The accreditation intervention included standards review and gap analysis, creation or revision of 64 IPC procedures and criterion-related implementation elements, one comprehensive and one brief staff-training session, a pre-audit, committee oversight, and introduction of healthcare-associated infection surveillance. Six health professionals contributed baseline data and five contributed post-implementation data across 13 IPC dimensions. The overall mean score increased from 3.54 to 4.16 out of 5; the descriptive dimension-level standardized change index was 2.37. External surveyors recorded full IPC compliance. Service-user and loved-one evaluation scores increased from 1.60 to 2.00 out of 2.0. A focus group with six health professionals reported clearer procedures, improved hand hygiene, and increased perceived safety, alongside time and documentation burden. Infection-rate data were reported only as descriptive post-implementation trends because no comparable baseline existed.</p><p><strong>Discussion: </strong>Accreditation was associated with improved self-assessed IPC standards compliance, supported by external post-implementation findings. Causal inference is limited by the single-site design, small samples, and lack of a control group.</p><p><strong>Significance and impact: </strong>Accreditation can provide a structured approach to IPC improvement in palliative care, but it sustainability requires reduced documentation burden and workflow integration.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261493860"},"PeriodicalIF":1.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13627461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of an evidence-based educational program on nurses' knowledge and practice toward surgical site infection prevention: A quasi-experimental study.","authors":"Omar Qahtan Abdulazeez Abdulazeez, Senay Karadag Arli","doi":"10.1177/17571774261493097","DOIUrl":"10.1177/17571774261493097","url":null,"abstract":"<p><strong>Background: </strong>Surgical site infections (SSIs) remain a major cause of postoperative morbidity and increased healthcare costs worldwide. Evidence-based practices (EBPs) are essential for effective prevention; however, nurses' adherence is influenced by their knowledge, attitudes, and institutional training support.</p><p><strong>Aim: </strong>This study aimed to evaluate the effect of an evidence-based educational program on nurses' knowledge and practice regarding SSI prevention.</p><p><strong>Methods: </strong>A quasi-experimental pretest-posttest design with experimental and control groups was used. The study included 120 nurses (60 per group) working in surgical units at a university hospital. Data were collected between December 2023 and April 2024 using a Personal Information Form and Nurses' Knowledge and Practice Evaluation Forms. The educational program was developed based on international EBP guidelines for SSI prevention.</p><p><strong>Results: </strong>At baseline, both groups showed comparable knowledge and practice scores (<i>p</i> > .05). Following the intervention, improvements were observed in the experimental group in knowledge (<i>t</i> = 21.280, <i>p</i> < .05) and practice (<i>t</i> = 22.939, <i>p</i> < .05) scores, while no significant changes were observed in the control group. The between-group difference showed a very large effect size (Cohen's d = 4.57).</p><p><strong>Conclusions: </strong>The findings suggest that the evidence-based educational program was associated with improvements in nurses' knowledge and self-reported practices regarding SSI prevention. However, these findings should be interpreted cautiously due to the quasi-experimental design and measurement limitations.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261493097"},"PeriodicalIF":1.0,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13617148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}