Journal of Infection Prevention最新文献

{"title":"Diary.","authors":"","doi":"10.1177/17571774261427114","DOIUrl":"https://doi.org/10.1177/17571774261427114","url":null,"abstract":"","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"27 2","pages":"101-102"},"PeriodicalIF":1.0,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13009851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147512676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of bundle for prevention of infiltration in peripheral intravenous catheters in hospitalized children: A scoping review.","authors":"Amanda Nívea Lopes da Silva, Luciano Maques Dos Santos, Maria Cristina de Camargo, Andréia de Santana Souza, Sarah Deily De Oliveira Souza Santos, Patrícia Kuerten Rocha, Bianka Sousa Martins Silva","doi":"10.1177/17571774261422612","DOIUrl":"10.1177/17571774261422612","url":null,"abstract":"<p><strong>Objective: </strong>To map the scientific literature on bundles used to prevent infiltration in short peripheral intravenous catheters (SPIVC) in children.</p><p><strong>Method: </strong>A scoping review based on the Joanna Briggs Institute (JBI) guidelines, with searches conducted in the following databases: PubMed, Embase, LILACS, and Scopus. Eligible studies included those with a quantitative or mixed-methods approach, published in any language, and presenting bundles for the prevention of infiltration in SPIVC in children. Studies were excluded if they did not address bundle components, focused on a different population, involved a different type of intravenous catheter, or were unavailable in full text. Selection was performed independently by two reviewers using Rayyan© software. The study protocol was previously developed and registered in the Open Science Framework (OSF) repository.</p><p><strong>Results: </strong>Four bundles were identified, conducted in countries such as India, Australia, the United States, and Thailand. Study designs included Quality Improvement Projects (QI), prospective pre-post mixed-methods projects, and quasi-experimental prospective studies. All studies were published in English between 2014 and 2021. The number of components in the bundles ranged from 4 to 7 interventions, with \"SPIVC stabilization and dressing\" being the most frequently reported intervention.</p><p><strong>Conclusion: </strong>There is no standardization of the components in the bundles. Therefore, more robust studies are needed to establish standardized interventions.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"27 2","pages":"89-98"},"PeriodicalIF":1.0,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13009973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147512704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular access devices and hospital-onset bacteremia beyond CLABSI: An observational cohort study.","authors":"Nicholas Mielke, David Quimby, Theresa Jizba, Danielle B Dilsaver, Marlaena Nooney, Sebastian Respicio, Renuga Vivekanandan","doi":"10.1177/17571774261434725","DOIUrl":"10.1177/17571774261434725","url":null,"abstract":"<p><strong>Background: </strong>Hospital-onset bacteremia (HOB) has emerged as a broader measure of bloodstream infections beyond CLABSI, capturing infections from all vascular access devices (VADs).</p><p><strong>Objective: </strong>To evaluate the relationship between VADs and HOB in hospitalized adults.</p><p><strong>Methods: </strong>We conducted a retrospective observational study of adult patients hospitalized within a 14-hospital system from January 1, 2022, to December 31, 2023. Adult patients with a VAD and blood cultures collected ≥48 hours after admission were included. HOB was defined as a positive blood culture with a non-commensal organism obtained ≥48 hours after admission and initiation of new antimicrobials within ±2 days of the blood culture date. Logistic regression models evaluated associations between VAD type, quantity, and HOB. Multivariable models controlled for age, length of stay, sex, and comorbid cancer.</p><p><strong>Results: </strong>Among 3929 hospitalized adults, 279 (7.1%) developed HOB. Patients with HOB had a higher median number of VADs (5 vs 4, <i>p</i> < .001) and more frequently had central (54.5% vs 39.4%, <i>p</i> < .001) and arterial lines (10.9% vs 5.3%, <i>p</i> = .008). Central lines were associated with higher odds of HOB (aOR: 1.48, 95% CI: 1.15-1.91, <i>p</i> = .003), as were arterial lines (aOR: 1.45, 95% CI: 1.11-1.90, <i>p</i> = .008). Each additional VAD increased odds of HOB (aOR: 1.09, 95% CI: 1.01-1.18, <i>p</i> = .028). HOB was associated with higher in-hospital mortality (27.2% vs 16.0%, <i>p</i> < .001) with an adjusted OR of 1.81 (95% CI: 1.36-2.40, <i>p</i> < .001).</p><p><strong>Conclusions: </strong>The type and number of VADs, particularly central and arterial lines, are associated with increased odds of HOB and higher in-hospital mortality. Infection prevention strategies should focus on minimizing unnecessary VADs and closely monitoring high-risk patients.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261434725"},"PeriodicalIF":1.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12992134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of an online staff training package for parenteral nutrition administration and occurrence of central line associated bloodstream infections.","authors":"Jane Fletcher, Victoria Williams, Noreena Fitzpatrick, Naomi Rogers, Hardip Malhi, Sheldon C Cooper","doi":"10.1177/17571774261431978","DOIUrl":"10.1177/17571774261431978","url":null,"abstract":"<p><strong>Background: </strong>Parenteral nutrition (PN) is indicated for those with intestinal failure and is often administered via a central line, carrying risk of central line associated bloodstream infection (CLABSI). There is limited evidence regarding the use of an online training package for staff training in the administration of PN.</p><p><strong>Aim: </strong>Evaluate the effectiveness of an online staff training package for PN administration measured by staff feedback and incidence of CLABSI.</p><p><strong>Method: </strong>An online training package was developed using Moodle Workplace. Participants completed a tutorial, an instructional video demonstrating Standard Aseptic Non-Touch Technique (Standard-ANTT®) and an assessment. Feedback was collected anonymously via the Moodle programme and analysed using thematic analysis. CLABSI data were collected during 1/4/2024-31/3/2025. Approval was obtained via the organisation's clinical governance process.</p><p><strong>Results: </strong>Of 192 staff, 31% (<i>n</i> = 60) provided feedback; 75% reported high levels of knowledge improvement. Thematic analysis highlighted strengths of the package, including a clear instructional video and clinical relevance. Participants reported planned changes in practice, including improved hand hygiene, strict adherence to the principles of Standard-ANTT and greater confidence in PN administration. CLABSI rates reduced to 0.8/1000 catheter days compared to 1.6/1000 days in the year prior to the online training packaged.</p><p><strong>Conclusion: </strong>The online staff training package for PN was well received with staff finding it engaging, informative and practical. Course completion led to intended positive behaviour changes in clinical practice reported by participants, particularly regarding infection prevention and Standard-ANTT compliance.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261431978"},"PeriodicalIF":1.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mobile phone contamination among hospital staff: Focus on MRSA and ESBL-producing bacteria.","authors":"Rita Ghaleb, Hassan Tarhini, Ghassan Sleilaty, Ghassan Nabbout, Etienne El Melky","doi":"10.1177/17571774261431982","DOIUrl":"10.1177/17571774261431982","url":null,"abstract":"<p><strong>Background: </strong>Mobile phones are indispensable tools in hospital practice but may act as sources for healthcare-associated pathogens. Despite global concern, no prior study in Lebanon had assessed the presence of multidrug-resistant organisms (MDROs) on healthcare workers' phones.</p><p><strong>Methods: </strong>A cross-sectional observational study was conducted in a tertiary university hospital, enrolling 166 participants (125 medical staff and 41 administrative controls). Sterile swabs were collected from all phone surfaces, followed by microbiological analysis for meticillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. Participants also completed a behavioral questionnaire assessing hygiene practices.</p><p><strong>Results: </strong>The study detected universal contamination of mobile phones (100%). Two MDROs were isolated: one MRSA and one ESBL-producing Enterobacter cloacae, representing an overall prevalence of 1.2% (1.6% among medical staff). Risk behaviors were widespread: 85.6% of clinicians reported using phones in patients' presence, 34.4% interrupted clinical exams to answer calls, and only 9.6% disinfected hands afterward. Moreover, 60.8% had never disinfected their devices. The mean behavioral risk score was 5.16, significantly higher among interns (5.34) and residents (5.65) compared with administrative staff (4.39) (ANOVA, p = .01), suggesting lower risk with increasing clinical seniority.</p><p><strong>Conclusion: </strong>Our findings confirm universal contamination of mobile phones among hospital staff, with detection of MRSA and ESBL-producing bacteria among young pediatric clinicians. Although MDRO prevalence was low, high-risk behaviors were frequent, underscoring the need to reinforce basic infection prevention measures through targeted staff education. Hand hygiene continues to be the most effective strategy to limit pathogen transmission. Regular mobile phone disinfection remains a complementary measure.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261431982"},"PeriodicalIF":1.0,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reducing the incidence of <i>Clostridioides difficile</i> infection through educational and antimicrobial stewardship interventions.","authors":"Hiroki Nagaoka, Yuma Morita, Tomonori Ohya, Kazuo Takahashi, Junya Sato, Koyuru Nishio, Momoyo Miyata, Saori Iwashita, Yuta Arai, Shuntaro Kiuchi, Hiroaki Ozone, Tetsuya Matsumoto","doi":"10.1177/17571774261422616","DOIUrl":"10.1177/17571774261422616","url":null,"abstract":"<p><strong>Background: </strong><i>Clostridioides difficile</i> infection (CDI) is highly contagious, characterized by a high recurrence rate, and poses a significant challenge in hospital infection control and healthcare economics.</p><p><strong>Objective: </strong>This study aimed to investigate the impact of educational and antimicrobial stewardship interventions targeting healthcare workers on the incidence of CDI, treatment prescription patterns, and healthcare costs.</p><p><strong>Methods: </strong>This retrospective, observational study was conducted in a single acute-care hospital. Educational and antimicrobial stewardship interventions aimed at improving CDI control and treatment were implemented among healthcare workers. These interventions included hospital-wide training sessions, revision of the Infection Control Manual, dissemination of information to individual wards, and case-specific interventions. The primary outcome was changes in CDI incidence per 10,000 patient-days, comparing the 19-month periods before and after the intervention. The secondary outcomes included changes in CDI treatment prescription rates and an economic evaluation of drug costs, hospitalization fees, and infection control-related expenses between the two periods.</p><p><strong>Results: </strong>A total of 75 developed CDI in the pre-intervention period and 40 developed in the post-intervention period. The CDI incidence decreased from 4.148 to 2.103 per 10,000 patient-days, representing a 49% reduction. Additionally, the prescription rate of metronidazole decreased, whereas that of fidaxomicin increased. Although drug costs increased, the total monthly healthcare expenditures, including hospitalization expenses, decreased by 55%.</p><p><strong>Discussion: </strong>Educational and antimicrobial stewardship interventions targeting healthcare workers effectively reduced CDI incidence and improved cost-effectiveness in hospital care.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261422616"},"PeriodicalIF":1.0,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12872415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on \"Infection prevention and control in Swedish nursing homes for older adults before and after the COVID-19 pandemic\".","authors":"Indu Singh, Arvind Kumar, Nivedita Nikhil Desai, Jeffrin Reneus Paul","doi":"10.1177/17571774261422578","DOIUrl":"10.1177/17571774261422578","url":null,"abstract":"","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774261422578"},"PeriodicalIF":1.0,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12867710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of antimicrobial stewardship on healthcare-associated infections and antibiotic prescriptions in African countries: Systematic review and meta-analysis.","authors":"Sikiru Shuayb, Judith Sixsmith, Chika Robinson Okoyeuche","doi":"10.1177/17571774251377205","DOIUrl":"10.1177/17571774251377205","url":null,"abstract":"<p><strong>Background: </strong>An antimicrobial stewardship programme (AMS) aims to combat antimicrobial resistance and healthcare-associated infections (HCAIs). While studies in developed countries show AMS's effectiveness in reducing AMR and HCAIs, its impact in African countries, given differing socioeconomics, remains unclear.</p><p><strong>Objectives: </strong>To review the impact of AMS on HCAIs, antibiotic prescriptions, cost of antimicrobial procurement, and compliance with diagnostic measures for detecting resistant HCAIs in African countries.</p><p><strong>Methods: </strong>Two reviewers (S.S. and U.C.) searched databases like CINAHL, Medline, and PubMed for studies on AMS interventions in African countries, focussing on their impact on healthcare-associated infections (HCAIs) and antibiotic prescriptions. We excluded studies on outpatients, children, or those not in English and conducted a meta-analysis using data collected from changes in HCAIs before and after intervention using a random-effects model.</p><p><strong>Results: </strong>The search identified 1153 studies, of which 14 were included in the review, while four eligible studies were included in the meta-analysis. Thirteen of the 14 studies were designed using pre- and post-study methods, and one study employed a case-control method. AMS interventions effectively reduce antibiotic consumption, the cost of antibiotic procurement, and improve diagnostic measures for the detection of resistant microorganisms. The forest plot suggested a 34% reduction in HCAIs.</p><p><strong>Conclusions: </strong>In Africa, AMS interventions, whether combined or single, reduce HCAIs and antibiotic prescriptions in healthcare settings. Surgical antibiotic prophylaxis lowers HCAIs in hospitals by one-third. However, findings are cautiously generalised due to the varied quality of studies and the limited number of African countries involved.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":"27 1","pages":"3-16"},"PeriodicalIF":1.0,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12779907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145952310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparedness for infection prevention and control practice among undergraduate students: A systematic review.","authors":"Doreen Macherera Mukona, Rebecca Mathew, Atika Khalaf, Joemol Palatty, Smitha Joseph, Salimbabu Abdulla, Emma Burnett","doi":"10.1177/17571774251397197","DOIUrl":"10.1177/17571774251397197","url":null,"abstract":"<p><strong>Introduction: </strong>The World Health Organization (WHO) advocates for the strengthening of education and training in infection prevention and control (IPC) in higher educational institutions (HEIs). This is fundamental to ensure health science students are confident and competent in clinical practice.</p><p><strong>Aim: </strong>To explore the existing evidence on undergraduate health science students' preparedness for IPC practice.</p><p><strong>Methods: </strong>A systematic search was conducted in PubMed, CINAHL, Ovid, MEDLINE Complete, ProQuest, Scopus, Google Scholar, and gray literature. Quantitative and mixed-methods studies on teaching, learning, and technological approaches to Infection Prevention and Control (IPC) in undergraduate health science curricula were included. Participants were undergraduate students in medical, nursing, pharmacy, dental, physiotherapy, radiology, medical imaging, and paramedic programs. Studies published in English between 2010 and 2023 were considered.</p><p><strong>Results: </strong>Twenty studies were identified for this review. Most of the studies 11 (55%) reported improved knowledge, practice, attitudes, and confidence in IPC after implementation of technological approaches. The most reported technological approaches were didactic instruction 12 (65%) followed by virtual simulation.</p><p><strong>Discussion: </strong>There is considerable variation in the scope, content, and delivery methods for IPC in undergraduate programs. The use of traditional face-to-face teaching methods remains widespread despite its lack of interactive or practical aspects. It is important to incorporate technological methods that promote experiential learning in IPC and to develop standardized curricula for IPC at national, regional, and international levels.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774251397197"},"PeriodicalIF":1.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12634401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145587897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Observational study of 2-year data on the impact of an Antimicrobial Stewardship Committee's focused department-level audit and feedback intervention on adherence to surgical prophylaxis guidelines at a secondary care hospital in the United Arab Emirates.","authors":"Srinivasa Swamy Bandaru, Duaa Salem Jawhar, Ajmal Kuzhiyil, Magdy Imam Abdlaleem, Chaitanya Garg, Mohamed Anas","doi":"10.1177/17571774251397337","DOIUrl":"10.1177/17571774251397337","url":null,"abstract":"<p><strong>Introduction: </strong>Antimicrobial Stewardship Programs (ASPs) are critical in addressing Antimicrobial Resistance (AMR). Surgical Antibiotic Prophylaxis (SAP) guidelines provide essential guidance on antibiotic selection, administration, and duration for surgical procedures. This study evaluates the impact of department-level audit and feedback interventions within an ASP on compliance with SAP guidelines.</p><p><strong>Objective: </strong>To assess the effect of a biannual audit and feedback initiative by the Antimicrobial Stewardship Committee over 2 years on compliance with SAP guidelines regarding antibiotic selection, timing, and duration at a secondary care hospital in the UAE.</p><p><strong>Material & methods: </strong>A quasi-experimental study was conducted at a secondary care hospital in Ras Al Khaimah, UAE, comparing data from the year before (2021) and 2 years after (2022-2023) the intervention. Statistical analysis was performed using the Open Epi system. All clean and clean-contaminated surgeries meeting SAP criteria were included; contaminated and dirty surgeries were excluded.</p><p><strong>Results: </strong>The intervention significantly improved compliance with SAP guidelines. Appropriate antibiotic duration increased from 17% to 50%, and correct timing improved from 42% to 87%, both with a statistically significant <i>p</i>-value of 0.0001.</p><p><strong>Conclusions: </strong>The audit and feedback intervention significantly enhanced compliance with SAP guidelines, particularly in timing and duration, contributing to reduced surgical site infections and costs. Implementing institute-wide SAP guidelines based on local antibiogram data is recommended to support clinicians and improve compliance.</p>","PeriodicalId":16094,"journal":{"name":"Journal of Infection Prevention","volume":" ","pages":"17571774251397337"},"PeriodicalIF":1.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12615230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145540930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}